The global market for Perfusion Bioreactors was estimated to be worth US$ 703 million in 2024 and is forecast to a readjusted size of US$ 1153 million by 2031 with a CAGR of 7.2% during the forecast period 2025-2031.
This report provides a comprehensive assessment of recent tariff adjustments and international strategic countermeasures on Perfusion Bioreactors cross-border industrial footprints, capital allocation patterns, regional economic interdependencies, and supply chain reconfigurations.
Perfusion is a means to maintain a cell culture bioreactor in which equivalent volumes of media are simultaneously added and removed from the reactor while the cells are retained in the reactor. Perfusion bioreactors offer several advantages over traditional fed-batch bioreactors when addressing problems of scalability and increasing demand. Perfusion bioreactors culture cells over much longer periods, even months, by continuously feeding the cells with fresh media and removing spent media while keeping cells in culture. In perfusion there are different ways to keep the cells in culture while removing spent media.
The main global perfusion bioreactor manufacturers include Sartorius AG,Cytiva,Thermo Fisher,Eppendorf AG and ZETA, etc. The top five global manufacturers account for more than 79% of the market share. Currently, North America is the world's largest perfusion bioreactor market, accounting for more than 40% of the market share, followed by the Asia-Pacific and European markets, which together account for more than 40% of the market share.
The driving factors of the perfusion bioreactor market mainly include the following:
The rapid development of the biopharmaceutical industry
As people pay more attention to health, the demand for biopharmaceutical products continues to grow. As one of the main application areas of perfusion bioreactors, the rapid development of the biopharmaceutical industry has directly promoted the market demand for perfusion bioreactors. In the process of research and development and production, biopharmaceutical companies need efficient and stable bioreactors to support key steps such as cell culture and virus amplification, and perfusion bioreactors are important tools to meet these needs.
Continuous progress in biotechnology
The rapid development of biotechnology has provided more application areas and possibilities for perfusion bioreactors. New cell culture technology, biosynthesis technology, and gene editing technology continue to emerge, making the functions of perfusion bioreactors more diversified and able to meet the production needs of more types of biopharmaceuticals and biotechnology products. In addition, the advancement of biotechnology has also promoted the continuous innovation and upgrading of perfusion bioreactor technology, improving its production efficiency and performance.
Support from government policies
Governments of various countries have introduced policies to encourage the development of biopharmaceutical and biotechnology industries. These policies not only provide biopharmaceutical companies with preferential measures such as financial support and tax incentives, but also promote the construction and improvement of related industrial chains. Driven by these policies, the biopharmaceutical and biotechnology industries have developed rapidly, which in turn has driven the growth of the perfusion bioreactor market.
Market competition and technological innovation
The global perfusion bioreactor market is highly competitive, and major companies are actively developing new products and expanding new markets. This market competition has promoted the continuous innovation and upgrading of perfusion bioreactor technology, improving the performance and quality of products. At the same time, cooperation and mergers and acquisitions between companies have also accelerated the dissemination and application of technology, further promoting market growth.
Emerging market opportunities
With the rapid development of emerging fields such as biosimilars and gene editing, perfusion bioreactors have broad application prospects in these fields. These emerging markets provide new development opportunities and growth space for perfusion bioreactors. For example, in the field of biosimilars, perfusion bioreactors can be used to produce high-quality biosimilars; in the field of gene editing, perfusion bioreactors can be used to support processes such as the expansion and differentiation of gene-edited cells.
In summary, the driving factors of the perfusion bioreactor market mainly include the rapid development of the biopharmaceutical industry, the continuous advancement of biotechnology, the support of government policies, market competition and technological innovation, and emerging market opportunities. These factors have jointly promoted the rapid growth and development of the perfusion bioreactor market.
This report aims to provide a comprehensive presentation of the global market for Perfusion Bioreactors, focusing on the total sales volume, sales revenue, price, key companies market share and ranking, together with an analysis of Perfusion Bioreactors by region & country, by Type, and by Application.
The Perfusion Bioreactors market size, estimations, and forecasts are provided in terms of sales volume (K Units) and sales revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. With both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Perfusion Bioreactors.
Market Segmentation
By Company
- Sartorius AG
- Cytiva
- Thermo Fisher
- Eppendorf AG
- ZETA
- Infors HT
- Applikon Biotechnology (Getinge)
- Bioengineering AG
- 3D Biotek
- PBS Biotech, Inc.
