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市场调查报告书
商品编码
1407029

製药喷雾干燥：市场占有率分析、产业趋势/统计、成长预测（2024-2029）

Pharmaceutical Spray Drying - Market Share Analysis, Industry Trends & Statistics, Growth Forecasts 2024 - 2029
出版日期: | 出版商: Mordor Intelligence | 英文 123 Pages | 商品交期: 2-3个工作天内

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简介目录

预计2024年全球药品喷雾干燥市场规模将达19.7亿美元，2024-2029年预测期间复合年增长率为7.13%，2029年将达27.8亿美元。

医药喷雾干燥-市场-IMG1

主要亮点

  • 由于製造流程显着放缓以及药品供需有限，疫情的初始阶段对药品喷雾干燥市场的成长产生了重大影响。多个国家的政府报告称，由于 COVID-19 大流行，活性药物成分出现短缺。同样，根据药品出口促进委员会（PHARMEXCIL）的数据，2021年，COVID-19大流行将增加对治疗爱滋病毒、癌症、癫痫和疟疾等各种疾病的药物的需求，从而显着提高药品急剧上升。然而，药物短缺的恢復以及 COVID-19 药物、製药应用和疫苗越来越多地使用药物喷雾干燥正在对市场产生积极影响。例如，根据2023 年2 月发表的一项题为“喷雾冻干氯硝柳胺奈米晶体嵌入干粉用于高肺部剂量输送”的研究，氯硝柳胺（NCL）已显示出在治疗COVID- 19 方面的应用潜力。然而，开发有效的氯硝柳胺（NCL）递送新製剂仍然是一项挑战。在这种情况下，采用新型喷雾冷冻干燥技术生产了含氯硝柳胺的吸入用干粉剂（NeDPI），使药物输送更容易。此类案例表明，由于供应链中断，市场成长最初放缓。然而，随着供不应求的恢復以及 COVID-19 药物和疫苗的药物喷雾干燥利用率的增加，市场在大流行期间受到积极影响，预计在预测期内将继续呈上升趋势。
  • 慢性病盛行率增加、技术进步、产品稳定性提高以及研发费用增加是推动市场成长的主要因素。药品研发投入增加，采用不同的商业策略，先进的技术，以及喷雾干燥方法的优势，如干燥速度快、适应性强、与热敏材料相容、易于保持产品品质等。製药业越来越多地采用喷雾干燥方法，从而推动了预测期内的市场成长。根据 PharmTech 2022 年 2 月发表的学术期刊报道，生物製药药物开发的增加导致可以替代传统液体和冷冻干燥固态的生物製药的增加。干燥正在增加。新的药物喷雾干燥方法可以显着控制所生产粉末的特性，从而提供显着的下游加工优势。透过适当的製程开发，喷雾干燥还可以直接压缩无定形固体分散体 (ASD) 製剂，从而避免压片前造粒的需要。由于这些技术进步，大多数製药公司更喜欢喷雾干燥而不是传统方法。
  • 此外，慢性病的增加也推动了市场的成长。例如，根据国际糖尿病联盟2021年发布的资料，约有5.37亿成年人患有糖尿病，预计2030年约有6.43亿人患有糖尿病。另据报导，四分之三的成年人患有糖尿病，二分之一的成年人（2.4 亿人）患有未确诊的糖尿病。同样，根据国际糖尿病联盟 2021 年发布的报告，超过 120 万名青少年和儿童患有第 1 型糖尿病。此外，根据 2023 年美国癌症协会大肠直肠癌统计数据，预计 2023 年美国将有超过 153,020 名成年人被诊断出患有大肠肠癌。这些数字包括美国106,970 例结肠癌新病例和 46,050 例直肠癌新病例。因为製药喷雾干燥是大多数製药公司生产高品质药品的首选技术。慢性疾病患者数量的增加预计将推动对高品质治疗药物开发的需求，这可能会推动对喷雾干燥技术的需求。因此，慢性病的高盛行率预计将对预测期内的市场成长产生积极影响。
  • 然而，喷雾干燥相关的高成本以及对经验丰富的操作员的需求可能会阻碍预测期内的市场成长。

