生物医药品受託製造的全球市场:各提供服务类型,各製造的生物製药类型,所使用的表现系统类别,各产业规模,不同企业规模,主要各地区 - 产业趋势与预测(2022年~2035年)
市场调查报告书
商品编码
1130891

生物医药品受託製造的全球市场:各提供服务类型,各製造的生物製药类型,所使用的表现系统类别,各产业规模,不同企业规模,主要各地区 - 产业趋势与预测(2022年~2035年)

Biopharmaceutical Contract Manufacturing Market by Type of Service Offered, Type of Biologic Manufactured, Type of Expression System Used, Scale of Operation, Company Size, and Key Geographical Regions : Industry Trends and Global Forecasts, 2022 - 2035

出版日期: | 出版商: Roots Analysis | 英文 799 Pages | 商品交期: 最快1-2个工作天内

价格

本报告提供生物医药品受託製造市场相关调查分析,提供目前的市场情势与今后十年间的未来可能性,加上主要促进因素和趋势,主要企业等相关之最新资讯。

目录

第1章 序文

第2章 摘要整理

第3章 简介

第4章 市场形势

  • 章概要
  • 生物医药品受託製造商:整体市场形势

第5章 地区的生产能力分析

  • 章概要
  • 主要的前提条件与手法
  • 医药品受託製造设施整体形势
  • 地区的生产能力分析:北美的生物医药品受託製造设施
  • 地区的生产能力分析:欧洲的生物医药品受託製造设施
  • 地区的生产能力分析:亚太地区·其他地区的生物医药品受託製造设施

第6章 北美的生物医药品受託製造

  • 章概要
  • 美国的生物医药品受託製造的法规Scenario
  • 北美的主要的生物医药品CMO

第7章 欧洲的生物医药品受託製造

  • 章概要
  • 欧洲的生物医药品受託製造:法规Scenario
  • 欧洲的主要的生物医药品CMO

第8章 亚太地区·其他地区的生物医药品受託製造

  • 章概要
  • 中国的生物医药品受託製造
  • 中国的主要生物医药品CMO
  • 印度的生物医药品受託製造
  • 印度的主要的生物医药品CMO
  • 日本的生物医药品受託製造
  • 日本的主要的生物医药品CMO
  • 韩国的生物医药品受託製造
  • 韩国的主要的生物医药品CMO
  • 澳洲的生物医药品受託製造
  • 澳洲的主要的生物医药品CMO

第9章 最适合的生物医药品部门

  • 章概要
  • 双特异性抗体
  • 抗体药物复合体(ADC)
  • 细胞治疗
  • 基因治疗
  • 质体DNA

第10章 案例研究:生物相似药的外包

  • 章概要
  • 生物相似药:简介
  • 生物相似药:开发阶段
  • 生物相似药的授权相关法规必要条件
  • 生物相似药的开发与製造外包需求
  • 对全球受託製造市场的生物相似药的影响
  • 生物相似药受託製造服务供应商
  • 生物相似药製造业务的外包相关的课题

第11章 案例研究:低分子·高分子的医药品/治疗的比较

  • 章概要
  • 低分子·高分子医药品/治疗

第12章 案例研究:公司内部製造

  • 章概要
  • 公司内部製造
  • 生物医药品产业的外包趋势
  • 已批准生物製药所使用的製造方法
  • 恰当策略的选择:公司内部製造 vs. 外包

第13章 製造 vs. 购买的决策架构

第14章 大型製药公司的主张

第15章 伙伴关係和合作

第16章 M&A

第17章 最近的扩张

第18章 最近的发展

第19章 生产能力分析

第20章 需求分析

第21章 生物医药品受託製造组织的总持有成本

第22章 市场预测与机会分析

  • 章概要
  • 主要的前提条件与手法
  • 全球生物医药品受託製造市场(2022年~2035年)
  • 生物医药品受託製造市场 - 分析:各提供服务类型
  • 生物医药品受託製造市场 - 分析:製造的生物製药类别
  • 生物医药品受託製造市场 - 分析:所使用的表现系统类别
  • 生物医药品受託製造市场 - 分析:各产业规模
  • 生物医药品受託製造市场 - 分析:不同企业规模(2022年~2035年)
  • 生物医药品受託製造市场 - 分析:各地区

