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蛋白 A 树脂市场 - 增长、趋势和预测 (2023-2028)
市场调查报告书
商品编码
1273444

蛋白 A 树脂市场 - 增长、趋势和预测 (2023-2028)

Protein A Resin Market - Growth, Trends, and Forecasts (2023 - 2028)
出版日期: | 出版商: Mordor Intelligence | 英文 117 Pages | 商品交期: 2-3个工作天内

价格

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简介目录

在预测期内，蛋白 A 树脂市场预计将以 8.5% 左右的复合年增长率增长。

COVID-19 疾病的出现对大流行期间的市场增长产生了显着影响。 这种突然爆发对生产有效诊断和高度安全的 COVID-19 治疗产生了前所未有的需求。 这种情况吸引了市场参与者采用蛋白 A 树脂生产 COVID-19 疫苗，从而影响了市场的增长。 例如，2021 年 2 月，Prepligen 与 Navigo Proteins 合作开发了一种专有纯化树脂，即 NGL COVID-19 Spike 蛋白亲和树脂。 该树脂用于纯化 COVID-19 疫苗，并用于与结合受体结合域的 SARS-CoV-2 刺突蛋白结合。 因此，这些发展对大流行期间的市场增长产生了决定性影响。 此外，预计 SARS-CoV-2 病毒突变株的出现将继续维持对蛋白 A 树脂的需求，从而促进预测期内的市场增长。

蛋白 A 树脂市场的增长在很大程度上是由全球慢性病负担的增加以及对治疗慢性病的抗体疗法的需求不断增长所推动的。. 此外，蛋白A树脂在诊断各种慢性病方面的功效也有望推动市场增长。 例如，2021 年 5 月发表的一篇 NCBI 论文提到使用低成本的热泳适体传感器 (TAS) 来分析血浆 EV 的癌症相关蛋白谱，而不受可溶性蛋白的干扰。它已经做到了。 这表明蛋白质分析在区分转移性乳腺癌、非转移性乳腺癌和健康供体 (HD) 方面具有 91.1% 的高精度。 因此，证明蛋白 A 树脂在癌症诊断中的有效性的研究有望促进市场增长。

此外，慢性病负担的增加也有望促进市场增长。 例如，根据 2022 年 2 月发布的 WHO 情况说明书，估计 2021 年美国将有 190 万新诊断的癌症患者。 另据介绍，全球每年约有40万儿童患上癌症。 宫颈癌在 23 个国家最常见，包括埃斯瓦蒂尼、印度、南非和南美洲。 还有许多癌症，例如乳腺癌、肺癌、结直肠癌和前列腺癌。

虽然有几个因素促进了市场增长，但与蛋白 A 树脂相关的高成本预计会在预测期内阻碍市场增长。

蛋白A树脂市场趋势

预计製药和生物製药公司将主导最终用户领域

蛋白质分析在製药和生物製药行业的药物发现和开发中发挥着非常重要的作用，因为製药和生物製药公司主要以蛋白质为目标。 蛋白质分析的常见应用包括目标识别和表征、从现成的生物体液中鑑定功效和毒性生物标誌物，以及研究功效和毒性的机制。由于生物製药项目中正在进行的大量药物开发项目，预计将有显着增长.

政府增加对药物研发的资助以及分析仪器领域的技术进步预计将推动研究领域的增长。 此外，生命科学研发支出的增加、药物发现的进展、色谱法的采用增加等是推动製药和生物製药行业蛋白 A 树脂市场增长的主要因素。 例如，EFPIA 在 2022 年发布的数据中提到，2021 年欧洲製药业的研发支出为 4150 万欧元（4460 万美元）。 预计如此高的医药支出将推动药物开发研究和各种诊断测试对蛋白 A 树脂的需求，从而推动研究领域的增长。

此外，为满足製药和生物製药行业的需求而增加的产品发布预计也将促进市场增长。 例如，2021 年 9 月，漂莱特将推出两款新的下一代层析树脂 Praesto Jetted A50 HipH 和 Praesto Jetted dt 18-，以解决其包括抗体、疫苗和基因疗法在内的生物分子管道的多样性，并发布了一张 DVD。

蛋白A树脂市场-IMG1

预计在预测期内北美将占据很大的市场份额

由于传染病和慢性病负担加重、研究市场的技术进步以及製药和生物研究的研发支出增加等因素，预计北美地区的蛋白 A 树脂市场将保持良好增长.增加。 预计主要市场参与者的产品发布和战略举措也将有助于市场增长。

