基因敲除小鼠模型市场报告：趋势、预测与竞争分析（至2031年）

受医院和科研实验室市场机会的推动，全球基因敲除小鼠模型市场预计将呈现蓬勃发展的态势。预计2025年至2031年间，全球基因敲除小鼠模型市场将以4.1%的复合年增长率成长。该市场的主要驱动因素包括：个人化医疗需求的不断增长、遗传疾病盛行率的上升以及精准研究的日益普及。

• 根据 Lucintel 的预测，条件性基因敲除小鼠在预测期内有望展现最高的成长率。
• 从应用角度来看，实验室应用预计会显示出更高的成长率。
• 从区域来看，预计亚太地区在预测期内将达到最高的成长率。

基因敲除小鼠模型市场的新兴趋势

基因敲除小鼠模型市场正受到几项重大新兴趋势的衝击，这些趋势从根本上改变了基因研究和药物发现的本质。这些趋势旨在满足临床前试验对更高精确度、效率和生物学相关性的需求。更先进的模型和整合化工作流程的出现，正帮助我们更深入地了解疾病机制。这些新兴趋势不仅提升了基因敲除小鼠的功能，也扩大了在更多科学领域的应用范围。

• CRISPR-Cas9基因编辑技术的应用：一个主要趋势是利用CRISPR-Cas9技术大规模建构基因敲除小鼠模型。这种强大的基因编辑方法比传统技术更快、更有效率、更经济。因此，开发新模型所需的时间和成本显着降低，使更多研究人员能够利用这些模型。这项技术正在加速遗传学研究的步伐，并推动更复杂、更精确的模型的发展。
• 条件性基因敲除和人源化模型的发展：建构条件性基因敲除和人源化基因敲除小鼠模型是业界日益增长的趋势。条件性基因敲除小鼠允许在特定时间或组织中敲除基因，从而能够更深入地研究基因功能。使用人类基因和组织的人源化模型为药物测试提供了一个更符合生理实际的系统。这提高了预测药物在人体中疗效和安全性的准确性，并有望显着降低药物临床试验的失败率。
• 计算生物学与人工智慧的融合：一个关键趋势是将计算生物学和人工智慧（AI）与基因敲除小鼠模型研究相结合。人工智慧正被用来解读这些模型产生的大量表型数据，并阐明未知基因的功能。这使得研究途径更加高效，并以数据主导。这种融合将使科学家能够更有效率地发现新的药物标靶，并解读复杂的基因型-表型关联，加速整个研究进程。
• 转向外包和CRO服务：市场正呈现将基因敲除小鼠模型的生产和开发外包给专业受託研究机构（CRO）的趋势。这使得生物技术和製药公司能够专注于其核心研究职能，而无需承担独立的动物饲养设施和人员带来的巨额成本。这提高了效率，降低了成本，并提供了更广泛的专业知识和专用模型。这一趋势正在扩大基因敲除小鼠的取得途径，并推动CRO产业的成长。
• 拓展至个人化医疗领域：基因敲除小鼠模型在个人化医疗领域的应用日益广泛。研究人员正在开发患者来源的异种移植模型（PDX）和其他患者特异性模型，以检验各种治疗方法对特定肿瘤和疾病的疗效。这项技术为精准医疗创造了一种宝贵的工具，能够根据患者独特的基因组构成客製化治疗方法。这种方法有望彻底改变个人化医疗，包括癌症治疗。

这些新进展共同从根本上改变了基因敲除小鼠模型产业。 CRISPR-Cas9技术的应用和先进模型开发提高了研究的精确度和生物学相关性。人工智慧的整合和外包提高了效率和可及性。个人化医疗的兴起为这些模式开启了新的高价值应用。所有这些变化共同促成了一个更具创新性、成本效益更高、更加多元化的市场，引领着现代生物医学研究的发展。

击倒小鼠模型市场的最新趋势

目前，基因敲除小鼠模型市场的发展重点在于提高模型建构和应用的速度、准确性和复杂性。这些进步源自于满足现代药物研发呈指数级增长的需求，并探索更为复杂的生物学问题。该领域正从依赖基础的组成型基因敲除转向利用最尖端科技的更精细的方法。这使得建立更贴近人类疾病的模型成为可能，并最终产生一致的临床前数据。

• CRISPR-Cas9技术的跨学科应用：CRISPR-Cas9技术在建构基因敲除小鼠模型的跨学科应用是目前最重要的进展之一。这项基因编辑技术能够以前所未有的速度和精确度建构基因敲除模型，通常只需数月而非数年即可完成。这大大缩短了新模型的建造时间，并显着加快了研究进程。这项创新使得客製化小鼠模型得以广泛应用，从而推动了整个产业的创新。
• 小鼠模型的人源化和商业化：人源化小鼠模型的商业化和标准化取得了显着进展。这些模型整合了人类基因、细胞和组织，已成为研究人类疾病（尤其是免疫学和癌症研究）更具代表性和预测性的模型。这使得研究人员能够在临床前环境中更有信心地检验特异性人类的药物和治疗方法，从而最大限度地降低临床试验失败的风险。
• 大型小鼠模型库的建立：一项重要的进展是由国际小鼠表型分析联盟（IMPC）维护的大型小鼠模型库的建立。这些模型库保存大量的基因敲除小鼠，可方便地取得数千种不同的模型。这促进了全球合作，最大限度地减少了研究重复，为大规模基因功能研究提供了标准化的资源，并加速了基因-疾病关联的鑑定。
• 条件性基因敲除系统的进展：近期研究表明，条件性基因敲除系统取得了显着进展，实现了对基因缺失的时空控制。例如，Cre-Lox系统允许在特定时间和特定组织中开启或关闭基因。这使得基因功能的分析更加灵敏和特异性，消除了胚胎致死和全局基因缺失等混杂因素，从而获得了更具定向和一致性的研究结果。
• 小鼠模型在新冠病毒研究中的应用日益广泛：近年来，小鼠模型在新冠病毒研究中的应用显着增加，这是近年来涌现的一大趋势。研究人员已建构出表达人类ACE2受体的基因敲除小鼠，并利用这些小鼠来了解病毒的致病机制，以及测试治疗方法和疫苗。这为研究新出现的病原体提供了一个快速且有效率的临床前模型。这表明基因敲除小鼠模型在应对公共卫生危机中发挥重要作用，并且具有广泛的疾病建模能力。