第23章 案例研究:虚拟製药企业

第24章 SWOT分析

第25章 生物医药品CMO市场未来

第26章 调查分析

第27章 结论

第28章 采访记录

第29章 附录I:表格形式的资料

第30章 附录II:企业/组织的清单

Product Code: RA100379

INTRODUCTION

Over the last few decades, the development landscape of small molecule drugs has been significantly impacted by various biotechnology breakthroughs. Further, with the advent of novel technologies, biologics have made a significant impact in the pharmaceutical domain, delivering ground-breaking treatment for a myriad of disease indications, including immunological, oncological and rare disorders. In this context, it is worth highlighting those 14 biopharmaceutical products (including cell therapies, gene therapies, monoclonal antibodies and recombinant proteins) were approved in the US alone, in 2021. Further, promising results from ongoing clinical research initiatives have encouraged various government and private firms to make significant investments in this domain. For instance, in 2021, a sum of over USD 70 billion was invested in the cell and gene therapy domain. However, manufacturing of biologics is fraught with various challenges. Some of the key concerns of contemporary innovators include rate of attrition of pipeline drugs / therapies, prolonged development timelines, current facility limitations, regulatory and compliance-related issues, and inconsistencies related to quality attributes of the final product. Therefore, therapy developers are actively exploring avenues that enable them to overcome the existing challenges. Amongst other alternatives, outsourcing has emerged as a lucrative option for biologic drug developers.

Currently, a significant number of players engaged in the biopharmaceutical domain prefer to outsource various operations to contract service providers. In fact, currently over 275 companies claim to offer contract manufacturing services for biologic therapeutics, in compliance with the regulatory standards. It is also worth highlighting that biopharmaceutical contract manufacturers are actively trying to consolidate their presence in this field by entering into strategic alliances in order to meet the indubitably rising demand for biologics. For this purpose, substantial expansions, and mergers and acquisitions have been reported in this market, as service providers strive to become one-stop-shops, to cater to the diverse needs of their clientele. With outsourcing being increasingly accepted as a viable and beneficial business model within this field, we anticipate the biopharmaceutical contract manufacturing market to grow at a commendable pace in the coming years.

SCOPE OF THE REPORT

The "Biopharmaceutical Contract Manufacturing Market by Type of Service(s) Offered (API, FDF), Type of Biologic Manufactured (Antibodies, Cell Therapies, Vaccines and Other Biologics), Type of Expression System Used (Mammalian, Microbial and Others), Scale of Operation (Preclinical / Clinical and Commercial), Company Size (Small, Mid-sized, and Large and Very Large), and Key Geographical Regions (North America, Europe, Asia-Pacific, Latin America and MENA): Industry Trends and Global Forecasts, 2022 - 2035" report features an extensive study of the current market landscape and the likely future potential associated with the biopharmaceutical contract manufacturing market, over the next decade.

The study also includes a detailed analysis of key drivers and trends within this evolving market. Amongst other elements, the report features:

