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全球支架技术市场 2023-2030Global Scaffold Technology Market 2023-2030 |
预计在预测期(2023-2030年),全球支架技术市场将以10.2%的复合CAGR成长。全球对器官移植、重建手术的需求不断增长,以及基于 3D 基底的 3D 矩阵设计的研发活动的增加,正在促进市场成长。细胞间交互作用、高通量扫描、转染和细胞迁移测定等 3D 培养测定均使用支架技术。此外,血管化和器官植入再生等组织培养应用于损伤和患病器官或组织的治疗,也将进一步为支架技术的发展提供潜在机会。
全球支架技术市场按类型、疾病类型、应用和最终用户细分。根据类型,市场细分为水凝胶、聚合物支架、微图案表面微孔板和奈米纤维支架。根据疾病类型,市场细分为骨科、肌肉骨骼和脊椎、癌症、皮肤和外皮、牙科等。根据应用,市场细分为干细胞治疗、再生医学和组织工程以及药物开发。此外,根据最终用户,市场细分为生物技术和製药组织、研究实验室和研究所以及医院和诊断中心。在该类型中,由于水凝胶微加工製程的技术进步预计将在预测期内加速该细分市场的成长,因此预计水凝胶细分市场将占据相当大的市场份额。该公司正在推出用于细胞移植、药物储存和再狭窄屏障的新型水凝胶。例如,2021 年3 月,Bio-Techne Corporation 宣布推出Cultrex UltiMatrix 减少生长因子基底膜萃取物(RGF BME),这是一种细胞外基质水凝胶,可为培养类器官和多能干细胞提供显着的性能和一致性优势。
其中,干细胞治疗、再生医学和组织工程以及药物开发细分领域预计将在全球支架技术市场中占据相当大的份额。支架技术在重建手术、美容手术、腹壁修復、牙周病学、软组织肿瘤修復和大肠直肠治疗的应用越来越频繁。根据国际美容整形外科协会 (ISAPS) 的数据,2021 年整形外科医生实施的手术总体增长了 19.3%,全球范围内实施的手术数量超过 1,280 万例,非手术手术数量超过 1,750 万例。移植血液干细胞是最知名且最常使用的干细胞治疗方法。它可用于治疗免疫系统和血液系统疾病,以及在某些癌症治疗后修復血液系统。在欧洲,每年约有 26,000 名患者使用血液干细胞进行治疗。
此外,研究人员对支架技术在再生医学领域的广泛使用越来越感兴趣。例如,2020 年 11 月,维克森林再生医学研究所 (WFIRM) 的科学家推出了一种可用于软骨再生的混合组织结构。它是利用 3D 生物列印技术创建的。因此,组织发育研究的不断扩展可归因于节段扩展。
Global Scaffold technology Market Size, Share & Trends Analysis Report by Type (Hydrogels, Polymeric Scaffolds, Micropatterned Surface Microplates and Nanofiber Based Scaffolds),by Disease Type (Orthopedics, Musculoskeletal, & Spine, Cancer, Skin & Integumentary, Dental and Others),by Application (Stem Cell Therapy, Regenerative Medicine,& Tissue Engineering, and Drug Development) and by End-User (Biotechnology & Pharmaceutical Organizations, Research Laboratories & Institutes, Hospitals & Diagnostic Centers)Forecast Period (2023-2030)
The global scaffold technology market is anticipated to grow at a considerable CAGR of 10.2% during the forecast period (2023-2030). The rising demand for organ transplant, reconstruction procedures globally and increase in R&D initiatives on the design of a 3D matrix that is based on 3D substrates is enabling the market growth. 3D culture assays such as cell to cell interactions, high throughput scanning, transfections, and cell migration assays all use scaffold technology. In addition, the tissue culture such as vascularization and organ implant regeneration applied in the treatment of damaged and diseased organs or tissues will further provide potential opportunities for the growth of the scaffold technology
The global scaffold technology market is segmented by the type, disease type, application, and end-user. Based on the type, the market is sub-segmented into hydrogels, polymeric scaffolds, micropatterned surface microplates and nanofiber-based scaffolds. Based on disease type the market is sub-segmented into orthopedics, musculoskeletal, & spine, cancer, skin & integumentary, dental and others. Based on the application, the market is sub-segmented into stem cell therapy, regenerative medicine& tissue engineering, and drug development. Further, based on the end-user, the market is sub-segmented into biotechnology & pharmaceutical organizations, research laboratories & institutes, and hospitals & diagnostic centers. Among the type, the hydrogels sub-segment is anticipated to hold a considerable share of the market owing to technological advancements in microfabrication procedures for hydrogels are anticipated to accelerate the segment growth during the forecast period. Companies are launching new hydrogels for cell transplantation, drug depots, and a barrier against restenosis. For instance, in March, 2021 Bio-Techne Corporation announced the release of Cultrex UltiMatrix Reduced Growth Factor Basement Membrane Extract (RGF BME), an extracellular matrix hydrogel that provides significant performance and consistency benefits for culturing organoids and pluripotent stem cells.
