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市场调查报告书
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膝关节软骨修復市场增长、趋势、COVID-19 的影响和预测 (2023-2028)

Knee Cartilage Repair Market - Growth, Trends, and Forecasts (2023 - 2028)
出版日期: | 出版商: Mordor Intelligence | 英文 120 Pages | 商品交期: 2-3个工作天内

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简介目录

膝关节软骨修復市场预计在预测期内（2022 年至 2027 年）的复合年增长率为 6.2%。

在 COVID-19 大流行期间，所研究的市场因供应链问题和漫长的等待时间而受到不利影响。 例如，2021 年 8 月，开展了一项名为“COVID-19 疫情对骨科手术的影响”的研究。 根据对大流行第一年的全国分析，在大流行的第一年，智利的骨科手术数量下降了 22.8%。 所有外科手术都会受到不利影响，骨折和外伤手术受影响最小。 膝关节置换术 (-64%) 的副作用最大，其次是髋关节置换术 (-41%) 和膝关节韧带重建术 (-44%)。 COVID-19 的爆发减少了 2020 年骨科手术的数量，但它肯定对择期手术产生了重大的负面影响，因为公共卫生网络的恢復速度比私人设施慢。 等待名单预计会增加，扩大骨科手术的差距，这最终会影响未来几年的市场增长率。

交通事故和运动损伤的增加以及人口老龄化以及对微创手术的日益偏好等因素正在推动市场增长。 例如，2021 年 10 月，世界卫生组织发表了一篇题为“年龄与健康”的文章，其中指出，到 2030 年，全球将有六分之一的人超过 60 岁。 60 岁及以上人口的比例将从 2020 年的 10 亿增加到 14 亿。 到 2050 年，全球 60 岁及以上人口将翻一番，达到 21 亿。 从 2020 年到 2050 年，80 岁及以上的人口数量预计将增加两倍，达到 4.26 亿。 衰老会损害膝关节健康，增加损伤膝关节软骨的机会，因此需要治疗。 因此，老年人口的增加将推动膝关节手术的需求并推动市场的增长。

同样，交通事故的增加也是推动市场增长的因素之一。 例如，2021 年 10 月，美国国家公路安全管理局 (ANSR) 报告称，与两个月前的下降相比，死亡人数增加了 42.5%，重伤事故占 2.4%，轻伤事故占 11.6%与8月相比上升了9.1%，宣布该指数出现转折恶化。 文件显示，2021年8月葡萄牙道路共发生交通事故2996起，死亡57人，重伤217人，轻伤3644人。 因此，受伤人数的增加将增加对膝关节软骨治疗的需求，预计这将推动未来几年的市场增长。

同样，对微创手术的日益偏爱预计也将促进市场增长。 例如，2021 年 1 月，发表了一项名为“使用扩展关节镜进行微创膝关节手术的增强现实导航”的研究，指出在微创膝关节手术中，外科医生可以使用手术工具和关节镜通过一个小切口插入。并且治疗由二维关节镜图像辅助。 与 2D 关节镜导航相比，所提出的增强现实导航在膝关节模型和体外猪膝关节实验中分别将指向误差减少了 2.10 毫米和 2.70 毫米。 因此，随着技术的进步，对微创手术的偏好将会增加，从而支持市场的增长。

此外，2021 年 7 月，Hyalex Orthopedics, Inc. 的 HYALEX 软骨系统获得了美国食品和药物管理局 (FDA) 授予的突破性器械称号。 HYALEX 软骨系统旨在修復软骨缺损并恢復□□因膝关节软骨或骨缺损而需要手术的患者的功能。