例如，根据美国癌症协会公布的2022年数据，2021年美国估计将有190万新诊断的癌症患者。 而根据加拿大公共卫生署2021年10月公布的数据，约有五分之二的加拿大人一生中会被诊断出患有癌症，估计2021年将有229,000名加拿大人被诊断出患有癌症。 肺癌、乳腺癌、结直肠癌和前列腺癌仍然是最常诊断的癌症，预计到 2021 年将占所有癌症诊断的约 46%。 北美国家慢性病患病率如此之高，预计将有助于对用于诊断目的和开发适当治疗方法的蛋白 A 树脂的需求，并促进市场增长。

另一方面，各种市场参与者增加产品发布以满足对蛋白 A 树脂不断增长的需求，预计也将促进该地区的市场增长。 例如，2022 年 3 月，Sengenics 宣布了一项自身抗体分析服务——“Pan-Autoimmune Protein Array 1.0”，用于有效识别和量化自身抗体疾病生物标誌物特征。 这是一种基于蛋白质微阵列的多重免疫测定，利用 Sengenics 的 KREX 蛋白质折迭技术和优化的计算分析。

蛋白A树脂市场-IMG2

蛋白A树脂行业概况

蛋白 A 树脂市场由全球参与者主导，竞争适中。 公司正在采取措施增加其在蛋白 A 树脂市场的影响力。 预计将主导蛋白 A 树脂市场的主要参与者是 Thermofisher Scientific Inc.、GE Healthcare、Merck KGaA、Agarose Beads Technologies、Bio-Rad Laboratories, Inc、Expedon Ltd.、Genscript Corporation、Novasep、Purolite Lifescience、Repligen。

其他福利：

  • Excel 格式的市场预测 (ME) 表
  • 3 个月的分析师支持

内容

第一章介绍

  • 调查假设和市场定义
  • 本次调查的范围

第二章研究方法论

第 3 章执行摘要

第四章市场动态

  • 市场概览
  • 市场驱动力
    • 抗体需求增加
    • 启动药物发现和研发活动
  • 市场製约因素
    • 蛋白 A 树脂成本高
  • 波特的五力分析
    • 新进入者的威胁
    • 买方/消费者议价能力
    • 供应商的议价能力
    • 替代品的威胁
    • 竞争公司之间的敌对关係

第 5 章市场细分（市场规模、价值）

  • 按产品分类
    • 基于琼脂糖的蛋白质
    • 基于玻璃或二氧化硅的蛋白质
    • 基于有机聚合物的蛋白质
  • 通过使用
    • 抗体纯化
    • 免疫沉淀
  • 最终用户
    • 製药和生物製药公司
    • 研究机构等
    • 其他最终用户
  • 按地区
    • 北美
      • 美国
      • 加拿大
      • 墨西哥
    • 欧洲
      • 德国
      • 英国
      • 法国
      • 意大利
      • 西班牙
      • 其他欧洲
    • 亚太地区
      • 中国
      • 日本
      • 印度
      • 澳大利亚
      • 韩国
      • 其他亚太地区
    • 中东和非洲
      • 海湾合作委员会
      • 南非
      • 其他中东和非洲地区
    • 南美洲
      • 巴西
      • 阿根廷
      • 其他南美洲

第6章竞争格局

  • 公司简介
    • Agarose Beads Technologies
    • Bio-Rad Laboratories, Inc.
    • Expedeon Ltd.
    • GE Healthcare
    • Genscript Corporation
    • Merck KGaA
    • Novasep
    • Purolite Lifesciences
    • Repligen
    • Thermofisher Scientific Inc.
    • Tosoh Bioscience
    • Kaneka Corporation
    • JSR Life Sciences

第7章 市场机会与将来动向

简介目录
Product Code: 71811

The protein A resin market is expected to register a CAGR of around 8.5% over the forecast period.