摘要，这些技术的综合进步正在改变基因敲除小鼠模型市场，使其更有效率、精准和先进。 CRISPR-Cas9技术的大规模应用和人源化模式的商业化提高了临床前研究的品质和适用性。大规模基因库的建构和条件性基因敲除系统的开发提高了研究的可及性和精确度。这些进步使该市场成为生物医学研究突破的关键驱动力，促进了创新和新型治疗方法的研发。

目录

第一章执行摘要

第二章 市场概览

• 背景和分类
• 供应链

第三章：市场趋势与预测分析

• 产业驱动因素与挑战
• PESTLE分析
• 专利分析
• 法规环境

4. 全球基因敲除小鼠模型市场（依类型划分）

• 吸引力分析：按类型
• 组成型基因敲除小鼠
• 条件性基因敲除小鼠
• 蛋白质功能敲除小鼠

5. 全球基因敲除小鼠模型市场（依应用划分）

• 吸引力分析：依目的
• 医院
• 研究所
• 其他的

第六章 区域分析

7. 北美击倒小鼠模型市场

• 北美击倒小鼠模型市场（按类型划分）
• 北美击倒小鼠模型市场（按应用划分）
• 美国基因敲除小鼠模型市场
• 墨西哥的击倒小鼠模型市场
• 加拿大基因敲除小鼠模型市场

8. 欧洲淘汰赛滑鼠模型市场

• 欧洲淘汰赛小鼠模型市场（按类型划分）
• 欧洲击倒小鼠模型市场按应用划分
• 德国击倒式小鼠模型市场
• 法国击倒老鼠模型市场
• 西班牙击倒老鼠模型市场
• 义大利击倒小鼠模型市场
• 英国击倒小鼠模型市场

9. 亚太地区基因敲除小鼠模型市场

• 亚太地区基因敲除小鼠模型市场（依类型划分）
• 亚太地区基因敲除小鼠模型市场（依应用划分）
• 日本击倒老鼠模型市场
• 印度击倒式老鼠模型市场
• 中国基因敲除小鼠模型市场
• 韩国击倒小鼠模型市场
• 印尼的击倒式滑鼠模型市场

10. 世界其他地区（ROW）淘汰赛滑鼠模型市场

• ROW 击倒式滑鼠模型市场类型
• ROW 击倒式滑鼠模型市场按应用划分
• 中东击倒小鼠模型市场
• 南美洲击倒老鼠模型市场
• 非洲击倒小鼠模型市场

第十一章 竞争分析

• 产品系列分析
• 营运整合
• 波特五力分析
• 市占率分析

第十二章：机会与策略分析

• 价值链分析
• 成长机会分析
• 全球基因敲除小鼠模型市场的新趋势
• 战略分析

第十三章：价值链中主要企业的概况

• 竞争分析
• Envigo
• GenOway
• Cyagen Biosciences
• Charles River Laboratories International
• TransGenic

第十四章附录

The future of the global knock out mouse model market looks promising with opportunities in the hospital and laboratory markets. The global knock out mouse model market is expected to grow with a CAGR of 4.1% from 2025 to 2031. The major drivers for this market are the increasing demand for personalized medicine, the rising prevalence of genetic disorders, and the growing adoption of precision research.

• Lucintel forecasts that, within the type category, conditional knockout mouse is expected to witness the highest growth over the forecast period.
• Within the application category, laboratory is expected to witness higher growth.
• In terms of region, APAC is expected to witness the highest growth over the forecast period.

Emerging Trends in the Knock Out Mouse Model Market

The knock out mouse model market is being transformed by some major emerging trends that are radically altering the nature of genetic research and drug discovery. These trends are responding to the imperative for increased precision, productivity, and biological relevance in preclinical studies. The trend is toward more advanced models and integrated workflows that yield richer insights into disease mechanisms. These new trends are not just advancing the functional capability of knock out mice but also broadening their applications across more scientific fields.

• CRISPR-Cas9 Gene Editing Application: One of the key trends is the use of CRISPR-Cas9 technology for creating knock out mouse models on a widespread scale. This powerful gene editing method is quicker, faster, and more efficient and cost-effective than conventional techniques. The effect is a substantial decrease in the time and cost involved to develop new models, which is more within the reach of a broad array of researchers. This technology is speeding up the pace of genetic studies and allowing the development of more complex and accurate models.
• Conditional and Humanized Model Development: The industry is witnessing an increasing trend towards the construction of conditional and humanized knock out mouse models. Conditional knock out mice enable gene deletion at a particular time or tissue, and this offers a closer study of gene function. Humanized models with human genes or tissues provide a more physiologically relevant system for drug testing. The outcome is a more reliable prediction of drug efficacy and safety in humans, which can really lower drug failure in clinical trials.
• Computational Biology-AI Integration: One of the major trends is the combination of computational biology and artificial intelligence (AI) with knock out mouse model studies. AI is utilized to interpret the huge amount of phenotypic data produced from these models and to determine the function of unidentified genes. The result is a more effective and data-oriented approach to research. This convergence assists scientists to discover new drug targets and decipher intricate genotype-phenotype associations more efficiently, speeding the whole discovery process.
• Movement towards Outsourcing and CRO Services: The market is observing a movement towards outsourcing the production and development of knock out mouse models to expert contract research organizations (CROs). This enables biotech and pharmaceutical firms to concentrate on their primary research functions without the exorbitant expense of a separate vivarium and personnel. The effect is improved efficiency, cost reduction, and access to more diversity of expertise and specialized models. This trend is democratizing access to knock out mice and facilitating growth in the CRO industry.
• Expansion into Personalized Medicine: There has been increased utilization of the knock out mouse model in personalized medicine. Scientists are developing patient-derived xenograft (PDX) and other patient-specific models on which they check the efficacy of various treatments on an individual's tumor or disease. The contribution is the creation of a very valuable tool for precision medicine, where therapies are customized based on a patient's unique genomic makeup. This method has the ability to transform cancer therapy and other therapies of a tailored nature.