  • A detailed overview of the overall landscape of companies engaged in offering contract manufacturing services for biologics, including a detailed analysis based on several relevant parameters, such as year of establishment, company size (based on number of employees), location of headquarters, type of service(s) offered (API and FDF manufacturing), type of biologic manufactured (ADCs, antibodies, biosimilars, cell therapies, gene therapies, nucleic acids / oligonucleotides, plasmid DNA / viral vectors, proteins / peptides, vaccines and others), scale of operation (preclinical, clinical and commercial), type of expression system used (mammalian, microbial and others), type of bioreactor used (single use, stainless steel and others) and mode of operation of bioreactor (batch, fed batch and perfusion / continuous).
  • A detailed landscape of the biopharmaceutical manufacturing facilities established across the key geographical regions (North America, Europe, Asia-Pacific and Rest of the World), highlighting the manufacturing hubs for biologics.
  • Elaborate profiles of key industry players based in North America, Europe and Asia-Pacific that offer contract manufacturing services for biologics. Each profile features a brief overview of the company, details related to its biologic-related service portfolio, manufacturing facilities, recent developments, and an informed future outlook.
  • A detailed discussion on the key enablers in this domain, including certain niche product classes, such as antibody drug conjugates (ADCs), bispecific antibodies, cell therapies, gene therapies and viral vectors, which are likely to have a significant impact on the growth of the contract services market.
  • A case study on the growing global biosimilars market, highlighting the associated opportunities for biopharmaceutical CMOs and CDMOs.
  • A case study comparing the key characteristics of small and large molecule drugs, along with details on the various steps involved in their respective manufacturing processes.
  • A detailed discussion on the benefits and challenges associated with in-house manufacturing, featuring a brief overview of the various parameters that a drug / therapy developer may need to take into consideration while deciding whether to manufacture its products in-house or outsource the production operations.
  • A qualitative analysis, highlighting various factors that need to be taken into consideration by biopharmaceutical developers while deciding whether to manufacture their respective products in-house or engage the services of a CMO.
  • A review of the various biopharmaceutical-focused manufacturing initiatives undertaken by top 10 big pharma players (shortlisted on the basis of 2021 revenues), highlighting trends across various parameters, such as number of initiatives, year of initiative, purpose of initiative, type of initiative, scale of operation and type of biologic manufactured.
  • An analysis of the recent collaborations within the biopharmaceutical contract manufacturing industry, based on several relevant parameters, such as year of partnership, type of partnership, type of biologic manufactured, therapeutic area, most active players (in terms of number of deals inked) and regional distribution of partnership activity that have taken place in this domain, during the period 2015-2022.
  • A detailed analysis of the various mergers and acquisitions that have taken place within this domain, during the period 2015-2022, based on several relevant parameters, such as year of agreement, type of deal, geographical location of companies, type of acquisition, type of biologic manufactured and key value drivers.
  • A detailed review of expansion initiatives undertaken by biopharmaceutical contract manufacturers, during the period 2016-2022, along with information on several relevant parameters, such as year of expansion, purpose of expansion, type of biologic manufactured and location of expanded facility.
  • An analysis of the recent developments within the biopharmaceutical contract manufacturing industry, highlighting information on the funding investments made during the period 2016-2022, along with information on the technology advancements related to biomanufacturing.
  • An estimate of the overall, installed capacity for the manufacturing of biopharmaceuticals, based on information reported by various industry stakeholders in the public domain, highlighting the distribution of the available capacity, based on size of manufacturer (small, mid-sized and large and very large), scale of operation (preclinical, clinical and commercial), type of expression system used (mammalian, microbial and others) and geography (North America, Europe, Asia-Pacific and Rest of the World).
  • An informed estimate of the annual demand for biologics, taking into account the top 20 biologics, based on various relevant parameters, such as target patient population, dosing frequency and dose strength of the abovementioned products.
  • A company size-wise, detailed analysis of the total cost of ownership for biopharmaceuticals contract manufacturing organizations, during the period 2022-2042.
  • A case study on the virtual business model concept, along with its role in the overall biopharmaceutical industry. It also features a discussion on the advantages and risks / challenges associated with outsourcing operations from virtual service providers.
  • A discussion on affiliated trends, key drivers and challenges, under an elaborate SWOT framework, which are likely to impact the industry's evolution, including a Harvey ball analysis, highlighting the relative effect of each SWOT parameter on the overall biopharmaceutical industry.
  • A survey analysis featuring inputs solicited from various experts who are directly / indirectly involved in providing contract manufacturing services to biopharmaceutical developers.

One of the key objectives of the report was to estimate the existing market size and estimate the future size of biopharmaceutical contract manufacturing market. We have provided informed estimates on the evolution of the market, over the period 2022-2035. Our year-wise projections of the current and future opportunity have further been segmented on the basis of [A] type of service(s) offered (API, FDF), [B] type of biologic manufactured (antibodies, cell therapies, vaccines and other biologics), [C] type of expression system used (mammalian, microbial and others), [D] scale of operation (preclinical / clinical and commercial), [E] company size (small, mid-sized, and large and very large), and [F] key geographical regions (North America, Europe, Asia-Pacific, Latin America and MENA).

In order to account for future uncertainties associated with some of the key parameters and to add robustness to our forecast model, we have provided three market forecast scenarios, portraying the conservative, base and optimistic tracks of the market's evolution.

All actual figures have been sourced and analyzed from publicly available information forums and primary research discussions. Financial figures mentioned in this report are in USD, unless otherwise specified.

KEY QUESTIONS ANSWERED

  • Who are the key players engaged in offering contract manufacturing services for biopharmaceuticals?
  • What are the different partnerships and expansion initiatives undertaken by biopharmaceutical contract manufacturers in the recent past?
  • Which regions represent the current key contract manufacturing hubs for biopharmaceuticals?
  • What is the current, installed capacity for contract manufacturing of biopharmaceuticals?
  • What is the current, global demand for biologics? How is the demand for such candidates likely to evolve in the foreseen future?
  • What percentage of the biopharmaceuticals manufacturing operations are presently outsourced?
  • What factors should be taken into consideration while deciding whether the manufacturing operations for biopharmaceuticals should be kept in-house or outsourced?
  • How is the current and future opportunity likely to be distributed across key market segments?

CHAPTER OUTLINES

Chapter 2 is an executive summary of key insights captured during our research. It offers a high-level view on the current state of biopharmaceutical contract manufacturing market and its likely evolution in the short to mid-term and long-term.