Among the application, the stem cell therapy, regenerative medicine & tissue engineering, and drug development sub-segment is expected to hold a considerable share of the global scaffold technology market. Scaffold technology is being utilized increasingly frequently in reconstructive surgeries, aesthetic surgeries, abdominal wall repair, periodontology, soft tissue tumor repair and colorectal treatments. According to the International Society of Aesthetic Plastic Surgery (ISAPS), a 19.3% overall increase in procedures performed by plastic surgeons in 2021 with more than 12.8 million surgical, and 17.5 million non-surgical, procedures performed globally. Transplanting blood stem cells is the most well-known and often used stem cell treatment. It may be used to treat immune system and blood system disorders, as well as to repair the blood system following treatment for certain cancers. Blood stem cells are used to treat around 26,000 patients annually in Europe.
Furthermore, researchers have become increasingly interested in the widespread use of scaffold technologies in the field of regenerative medicine. For instance, in November 2020, Wake Forest Institute for Regenerative Medicine (WFIRM) scientists, introduced a hybrid tissue structure that can be used for cartilage regeneration. It was created with the use of 3D bioprinting technology. As a result, the expanding research into tissue development can be ascribed to segment expansion.
The global scaffold technology market is further segmented based on geography including North America (the US, and Canada), Europe (UK, Italy, Spain, Germany, France, and the Rest of Europe), Asia-Pacific (India, China, Japan, South Korea, and Rest of Asia), and the Rest of the World (the Middle East & Africa, and Latin America. Among these, Asia-Pacific is anticipated to exhibit fastest CAGR during the forecast period. The growing presence of government organizations that conduct regenerative medicine and stem cell research is a key factor driving the regional market growth. India has a vibrant stem cell research ecosystem, with both private and government institutions contributing to the field. For instance, in 2021 financial assistance for stem cell research activities is being provided by the Indian Government. The Government of India has undertaken stem cell research through various Departments/ Institutions, including the Indian Council of Medical Research (ICMR), Department of Biotechnology (DBT), and Department of Science and Technology (DST). Additionally, increasing public consciousness about the use of organ transplants and increased expenditures in healthcare infrastructure in countries such as India and China also contribute to the regional market's expansion.
in the high incidences of cancer, increase in number of organ transplantation, and expansion of biotechnology & pharmaceutical companies is a key factor driving demand for scaffold technology. Growing R&D across the region is further contributing regional market share. For instance, in April 2023, Systemic Bio opened its new lab in Texas, US for hydrogel scaffold manufacturing and research and development activities for organ-on-a-chip technology to enhance drug discovery and development. Disease such as cancer has a major impact in the US. Cancer surgery is a common part of diagnosing and treating cancer. Surgery can show the size of the cancer and whether it has spread, which helps to figure out the cancer's stage. In 2020, an estimated 1,806,590 new cases of cancer were diagnosed in the US. The most common cancers were breast cancer, lung and bronchus cancer, prostate cancer, colon and rectum cancer, melanoma of the skin, bladder cancer, and non-Hodgkin lymphoma. Additionally due to presence of major companies including Akron Biotech, 3D Biotek LLC, Thermo Fisher Scientific Inc., Molecular Matrix Inc., Xanofi, and Corning Incorporated is propelling the region's growth.
The major companies serving the scaffold technology market include Becton, Dickinson and Company, Thermo Fisher Scientific Inc., Lonza Group Ltd., 3D Biotek, LLC, Molecular Matrix, Inc., PELOBIOTECH GmbH, India Medtronic Pvt Ltd., Avacta Life Sciences Ltd., AbbVie, and others. The market players are considerably contributing to the market growth by the adoption of various strategies including mergers and acquisitions, partnerships, collaborations, funding, and new product launches, to stay competitive in the market. For instance, in March 2022, Evonik and BellaSeno, a developer of 3D-printed absorbable scaffolds, were working together to commercialize innovative 3D-printed scaffolds for bone regeneration. The bone scaffolds are made with Evonik's Resomer polymers and are used for large and complex bone defects. Both companies initially began collaborating in 2019 on scaffolds for chest wall and breast reconstruction.