Overall, these new developments are essentially transforming the knock out mouse model industry. Adoption of CRISPR-Cas9 and advanced model development are refining precision and biological validity of research. Integration of AI and outsourcing are enhancing efficiency and accessibility. The move into personalized medicine is establishing new, high-value applications for these models. These shifts are together contributing to a more innovative, cost-effective, and variable market that is cutting-edge for contemporary biomedical investigation.

Recent Developments in the Knock Out Mouse Model Market

Current advances in the knock out mouse model market are centered on enhancing the speed, accuracy, and complexity of model creation and use. The advances are necessitated by the need to keep up with the exponentially increasing requirements of contemporary drug discovery as well as explore more intricate biological questions. The field is shifting away from a dependence on basic, constitutive knock outs toward a more sophisticated approach that utilizes state-of-the-art technology to develop models that better simulate human disease, ultimately yielding more consistent preclinical information.

• Cross-Disciplinary Adoption of CRISPR-Cas9 Technology: One of the most important developments is the cross-disciplinary adoption of CRISPR-Cas9 technology for creating knock out mouse models. This gene editing technology makes it possible to produce knock outs with unrivaled speed and accuracy, frequently in a few months instead of years. The effect is a profound acceleration of the research pipeline, as it cuts dramatically the time to produce a new model. This innovation has made custom mouse models accessible to anyone and stimulated innovation across the industry.
• Humanization Commercialization of Mouse Models: Commercialization and standardization of mouse models with humanization have proceeded enormously. Such models are developed to contain human genes, cells, or tissues, and are now a better representative and predictive model for the study of human disease, notably in immunology and cancer. The benefit is the potential to have researchers test human-specific drugs and treatments in a preclinical environment with increased assurance, minimizing the risk of failure in follow-on clinical trials.
• Development of Large-Scale Mouse Model Repositories: One of the important developments is the creation of large-scale mouse model repositories, as preserved by the International Mouse Phenotyping Consortium. These repositories contain enormous collections of knock out mice, offering easy access to thousands of various models. The effect is a worldwide collaborative effort minimizing redundancy in research and offering a standardized resource for large-scale gene function study, hence speeding up the identification of gene-disease associations.
• Progress in Conditional Knock out Systems: Recent research has seen a major leap forward in conditional knock out systems that permit the spatiotemporal control of gene ablation. These systems, for example, Cre-Lox, make it possible for scientists to switch a gene on or off in a given time and tissue. The consequence is a more sensitive and specific investigation of gene function free from the confounding influences of embryonic lethality or ubiquitous gene deletion, resulting in more directed and consistent research findings.
• Enhanced Utilization of Mouse Models in COVID-19 Research: One such new trend has been the heightened utilization of mouse models in COVID-19 research. Researchers developed knock out mice that have the human ACE2 receptor to research the pathogenesis of the virus and test treatments and vaccines. The effect is a fast and efficient preclinical model for researching an emerging pathogen. It has shown the important function that knock out mouse models have in responding to public health crises and their versatility in modeling disease.

In summary, all these advances are collectively transforming the knock out mouse model market such that it is becoming more efficient, accurate, and advanced. The large-scale adoption of CRISPR-Cas9 and commercial availability of humanized models are improving the quality and applicability of preclinical studies. The organization of large repositories and development of conditional knock out systems are enhancing accessibility and accuracy. These developments are making the market a critical and active force for biomedical breakthrough, pushing innovation and new therapy development.

Strategic Growth Opportunities in the Knock Out Mouse Model Market

The knock out mouse model market has a number of strategic opportunities for growth across primary applications, fueled by its inevitability as a tool for deciphering gene function and disease. Through targeting such application-specific segments, firms can use their genetic engineering expertise to help meet some of the most critical needs in life sciences and achieve a competitive edge. The market is shifting toward increasing specialization and focus, generating new value propositions and new top-line streams beyond mere basic research into high-impact areas such as personalized medicine and therapeutic development.

• Business in Oncology and Cancer Research: A key strategic growth business opportunity exists in the use of knock out mouse models for cancer research and oncology. These models are critical to investigate tumor biology, discover novel drug targets, and to assay the effectiveness of new cancer drugs. The opportunity is to offer a broad spectrum of cancer-specific models, such as patient-derived xenografts (PDX), and to provide comprehensive preclinical services. The benefit is the potential to collaborate with biotechnology and pharmaceutical firms to speed up the development of life-saving cancer therapies.
• Expansion into Personalized Medicine: The market offers a tremendous growth potential in the use of knock out mouse models for personalized medicine. By developing patient-specific models with specific genetic mutations, scientists can try out the efficacy of various drugs and treatments prior to giving them to the patient. The market opportunity is to create and sell platforms to produce such highly customized models. The value is in having the ability to offer an enabling tool for precision medicine, resulting in improved and targeted therapies for individuals and a high-value application.
• Use in Neurodegenerative Disease Research: There is another tremendous growth opportunity in the use of knock out mouse models in research on neurodegenerative diseases like Alzheimer's and Parkinson's disease. These models are essential for examining the intricate genetic and molecular pathways of these diseases, for which there are at present few useful treatments. The potential is to supply specialized models accurately representing the human disease. The benefit is the potential to advance a field with huge unmet medical need, spurring innovation and potential breakthroughs in therapy.
• Immunology and Infectious Disease Research Growth: A strategic opportunity for growth exists in the use of knock out mouse models for infectious disease and immunology research. Humanized mouse models are especially useful here for research on the human immune response to pathogens as well as for the testing of vaccines and immunotherapies. The opportunity exists to develop and market a portfolio of humanized models. The effect is the potential to be a central contribution to global health initiatives, including the creation of vaccines for pandemics, and to enable the emerging industry of immunotherapy.
• Focusing on Academic and Government Research Institutions: One of the major growth possibilities is to focus on academic and government research institutions. Pharmaceutical corporations are large customers, but these institutions are a huge and steady market for knock out mouse models for basic research. The potential is to offer a broad variety of standardized, low-cost models and support services. The effect is extended market reach and the capability to establish long-term relationships with a wide variety of research teams, thus having an impact on future scientific breakthroughs.