- Cell Culture Company
- Zellwerk GmbH
Segment by Type
- Small Scale (≤100 Liters)
- Mid-Scale (100 to 1,000 Liters)
- Large Scale (>1,000 Liters)
Segment by Application
- Biopharmaceutical
- Biotechnology
- Others
By Region
- North America
- Asia-Pacific
- China
- Japan
- South Korea
- Southeast Asia
- India
- Australia
- Rest of Asia-Pacific
- Europe
- Germany
- France
- U.K.
- Italy
- Netherlands
- Nordic Countries
- Rest of Europe
- Latin America
- Mexico
- Brazil
- Rest of Latin America
- Middle East & Africa
- Turkey
- Saudi Arabia
- UAE
- Rest of MEA
Chapter Outline
Chapter 1: Introduces the report scope of the report, global total market size (value, volume and price). This chapter also provides the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.
Chapter 2: Detailed analysis of Perfusion Bioreactors manufacturers competitive landscape, price, sales and revenue market share, latest development plan, merger, and acquisition information, etc.
Chapter 3: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.
Chapter 4: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.
Chapter 5: Sales, revenue of Perfusion Bioreactors in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the market development, future development prospects, market space, and market size of each country in the world.
Chapter 6: Sales, revenue of Perfusion Bioreactors in country level. It provides sigmate data by Type, and by Application for each country/region.
Chapter 7: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product sales, revenue, price, gross margin, product introduction, recent development, etc.
Chapter 8: Analysis of industrial chain, including the upstream and downstream of the industry.
Chapter 9: Conclusion.
Table of Contents
1 Market Overview
- 1.1 Perfusion Bioreactors Product Introduction
- 1.2 Global Perfusion Bioreactors Market Size Forecast
- 1.2.1 Global Perfusion Bioreactors Sales Value (2020-2031)
- 1.2.2 Global Perfusion Bioreactors Sales Volume (2020-2031)
- 1.2.3 Global Perfusion Bioreactors Sales Price (2020-2031)
- 1.3 Perfusion Bioreactors Market Trends & Drivers
- 1.3.1 Perfusion Bioreactors Industry Trends
- 1.3.2 Perfusion Bioreactors Market Drivers & Opportunity
- 1.3.3 Perfusion Bioreactors Market Challenges
- 1.3.4 Perfusion Bioreactors Market Restraints
- 1.4 Assumptions and Limitations
- 1.5 Study Objectives
- 1.6 Years Considered
2 Competitive Analysis by Company
- 2.1 Global Perfusion Bioreactors Players Revenue Ranking (2024)
- 2.2 Global Perfusion Bioreactors Revenue by Company (2020-2025)
- 2.3 Global Perfusion Bioreactors Players Sales Volume Ranking (2024)
- 2.4 Global Perfusion Bioreactors Sales Volume by Company Players (2020-2025)
- 2.5 Global Perfusion Bioreactors Average Price by Company (2020-2025)
- 2.6 Key Manufacturers Perfusion Bioreactors Manufacturing Base and Headquarters
- 2.7 Key Manufacturers Perfusion Bioreactors Product Offered
- 2.8 Key Manufacturers Time to Begin Mass Production of Perfusion Bioreactors
- 2.9 Perfusion Bioreactors Market Competitive Analysis
- 2.9.1 Perfusion Bioreactors Market Concentration Rate (2020-2025)
- 2.9.2 Global 5 and 10 Largest Manufacturers by Perfusion Bioreactors Revenue in 2024
- 2.9.3 Global Top Manufacturers by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Perfusion Bioreactors as of 2024)
