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市场调查报告书
商品编码
1447728
慢性荨麻疹市场评估:按治疗、诊断、给药途径、最终用户和地区划分的机会和预测(2017-2031)Chronic Spontaneous Urticaria Market Assessment, By Treatment, By Diagnosis, By Route of Administration, By End-user, By Region, Opportunities and Forecast, 2017-2031F |
全球慢性荨麻疹市场规模将从2023年的20.1亿美元增长到2031年的49.5亿美元,2024-2031年预测期间复合年增长率为11.93%。预计将增长至。
多种因素正在推动全球已形成慢性荨麻疹市场。 由于突破性的发现和对该疾病的了解的加深,慢性荨麻疹的全球市场正在显着扩大。
彻底阐明荨麻疹的基本机制有助于开发更强大的治疗药物。 随着製药公司和医疗保健提供者增加研发资金,新的治疗方法也不断被发现并推向市场。 随着对慢性荨麻疹病理生理学的了解不断深入,人们开发出更有效、更有针对性的药物,与传统方法相比,这些药物可以更好地缓解症状。 全球慢性荨麻疹市场也受到皮下给药的影响。 这种方法非常有效,因为它可以让药物完全吸收,而不会影响患者的末梢系统,也不存在损伤血管或神经的可能性。
2023 年 8 月,诺华报告了 III 期 REMIX-1 和 REMIX-2 研究的阳性顶线数据,该研究评估了 BTK 抑制剂瑞布替尼 25 mg b.i.d. 对慢性荨麻疹患者的疗效。 如果获得批准,瑞米布替尼可能成为十年来第一个治疗慢性荨麻疹的药物,为60% 对H1 抗组织胺没有反应的患者提供一种简单而有效的替代方案。
大力投资促进研发
全球慢性荨麻疹市场的成长也得益于製药公司对研发活动的持续关注。 市场主要参与者正在投资数十亿美元的研究工作,以寻找治疗慢性荨麻疹患者的创新解决方案。 透过研究,公司可以深入了解这种疾病治疗的相关因素。
大量投资改善医疗基础建设
鑑于对高效慢性荨麻疹治疗的需求不断增长,全球慢性荨麻疹市场的主要参与者正在加紧努力透过投资改善医疗基础设施。 这种经过深思熟虑的行动是由于慢性荨麻疹发生率上升而引发的。 慢性荨麻疹是一种以无明显原因突然发作的肿胀和荨麻疹为特征的疾病。 透过向医疗基础设施投入更多资金,这些公司希望创造和提供新的、更强大的治疗方法。 除了表现出致力于满足慢性荨麻疹患者未满足的需求之外,这项投资还将显着推动市场发展,因为更好的治疗方法会带来更好的患者结果,并增加对尖端治疗方法的需求。这表明这是可能的。
本报告调查了全球慢性荨麻疹市场,提供市场定义和概述、市场规模趋势和预测、各个细分市场和地区的详细分析、行业结构以及影响市场成长的因素。我们编制分析、案例研究、竞争格局、主要公司简介等等。
The chronic spontaneous urticaria market is projected to witness a CAGR of 11.93% during the forecast period 2024-2031, growing from USD 2.01 billion in 2023 to USD 4.95 billion in 2031. Various factors are shaping the global chronic spontaneous urticaria market such as the increasing prevalence of chronic spontaneous urticaria, significant investments in research and development, availability of suitable medications for treatment, clinical advantages of subcutaneous drugs, and increasing number of clinical trials. The global chronic spontaneous urticaria market, which is defined by recurring hives and angioedema without known triggers, is expanding significantly due to breakthrough discoveries and a better comprehension of the illness.
The creation of more potent treatments is being fueled by a more thorough investigation of the fundamental mechanisms of CSU. New therapeutic options are being discovered and introduced in the market through increased research and development funding from pharmaceutical companies and healthcare providers. Improved knowledge of the pathophysiology of CSU is leading to more effective tailored medicines that provide better symptom alleviation than conventional approaches. The global chronic spontaneous urticaria market is affected by the ability to administer medications subcutaneously. The method is highly effective as it allows complete absorption of the drug without affecting patient's peripheral system and no chances of injury to the vessels and nerves.
Novartis reported positive top-line data in August 2023 from the Phase III REMIX-1 and REMIX-2 studies assessing the BTK inhibitor remibrutinib 25 mg b.i.d. in patients with chronic spontaneous urticaria (CSU). Remibrutinib, if authorized, could be the first medication in a decade to treat chronic spontaneous urticaria (CSU), providing a straightforward and efficient alternative for 60% of patients for whom H1-antihistamines are ineffective.
Significant Investments for Expediting Research and Development
The growth of global chronic spontaneous urticaria market is being driven by a constant focus on research and development activities by pharmaceutical companies. Major companies in the market are spending huge amounts in conducting research activities to find innovative solutions for treating patients with CSU. Through research, companies can discover various insights into the factors revolving around the treatment of the disease. All these factors indicate that there is a strong association between the research efforts and the increasing growth trajectory of the global chronic spontaneous urticaria market. In January 2024, Enanta Pharmaceuticals, a clinical-stage biotechnology company, provided updates on its research and development programs and the outlook for the year 2024, at the 42nd Annual J.P. Morgan healthcare conference. The company announced its expansion into immunology and discovery programs to treat CSU.