Overall, these strategic opportunity growths are redefining the knock out mouse model market by emphasizing application-based requirements. By focusing on oncology, personalized medicine, neurodegenerative disorders, immunology, and the academic market, businesses are shifting towards a high-value and specialized model. This is promoting a market wherein an understanding of application needs and the provision of customized solutions are driving success, which places knock out mice as a core technology for a broad spectrum of life sciences applications.

Knock Out Mouse Model Market Driver and Challenges

The knock out mouse model market is dictated by a multifaceted interplay of key drivers propelling its growth and major pitfalls tempering its expansion. The growth of the markets is inherently driven by the escalating demand for cutting-edge tools for drug discovery and the worldwide bid to hasten biomedical research. Yet, such advancement is hampered by serious obstacles, such as ethical issues, the exorbitant cost of models, and the complexity of producing and characterizing them. The interplay between these drivers determines the direction and speed of market development.

The factors responsible for driving the knock out mouse model market include:

1. Growing Research and Development Expenditures: One major impetus is growing R&D expenditures in the biotechnology and pharmaceutical industries. Businesses feel compelled to bring new and better drugs to market for various conditions. Knock out mouse models are a must-have for preclinical evaluation and disease mechanism studies. This ongoing investment in drug development and discovery makes for a robust and consistent demand for these models, fueling growth and advancement in the market.

2. Gene Editing Technologies Advancements: The main driver is the ongoing development of gene editing technologies, especially CRISPR-Cas9. This has opened up a whole new way of producing knock out models, and the process now is quicker, more accurate, and cheaper. The technological advancements have alleviated a major bottleneck in research and enabled researchers to produce more intricate models, which in turn drives the market by increasing the capabilities and uses of knock out mice.

3. Increasing Demand for Personalized Medicine: Increasing demand for personalized and precision medicine is one of the key drivers. Personalized medicine depends on a comprehensive understanding of the genetic makeup of an individual and how it affects disease and treatment response. Patient-derived knock out mouse models are critical for testing and validating these personalized strategies. This trend is establishing a new, high-value use of knock out mice and is propelling their use in clinical research.

4. Increasing Chronic Diseases: The rising global incidence of chronic diseases like cancer, diabetes, and cardiovascular diseases is the key driver. All these diseases necessitate a large amount of research to find their underlying causes and new treatments. Knock out mice are employed to investigate the genetic origin of such conditions and to test for possible therapeutics. Increasing incidence of such diseases generates an ongoing demand for new research reagents, and hence for knock out mice.

5. Growth of Contract Research Organizations: The growth of the contract research organization sector is a major driver. Numerous pharmaceutical and biotechnology organizations are subcontracting their preclinical research to CROs to minimize costs as well as tap into specialized expertise. These CROs are heavy customers for knock out mouse models. This trend is compelling demand for both the models themselves and accompanying services, including breeding, phenotyping, and bespoke model creation, thus propelling market development.

Challenges in the knock out mouse model market are:

1. Ethical Issues and Regulatory Barriers: A major challenge is the ethical issues and strict regulatory guidelines around the use of animals in research. Public perception and animal welfare organizations may generate pressure to limit or eliminate animal testing. This necessitates a lengthy and complicated regulatory approval process for studies involving animals, which tends to delay the research and increase the expense. This ethical controversy and regulation serve as a significant restraint on the market.

2. High Model Generation and Maintenance Cost: The market is confronted with difficulty because of the high cost involved in the generation and maintenance of knock out mouse models. Establishing a new custom model is quite costly, and the constant expenses of sheltering, nourishing, and breeding a large mouse colony are out of reach for many research facilities. Such a high expenditure can be a threshold to entry for smaller laboratories and can restrict the scope of larger studies.

3. Lack of Predictive Accuracy and Complexity: The other major challenge is the complexity of disease modeling and the limitations of extrapolating predictions from mice to man. Although knock out mice are a valuable tool, they are not ideal models of human disease. The physiological differences between man and mouse can result in a lack of predictive accuracy, which is a cause of concern for drug developers. This complexity and potential for error pose a major challenge for the market.

The knock out mouse model market is witnessing dynamic growth, stimulated by the synergy of increased R&D expenditure and impressive technology developments. The trend in markets is favorably aided by increasing demand for personalized medicine and a shift in attention towards chronic disease studies. Yet, its full potential is threatened by the multifaceted challenges of ethical issues, high model costs, and the limitations inherent in animal models' ability to predict human outcomes.

List of Knock Out Mouse Model Companies

Companies in the market compete on the basis of product quality offered. Major players in this market focus on expanding their manufacturing facilities, R&D investments, infrastructural development, and leverage integration opportunities across the value chain. With these strategies knock out mouse model companies cater increasing demand, ensure competitive effectiveness, develop innovative products & technologies, reduce production costs, and expand their customer base. Some of the knock out mouse model companies profiled in this report include-

• Envigo
• GenOway
• Cyagen Biosciences
• Charles River Laboratories International
• TransGenic

Knock Out Mouse Model Market by Segment

The study includes a forecast for the global knock out mouse model market by type, application, and region.

