市场调查报告书
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1408047
全球重组蛋白市场评估:按产品、宿主细胞、应用、最终用户、地区、机会、预测(2017-2031)Recombinant Proteins Market Assessment, By Product, By Host Cell, By Application, By End-user, By Region, Opportunities and Forecast, 2017-2031F |
全球重组蛋白市场规模预计到2023年将达到25.1亿美元,到2031年将达到64.7亿美元,在2024-2031年预测期内复合年增长率为12.57%。 诊断和探索性研究领域的市场取得了显着成长。 近年来到期的生物製品专利数量不断增加,推动了市场需求。 预计 2022 年至 2027 年间,约 31 种生物製剂将失去独占权,创造庞大的市场需求。
生物技术领域不断增加的研发支出正在推动全球重组蛋白市场的显着成长。 由于重组蛋白在医疗、研究和生技领域的应用不断扩大,预计在预测期内对重组蛋白产品的需求将会增加。 此外,癌症、自体免疫疾病和糖尿病等慢性病的盛行率不断上升,需要生物製剂治疗,约占生物製剂市场的60%,重组蛋白市场的需求不断增加,预计将吸引100%的公司。 然而,重组蛋白生产的特殊要求和产品的高成本是市场的限制因素。
越来越多的生物製品专利到期正在推动重组蛋白市场的成长。 生物製剂是由活细胞製成的复杂分子,用于治疗多种疾病,包括癌症、自体免疫疾病和慢性肾臟病。 多个重磅生物製剂的专利已经到期或计划到期,推动了生物相似药和生物相似药的发展。 这些专利的到期为生物相似药和生物后续产品的开发创造了机会,推动了市场成长。
研发支出的增加对重组蛋白市场产生了重大影响。 增加的投资正在促进创新蛋白质体学和基因组学技术的发展,并促进重组蛋白的生产。 预计亚太地区研发活动的增加尤其明显,为市场进入者提供潜在的成长机会。 研发支出的快速成长是市场扩张的关键驱动力。
由于细胞激素和生长因子在癌症、COVID-19、细胞培养、传染病和伤口癒合研究中发挥重要作用,因此预计将占据主导地位。 慢性病盛行率的增加和治疗需求的增加增加了对重组蛋白产品的需求。 对这些因子的研究和开发正在推动细胞因子和生长因子领域的主导地位。
北美主导全球重组蛋白市场。 2022 年,北美将占据大部分收入份额,并预计未来将保持这一地位。 该地区的优势在于政府为製药业的研发提供资助策略、增加研发项目以及有利的政府资助。 美国占北美市场最大份额。 公司之间日益激烈的竞争和最终用户的多样化使用正在促进产品管道的扩展、新技术的开发和生物加工工具的进步。
全球重组蛋白市场前景广阔,预计未来几年将显着成长。 市场驱动因素包括慢性病盛行率上升、研究和学术领域越来越多地采用生命科学和技术,以及领先的製药和生物技术公司的大量存在。 由于研究活动、新产品开发和最终用户采用率的增加,亚太地区预计将显着成长。 预计该市场将由细胞激素、生长因子、抗体和免疫检查点蛋白等产品主导。 该市场的主要参与者包括 Thermo Fisher Scientific, Inc.(美国)、R&D Systems(美国)、Abcam plc(英国)和 Merck KGaA(德国)。 除了医学之外,重组蛋白还用于农业、食品生产和生物工程,预计在不久的将来需求将进一步增加。
本报告研究和分析了全球重组蛋白市场,提供市场规模和预测、市场动态、主要参与者现状和前景等。
Global Recombinant Proteins market size was valued at USD 2.51 billion in 2023, and is expected to reach USD 6.47 billion in 2031, with a CAGR of 12.57% for the forecast period between 2024 and 2031F. The recombinant protein market has registered significant growth in the field of diagnostic and exploratory research. The increase in the number of biologics patents expiring recently is driving demand for the recombinant protein market. About 31 biologics will lose exclusivity between 2022 and 2027 which is expected to create huge demand in the market.
Increasing expenditure on research and development in the field of biotechnology is promoting significant growth in the global recombinant proteins market. Due to the expansion of applications of recombinant proteins in the domain of medicine, research, and biotechnology, the demand for recombinant protein products is expected to increase during the forecast period. Additionally, the growing prevalence of chronic diseases like cancer, auto-immune diseases, and diabetes require biologics for treatment and contribute to about 60% of the biologics market, which is expected to draw more business in the recombinant proteins market. However, specific requirements of recombinant protein production and high cost of products are some of the factors restraining recombinant proteins market.