医药喷雾干燥市场趋势

预计辅料製造领域在预测期内将大幅成长

  • 药用辅料是活性药物成分 (API) 以外的物质，经过适当的安全性评估，并有意包含在药物传输系统中。透过喷雾干燥法生产干燥颗粒包括将赋形剂溶解在水性或有机溶剂中，然后在高于溶剂汽化点的温度下使用高压空气透过细雾化喷嘴将所得溶液雾化而完成。由此释放的微小液滴被快速干燥，然后透过旋风机构收集。颗粒尺寸由溶液中赋形剂的浓度和施加到气流的压力控制。
  • 辅料的优势和不断增加的研究是市场的主要驱动因素。赋形剂能够实现药物输送，对药物製剂至关重要，有时占药物製剂的 80-90%。对于品牌药物，使用新型赋形剂可以优化药物性能和格式，开发以前未开发的候选药物，并提供优化患者格式的创新药物。因此，考虑到这些分子的优势，製药公司正在对这些赋形剂的生产进行巨额投资。因此，喷雾干燥的使用越来越多地用于特殊製造，从而导致该领域的成长。
  • 此外，不断增加的研究工作预计也将推动该领域的成长。例如，2021 年 9 月，美国食品药物管理局(USFDA) 启动了一项新的试验计画，审查用于满足新药物配方中未满足需求的新型辅料。透过该计划，FDA 打算加速辅料的开发，这些辅料可能在辅料製造商和药物开发商之前提到使用现有辅料存在困难的情况下有用。政府的此类倡议预计将在预测期内支持该行业的成长。
  • 此外，药品需求的增加、辅料製造设备的新投资以及政府促进药品和其他药品国内生产的措施预计将在预测期内推动市场成长。例如，2023 年 6 月，Croda, Inc. 开始在宾州建造一座新工厂，以扩大其药用辅料製造能力。据该公司称，新工厂将生产用于 mRNA 疫苗和基因编辑疗法等新型疗法的药物传输系统的原料。因此，新的赋形剂生产设施的推出预计将增加对喷雾干燥的需求，因为它是赋形剂生产的重要组成部分之一。
  • 因此，由于喷雾干燥技术在辅料製造中的重要性非常高，因此该技术提供的优势和不断增加的辅料製造设施数量预计将在预测期内推动该领域的成长。
医药喷雾干燥-市场-IMG2

预计北美将在预测期内占据最大份额

  • 由于大型製药企业的存在、药品需求量大、技术先进、医药品研究开发费用高等因素，北美预计将占较大比例。越来越多的公司专注于市场扩张并采取业务策略来维持其市场地位，预计这将支持市场成长。
  • 例如，2022年1月，Eurofins（合约开发和製造组织）宣布扩大其在北美现有的喷雾干燥开发和製造服务。此次扩张使 Eurofins 能够进一步补充其致力于提高临床开发和小型商业项目溶解度的广泛服务。
  • 慢性病负担的增加以及对药物研发活动的投资增加是预计在预测期内推动该地区药物喷雾干燥市场的一些主要驱动因素。例如，根据美国癌症协会2022年报告，2022年日本将报告约190万癌症病例，其中乳癌是最常见的癌症型态。
  • 此外，随着对干燥药品的需求不断增加，该公司正在获取先进的喷雾干燥技术以提高生产和工作流程。预计此类收购将在预测期内进一步推动美国市场的成长。
  • 例如，2023年5月，服务于生物製药行业的合约开发和受託製造厂商（CDMO）和临床试验供应服务公司Experic宣布推出其喷雾干燥能力，以支援生物製药配方和开发，并宣布新增功能。
  • 因此，由于慢性病的高盛行率和对原料药生产设施的投资，预计在预测期内北美的药品喷雾干燥市场将会成长。

製药喷雾干燥产业概述

由于不同参与者的存在，药品喷雾干燥市场变得分散。主导市场的一些参与者包括山东天利干燥设备有限公司、Buchi Labortecknik AG、European SprayDry Technologies 和 Labplant UK。

其他福利

  • Excel 格式的市场预测 (ME) 表
  • 3 个月分析师支持

目录

第一章简介

  • 研究假设和市场定义
  • 调查范围

第二章调查方法

第三章执行摘要

第四章市场动态

  • 市场概况
  • 市场驱动因素
    • 慢性病盛行率增加
    • 技术进步和产品稳定性提高
    • 研发费用增加
  • 市场抑制因素
    • 与喷雾干燥相关的高成本且需要熟练的操作人员
  • 波特五力分析
    • 新进入者的威胁
    • 买家/消费者的议价能力
    • 供应商的议价能力
    • 替代品的威胁
    • 竞争公司之间的敌对关係