Knock Out Mouse Model Market by Type [Value from 2019 to 2031]:

• Constitutive Knockout Mouse
• Conditional Knockout Mouse
• Protein Function Knockout Mouse

Knock Out Mouse Model Market by Application [Value from 2019 to 2031]:

• Hospital
• Laboratory
• Others

Country Wise Outlook for the Knock Out Mouse Model Market

The knock out mouse model market is a vital part of contemporary biomedical research, being an invaluable instrument for uncovering the function of genes and mechanisms of disease. Developments have been pushed forward in recent times by a convergence of sophisticated genetic engineering strategies, an expanding emphasis on personalized medicine, and the rising sophistication of therapeutic research. The market is evolving with a shift toward more sophisticated models, such as conditional and humanized mice, which provide a more accurate representation of human disease. This evolution is enabling researchers to accelerate drug discovery and develop more targeted and effective treatments for a wide range of diseases.

• United States: United States market for knock out mouse models is a world leader, backed by huge government and private investments in biomedical research. Current trends revolve around the universal adoption of CRISPR-Cas9 technology, which has optimized gene editing to be quicker, more accurate, and less expensive. There is also a strong shift towards outsourcing the generation and breeding of models to specialist contract research organizations. This market is underpinned by a robust pharmaceutical and biotechnology sector, with a special emphasis on oncology and rare disease research.
• China: China's knock out mouse model market is growing strongly, driven by high government investment in life sciences and a growing domestic biotechnology industry. Recent advances have included an emphasis on establishing large-scale mouse model repositories and an emphasis on innovative gene editing technologies. Chinese firms are providing a vast variety of custom mouse models at affordable prices, increasing accessibility to the technology. The industry also witnesses growth in partnerships between universities and private companies aimed at advancing research and development.
• Germany: The German knock out mouse model market is distinguished by a robust academic research base and a stringent quality and ethical animal care standard. Recent advances are towards the generation of highly specific and physiologically relevant conditional knock out models to evaluate gene function in a spatiotemporal fashion. German scientists also lead the way in applying these models to advanced disease fields such as neurodegeneration and immunology. The industry enjoys a mature network of research establishments and robust regulatory system to guarantee high-standard research.
• India: The Indian knock out mouse model industry is a growth-emerging market, fostered by expanding investment in life sciences R&D and a developing contract research sector. Recent trends are aiming for enhanced access to superior quality mouse models and local expertise in genetic engineering. The market is experiencing increased collaboration between Indian and overseas companies to tap expertise and technology. This expansion is further assisted by a huge reservoir of experienced scientific experts and an increasing emphasis on drug development and discovery.
• Japan: Japan's knock out mouse model market is highly advanced in terms of technology and is extremely innovative in nature, with a special emphasis on accuracy and high-level model usage. Recent advancements have seen a tendency towards the utilization of humanized mouse models for the study of immunology and infectious diseases. Japanese scientists also dominate the use of knock out mice in stem cell and regenerative medicine research. The industry is backed by a solid platform of industrial and academic research, with industry leaders heavily investing in R&D to create new-generation animal models and associated services.

Features of the Global Knock Out Mouse Model Market

• Market Size Estimates: Knock out mouse model market size estimation in terms of value ($B).
• Trend and Forecast Analysis: Market trends (2019 to 2024) and forecast (2025 to 2031) by various segments and regions.
• Segmentation Analysis: Knock out mouse model market size by type, application, and region in terms of value ($B).
• Regional Analysis: Knock out mouse model market breakdown by North America, Europe, Asia Pacific, and Rest of the World.
• Growth Opportunities: Analysis of growth opportunities in different type, application, and regions for the knock out mouse model market.
• Strategic Analysis: This includes M&A, new product development, and competitive landscape of the knock out mouse model market.

Analysis of competitive intensity of the industry based on Porter's Five Forces model.

This report answers following 11 key questions:

• Q.1. What are some of the most promising, high-growth opportunities for the knock out mouse model market by type (constitutive knockout mouse, conditional knockout mouse, and protein function knockout mouse), application (hospital, laboratory, and others), and region (North America, Europe, Asia Pacific, and the Rest of the World)?
• Q.2. Which segments will grow at a faster pace and why?
• Q.3. Which region will grow at a faster pace and why?
• Q.4. What are the key factors affecting market dynamics? What are the key challenges and business risks in this market?
• Q.5. What are the business risks and competitive threats in this market?
• Q.6. What are the emerging trends in this market and the reasons behind them?
• Q.7. What are some of the changing demands of customers in the market?
• Q.8. What are the new developments in the market? Which companies are leading these developments?
• Q.9. Who are the major players in this market? What strategic initiatives are key players pursuing for business growth?
• Q.10. What are some of the competing products in this market and how big of a threat do they pose for loss of market share by material or product substitution?
• Q.11. What M&A activity has occurred in the last 5 years and what has its impact been on the industry?