- 2.10 Mergers & Acquisitions, Expansion
3 Segmentation by Type
- 3.1 Introduction by Type
- 3.1.1 Small Scale (<=100 Liters)
- 3.1.2 Mid-Scale (100 to 1,000 Liters)
- 3.1.3 Large Scale (>1,000 Liters)
- 3.2 Global Perfusion Bioreactors Sales Value by Type
- 3.2.1 Global Perfusion Bioreactors Sales Value by Type (2020 VS 2024 VS 2031)
- 3.2.2 Global Perfusion Bioreactors Sales Value, by Type (2020-2031)
- 3.2.3 Global Perfusion Bioreactors Sales Value, by Type (%) (2020-2031)
- 3.3 Global Perfusion Bioreactors Sales Volume by Type
- 3.3.1 Global Perfusion Bioreactors Sales Volume by Type (2020 VS 2024 VS 2031)
- 3.3.2 Global Perfusion Bioreactors Sales Volume, by Type (2020-2031)
- 3.3.3 Global Perfusion Bioreactors Sales Volume, by Type (%) (2020-2031)
- 3.4 Global Perfusion Bioreactors Average Price by Type (2020-2031)
4 Segmentation by Application
- 4.1 Introduction by Application
- 4.1.1 Biopharmaceutical
- 4.1.2 Biotechnology
- 4.1.3 Others
- 4.2 Global Perfusion Bioreactors Sales Value by Application
- 4.2.1 Global Perfusion Bioreactors Sales Value by Application (2020 VS 2024 VS 2031)
- 4.2.2 Global Perfusion Bioreactors Sales Value, by Application (2020-2031)
- 4.2.3 Global Perfusion Bioreactors Sales Value, by Application (%) (2020-2031)
- 4.3 Global Perfusion Bioreactors Sales Volume by Application
- 4.3.1 Global Perfusion Bioreactors Sales Volume by Application (2020 VS 2024 VS 2031)
- 4.3.2 Global Perfusion Bioreactors Sales Volume, by Application (2020-2031)
- 4.3.3 Global Perfusion Bioreactors Sales Volume, by Application (%) (2020-2031)
- 4.4 Global Perfusion Bioreactors Average Price by Application (2020-2031)
5 Segmentation by Region
- 5.1 Global Perfusion Bioreactors Sales Value by Region
- 5.1.1 Global Perfusion Bioreactors Sales Value by Region: 2020 VS 2024 VS 2031
- 5.1.2 Global Perfusion Bioreactors Sales Value by Region (2020-2025)
- 5.1.3 Global Perfusion Bioreactors Sales Value by Region (2026-2031)
- 5.1.4 Global Perfusion Bioreactors Sales Value by Region (%), (2020-2031)
- 5.2 Global Perfusion Bioreactors Sales Volume by Region
- 5.2.1 Global Perfusion Bioreactors Sales Volume by Region: 2020 VS 2024 VS 2031
- 5.2.2 Global Perfusion Bioreactors Sales Volume by Region (2020-2025)
- 5.2.3 Global Perfusion Bioreactors Sales Volume by Region (2026-2031)
- 5.2.4 Global Perfusion Bioreactors Sales Volume by Region (%), (2020-2031)
- 5.3 Global Perfusion Bioreactors Average Price by Region (2020-2031)
- 5.4 North America
- 5.4.1 North America Perfusion Bioreactors Sales Value, 2020-2031
- 5.4.2 North America Perfusion Bioreactors Sales Value by Country (%), 2024 VS 2031
- 5.5 Europe
- 5.5.1 Europe Perfusion Bioreactors Sales Value, 2020-2031
- 5.5.2 Europe Perfusion Bioreactors Sales Value by Country (%), 2024 VS 2031
- 5.6 Asia Pacific
- 5.6.1 Asia Pacific Perfusion Bioreactors Sales Value, 2020-2031
- 5.6.2 Asia Pacific Perfusion Bioreactors Sales Value by Region (%), 2024 VS 2031
- 5.7 South America
- 5.7.1 South America Perfusion Bioreactors Sales Value, 2020-2031
- 5.7.2 South America Perfusion Bioreactors Sales Value by Country (%), 2024 VS 2031
- 5.8 Middle East & Africa
- 5.8.1 Middle East & Africa Perfusion Bioreactors Sales Value, 2020-2031
- 5.8.2 Middle East & Africa Perfusion Bioreactors Sales Value by Country (%), 2024 VS 2031