The emergence of the COVID-19 disease had a notable impact on the growth of the market over the pandemic period. This sudden outbreak led to unprecedented demand for effective diagnostics and highly safe manufacturing of COVID-19 therapeutics. Such circumstances have lured the market players to adopt protein A resin in the manufacture of COVID-19 vaccines, thereby impacting the market growth. For instance, in February 2021, Prepligen collaborated with Navigo Proteins and developed a unique purification resin, NGL COVID-19 Spike Protein Affinity Resin. The resin is used to purify COVID-19 vaccines and is used in binding to the SARS-CoV-2 spike protein binding to the receptor binding domain. Thus, these developments have had a crucial impact on the growth of the market over the pandemic period. In addition, the demand for protein A resin is expected to remain intact due to the emergence of mutant strains of the SARS-CoV-2 virus, thereby contributing to the growth of the market over the forecast period.

The growth of the protein A resin market is majorly attributed to the increasing burden of chronic diseases across the globe and the rising demand for therapeutics for antibodies in order to treat chronic disorders. Additionally, the efficacy of protein A-resin in the diagnosis of various chronic diseases is also expected to boost the growth of the market. For instance, an NCBI article published in May 2021, mentioned that a low-cost thermophoretic aptasensor (TAS) is used to profile cancer-associated protein profiles of plasma EVs without the interference of soluble proteins. This demonstrated that protein analysis has a high accuracy of 91.1% for discrimination of metastatic breast cancer, non-metastatic breast cancer, and healthy donors (HD). Thus, studies proving the efficiency of protein A resin in cancer diagnosis are expected to contribute to the growth of the market.

Additionally, the rising burden of chronic diseases is also expected to contribute to the growth of the market. For instance, as per a WHO factsheet published in February 2022, in 2021, there were an estimated 1.9 million new cancer cases diagnosed in the United States. The report also mentioned that each year, approximately 400,000 children develop cancer globally. Cervical cancer is the most common in 23 countries such as Eswatini, India, South Africa, Latin America, and others. The most common cancers are breast, lung, colon and rectum, and prostate cancers.

While several factors contribute to the growth of the market, the high cost associated with protein A-resin is expected to impede the growth of the market over the forecast period.

Protein A Resin Market Trends

Pharmaceutical and Biopharmaceutical Companies are Expected to Dominate the End User Segment

Pharmaceutical and biopharmaceutical companies mainly use proteins as the principal target, and thus, protein analysis has a very important role in drug discovery and development in the pharma and biotech industries. The common application of protein analysis involves target identification, evaluation, identification of efficacy and toxicity biomarkers from readily accessible biological fluids, and investigations into mechanisms of drug action or toxicity, among others, which in turn is expected to grow significantly due to a large number of ongoing drug development projects in the pharmaceutical and biopharmaceutical projects across the world.

A rise in government funding for pharmaceutical research and development and technological advancements in the area of analytical instruments are expected to drive the growth of the studied segment. Also, increasing life science R&D expenditure, progressing drug discovery, and an increase in the adoption of chromatography are key factors driving the growth of the protein A resins market in the pharmaceutical and biopharmaceutical industries. For instance, the data published by EFPIA in 2022 mentioned that the research and development expenditure of the pharmaceutical industry in Europe in 2021 was EUR 41.5 million (USD 44.6 million). Such high pharmaceutical expenditures are expected to drive the demand for protein A resin in drug development research and the development of various diagnostic tests, thereby boosting the growth of the studied segment.

Additionally, increasing product launches in order to address the demand from the pharmaceutical and biopharmaceutical industries are also expected to contribute to the growth of the market. For instance, in September 2021, Purolite launched two novel next-generation chromatography resins, Praesto Jetted A50 HipH, and Praesto Jetted dt 18-DVD to address the diversity of biomolecule pipelines of antibodies, vaccines, and gene therapy.

Protein A Resin Market - IMG1

North America is Expected to Hold a Significant Share in the Market Over the Forecast Period

The market for protein A resin in the North American region is expected to experience lucrative growth owing to the factors such as the rising burden of infectious and chronic diseases, technological advancements in the studied market, and increasing research and development expenditure on pharmaceutical and biological research. In addition, the product launches and strategic initiatives by key market players will also contribute to the market growth.

For instance, according to the American Cancer Society Inc., data published in 2022, in 2021, there were an estimated 1.9 million new cancer cases diagnosed in the United States. In addition, according to the Public Health Agency of Canada data published in October 2021, approximately 2 in 5 Canadians were diagnosed with cancer in their lifetime, and in 2021, an estimated 229,000 Canadians were diagnosed with cancer. The report also mentioned that lung, breast, colorectal, and prostate cancers were expected to remain the most commonly diagnosed cancers, accounting for nearly 46% of all cancer diagnoses in 2021. Such a high prevalence of chronic diseases in North American countries is expected to contribute to the demand for protein A resin for diagnostic purposes and the development of appropriate therapies, thereby boosting the market growth.