For instance, in June 2022, Navigo Proteins GmbH, a leading provider of affinity ligands for customized chromatography solutions and protein engineering, developed an affinity resin to capture the glycoprotein gp64, an unwanted contaminant from the baculovirus insect cell production system. By effectively utilizing precision capturing technology, Navigo was able to create a Precision X ligand that binds to the gp64 contaminant.
The increasing number of biologics patent expiry is driving the growth of the recombinant proteins market. Biologics are complex molecules produced from living cells and are used to treat various diseases such as cancer, autoimmune diseases, and chronic kidney disease. Patents for several blockbuster biologics have expired or are set to expire, leading to the development of biosimilars and follow-on biologics. The expiration of these patents has created opportunities for the development of biosimilars and follow-on biologics, which are driving the growth of the recombinant proteins market.
According to The Center for Biosimilar, by 2023, patents on nearly 20 oncology biologics will expire. The highest-earning drug, Humira is losing exclusivity in the year 2023, opening a huge opportunity for the biosimilar market. Johnson & Johnson's Stelara is going off-patent in the second half of 2023 which is a promising candidate for the biosimilar market.
The increasing expenditure on research and development is significantly impacting the recombinant proteins market. The heightened investment is driving the development of innovative proteomic and genomic techniques, thereby fostering the production of recombinant proteins. The growing R&D initiatives are particularly notable in Asia-Pacific, which is expected to offer potential growth opportunities for market players. The surge in research and development spending is a key driver propelling the expansion of the recombinant proteins market. In February 2023, in a seed extension round, Canadian startup Future Fields secured USD 11.2 million to expand the use of fruit flies as high-value recombinant protein production machines. The firm aims to produce recombinant proteins at a large scale in 10,000 square feet of manufacturing space.
The cytokines and growth factors segment is expected to dominate due to its vast role in research in cancer, COVID-19, cell culture, infectious diseases, and wound healing. The increasing prevalence of chronic diseases and their growing treatment requirements has led to an increase in demand for recombinant protein products. Research and development around these factors are propelling the dominance of cytokines and growth factors segment. In September 2023, Sino Biological, Inc. launched several products for biological research including four high-quality recombinant cytokines and GMP grade cytokines.
North America dominates the global recombinant proteins market. In 2022, North America accounted for a significant portion of the revenue share, and it is expected to maintain its position in the coming years. The region's dominance can be attributed to the availability of funding government initiatives for R&D in the pharmaceutical industry, more R&D programs, and a favorable funding from the government. The United States accounted for the largest share in the North America recombinant proteins market. The growth in competition among players and diverse applications by end-users has contributed to the expansion of product pipelines, the development of new technologies, and the advancement of bioprocessing tools.
The outlook for the global recombinant proteins market appears to be promising, with significant growth expected in the coming years. The market is driven by factors such as the rising prevalence of chronic diseases, the growing adoption of life science techniques in research and academia, and the huge presence of major pharmaceutical and biotechnology companies. Asia-Pacific is projected to witness significant growth due to increasing research activities, new product development, and expanding applications by end-users. The market for recombinant proteins is expected to be dominated by products such as cytokines, growth factors, antibodies, and immune checkpoint proteins. Key players in the recombinant proteins market include Thermo Fisher Scientific, Inc. (US), R&D Systems (US), Abcam plc (UK), Merck KGaA (Germany), and others. Apart from healthcare, recombinant proteins are used in agriculture, food production, and bioengineering, which is further expected to increase demand in the near future.
Market players are expanding their product offerings and giving their customers access to a wide range of cutting-edge and novel products using a variety of strategies. To gain market share, companies are expanding the range of products they offer. Industry participants use a variety of growth methods, including collaborations, mergers and acquisitions, product launches, and the development of new goods, to bolster their position in the market.
In January 2022, Thermo Fisher Scientific Inc. completed the acquisition of PeproTech, Inc. for a total cash purchase price of approximately USD 1.85 billion. PeproTech was a leading manufacturer of recombinant proteins in the United States. The acquisition strengthened the recombinant portfolio of Thermo Fisher Scientific.
All segments will be provided for all regions and countries covered:
Companies mentioned above DO NOT hold any order as per market share and can be changed as per information available during research work.