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市场调查报告书
商品编码
1380413
全球胜肽药物偶联物市场2023-2030Global Peptide Drug Conjugates Market 2023-2030 |
预计全球胜肽药物缀合物市场在预测期(2023-2030年)将以9.4%的CAGR成长。此市场归因于癌症和代谢紊乱盛行率上升、新药研发投资增加以及药物开发技术进步等因素。根据 Globocan 2020,癌症病例数为 50,550,287 例。其中,全球新增病例总数19,292,789例。
全球胜肽药物偶联物市场按类型和产品细分。根据类型,市场分为诊断和治疗。根据产品,市场细分为 Melflufen、Lutetium、ANG1005、BT1718 和 CBX-12。在这一类型中,由于新兴的标靶治疗药物具有增强的肿瘤渗透性和选择性,因此预计治疗细分市场将占据相当大的市场份额。
其中,melflufen细分市场预计将在全球胜肽药物偶联物市场中占据相当大的份额。此细分市场的成长归因于人们对当前治疗选择的认识不断提高、有利的报销政策、Melflufen 的推出以及PDC 药物在癌症治疗中的快速应用。2021 年2 月,FDA 批准了第一个抗癌胜肽药物结合物,美法崙氟芬酰胺或美氟芬,与地塞米松合併使用。基于2期HORIZON研究,该产品由瑞典生物技术公司Oncopeptides AB开发,获得加速批准。患有难治性多发性骨髓瘤的成年患者,曾经接受过至少 4 种治疗,且其疾病对至少 1 种蛋白酶体抑制剂、1 种免疫调节剂和 1 种 CD38 定向单株抗体难以治疗。
全球胜肽药物偶联物市场根据地理位置进一步细分,包括北美(美国和加拿大)、欧洲(英国、义大利、西班牙、德国、法国和欧洲其他地区)、亚太地区(印度、中国、日本、韩国和亚洲其他地区)以及世界其他地区(中东和非洲以及拉丁美洲)。其中,由于开发和商业化新输送系统的投资不断增加,预计亚太地区将在全球市场中占据显着份额。
在所有地区中,北美地区预计在预测期内将以相当大的CAGR成长。推动北美市场的主要因素是该地区癌症病例数量的增加,预计这肯定会影响未来几年胜肽药物缀合物市场的成长。根据美国癌症协会 (ACS) 的数据,2022 年,美国报告了约 1,918,030 例新癌症病例和 609,360 例癌症死亡病例。根据英国皇家学会出版组织报道,HPRP-A1-TAT是一种杂合胜肽,能破坏细胞膜,导致细胞质内容物快速渗漏,具有很强的抗癌活性。
服务全球胜肽药物缀合物市场的主要公司包括: Angiochem Inc.、Bicycle Therapeutics, Inc.、Cybrexa Therapeutics Inc.、Novartis AG、Oncopeptides AB 等。市场参与者透过各种策略(包括併购、合作、合作、融资和新产品发布),为市场成长做出了巨大贡献,以保持市场竞争力。例如,2023 年 9 月,总部位于日本神奈川的生物製药上市公司 PeptiDream Inc. 与罗氏集团旗下美国基因泰克公司签订了一项新的多目标合作和许可协议,旨在发现和开发新型大环肽-放射性同位素药物缀合物。
Title: Global Peptide Drug Conjugates Market Size, Share & Trends Analysis Report by Type (Diagnostic and Therapeutic), and by Product (Melflufen, Lutetium, ANG1005, BT1718 and CBX-12),Forecast Period (2023-2030).
The global peptide drug conjugates market is anticipated to grow at a CAGR of 9.4% during the Forecast Period (2023-2030). The market is attributed to factors including the increasing prevalence of cancer and metabolic disorders, rising investments in the R&D of novel drugs, and technological advancements in drug development. According to the Globocan 2020, number of cancer cases were 50,550,287. Of which, the total number of new cases 19,292,789 around the globe.
The global peptide drug conjugates market is segmented on the type, and product. Based on the type, the market is sub-segmented into diagnostic and therapeutic. Based on the product, the market is sub-segmented into melflufen, lutetium, ANG1005, BT1718 and CBX-12. Among the type, the therapeutic sub-segment is anticipated to hold a considerable share of the market, owing to the emerging targeted therapeutic that present increased tumor penetration and selectivity.
Among the product, the melflufen sub-segment is expected to hold a considerable share of the global Peptide Drug Conjugates market. The segmental growth is attributed to the owing to increasing awareness about current treatment options, favorable reimbursement policies, the launch of Melflufen and rapid uptake of PDC drugs in cancer therapy., In February 2021, the FDA approved the first anticancer peptide-drug conjugate, melphalan flufenamide, or melflufen, for use in combination with dexamethasone. Based on the phase 2 HORIZON research, the product, developed by the Swedish biotech company Oncopeptides AB, received accelerated approval. In adult patients with refractory multiple myeloma, who have received at least 4 prior lines of therapy and whose disease is refractory to at least 1 proteasome inhibitor, 1 immunomodulatory agent, and 1 CD38-directed monoclonal antibody.
The global peptide drug conjugates market is further segmented based on geography including North America (the US, and Canada), Europe (UK, Italy, Spain, Germany, France, and the Rest of Europe), Asia-Pacific (India, China, Japan, South Korea, and Rest of Asia), and the Rest of the World (the Middle East & Africa, and Latin America). Among these, Asia-Pacific is anticipated to hold a prominent share of the market across the globe, owing to the rising investments to develop and commercialize new delivery systems.
Among all regions, the North America regions is anticipated to grow at a considerable CAGR over the forecast period. The major factors driving the North America market is the increasing number of cancer cases across the region is estimated to certainly impact the peptide drug conjugates market growth in upcoming years. According to the American Cancer Society (ACS), in 2022, around 1,918,030 new cancer cases and 609,360 cancer mortalities were reported in the US. As per the reports of Royal Society Publishing Organization, HPRP-A1-TAT, a hybrid peptide, can destroy the cell membrane to cause rapid leakage of cytoplasmic contents, and has a strong anti-cancer activity.
The major companies serving the global peptide drug conjugates market include: Angiochem Inc., Bicycle Therapeutics, Inc., Cybrexa Therapeutics Inc., Novartis AG, Oncopeptides AB, and others. The market players are considerably contributing to the market growth by the adoption of various strategies including mergers and acquisitions, partnerships, collaborations, funding, and new product launches, to stay competitive in the market. For instance, in September 2023, PeptiDream Inc., a public Kanagawa, Japan-based biopharmaceutical company entered into a new multi-target collaboration and license agreement with US based Genentech, a member of the Roche Group, targeted on the discovery and development of novel macrocyclic peptide-radioisotope drug conjugates.