On the other hand, the rising product launches by various market players to meet the growing demand for protein A resin is also expected to fuel the market growth in this region. For instance, in March 2022, Sengenics launched an autoantibody profiling service - the 'Pan-Autoimmune Protein Array 1.0' for efficient identification and quantitation of autoantibody disease biomarker signatures. It is a protein microarray-based, multiplexed immunoassay which utilizes Sengenics' KREX protein folding technology and optimized computational analysis.

Protein A Resin Market - IMG2

Protein A Resin Industry Overview

The protein A resin market is moderately competitive, with a presence of mostly global companies. Companies are taking the initiative to grow their presence in the Protein A Resin market. Key players expected to dominate the Protein A Resin market are Thermofisher Scientific Inc., GE Healthcare, Merck KGaA, Agarose Beads Technologies, Bio-Rad Laboratories, Inc., Expedeon Ltd., Genscript Corporation, Novasep, Purolite Lifescience, and Repligen.

Additional Benefits:

  • The market estimate (ME) sheet in Excel format
  • 3 months of analyst support

TABLE OF CONTENTS

1 INTRODUCTION

  • 1.1 Study Assumptions and Market Definition
  • 1.2 Scope of the Study

2 RESEARCH METHODOLOGY

3 EXECUTIVE SUMMARY

4 MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Increasing Demand for Antibodies
    • 4.2.2 Increasing Number of Drug Discoveries and R&D Activities
  • 4.3 Market Restraints
    • 4.3.1 High Cost Associated With Protein A Resin
  • 4.4 Porter's Five Forces Analysis
    • 4.4.1 Threat of New Entrants
    • 4.4.2 Bargaining Power of Buyers/Consumers
    • 4.4.3 Bargaining Power of Suppliers
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5 MARKET SEGMENTATION (Market Size - Value in USD million)

  • 5.1 By Product
    • 5.1.1 Agarose -based Protein
    • 5.1.2 Glass or Silica-based Protein
    • 5.1.3 Organic Polymer-based Protein
  • 5.2 By Application
    • 5.2.1 Antibody Purification
    • 5.2.2 Immunoprecipitation
  • 5.3 By End User
    • 5.3.1 Pharmaceutical & Biopharmaceutical Companies
    • 5.3.2 Research Laboratories
    • 5.3.3 Other End Users
  • 5.4 Geography
    • 5.4.1 North America
      • 5.4.1.1 United States
      • 5.4.1.2 Canada
      • 5.4.1.3 Mexico
    • 5.4.2 Europe
      • 5.4.2.1 Germany
      • 5.4.2.2 United Kingdom
      • 5.4.2.3 France
      • 5.4.2.4 Italy
      • 5.4.2.5 Spain
      • 5.4.2.6 Rest of Europe
    • 5.4.3 Asia-Pacific
      • 5.4.3.1 China
      • 5.4.3.2 Japan
      • 5.4.3.3 India
      • 5.4.3.4 Australia
      • 5.4.3.5 South Korea
      • 5.4.3.6 Rest of Asia-Pacific
    • 5.4.4 Middle East and Africa
      • 5.4.4.1 GCC
      • 5.4.4.2 South Africa
      • 5.4.4.3 Rest of Middle East and Africa
    • 5.4.5 South America
      • 5.4.5.1 Brazil
      • 5.4.5.2 Argentina
      • 5.4.5.3 Rest of South America

6 COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 Agarose Beads Technologies
    • 6.1.2 Bio-Rad Laboratories, Inc.
    • 6.1.3 Expedeon Ltd.
    • 6.1.4 GE Healthcare
    • 6.1.5 Genscript Corporation
    • 6.1.6 Merck KGaA
    • 6.1.7 Novasep
    • 6.1.8 Purolite Lifesciences
    • 6.1.9 Repligen
    • 6.1.10 Thermofisher Scientific Inc.
    • 6.1.11 Tosoh Bioscience
    • 6.1.12 Kaneka Corporation
    • 6.1.13 JSR Life Sciences

7 MARKET OPPORTUNITIES AND FUTURE TRENDS