Table of Contents

1. Executive Summary

2. Market Overview

• 2.1 Background and Classifications
• 2.2 Supply Chain

3. Market Trends & Forecast Analysis

• 3.2 Industry Drivers and Challenges
• 3.3 PESTLE Analysis
• 3.4 Patent Analysis
• 3.5 Regulatory Environment

4. Global Knock Out Mouse Model Market by Type

• 4.1 Overview
• 4.2 Attractiveness Analysis by Type
• 4.3 Constitutive Knockout Mouse: Trends and Forecast (2019-2031)
• 4.4 Conditional Knockout Mouse: Trends and Forecast (2019-2031)
• 4.5 Protein Function Knockout Mouse: Trends and Forecast (2019-2031)

5. Global Knock Out Mouse Model Market by Application

• 5.1 Overview
• 5.2 Attractiveness Analysis by Application
• 5.3 Hospital: Trends and Forecast (2019-2031)
• 5.4 Laboratory: Trends and Forecast (2019-2031)
• 5.5 Others: Trends and Forecast (2019-2031)

6. Regional Analysis

• 6.1 Overview
• 6.2 Global Knock Out Mouse Model Market by Region

7. North American Knock Out Mouse Model Market

• 7.1 Overview
• 7.2 North American Knock Out Mouse Model Market by Type
• 7.3 North American Knock Out Mouse Model Market by Application
• 7.4 United States Knock Out Mouse Model Market
• 7.5 Mexican Knock Out Mouse Model Market
• 7.6 Canadian Knock Out Mouse Model Market

8. European Knock Out Mouse Model Market

• 8.1 Overview
• 8.2 European Knock Out Mouse Model Market by Type
• 8.3 European Knock Out Mouse Model Market by Application
• 8.4 German Knock Out Mouse Model Market
• 8.5 French Knock Out Mouse Model Market
• 8.6 Spanish Knock Out Mouse Model Market
• 8.7 Italian Knock Out Mouse Model Market
• 8.8 United Kingdom Knock Out Mouse Model Market

9. APAC Knock Out Mouse Model Market

• 9.1 Overview
• 9.2 APAC Knock Out Mouse Model Market by Type
• 9.3 APAC Knock Out Mouse Model Market by Application
• 9.4 Japanese Knock Out Mouse Model Market
• 9.5 Indian Knock Out Mouse Model Market
• 9.6 Chinese Knock Out Mouse Model Market
• 9.7 South Korean Knock Out Mouse Model Market
• 9.8 Indonesian Knock Out Mouse Model Market

10. ROW Knock Out Mouse Model Market

• 10.1 Overview
• 10.2 ROW Knock Out Mouse Model Market by Type
• 10.3 ROW Knock Out Mouse Model Market by Application
• 10.4 Middle Eastern Knock Out Mouse Model Market
• 10.5 South American Knock Out Mouse Model Market
• 10.6 African Knock Out Mouse Model Market

11. Competitor Analysis

• 11.1 Product Portfolio Analysis
• 11.2 Operational Integration
• 11.3 Porter's Five Forces Analysis
  • Competitive Rivalry
  • Bargaining Power of Buyers
  • Bargaining Power of Suppliers
  • Threat of Substitutes
  • Threat of New Entrants
• 11.4 Market Share Analysis

12. Opportunities & Strategic Analysis

• 12.1 Value Chain Analysis
• 12.2 Growth Opportunity Analysis
  • 12.2.1 Growth Opportunities by Type
  • 12.2.2 Growth Opportunities by Application
• 12.3 Emerging Trends in the Global Knock Out Mouse Model Market
• 12.4 Strategic Analysis
  • 12.4.1 New Product Development
  • 12.4.2 Certification and Licensing
  • 12.4.3 Mergers, Acquisitions, Agreements, Collaborations, and Joint Ventures

13. Company Profiles of the Leading Players Across the Value Chain

• 13.1 Competitive Analysis
• 13.2 Envigo
  • Company Overview
  • Knock Out Mouse Model Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 13.3 GenOway
  • Company Overview
  • Knock Out Mouse Model Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 13.4 Cyagen Biosciences
  • Company Overview
  • Knock Out Mouse Model Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 13.5 Charles River Laboratories International
  • Company Overview
  • Knock Out Mouse Model Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing
• 13.6 TransGenic
  • Company Overview
  • Knock Out Mouse Model Business Overview
  • New Product Development
  • Merger, Acquisition, and Collaboration
  • Certification and Licensing

14. Appendix

• 14.1 List of Figures
• 14.2 List of Tables
• 14.3 Research Methodology
• 14.4 Disclaimer
• 14.5 Copyright
• 14.6 Abbreviations and Technical Units
• 14.7 About Us
• 14.8 Contact Us