6 Segmentation by Key Countries/Regions
- 6.1 Key Countries/Regions Perfusion Bioreactors Sales Value Growth Trends, 2020 VS 2024 VS 2031
- 6.2 Key Countries/Regions Perfusion Bioreactors Sales Value and Sales Volume
- 6.2.1 Key Countries/Regions Perfusion Bioreactors Sales Value, 2020-2031
- 6.2.2 Key Countries/Regions Perfusion Bioreactors Sales Volume, 2020-2031
- 6.3 United States
- 6.3.1 United States Perfusion Bioreactors Sales Value, 2020-2031
- 6.3.2 United States Perfusion Bioreactors Sales Value by Type (%), 2024 VS 2031
- 6.3.3 United States Perfusion Bioreactors Sales Value by Application, 2024 VS 2031
- 6.4 Europe
- 6.4.1 Europe Perfusion Bioreactors Sales Value, 2020-2031
- 6.4.2 Europe Perfusion Bioreactors Sales Value by Type (%), 2024 VS 2031
- 6.4.3 Europe Perfusion Bioreactors Sales Value by Application, 2024 VS 2031
- 6.5 China
- 6.5.1 China Perfusion Bioreactors Sales Value, 2020-2031
- 6.5.2 China Perfusion Bioreactors Sales Value by Type (%), 2024 VS 2031
- 6.5.3 China Perfusion Bioreactors Sales Value by Application, 2024 VS 2031
- 6.6 Japan
- 6.6.1 Japan Perfusion Bioreactors Sales Value, 2020-2031
- 6.6.2 Japan Perfusion Bioreactors Sales Value by Type (%), 2024 VS 2031
- 6.6.3 Japan Perfusion Bioreactors Sales Value by Application, 2024 VS 2031
- 6.7 South Korea
- 6.7.1 South Korea Perfusion Bioreactors Sales Value, 2020-2031
- 6.7.2 South Korea Perfusion Bioreactors Sales Value by Type (%), 2024 VS 2031
- 6.7.3 South Korea Perfusion Bioreactors Sales Value by Application, 2024 VS 2031
- 6.8 Southeast Asia
- 6.8.1 Southeast Asia Perfusion Bioreactors Sales Value, 2020-2031
- 6.8.2 Southeast Asia Perfusion Bioreactors Sales Value by Type (%), 2024 VS 2031
- 6.8.3 Southeast Asia Perfusion Bioreactors Sales Value by Application, 2024 VS 2031
- 6.9 India
- 6.9.1 India Perfusion Bioreactors Sales Value, 2020-2031
- 6.9.2 India Perfusion Bioreactors Sales Value by Type (%), 2024 VS 2031
- 6.9.3 India Perfusion Bioreactors Sales Value by Application, 2024 VS 2031
7 Company Profiles
- 7.1 Sartorius AG
- 7.1.1 Sartorius AG Company Information
- 7.1.2 Sartorius AG Introduction and Business Overview
- 7.1.3 Sartorius AG Perfusion Bioreactors Sales, Revenue, Price and Gross Margin (2020-2025)
- 7.1.4 Sartorius AG Perfusion Bioreactors Product Offerings
- 7.1.5 Sartorius AG Recent Development
- 7.2 Cytiva
- 7.2.1 Cytiva Company Information
- 7.2.2 Cytiva Introduction and Business Overview
- 7.2.3 Cytiva Perfusion Bioreactors Sales, Revenue, Price and Gross Margin (2020-2025)
- 7.2.4 Cytiva Perfusion Bioreactors Product Offerings
- 7.2.5 Cytiva Recent Development
- 7.3 Thermo Fisher
- 7.3.1 Thermo Fisher Company Information
- 7.3.2 Thermo Fisher Introduction and Business Overview
- 7.3.3 Thermo Fisher Perfusion Bioreactors Sales, Revenue, Price and Gross Margin (2020-2025)
- 7.3.4 Thermo Fisher Perfusion Bioreactors Product Offerings
- 7.3.5 Thermo Fisher Recent Development
- 7.4 Eppendorf AG
- 7.4.1 Eppendorf AG Company Information
- 7.4.2 Eppendorf AG Introduction and Business Overview
- 7.4.3 Eppendorf AG Perfusion Bioreactors Sales, Revenue, Price and Gross Margin (2020-2025)
- 7.4.4 Eppendorf AG Perfusion Bioreactors Product Offerings
- 7.4.5 Eppendorf AG Recent Development
- 7.5 ZETA
- 7.5.1 ZETA Company Information
- 7.5.2 ZETA Introduction and Business Overview