Chapter 3 provides a general introduction to biopharmaceuticals and biopharmaceutical manufacturing processes. The chapter also includes an overview of the various expression systems used for the development of different types of biotherapeutic products. It features a brief overview of contract manufacturing, along with a detailed discussion on the need for outsourcing within the biopharmaceutical industry. Furthermore, it provides information on the challenges faced by players currently engaged in this domain.

Chapter 4 provides a detailed assessment of the current market landscape of companies engaged in offering contract manufacturing services for biologics, including a detailed analysis based on several relevant parameters, such as year of establishment, company size (based on number of employees), location of headquarters, type of service(s) offered (API and FDF manufacturing), type of biologic manufactured (ADCs, antibodies, biosimilars, cell therapies, gene therapies, nucleic acids / oligonucleotides, plasmid DNA / viral vectors, proteins / peptides, vaccines and others), scale of operation (preclinical, clinical and commercial), type of expression system used (mammalian, microbial and others), type of bioreactor used (single use, stainless steel and others) and mode of operation of bioreactor (batch, fed batch and perfusion / continuous).

Chapter 5 provides a detailed landscape of the biopharmaceutical manufacturing facilities established across the key geographical regions (North America, Europe, Asia-Pacific and Rest of the World), highlighting the manufacturing hubs for biologics.

Chapter 6 provides elaborate profiles of key industry players based in North America that offer contract manufacturing services for biologics. Each profile features a brief overview of the company, details related to its biologic-related service portfolio, manufacturing facilities, recent developments, and an informed future outlook.

Chapter 7 provides elaborate profiles of key industry players based in Europe that offer contract manufacturing services for biologics. Each profile features a brief overview of the company, details related to its biologic-related service portfolio, manufacturing facilities, recent developments, and an informed future outlook.

Chapter 8 provides elaborate profiles of key industry players based in Asia-Pacific that offer contract manufacturing services for biologics. Each profile features a brief overview of the company, details related to its biologic-related service portfolio, manufacturing facilities, recent developments, and an informed future outlook.

Chapter 9 provides a detailed discussion on the key enablers in this domain, including certain niche product classes, such as antibody drug conjugates (ADCs), bispecific antibodies, cell therapies, gene therapies and viral vectors, which are likely to have a significant impact on the growth of the contract services market.

Chapter 10 presents a case study on the growing global biosimilars market, highlighting the associated opportunities for biopharmaceutical CMOs and CDMOs.

Chapter 11 presents a case study comparing the key characteristics of small and large molecule drugs, along with details on the various steps involved in their respective manufacturing processes.

Chapter 12 provides a detailed discussion on the benefits and challenges associated with in-house manufacturing, featuring a brief overview of the various parameters that a drug / therapy developer may need to take into consideration while deciding whether to manufacture its products in-house or outsource the production operations.

Chapter 13 presents a qualitative analysis, highlighting various factors that need to be taken into consideration by biopharmaceutical developers while deciding whether to manufacture their respective products in-house or engage the services of a CMO.

Chapter 14 provides a review of the various biopharmaceutical-focused manufacturing initiatives undertaken by top 10 big pharma players (shortlisted on the basis of 2021 revenues), highlighting trends across various parameters, such as number of initiatives, year of initiative, purpose of initiative, type of initiative, scale of operation and type of biologic manufactured.

Chapter 15 presents an analysis of the recent collaborations within the biopharmaceutical contract manufacturing industry, based on several relevant parameters, such as year of partnership, type of partnership, type of biologic manufactured, therapeutic area, most active players (in terms of number of deals inked) and regional distribution of partnership activity that have taken place in this domain, during the period 2015-2022.

Chapter 16 provides a detailed analysis of the various mergers and acquisitions that have taken place within this domain, during the period 2015-2022, based on several relevant parameters, such as year of agreement, type of deal, geographical location of companies, type of acquisition, type of biologic manufactured and key value drivers.

Chapter 17 presents a detailed review of expansion initiatives undertaken by biopharmaceutical contract manufacturers, during the period 2016-2022, along with information on several relevant parameters, such as year of expansion, purpose of expansion, type of biologic manufactured and location of expanded facility.

Chapter 18 presents an analysis of the recent developments within the biopharmaceutical contract manufacturing industry, highlighting information on the funding investments made during the period 2016-2022, along with information on the technology advancements related to biomanufacturing.

Chapter 19 provides an estimate of the overall, installed capacity for the manufacturing of biopharmaceuticals, based on information reported by various industry stakeholders in the public domain, highlighting the distribution of the available capacity, based on size of manufacturer (small, mid-sized, and large and very large), scale of operation (preclinical, clinical and commercial), type of expression system used (mammalian, microbial and others) and geography (North America, Europe, Asia-Pacific and Rest of the World).