第五章市场区隔－市场规模：按金额（美元）

  • 按用途
    • 辅料製造
    • 封装
    • 提高生物有效性
    • 其他用途
  • 按地区
    • 北美洲
      • 美国
      • 加拿大
      • 墨西哥
    • 欧洲
      • 德国
      • 英国
      • 法国
      • 义大利
      • 西班牙
      • 欧洲其他地区
    • 亚太地区
      • 中国
      • 日本
      • 印度
      • 澳洲
      • 韩国
      • 其他亚太地区
    • 中东/非洲
      • GCC
      • 南非
      • 其他中东/非洲
    • 南美洲
      • 巴西
      • 阿根廷
      • 南美洲其他地区

第六章 竞争形势

  • 公司简介
    • GEA Group Aktiengesellschaft
    • SPX Flow
    • Hovione
    • Shandong Tianli Drying Equipment Corporation Ltd.
    • Buchi Labortecknik AG
    • European SprayDry Technologies
    • Labplant UK
    • New AVM Systech Pvt. Ltd.
    • Advanced Drying Systems
    • Lemar Drying Engineering

第七章 市场机会及未来趋势

简介目录
Product Code: 90725
Pharmaceutical Spray Drying - Market - IMG1

The pharmaceutical spray drying market size is expected to grow from USD 1.97 billion in 2024 to USD 2.78 billion by 2029, at a CAGR of 7.13% during the forecast period (2024-2029).

Key Highlights

  • The initial phase of the pandemic has had a substantial impact on the growth of the pharmaceutical spray drying market owing to the significant decline in manufacturing processes and restricted demand and supply of drugs. The government of several countries has reported that active pharmaceutical ingredients are in short supply because of the COVID-19 pandemic. Likewise, according to the Pharmaceutical Export Promotion Council (PHARMEXCIL), in 2021, the COVID-19 pandemic resulted in a massive spike in medicine prices due to increased demand for drugs to treat a variety of diseases, including HIV, cancer, epilepsy, and malaria. However, the recovery from the shortage and increasing use of pharmaceutical spray drying for COVID-19 drugs, drug applications, and vaccines have positively impacted the market. For instance, according to the study titled, 'Spray freeze-dried niclosamidenanocrystals embedded dry powder for high dose pulmonary delivery,' published in February 2023, niclosamide(NCL) has shown potential applications for treating COVID-19. However, the development of new formulations for effective niclosamide(NCL) delivery is still challenging. In such cases, niclosamide-embedded dry powder for inhalation (NeDPI) was fabricated by a novel spray freeze-drying technology, making it easier for drug delivery. Therefore, such instances indicate that the market initially witnessed slow growth owing to supply chain disruption. However, with the recovery from shortage and increasing use of pharmaceutical spray drying for COVID-19 drugs and vaccines, the market witnessed a positive impact during the pandemic and is expected to continue the upward trend over the forecast period.
  • The increasing prevalence of chronic diseases, technological advancements, improvements in the stability of products, and increasing research and development spending are the major factors propelling market growth. With the increasing pharmaceutical spending on research and development, adoption of various business strategies, and advanced technology, and the advantages offered by the spray drying methods, such as quick-drying, adaptability, compatibility with heat-sensitive materials, and ease of product quality maintenance, spray drying methods are being increasingly adopted in the pharmaceutical industry, boosting market growth over the forecast period. According to the journal published in February 2022 by PharmTech, the increased development of biologic-based drugs has fueled the demand for spray drying as an alternative for the manufacturing and processing of biologics instead of the more traditional liquid or lyophilized solid forms. The new pharmaceutical spray drying methods offer remarkable control over the properties of the manufactured powders, with significant downstream advantages. With adequate process development, spray drying can also enable amorphous solid dispersion (ASDs) formulations that are directly compressible, thus bypassing the need for granulation prior to tableting. Thus, owing to such technological advancements, the majority of pharmaceutical companies are adopting spray drying over traditional methods.
  • In addition, increasing cases of chronic diseases are also propelling market growth. For instance, according to the data published by the International Diabetes Federation in 2021, around 537.0 million adults are living with diabetes, and by 2030, around 643.0 million people are expected to live with diabetes. It also reported that 3 out of 4 adults live with diabetes, and around 1 out of 2 adults (240.0 million) are living with undiagnosed diabetes. Similarly, according to the report published by the International Diabetes Federation in 2021, more than 1.2 million adolescents and children are living with type 1 diabetes. Furthermore, according to the American Cancer Society Colorectal Cancer Statistics in 2023, over 153,020 adults are estimated to be diagnosed with colorectal cancer in 2023 in the United States. These numbers include 106,970 new cases of colon cancer and 46,050 new cases of rectal cancer in the United States, as pharmaceutical spray drying is a technique preferred by most pharmaceutical companies to produce quality drugs. Increasing cases of chronic diseases are anticipated to boost the demand for quality drug development for treatment, which in turn may boost the demand for spray-drying techniques. Thus, the high prevalence of chronic diseases is expected to positively impact the market growth over the forecast period.
  • However, the high cost associated with spray drying and the requirement of experienced operators is likely to hinder the market growth over the forecast period.