Significant Investments for Improving Healthcare Infrastructure
Noticing the increasing need for efficient CSU therapies, major players in the global chronic spontaneous urticaria market are stepping up their efforts to improve healthcare infrastructure through investments. The calculated action is motivated by the rising incidence of CSU, a disorder marked by swelling and hives that develop suddenly and have no apparent reason. These businesses hope to create and offer novel, more potent treatment alternatives by investing more money in the healthcare infrastructure. In addition to demonstrating their dedication to meet the unmet needs of CSU patients, the investment shows the market has the potential to develop significantly due to better treatments resulting in favorable patient outcomes and a rise in demand for cutting-edge therapies.
Many companies in the global chronic spontaneous urticaria market are increasing their investments in the market. For instance, in April 2023, Evommune, Inc. announced the completion of USD 50 million Series B financing to develop new innovative technologies to treat inflammatory diseases such as CSU. Along with current investors EQT Life Sciences and SymBiosis, new investor Arix Bioscience led the funding.
Availability of Novel Medications for Treatment
The development and accessibility of therapeutic alternatives, such as immunosuppressants, biologic therapies, and antihistamines, are the main factors driving the global chronic spontaneous urticaria market. These medications are highly effective due to which their demand in the market is increasing drastically. Medical research advancements have led to the development of many such medications, with more under clinical trials. Second-line drugs like leukotriene receptor antagonists (like montelukast), oral corticosteroids (like prednisone), H2 blockers (like cimetidine), and biologics (like omalizumab; Xolair) may be prescribed to treat patients with refractory symptoms. In January 2024, Evommune, Inc., a clinical-stage biotechnology company, announced the beginning of its human study for Phase 1, to find out EVO756 in adults with CSU. If the trial turns out to be successful, then EVO756 can be the first oral treatment for several diseases such as CSU and inflammatory itch.
Clinical Advantages of Subcutaneous Drugs
Subcutaneous drugs absorb easily without any side effects. Subcutaneous drugs offer numerous clinical benefits such as patient convenience, reduced cost, fewer side effects, enhanced patient satisfaction, and improved drug absorption. With less frequent doses and consistent medication absorption, it can potentially minimize the need for hospital visits and increase patient compliance by enabling self-administration at home. Subcutaneous drugs are highly effective offering a reliable treatment for CSU. Home administration eliminates the need for expensive hospital visits and decreases the demand for medical personnel, resulting in lower healthcare expenses. Compared to intravenous administration, subcutaneous administration often leads to fewer adverse events, particularly those related to infusions, such as infections and hypersensitivity reactions.
On February 16, 2024, Genentech, a member of Roche Group, announced Xolair for the treatment of anaphylaxis and allergic reactions caused due to food allergies in children and adults. It received approval from the U.S. Food and Drug Administration (FDA) and has been cleared for use of treating CSU.
Asia-Pacific to Grow at the Fastest Rate During the Forecast Period
Several countries in Asia-Pacific are going to observe rapid growth in the global chronic spontaneous urticaria market. Economic growth in countries like China and India is going to play a major role in market expansion along with the countries such as China, Japan, India, Australia, and South Korea. The trend can be attributed to the region's increasing population growth, government initiatives, and improving healthcare infrastructure. People are becoming more aware of the illness and its implications, which increases the demand for effective therapies. Additionally, by giving patients more treatment options, the emergence of new pharmaceutical businesses in the market with a focus on cutting-edge CSU therapy promotes market expansion.
On 16 February 2024, Dupixent, a drug used for the treatment of CSU, jointly developed by Sanofi and Regeneron, was granted permission for manufacturing and marketing by the Ministry of Health, Labour and Welfare (MHLW) in Japan.
Future Market Scenario (2024 - 2031F)
To handle the complexity of CSU, businesses are actively seeking novel solutions. For example, Amalizumab, a monoclonal antibody that targets immunoglobulin E (IgE), was developed and is now authorized for use in CSU.
It is anticipated that the creation of novel diagnostic instruments and methodologies will enhance the precision and promptness of CSU diagnosis, resulting in improved patient outcomes. For instance, blood and skin prick tests can be used to determine the underlying cause of CSU, which enables doctors to adjust treatment regimens accordingly.
Advancement in treatment options like targeted therapies and biologics will lead to the expansion of the global spontaneous urticaria market.
Patients are more likely to receive access to cutting-edge CSU medicines and treatments as global healthcare spending rises.
Key Players Landscape and Outlook
The chronic spontaneous urticaria market is expected to experience significant growth in the coming years, driven by factors such as increasing prevalence of urticaria, rising healthcare spending, and technological advancements in medicine and digital health. The market is highly competitive, with key players including Roche, Novartis, Sanofi, AstraZeneca, and GlaxoSmithKline, and others. The global chronic spontaneous urticaria market is witnessing a significant shift towards strategic partnerships among leading companies in the industry. By working together, these organizations can overcome technical and clinical barriers that would otherwise prevent them from moving forward independently.
A Complete Response Letter (CRL) for the supplementary Biologics Licence Application for Dupixent was made available by the U.S. FDA in October 2023. A medication called Dupixent used to treat CSU, is being developed in collaboration with the American biotechnology company Regeneron and Sanofi.
All segments will be provided for all regions and countries covered
Companies mentioned above DO NOT hold any order as per market share and can be changed as per information available during research work.