Chapter 20 presents an informed estimate of the annual demand for biologics, taking into account the top 20 biologics, based on various relevant parameters, such as target patient population, dosing frequency and dose strength of the abovementioned products.

Chapter 21 presents a company size-wise, detailed analysis of the total cost of ownership for biopharmaceuticals contract manufacturing organizations, during the period 2022-2042.

Chapter 22 presents an insightful market forecast analysis, highlighting the future potential of biopharmaceutical contract manufacturing market till 2035. We have segmented the market on the basis of type of service(s) offered (API, FDF), type of biologic manufactured (antibodies, cell therapies, vaccines and other biologics), type of expression system used (mammalian, microbial and others), scale of operation (preclinical / clinical and commercial) , company size (small, mid-sized, and large and very large), and key geographical regions (North America, Europe, Asia-Pacific, Latin America and MENA).

Chapter 23 presents a case study on the virtual business model concept, along with its role in the overall biopharmaceutical industry. It also features a discussion on the advantages and risks / challenges associated with outsourcing operations from virtual service providers.

Chapter 24 provides a discussion on affiliated trends, key drivers and challenges, under an elaborate SWOT framework, which are likely to impact the industry's evolution, including a Harvey ball analysis, highlighting the relative effect of each SWOT parameter on the overall biopharmaceutical industry.

Chapter 25 features an elaborate discussion on the future opportunities / trends within the biopharmaceutical contract manufacturing market that are likely to influence the growth of this domain over the coming years.

Chapter 26 provides a survey analysis featuring inputs solicited from various experts who are directly / indirectly involved in providing contract manufacturing services to biopharmaceutical developers.

Chapter 27 is a summary of the entire report. It provides the key takeaways and presents our independent opinion of the biopharmaceutical contract manufacturing market, based on the research and analysis described in the previous chapters.

Chapter 28 is a collection of transcripts of interviews conducted with various stakeholders in the industry.

Chapter 29 is an appendix, which provides tabulated data and numbers for all the figures provided in the report.

Chapter 30 is an appendix, which provides the list of companies and organizations mentioned in the report.

TABLE OF CONTENTS

1. PREFACE

  • 1.1. Scope of the Report
  • 1.2. Market Segmentations
  • 1.3. Research Methodology
  • 1.4. Key Questions Answered
  • 1.5. Chapter Outlines

2. EXECUTIVE SUMMARY

  • 2.1. Chapter Overview

3. INTRODUCTION

  • 3.1. Chapter Overview
  • 3.2. Overview of Biopharmaceuticals
  • 3.3. Expression Systems for Biopharmaceuticals
    • 3.3.1. Insect Expression Systems
    • 3.3.2. Mammalian Expression Systems
    • 3.3.3. Microbial Expression Systems
      • 3.3.3.1. Bacterial Expression Systems
      • 3.3.3.2. Fungal Expression Systems
      • 3.3.3.3. Yeast Expression Systems
    • 3.3.4. Plant Expression Systems
    • 3.3.5. Mammalian versus Microbial Expression Systems
  • 3.4. Manufacturing Process of Biopharmaceuticals
    • 3.4.1. Upstream Processing
    • 3.4.2. Fermentation
    • 3.4.3. Downstream Processing
  • 3.5. Overview of Contract Manufacturing
  • 3.6. Need for Outsourcing Biopharmaceutical Manufacturing Operations
    • 3.6.1. Commonly Outsourced Manufacturing Operations for Biopharmaceuticals
    • 3.6.2. Advantages of Outsourcing Biopharmaceutical Manufacturing Operations
    • 3.6.3. Risks and Challenges Associated with Outsourcing Biopharmaceutical Manufacturing Operations
  • 3.7. Key Considerations While Selecting a Contract Manufacturing Partner
  • 3.8. Future Perspectives

4. MARKET LANDSCAPE

  • 4.1. Chapter Overview
  • 4.2. Biopharmaceutical Contract Manufacturers: Overall Market Landscape
    • 4.2.1. Analysis by Year of Establishment
    • 4.2.2. Analysis by Company Size
    • 4.2.3. Analysis by Location of Headquarters
    • 4.2.4. Analysis by Type of Service(s) Offered
    • 4.2.5. Analysis by Type of Biologic Manufactured
    • 4.2.6. Analysis by Scale of Operation
    • 4.2.7. Analysis by Type of Expression System Used
    • 4.2.8. Analysis by Type of Bioreactor Used
    • 4.2.9. Analysis by Mode of Operation of Bioreactor