Pharmaceutical Spray Drying Market Trends

Excipient Production Segment is Expected to Witness Considerable Growth Over the Forecast Period

  • Pharmaceutical excipients are substances other than the active pharmaceutical ingredient (API) that have been appropriately evaluated for safety and are intentionally included in a drug delivery system. Manufacturing dry particles by the spray-drying method proceeds in such a way that excipients are dissolved in aqueous or organic solvents, after which the solution thus obtained is sprayed through a narrow atomization nozzle with high pressurized air at a temperature higher than the vaporization point of the solvent. The fine droplets thus emitted are quickly dried, followed by a collection of particles generated by a cyclone mechanism. The particle size is regulated by the concentration of excipients in the solution and the pressure given to the airflow.
  • The advantages of excipients and increasing research work are the major drivers for the market. Excipients are essential to the formulation of drug products because they enable the effective delivery of drug substances and can account for as much as 80-90% of the drug product formulation. For branded drugs, novel excipients could be used to optimize drug product performance and presentation and possibly develop candidates that were deemed undevelopable, leading to transformative medicines with optimized patient presentations. Hence, considering the advantages of these molecules, pharmaceutical companies are investing huge amounts in manufacturing these excipients; therefore, there is increasing use of spray drying for the exception production, posting the segment growth.
  • In addition, increasing research work is also anticipated to propel the segment growth. For instance, in September 2021, the UInted States Food and Drug Administration (USFDA launched a new pilot program to review novel excipients for use in meeting unmet needs in formulating new drug products. Through this program, the FDA intends to raise the development of excipients that may be useful in scenarios where excipient manufacturers and drug developers have cited prior difficulty in using existing excipients. Such initiatives by the government are expected to boost segment growth over the forecast period.
  • Additionally, the rising demand for pharmaceuticals, new investments in the facilities for excipient production, and government initiatives to promote domestic manufacturing of drugs and other pharmaceutical products are expected to boost the market's growth over the forecast period. For instance, in June 2023, Croda, Inc. started constructing its new Pennsylvania facility to enhance its pharmaceutical excipients manufacturing capacity. As per the company, the new facility will be involved in manufacturing ingredients for drug delivery systems used in novel therapeutic drugs such as mRNA vaccines and gene editing therapies. Hence, the launch of new excipient manufacturing facilities is expected to boost the demand for spray dryers as they are one of the essential components for excipient production.
  • Therefore, owing to the enormous significance of the spray drying technique in excipient production, the advantages offered by this technique and an increasing number of excipient manufacturing facilities are expected to boost segment growth over the forecast period.
Pharmaceutical Spray Drying - Market - IMG2