- 7.5.3 ZETA Perfusion Bioreactors Sales, Revenue, Price and Gross Margin (2020-2025)
- 7.5.4 ZETA Perfusion Bioreactors Product Offerings
- 7.5.5 ZETA Recent Development
- 7.6 Infors HT
- 7.6.1 Infors HT Company Information
- 7.6.2 Infors HT Introduction and Business Overview
- 7.6.3 Infors HT Perfusion Bioreactors Sales, Revenue, Price and Gross Margin (2020-2025)
- 7.6.4 Infors HT Perfusion Bioreactors Product Offerings
- 7.6.5 Infors HT Recent Development
- 7.7 Applikon Biotechnology (Getinge)
- 7.7.1 Applikon Biotechnology (Getinge) Company Information
- 7.7.2 Applikon Biotechnology (Getinge) Introduction and Business Overview
- 7.7.3 Applikon Biotechnology (Getinge) Perfusion Bioreactors Sales, Revenue, Price and Gross Margin (2020-2025)
- 7.7.4 Applikon Biotechnology (Getinge) Perfusion Bioreactors Product Offerings
- 7.7.5 Applikon Biotechnology (Getinge) Recent Development
- 7.8 Bioengineering AG
- 7.8.1 Bioengineering AG Company Information
- 7.8.2 Bioengineering AG Introduction and Business Overview
- 7.8.3 Bioengineering AG Perfusion Bioreactors Sales, Revenue, Price and Gross Margin (2020-2025)
- 7.8.4 Bioengineering AG Perfusion Bioreactors Product Offerings
- 7.8.5 Bioengineering AG Recent Development
- 7.9 3D Biotek
- 7.9.1 3D Biotek Company Information
- 7.9.2 3D Biotek Introduction and Business Overview
- 7.9.3 3D Biotek Perfusion Bioreactors Sales, Revenue, Price and Gross Margin (2020-2025)
- 7.9.4 3D Biotek Perfusion Bioreactors Product Offerings
- 7.9.5 3D Biotek Recent Development
- 7.10 PBS Biotech, Inc.
- 7.10.1 PBS Biotech, Inc. Company Information
- 7.10.2 PBS Biotech, Inc. Introduction and Business Overview
- 7.10.3 PBS Biotech, Inc. Perfusion Bioreactors Sales, Revenue, Price and Gross Margin (2020-2025)
- 7.10.4 PBS Biotech, Inc. Perfusion Bioreactors Product Offerings
- 7.10.5 PBS Biotech, Inc. Recent Development
- 7.11 Cell Culture Company
- 7.11.1 Cell Culture Company Company Information
- 7.11.2 Cell Culture Company Introduction and Business Overview
- 7.11.3 Cell Culture Company Perfusion Bioreactors Sales, Revenue, Price and Gross Margin (2020-2025)
- 7.11.4 Cell Culture Company Perfusion Bioreactors Product Offerings
- 7.11.5 Cell Culture Company Recent Development
- 7.12 Zellwerk GmbH
- 7.12.1 Zellwerk GmbH Company Information
- 7.12.2 Zellwerk GmbH Introduction and Business Overview
- 7.12.3 Zellwerk GmbH Perfusion Bioreactors Sales, Revenue, Price and Gross Margin (2020-2025)
- 7.12.4 Zellwerk GmbH Perfusion Bioreactors Product Offerings
- 7.12.5 Zellwerk GmbH Recent Development
8 Industry Chain Analysis
- 8.1 Perfusion Bioreactors Industrial Chain
- 8.2 Perfusion Bioreactors Upstream Analysis
- 8.2.1 Key Raw Materials
- 8.2.2 Raw Materials Key Suppliers
- 8.2.3 Manufacturing Cost Structure
- 8.3 Midstream Analysis
- 8.4 Downstream Analysis (Customers Analysis)
- 8.5 Sales Model and Sales Channels
- 8.5.1 Perfusion Bioreactors Sales Model
- 8.5.2 Sales Channel
- 8.5.3 Perfusion Bioreactors Distributors
9 Research Findings and Conclusion
10 Appendix
- 10.1 Research Methodology
- 10.1.1 Methodology/Research Approach
- 10.1.1.1 Research Programs/Design
- 10.1.1.2 Market Size Estimation
- 10.1.1.3 Market Breakdown and Data Triangulation
- 10.1.2 Data Source
- 10.1.2.1 Secondary Sources
- 10.1.2.2 Primary Sources
- 10.2 Author Details
- 10.3 Disclaimer