5. REGIONAL CAPABILITY ANALYSIS

  • 5.1. Chapter Overview
  • 5.2. Key Assumptions and Methodology
  • 5.3. Overall Landscape of Biopharmaceutical Contract Manufacturing Facilities
    • 5.3.1. Analysis by Type of Service(s) Offered
    • 5.3.2. Analysis by Scale of Operation
    • 5.3.3. Analysis by Type of Expression System Used
  • 5.4. Regional Capability Analysis: Biopharmaceutical Contract Manufacturing Facilities in North America
  • 5.5. Regional Capability Analysis: Biopharmaceutical Contract Manufacturing Facilities in Europe
  • 5.6. Regional Capability Analysis: Biopharmaceutical Contract Manufacturing Facilities in Asia-Pacific and Rest of the World

6. BIOPHARMACEUTICAL CONTRACT MANUFACTURING IN NORTH AMERICA

  • 6.1. Chapter Overview
  • 6.2. Regulatory Scenario of Biopharmaceutical Contract Manufacturing in the US
  • 6.3. Leading Biopharmaceutical CMOs in North America
    • 6.3.1. AGC Biologics
      • 6.3.1.1. Company Overview
      • 6.3.1.2. Service Portfolio
        • 6.3.1.2.1. Process Development
        • 6.3.1.2.2. cGMP Manufacturing
        • 6.3.1.2.3. Quality and Regulatory
        • 6.3.1.2.4. Process Validation
      • 6.3.1.3. Financial Information
      • 6.3.1.4. Manufacturing Facilities
      • 6.3.1.5. Recent Developments and Future Outlook
    • 6.3.2. Catalent (Catalent Pharma Solutions)
      • 6.3.2.1. Company Overview
      • 6.3.2.2. Service Portfolio
        • 6.3.2.2.1. Cell Line Development
        • 6.3.2.2.2. Manufacturing (Biomanufacturing)
        • 6.3.2.2.3. ADCs and Bioconjugates Manufacturing
        • 6.3.2.2.4. Biosimilars Development and Manufacturing
        • 6.3.2.2.5. Proprietary Delivery and Fill / Finish Solutions
        • 6.3.2.2.6. Analytical Services
      • 6.3.2.3. Clinical Supply Services
      • 6.3.2.4. Financial Information
      • 6.3.2.5. Manufacturing Facilities
      • 6.3.2.6. Recent Developments and Future Outlook
    • 6.3.3. Cytiva (GE Healthcare)
      • 6.3.3.1. Company Overview
      • 6.3.3.2. Service Portfolio
        • 6.3.3.2.1. Biomanufacturing Services
        • 6.3.3.2.2. Scientific Support
        • 6.3.3.2.3. OptiRun Service Solutions
        • 6.3.3.2.4. Instruments Qualification Services
      • 6.3.3.3. Financial Information
      • 6.3.3.4. Manufacturing Facilities
      • 6.3.3.5. Recent Developments and Future Outlook
    • 6.3.4. FUJIFILM Diosynth Biotechnologies
      • 6.3.4.1. Company Overview
      • 6.3.4.2. Service Portfolio
        • 6.3.4.2.1. Strain Development
        • 6.3.4.2.2. Process Development
        • 6.3.4.2.3. GMP Contract Manufacturing
        • 6.3.4.2.4. Analytical Solutions
      • 6.3.4.3. Financial Information
      • 6.3.4.4. Manufacturing Facilities
      • 6.3.4.5. Recent Developments and Future Outlook
    • 6.3.5. KBI Biopharma
      • 6.3.5.1. Company Overview
      • 6.3.5.2. Service Portfolio
        • 6.3.5.2.1. Process Development
        • 6.3.5.2.2. Analytical Development
        • 6.3.5.2.3. GMP Manufacturing
        • 6.3.5.2.4. Clinical Cell Therapy Support
      • 6.3.5.3. Recent Developments and Future Outlook
    • 6.3.6. Patheon (acquired by Thermo Fisher Scientific)
      • 6.3.6.1 Company Overview
      • 6.3.6.2. Service Portfolio
        • 6.3.6.2.1. Biologics
          • 6.3.6.2.1.1. Drug Substance
        • 6.3.6.2.2. Analytical Services
        • 6.3.6.2.3. Product Development
        • 6.3.6.2.4. Commercial Product Supply
      • 6.3.6.3. Financial Information
      • 6.3.6.4. Manufacturing Facilities
      • 6.3.6.5. Recent Developments and Future Outlook
    • 6.3.7. Piramal Pharma Solutions
      • 6.3.7.1 Company Overview
      • 6.3.7.2. Service Portfolio
        • 6.3.7.2.1. Antibody Drug Conjugation Services
        • 6.3.7.2.2. Other Services
      • 6.3.7.3. Financial Information
      • 6.3.7.4. Manufacturing Facilities
      • 6.3.7.5. Recent Developments and Future Outlook