North America is Expected to held Largest Share Over the Forecast Period

  • North America is anticipated to have a significant share owing to factors such as the presence of major pharmaceutical players, high demand for pharmaceutical products, technological advancement, and high pharmaceutical research and development expenditure in the region. The increasing company focus on expansion and adopting business strategies to withhold their position in the market is likely to boost the growth of the market.
  • For instance, in January 2022, Eurofins (Contract Development and Manufacturing Organization) announced the expansion of its existing spray dry development and production services in North America. With this expansion, Eurofins can further complement a broad range of services specializing in solubility enhancement for clinical development and small-scale commercial programs.
  • The increasing burden of chronic diseases and increasing investment in pharmaceutical research and development activities are some of the major driving factors that are expected to drive the pharmaceutical spray drying market in the region over the forecast period. For instance, according to the 2022 report of the American Cancer Society, about 1.9 million cases of cancer were reported in the country in 2022, with breast cancer being the most prevalent form of cancer.
  • Moreover, with the rising demand for dried pharmaceutical products, companies are acquiring advanced spray-drying technologies to enhance their production and workflow. Such acquisitions are further expected to boost the market's growth in the United States over the forecast period.
  • For instance, in May 2023, Experic, a contract development and manufacturing organization (CDMO) and clinical trial supply services company serving the biopharmaceutical industry, announced the addition of spray drying capabilities to support the formulation and development of biopharmaceuticals.
  • Therefore, owing to the high prevalence of chronic diseases and investment in active pharmaceutical ingredient manufacturing facilities, the pharmaceutical spray drying market is expected to grow in North America over the forecast period.

Pharmaceutical Spray Drying Industry Overview

The pharmaceutical spray drying market is fragmented due to the presence of various players in the market. Some of the players who are dominating the market are Shandong Tianli Drying Equipment Corporation Ltd, Buchi Labortecknik AG, European SprayDry Technologies, and Labplant UK, among others.

Additional Benefits:

  • The market estimate (ME) sheet in Excel format
  • 3 months of analyst support

TABLE OF CONTENTS

1 INTRODUCTION

  • 1.1 Study Assumptions and Market Definition
  • 1.2 Scope of the Study

2 RESEARCH METHODOLOGY

3 EXECUTIVE SUMMARY

4 MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Increasing Prevalence of Chronic Diseases
    • 4.2.2 Technological Advancements and Improvements in the Stability of Products
    • 4.2.3 Increasing Research and Development Spending
  • 4.3 Market Restraints
    • 4.3.1 High Cost Associated with Spray Drying and Requirement of Experienced Operators
  • 4.4 Porter's Five Forces Analysis
    • 4.4.1 Threat of New Entrants
    • 4.4.2 Bargaining Power of Buyers/Consumers
    • 4.4.3 Bargaining Power of Suppliers
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5 MARKET SEGMENTATION (Market Size by Value - USD)

  • 5.1 By Application
    • 5.1.1 Excipient Production
    • 5.1.2 Encapsulation
    • 5.1.3 Enhancing Bioavailability
    • 5.1.4 Other Applications
  • 5.2 Geography
    • 5.2.1 North America
      • 5.2.1.1 United States
      • 5.2.1.2 Canada
      • 5.2.1.3 Mexico
    • 5.2.2 Europe
      • 5.2.2.1 Germany
      • 5.2.2.2 United Kingdom
      • 5.2.2.3 France
      • 5.2.2.4 Italy
      • 5.2.2.5 Spain
      • 5.2.2.6 Rest of Europe
    • 5.2.3 Asia-Pacific
      • 5.2.3.1 China
      • 5.2.3.2 Japan
      • 5.2.3.3 India
      • 5.2.3.4 Australia
      • 5.2.3.5 South Korea
      • 5.2.3.6 Rest of Asia-Pacific
    • 5.2.4 Middle East and Africa
      • 5.2.4.1 GCC
      • 5.2.4.2 South Africa
      • 5.2.4.3 Rest of Middle East and Africa
    • 5.2.5 South America
      • 5.2.5.1 Brazil
      • 5.2.5.2 Argentina
      • 5.2.5.3 Rest of South America

6 COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 GEA Group Aktiengesellschaft
    • 6.1.2 SPX Flow
    • 6.1.3 Hovione
    • 6.1.4 Shandong Tianli Drying Equipment Corporation Ltd.
    • 6.1.5 Buchi Labortecknik AG
    • 6.1.6 European SprayDry Technologies
    • 6.1.7 Labplant UK
    • 6.1.8 New AVM Systech Pvt. Ltd.
    • 6.1.9 Advanced Drying Systems
    • 6.1.10 Lemar Drying Engineering

7 MARKET OPPORTUNITIES AND FUTURE TRENDS