因此，由于上述因素，市场有望在未来增长。 然而，高昂的治疗成本可能会阻碍预测期内的市场增长。

膝关节软骨修復市场趋势

在预测期内，关节镜软骨成形术领域预计将占据重要的市场份额

软骨成形术用于润滑膝盖中受损的软骨并减少关节内的摩擦。 越来越多的研究调查等因素正在推动这一领域的增长。 已经发表了各种研究报告，以提供对所研究细分市场的见解。 例如，2021 年 8 月发表了一篇题为“关节镜后软骨下不全骨折的膝关节屈服于关节成形术的高转化率”的研究论文，指出膝关节的关节镜下软骨下不全骨折 (SIFKs) 受内侧损伤影响最大隔间。他说这经常发生。 这些患者 (75%) 的半月板根部和桡骨破裂很明显。 最终，关节病进展 (33%)，最终关节置换手术的发生率很高。

同样，2022 年 1 月发表的另一项名为“射频在关节软骨病变治疗中的关节镜应用”的研究发现，接受膝关节镜检查的患者中，超过 60% 的软骨厚度不全。缺陷是可检测的，并且髌骨外桥 III 级病变占主导地位。 在这项研究中，我们调查了 15 名接受膝关节镜射频软骨成形术的患者。 与术前相比，这些患者的临床结果显着改善。

此外，产品发布也在推动市场的增长。 例如，2021 年 2 月，美国食品和药物管理局授予 Geistlich Pharma 的 Chondro-Gide 关节软骨覆盖物突破性装置 (BDD)。 Chondro Guide 是一种胶原蛋白膜，用于单步软骨修復技术。

因此，由于上述因素，市场预计在预测期内会出现增长。

北美有望在预测期内主导市场

膝关节软骨修復市场以北美为中心。 疾病发病率增加、技术进步、研究和资助等因素正在推动市场增长。 正在研究各种新技术以提供更好的治疗方法。 例如，2021 年 10 月，一项名为“用于椎间盘和膝关节软骨修復的 3D 生物打印植入物”的研究发表，表明在过去的二十年中，人们对软骨组织工程领域的兴趣越来越大，这已被用于开发细胞、生长因子 (GF)，称 3D 生物打印等技术可用于使用生物相容性材料的组合来生成功能性结构。 3D 生物打印使我们能够定制开发结构的机械性能，以确保所需的刚度来支撑重量，同时在植入后保持所需的灵活性。

同样，2021 年 12 月发表的另一项题为“使用多阶段卷积神经网络自动分割膝关节软骨和骨骼：来自骨关节炎倡议的数据”的研究发现，MR 他们学习了一个框架，可以从图像中自动分割膝关节软骨和骨骼，实现不同疾病严重程度的高效准确量化。 这项研究由加拿大自然科学和工程研究委员会资助。

此外，产品发布是推动该地区增长的另一个因素。 例如，2020 年 12 月，全球微创骨科技术领导者 Arthrex 在美国食品和药物管理局批准其 SwiveLock ACL 修復锚后，宣布推出 SwiveLock ACL 修復套件。。 该套件是首批获得 FDA 批准用于前交叉韧带断裂初级修復的套件之一。 预计此类发布将促进市场增长。

因此，此类进步可能会在未来以更高效的产品促进市场增长。

膝关节软骨修復市场竞争者分析

市场部分分散，由几个主要参与者组成。 从市场份额的角度来看，一些主要参与者主导着市场。 目前主导市场的公司包括 B. Braun Melsungen AG、ISTO Technologies, Inc.、Smith & Nephew、Stryker 和 Zimmer Biomet Holdings, Inc.。

其他好处

  • Excel 格式的市场预测 (ME) 表
  • 三个月的分析师支持

内容

第1章介绍

  • 研究假设和市场定义
  • 调查范围

第2章研究方法论

第 3 章执行摘要

第4章市场动态

  • 市场概览
  • 市场驱动力
    • 老年人口增加
    • 交通事故和运动伤害增加
    • 越来越喜欢微创手术
  • 市场製约因素
    • 高昂的治疗费用
  • 波特的五力分析
    • 新进入者的威胁
    • 买方/消费者议价能力
    • 供应商的议价能力
    • 替代品的威胁
    • 竞争公司之间的敌对关係