7. BIOPHARMACEUTICAL CONTRACT MANUFACTURING IN EUROPE

  • 7.1. Chapter Overview
  • 7.2. Biopharmaceutical Contract Manufacturing in Europe: Regulatory Scenario
    • 7.2.1. EMA's cGMP Regulations
  • 7.3. Leading Biopharmaceutical CMOs in Europe
    • 7.3.1. Boehringer Ingelheim (BioXcellence)
      • 7.3.1.1. Company Overview
      • 7.3.1.2. Service Portfolio
        • 7.3.1.2.1. Process Development
          • 7.3.1.2.1.1. Expression Systems
          • 7.3.1.2.1.2. Upstream Technology
          • 7.3.1.2.1.3. Downstream Technology
          • 7.3.1.2.1.4. Other Process Development Services
        • 7.3.1.2.2. Quality Assurance
        • 7.3.1.2.3. Fill / Finish
      • 7.3.1.3. Financial Information
      • 7.3.1.4. Manufacturing Facilities
      • 7.3.1.5. Recent Developments and Future Outlook
    • 7.3.2. Lonza
      • 7.3.2.1. Company Overview
      • 7.3.2.2. Service Portfolio
      • 7.3.2.3. Manufacturing Services
      • 7.3.2.4. Financial Information
      • 7.3.2.5. Manufacturing Facilities
      • 7.3.2.6. Recent Developments and Future Outlook
    • 7.3.3. Novasep
      • 7.3.3.1 Company Overview
      • 7.3.3.2. Service Portfolio
        • 7.3.3.2.1. Services for Viruses and Viral Vectors
        • 7.3.3.2.2. Services for Monoclonal Antibodies
        • 7.3.3.2.3. Services for ADCs
        • 7.3.3.2.4. Quality, Regulatory and Other Services
      • 7.3.3.3. Manufacturing Facilities
      • 7.3.3.4. Recent Developments and Future Outlook
    • 7.3.4. Olon
      • 7.3.4.1. Company Overview
      • 7.3.4.2. Service Portfolio
      • 7.3.4.3. Manufacturing Facilities
      • 7.3.4.4. Recent Developments and Future Outlook
    • 7.3.5. Rentschler Biopharma
      • 7.3.5.1. Company Overview
      • 7.3.5.2. Service Portfolio
        • 7.3.5.2.1. Bioprocess Development
        • 7.3.5.2.2. Biomanufacturing Services
        • 7.3.5.2.3. Other Services
      • 7.3.5.3. Manufacturing Facilities
      • 7.3.5.4. Recent Developments and Future Outlook
    • 7.3.6. Sandoz
      • 7.3.6.1. Company Overview
      • 7.3.6.2. Service Portfolio
      • 7.3.6.3. Financial Information
      • 7.3.6.4. Recent Developments and Future Outlook