List of Figures

• Figure 1.1: Trends and Forecast for the Global Knock Out Mouse Model Market
• Figure 2.1: Usage of Knock Out Mouse Model Market
• Figure 2.2: Classification of the Global Knock Out Mouse Model Market
• Figure 2.3: Supply Chain of the Global Knock Out Mouse Model Market
• Figure 3.1: Driver and Challenges of the Knock Out Mouse Model Market
• Figure 3.2: PESTLE Analysis
• Figure 3.3: Patent Analysis
• Figure 3.4: Regulatory Environment
• Figure 4.1: Global Knock Out Mouse Model Market by Type in 2019, 2024, and 2031
• Figure 4.2: Trends of the Global Knock Out Mouse Model Market ($B) by Type
• Figure 4.3: Forecast for the Global Knock Out Mouse Model Market ($B) by Type
• Figure 4.4: Trends and Forecast for Constitutive Knockout Mouse in the Global Knock Out Mouse Model Market (2019-2031)
• Figure 4.5: Trends and Forecast for Conditional Knockout Mouse in the Global Knock Out Mouse Model Market (2019-2031)
• Figure 4.6: Trends and Forecast for Protein Function Knockout Mouse in the Global Knock Out Mouse Model Market (2019-2031)
• Figure 5.1: Global Knock Out Mouse Model Market by Application in 2019, 2024, and 2031
• Figure 5.2: Trends of the Global Knock Out Mouse Model Market ($B) by Application
• Figure 5.3: Forecast for the Global Knock Out Mouse Model Market ($B) by Application
• Figure 5.4: Trends and Forecast for Hospital in the Global Knock Out Mouse Model Market (2019-2031)
• Figure 5.5: Trends and Forecast for Laboratory in the Global Knock Out Mouse Model Market (2019-2031)
• Figure 5.6: Trends and Forecast for Others in the Global Knock Out Mouse Model Market (2019-2031)
• Figure 6.1: Trends of the Global Knock Out Mouse Model Market ($B) by Region (2019-2024)
• Figure 6.2: Forecast for the Global Knock Out Mouse Model Market ($B) by Region (2025-2031)
• Figure 7.1: North American Knock Out Mouse Model Market by Type in 2019, 2024, and 2031
• Figure 7.2: Trends of the North American Knock Out Mouse Model Market ($B) by Type (2019-2024)
• Figure 7.3: Forecast for the North American Knock Out Mouse Model Market ($B) by Type (2025-2031)
• Figure 7.4: North American Knock Out Mouse Model Market by Application in 2019, 2024, and 2031
• Figure 7.5: Trends of the North American Knock Out Mouse Model Market ($B) by Application (2019-2024)
• Figure 7.6: Forecast for the North American Knock Out Mouse Model Market ($B) by Application (2025-2031)
• Figure 7.7: Trends and Forecast for the United States Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 7.8: Trends and Forecast for the Mexican Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 7.9: Trends and Forecast for the Canadian Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 8.1: European Knock Out Mouse Model Market by Type in 2019, 2024, and 2031
• Figure 8.2: Trends of the European Knock Out Mouse Model Market ($B) by Type (2019-2024)
• Figure 8.3: Forecast for the European Knock Out Mouse Model Market ($B) by Type (2025-2031)
• Figure 8.4: European Knock Out Mouse Model Market by Application in 2019, 2024, and 2031
• Figure 8.5: Trends of the European Knock Out Mouse Model Market ($B) by Application (2019-2024)
• Figure 8.6: Forecast for the European Knock Out Mouse Model Market ($B) by Application (2025-2031)
• Figure 8.7: Trends and Forecast for the German Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 8.8: Trends and Forecast for the French Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 8.9: Trends and Forecast for the Spanish Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 8.10: Trends and Forecast for the Italian Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 8.11: Trends and Forecast for the United Kingdom Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 9.1: APAC Knock Out Mouse Model Market by Type in 2019, 2024, and 2031
• Figure 9.2: Trends of the APAC Knock Out Mouse Model Market ($B) by Type (2019-2024)
• Figure 9.3: Forecast for the APAC Knock Out Mouse Model Market ($B) by Type (2025-2031)
• Figure 9.4: APAC Knock Out Mouse Model Market by Application in 2019, 2024, and 2031
• Figure 9.5: Trends of the APAC Knock Out Mouse Model Market ($B) by Application (2019-2024)
• Figure 9.6: Forecast for the APAC Knock Out Mouse Model Market ($B) by Application (2025-2031)
• Figure 9.7: Trends and Forecast for the Japanese Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 9.8: Trends and Forecast for the Indian Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 9.9: Trends and Forecast for the Chinese Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 9.10: Trends and Forecast for the South Korean Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 9.11: Trends and Forecast for the Indonesian Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 10.1: ROW Knock Out Mouse Model Market by Type in 2019, 2024, and 2031
• Figure 10.2: Trends of the ROW Knock Out Mouse Model Market ($B) by Type (2019-2024)
• Figure 10.3: Forecast for the ROW Knock Out Mouse Model Market ($B) by Type (2025-2031)
• Figure 10.4: ROW Knock Out Mouse Model Market by Application in 2019, 2024, and 2031
• Figure 10.5: Trends of the ROW Knock Out Mouse Model Market ($B) by Application (2019-2024)
• Figure 10.6: Forecast for the ROW Knock Out Mouse Model Market ($B) by Application (2025-2031)
• Figure 10.7: Trends and Forecast for the Middle Eastern Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 10.8: Trends and Forecast for the South American Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 10.9: Trends and Forecast for the African Knock Out Mouse Model Market ($B) (2019-2031)
• Figure 11.1: Porter's Five Forces Analysis of the Global Knock Out Mouse Model Market
• Figure 11.2: Market Share (%) of Top Players in the Global Knock Out Mouse Model Market (2024)
• Figure 12.1: Growth Opportunities for the Global Knock Out Mouse Model Market by Type
• Figure 12.2: Growth Opportunities for the Global Knock Out Mouse Model Market by Application
• Figure 12.3: Growth Opportunities for the Global Knock Out Mouse Model Market by Region
• Figure 12.4: Emerging Trends in the Global Knock Out Mouse Model Market