第 5 章市场细分（基于价值的市场规模：百万美元）

  • 通过申请
    • 关节镜软骨移植
    • 自体培养软骨移植
    • 基于细胞的软骨表面重修
    • 骨软骨成形术
    • 其他
  • 最终用户
    • 医院
    • 门诊手术中心
    • 骨科诊所
  • 按地区
    • 北美
      • 美国
      • 加拿大
      • 墨西哥
    • 欧洲
      • 德国
      • 英国
      • 法国
      • 意大利
      • 西班牙
      • 其他欧洲地区
    • 亚太地区
      • 中国
      • 日本
      • 印度
      • 澳大利亚
      • 韩国
      • 其他亚太地区
    • 中东
      • 海湾合作委员会
      • 南非
      • 其他中东地区
    • 南美洲
      • 巴西
      • 阿根廷
      • 其他南美洲

第6章竞争格局

  • 公司简介
    • Anika Therapeutics, Inc
    • Arthrex, Inc
    • B. Braun Melsungen AG
    • CartiHeal, Inc
    • CONMED Corporation
    • ISTO Technologies, Inc.
    • Johnson & Johnson（DePuy Synthes）
    • MEDIPOST Co. Ltd.
    • Smith & Nephew
    • Stryker
    • Vericel Corporation
    • Zimmer Biomet Holdings, Inc.

第7章 市场机会与今后动向

简介目录
Product Code: 90525

The Knee Cartilage Repair Market is projected to register a CAGR of 6.2% during the forecast period (2022- 2027).

During the COVID-19 pandemic, the studied market was adversely affected due to supply chain issues and long waiting times. For instance, in August 2021, a research study titled "Impact of the COVID-19 Outbreak on Orthopedic Surgery: A Nationwide Analysis of the First Pandemic Year" stated that the number of orthopedic surgeries fell by 22.8% during the first year of the pandemic in Chile. All surgical procedures were adversely affected, with fracture and trauma surgeries being the least affected. The maximum adverse impact was seen in knee arthroplasty (-64%), followed by hip arthroplasty (-41%) and knee ligament reconstruction (-44%). The COVID-19 outbreak reduced the number of orthopedic procedures during 2020, as public health networks did have a more significant adverse impact on elective surgeries due to a slower recovery than private institutions. An increase in the waiting list should be expected, which will widen the access gap to orthopedic surgery, ultimately impacting the market growth rate over the coming years.

Factors such as the increasing geriatric population coupled with increasing road and sports-related injuries and a rising preference for minimally invasive surgeries are driving the market growth. For instance, an article published by the World Health Organization titled "Age and Health" in October 2021 stated that by 2030, 1 in 6 people worldwide would be 60 years or older. The share of the population aged 60 years and over will increase from 1 billion in 2020 to 1.4 billion. By 2050, the world's population of people aged 60 years and older will double (to 2.1 billion). The number of people aged 80 years or older is expected to triple between 2020 and 2050 to reach 426 million. Aging may hurt knee health, and thus, there will be an increased chance of knee cartilage damage and thus it will require treatment. Hence, growth in the geriatric population, thereby drive the demand for knee surgeries, in turn boosting the market's growth.

Similarly, rising road accidents are another factor augmenting the market's growth. For instance, in October 2021, the National Road Safety Authority (ANSR) stated that there was a worsening in the evolution of the indicators, with a growth of 42.5% in fatalities, in contrast to the reductions of the two previous months, and an increase of 9.1% in the number of accidents, from 2.4% for serious injuries and 11.6% for minor injuries, compared to August 2020. According to the same document, in August 2021, there were 2,996 road accidents on Portuguese roads, which caused 57 deaths, 217 serious injuries, and 3,644 minor injuries. As a result, rising injuries will increase the demand for knee cartilage treatment, driving market growth in the coming years.

Similarly, a rising preference for minimally invasive surgeries would increase market growth. For instance, in January 2021, a research study published titled "Augmented reality navigation for minimally invasive knee surgery using enhanced arthroscopy" stated that during minimally invasive knee surgery, surgeons insert surgical instruments and arthroscopy through small incisions and implement treatment assisted by 2D arthroscopic images. Compared with 2D arthroscopic navigation, the proposed augmented reality navigation reduced the targeting errors by 2.10 mm and 2.70 mm for knee phantom and in vitro swine knee experiments, respectively. Thus, with technological advancements, the preference for minimally invasive surgeries will increase and support the market's growth.

Additionally, in July 2021, the HYALEX Cartilage System by Hyalex Orthopaedics, Inc. was granted Breakthrough Device Designation by the United States Food and Drug Administration (FDA). The HYALEX Cartilage System is intended to repair cartilage defects and restore function for patients with loss of knee articular cartilage and bone requiring surgery.

Thus, the abovementioned factors will increase the market's growth in the upcoming period. However, the high cost of treatment may hinder the market's growth over the forecast period.

Knee Cartilage Repair Market Trends

Arthroscopic Chondroplasty Segment is Expected to Hold a Significant Market Share Over the Forecast Period

Chondroplasty is performed to smooth damaged cartilage in the knee to lessen friction in the joint. Factors such as increasing research studies are driving the segment's growth. Various research studies have been published to provide insight into the studied segment. For instance, in August 2021, a published research paper titled "Post-arthroscopic Subchondral Insufficiency Fractures of the Knee Yield High Rate of Conversion to Arthroplasty" stated that post-arthroscopic subchondral insufficiency fracture of the knee (SIFK) most commonly occurs in the medial compartment. Meniscal root and radial tears in these patients are notable (75%). Ultimately, there is a high rate of progression of arthrosis (33%) and eventual conversion to arthroplasty.

Similarly, another research study published in January 2022, titled "The Arthroscopic Application of Radiofrequency in Treatment of Articular Cartilage Lesions," stated that knee arthroscopy partial-thickness cartilage defects can be detected in more than 60% of the cases that received knee arthroscopy, with Outerbridge Grade III lesions of the patella being the dominant one. The study investigated 15 patients who underwent knee arthroscopic radiofrequency chondroplasty. The clinical results of these patients were significantly improved compared with their preoperative status.

Additionally, the launch of products is also augmenting the market's growth. For instance, in February 2021, the United States Food and Drug Administration granted Chondro-Gide articular cartilage cover by Geistlich Pharma a Breakthrough Device (BDD). Chondro-Gide is a collagen membrane used in a single-step cartilage repair technique.

Thus, owing to the abovementioned factors, the market segment is expected to show growth over the forecast period.

North America is Expected to Dominate the Market Over the Forecast Period

The North American market is dominating the knee cartilage repair market. Factors such as the increasing incidence of diseases, technological advancements, research studies, and grants are increasing the market's growth. Various new technologies have been considered to provide better care. For instance, in October 2021, a research study published titled "3D Bioprinted Implants for Cartilage Repair in Intervertebral Discs and Knee Menisci" stated that there had been increasing interest in the past two decades in the area of cartilage tissue engineering where methods like 3D bioprinting may be implemented to generate functional constructs using a combination of cells, growth factors (GF), and biocompatible materials. 3D bioprinting allows for the modulation of the mechanical properties of the developed constructs to maintain the required flexibility following implantation while also providing the stiffness needed to support body weight.

Similarly, another research study published in December 2021 titled "Automatic knee cartilage and bone segmentation using multi-stage convolutional neural networks: data from the osteoarthritis initiative" stated that the framework learns to automatically segment knee cartilage tissues and bones from MR images acquired with two sequences, producing efficient, accurate quantifications at varying disease severities. The study received a grant from Canada's Natural Sciences and Engineering Research Council.