List of Tables

• Table 1.1: Growth Rate (%, 2023-2024) and CAGR (%, 2025-2031) of the Knock Out Mouse Model Market by Type and Application
• Table 1.2: Attractiveness Analysis for the Knock Out Mouse Model Market by Region
• Table 1.3: Global Knock Out Mouse Model Market Parameters and Attributes
• Table 3.1: Trends of the Global Knock Out Mouse Model Market (2019-2024)
• Table 3.2: Forecast for the Global Knock Out Mouse Model Market (2025-2031)
• Table 4.1: Attractiveness Analysis for the Global Knock Out Mouse Model Market by Type
• Table 4.2: Market Size and CAGR of Various Type in the Global Knock Out Mouse Model Market (2019-2024)
• Table 4.3: Market Size and CAGR of Various Type in the Global Knock Out Mouse Model Market (2025-2031)
• Table 4.4: Trends of Constitutive Knockout Mouse in the Global Knock Out Mouse Model Market (2019-2024)
• Table 4.5: Forecast for Constitutive Knockout Mouse in the Global Knock Out Mouse Model Market (2025-2031)
• Table 4.6: Trends of Conditional Knockout Mouse in the Global Knock Out Mouse Model Market (2019-2024)
• Table 4.7: Forecast for Conditional Knockout Mouse in the Global Knock Out Mouse Model Market (2025-2031)
• Table 4.8: Trends of Protein Function Knockout Mouse in the Global Knock Out Mouse Model Market (2019-2024)
• Table 4.9: Forecast for Protein Function Knockout Mouse in the Global Knock Out Mouse Model Market (2025-2031)
• Table 5.1: Attractiveness Analysis for the Global Knock Out Mouse Model Market by Application
• Table 5.2: Market Size and CAGR of Various Application in the Global Knock Out Mouse Model Market (2019-2024)
• Table 5.3: Market Size and CAGR of Various Application in the Global Knock Out Mouse Model Market (2025-2031)
• Table 5.4: Trends of Hospital in the Global Knock Out Mouse Model Market (2019-2024)
• Table 5.5: Forecast for Hospital in the Global Knock Out Mouse Model Market (2025-2031)
• Table 5.6: Trends of Laboratory in the Global Knock Out Mouse Model Market (2019-2024)
• Table 5.7: Forecast for Laboratory in the Global Knock Out Mouse Model Market (2025-2031)
• Table 5.8: Trends of Others in the Global Knock Out Mouse Model Market (2019-2024)
• Table 5.9: Forecast for Others in the Global Knock Out Mouse Model Market (2025-2031)
• Table 6.1: Market Size and CAGR of Various Regions in the Global Knock Out Mouse Model Market (2019-2024)
• Table 6.2: Market Size and CAGR of Various Regions in the Global Knock Out Mouse Model Market (2025-2031)
• Table 7.1: Trends of the North American Knock Out Mouse Model Market (2019-2024)
• Table 7.2: Forecast for the North American Knock Out Mouse Model Market (2025-2031)
• Table 7.3: Market Size and CAGR of Various Type in the North American Knock Out Mouse Model Market (2019-2024)
• Table 7.4: Market Size and CAGR of Various Type in the North American Knock Out Mouse Model Market (2025-2031)
• Table 7.5: Market Size and CAGR of Various Application in the North American Knock Out Mouse Model Market (2019-2024)
• Table 7.6: Market Size and CAGR of Various Application in the North American Knock Out Mouse Model Market (2025-2031)
• Table 7.7: Trends and Forecast for the United States Knock Out Mouse Model Market (2019-2031)
• Table 7.8: Trends and Forecast for the Mexican Knock Out Mouse Model Market (2019-2031)
• Table 7.9: Trends and Forecast for the Canadian Knock Out Mouse Model Market (2019-2031)
• Table 8.1: Trends of the European Knock Out Mouse Model Market (2019-2024)
• Table 8.2: Forecast for the European Knock Out Mouse Model Market (2025-2031)
• Table 8.3: Market Size and CAGR of Various Type in the European Knock Out Mouse Model Market (2019-2024)
• Table 8.4: Market Size and CAGR of Various Type in the European Knock Out Mouse Model Market (2025-2031)
• Table 8.5: Market Size and CAGR of Various Application in the European Knock Out Mouse Model Market (2019-2024)
• Table 8.6: Market Size and CAGR of Various Application in the European Knock Out Mouse Model Market (2025-2031)
• Table 8.7: Trends and Forecast for the German Knock Out Mouse Model Market (2019-2031)
• Table 8.8: Trends and Forecast for the French Knock Out Mouse Model Market (2019-2031)
• Table 8.9: Trends and Forecast for the Spanish Knock Out Mouse Model Market (2019-2031)
• Table 8.10: Trends and Forecast for the Italian Knock Out Mouse Model Market (2019-2031)
• Table 8.11: Trends and Forecast for the United Kingdom Knock Out Mouse Model Market (2019-2031)
• Table 9.1: Trends of the APAC Knock Out Mouse Model Market (2019-2024)
• Table 9.2: Forecast for the APAC Knock Out Mouse Model Market (2025-2031)
• Table 9.3: Market Size and CAGR of Various Type in the APAC Knock Out Mouse Model Market (2019-2024)
• Table 9.4: Market Size and CAGR of Various Type in the APAC Knock Out Mouse Model Market (2025-2031)
• Table 9.5: Market Size and CAGR of Various Application in the APAC Knock Out Mouse Model Market (2019-2024)
• Table 9.6: Market Size and CAGR of Various Application in the APAC Knock Out Mouse Model Market (2025-2031)
• Table 9.7: Trends and Forecast for the Japanese Knock Out Mouse Model Market (2019-2031)
• Table 9.8: Trends and Forecast for the Indian Knock Out Mouse Model Market (2019-2031)
• Table 9.9: Trends and Forecast for the Chinese Knock Out Mouse Model Market (2019-2031)
• Table 9.10: Trends and Forecast for the South Korean Knock Out Mouse Model Market (2019-2031)
• Table 9.11: Trends and Forecast for the Indonesian Knock Out Mouse Model Market (2019-2031)
• Table 10.1: Trends of the ROW Knock Out Mouse Model Market (2019-2024)
• Table 10.2: Forecast for the ROW Knock Out Mouse Model Market (2025-2031)
• Table 10.3: Market Size and CAGR of Various Type in the ROW Knock Out Mouse Model Market (2019-2024)
• Table 10.4: Market Size and CAGR of Various Type in the ROW Knock Out Mouse Model Market (2025-2031)
• Table 10.5: Market Size and CAGR of Various Application in the ROW Knock Out Mouse Model Market (2019-2024)
• Table 10.6: Market Size and CAGR of Various Application in the ROW Knock Out Mouse Model Market (2025-2031)
• Table 10.7: Trends and Forecast for the Middle Eastern Knock Out Mouse Model Market (2019-2031)
• Table 10.8: Trends and Forecast for the South American Knock Out Mouse Model Market (2019-2031)
• Table 10.9: Trends and Forecast for the African Knock Out Mouse Model Market (2019-2031)
• Table 11.1: Product Mapping of Knock Out Mouse Model Suppliers Based on Segments
• Table 11.2: Operational Integration of Knock Out Mouse Model Manufacturers
• Table 11.3: Rankings of Suppliers Based on Knock Out Mouse Model Revenue
• Table 12.1: New Product Launches by Major Knock Out Mouse Model Producers (2019-2024)
• Table 12.2: Certification Acquired by Major Competitor in the Global Knock Out Mouse Model Market