Furthermore, product launches are another factor in the growth of the region. For instance, in December 2020, Arthrex, a global leader in minimally invasive orthopedic technology, announced the launch of the SwiveLock ACL Repair Kit, following clearance by the United States Food and Drug Administration of the SwiveLock anchor for ACL repair. It is one of the first FDA-cleared kits for the primary repair of anterior cruciate ligament (ACL) tears. Such launches would increase the market's growth.

Hence, with such advancements, the market's growth would increase due to more efficient products in the future.

Knee Cartilage Repair Market Competitor Analysis

The market is partially fragmented and consists of several major players. In terms of market share, a few major players dominate the market. Some of the companies which are currently dominating the market are B. Braun Melsungen AG, ISTO Technologies, Inc., Smith & Nephew, Stryker, and Zimmer Biomet Holdings, Inc., among others.

Additional Benefits:

  • The market estimate (ME) sheet in Excel format
  • 3 months of analyst support

TABLE OF CONTENTS

1 INTRODUCTION

  • 1.1 Study Assumptions and Market Definition
  • 1.2 Scope of the Study

2 RESEARCH METHODOLOGY

3 EXECUTIVE SUMMARY

4 MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Increasing Geriatric Population
    • 4.2.2 Increasing Road and Sports Related Injuries
    • 4.2.3 Increasing Preference for Minimally Invasive Surgeries
  • 4.3 Market Restraints
    • 4.3.1 High Cost of Treatment
  • 4.4 Porter's Five Forces Analysis
    • 4.4.1 Threat of New Entrants
    • 4.4.2 Bargaining Power of Buyers/Consumers
    • 4.4.3 Bargaining Power of Suppliers
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5 MARKET SEGMENTATION (Market Size by Value - USD million)

  • 5.1 By Application
    • 5.1.1 Arthroscopic Chondroplasty
    • 5.1.2 Autologous Chondrocyte Implantation
    • 5.1.3 Cell-based Cartilage Resurfacing
    • 5.1.4 Osteochondral Grafts Transplantation
    • 5.1.5 Others
  • 5.2 By End User
    • 5.2.1 Hospitals
    • 5.2.2 Ambulatory Surgical Centers
    • 5.2.3 Orthopedic Clinics
  • 5.3 Geography
    • 5.3.1 North America
      • 5.3.1.1 United States
      • 5.3.1.2 Canada
      • 5.3.1.3 Mexico
    • 5.3.2 Europe
      • 5.3.2.1 Germany
      • 5.3.2.2 United Kingdom
      • 5.3.2.3 France
      • 5.3.2.4 Italy
      • 5.3.2.5 Spain
      • 5.3.2.6 Rest of Europe
    • 5.3.3 Asia-Pacific
      • 5.3.3.1 China
      • 5.3.3.2 Japan
      • 5.3.3.3 India
      • 5.3.3.4 Australia
      • 5.3.3.5 South Korea
      • 5.3.3.6 Rest of Asia-Pacific
    • 5.3.4 Middle-East
      • 5.3.4.1 GCC
      • 5.3.4.2 South Africa
      • 5.3.4.3 Rest of Middle-East
    • 5.3.5 South America
      • 5.3.5.1 Brazil
      • 5.3.5.2 Argentina
      • 5.3.5.3 Rest of South America

6 COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 Anika Therapeutics, Inc
    • 6.1.2 Arthrex, Inc
    • 6.1.3 B. Braun Melsungen AG
    • 6.1.4 CartiHeal, Inc
    • 6.1.5 CONMED Corporation
    • 6.1.6 ISTO Technologies, Inc.
    • 6.1.7 Johnson & Johnson (DePuy Synthes)
    • 6.1.8 MEDIPOST Co. Ltd.
    • 6.1.9 Smith & Nephew
    • 6.1.10 Stryker
    • 6.1.11 Vericel Corporation
    • 6.1.12 Zimmer Biomet Holdings, Inc.

7 MARKET OPPORTUNITIES AND FUTURE TRENDS