8. BIOPHARMACEUTICAL CONTRACT MANUFACTURING IN ASIA-PACIFIC AND THE REST OF THE WORLD

  • 8.1. Chapter Overview
  • 8.2. Biopharmaceutical Contract Manufacturing in China
    • 8.2.1. Biopharmaceutical Contract Manufacturing in China: Regulatory Scenario
    • 8.2.2. Challenges Faced while Outsourcing to China
  • 8.3. Leading Biopharmaceutical CMOs in China
    • 8.3.1. WuXi Biologics
      • 8.3.1.1. Company Overview
      • 8.3.1.2. Service Portfolio
        • 8.3.1.2.1. Discovery Services
        • 8.3.1.2.2. Development Services
        • 8.3.1.2.3. Testing Services
        • 8.3.1.2.4. Clinical Manufacturing Services
        • 8.3.1.2.5. Fill / Finish Operations
      • 8.3.1.3. Financial Information
      • 8.3.1.4. Manufacturing Facilities
      • 8.3.1.5. Recent Developments and Future Outlook
  • 8.4. Biopharmaceutical Contract Manufacturing in India
    • 8.4.1. Biopharmaceutical Contract Manufacturing in India: Regulatory Scenario
    • 8.4.2. Challenges Faced while Outsourcing to India
  • 8.5. Leading Biopharmaceutical CMOs in India
    • 8.5.1. Kemwell Biopharma
      • 8.5.1.1. Company Overview
      • 8.5.1.2. Service Portfolio
        • 8.5.1.2.1. Development Services for Biopharmaceuticals
        • 8.5.1.2.2. Manufacturing Services for Biopharmaceuticals
      • 8.5.1.3. Manufacturing Facilities
      • 8.5.1.4. Recent Developments and Future Outlook
  • 8.6. Biopharmaceutical Contract Manufacturing in Japan
    • 8.6.1. Biopharmaceutical Contract Manufacturing in Japan: Regulatory Scenario
  • 8.7. Leading Biopharmaceutical CMOs in Japan
    • 8.7.1. Minaris Regenerative Medicine
      • 8.7.1.1. Company Overview
      • 8.7.1.2. Service Portfolio
        • 8.7.1.2.1. Manufacturing Development
        • 8.7.1.2.2. GMP Manufacturing
      • 8.7.1.3. Manufacturing Facilities
      • 8.7.1.4. Recent Developments and Future Outlook
    • 8.7.2. Takara Bio
      • 8.7.2.1. Company Overview
      • 8.7.2.2. Service Portfolio
      • 8.7.2.3. Financial Information
      • 8.7.2.4. Manufacturing Facilities
      • 8.7.2.5. Recent Developments and Future Outlook
  • 8.8. Biopharmaceutical Contract Manufacturing in South Korea
    • 8.8.1. Biopharmaceutical Contract Manufacturing in South Korea: Regulatory Scenario
  • 8.9. Leading Biopharmaceutical CMOs in South Korea
    • 8.9.1. Celltrion
      • 8.9.1.1. Company Overview
      • 8.9.1.2. Service Portfolio
      • 8.9.1.3. Financial Information
      • 8.9.1.4. Manufacturing Facilities
      • 8.9.1.5. Recent Developments and Future Outlook
    • 8.9.2. Samsung BioLogics
      • 8.9.2.1. Company Overview
      • 8.9.2.2. Service Portfolio
        • 8.9.2.2.1. Process Development
        • 8.9.2.2.2. Analytical Services
        • 8.9.2.2.3. cGMP Manufacturing Services
        • 8.9.2.2.4. Aseptic Fill / Finish
        • 8.9.2.2.5. Quality Services
        • 8.9.2.2.6. Other Services
      • 8.9.2.3. Financial Information
      • 8.9.2.4. Manufacturing Facilities
      • 8.9.2.5. Recent Developments and Future Outlook
  • 8.10. Biopharmaceutical Contract Manufacturing in Australia
    • 8.10.1. Biopharmaceutical Contract Manufacturing in Australia: Regulatory Scenario
  • 8.11. Leading Biopharmaceutical CMOs in Australia
    • 8.11.1. Cell Therapies
      • 8.11.1.1. Company Overview
      • 8.11.1.2. Service Portfolio
      • 8.11.1.3. Manufacturing Facilities
      • 8.11.1.4. Recent Developments and Future Outlook
    • 8.11.2. Luina Bio
      • 8.11.2.1. Company Overview
      • 8.11.2.2. Service Portfolio
        • 8.11.2.2.1. Microbial Products
        • 8.11.2.2.2. Vaccines
        • 8.11.2.2.3. Support Services
        • 8.11.2.2.4. Quality-related Services
      • 8.11.2.3. Manufacturing Facilities
      • 8.11.2.4. Recent Developments and Future Outlook

9. NICHE BIOPHARMACEUTICAL SECTORS

  • 9.1. Chapter Overview
  • 9.2. Bispecific Antibodies
    • 9.2.1. Introduction
    • 9.2.2. Pipeline Analysis
      • 9.2.2.1. Bispecific Antibody Therapeutics: Clinical Pipeline
      • 9.2.2.2. Bispecific Antibody Therapeutics: Early Stage Pipeline
      • 9.2.2.3. Multivalent Drug Candidates
    • 9.2.3. Analysis by Phase of Development
    • 9.2.4. Analysis by Target Indication
    • 9.2.5. Bispecific Antibody Therapeutics: List of Technology Providers
    • 9.2.6. Key Manufacturing Considerations and Challenges
    • 9.2.7. Contract Manufacturing Scenario
      • 9.2.7.1. CMOs Offering Services for Bispecific Antibodies
  • 9.3. Antibody Drug Conjugates (ADCs)
    • 9.3.1. Components of ADCs
      • 9.3.1.1. Antibody
      • 9.3.1.2. Cytotoxin
      • 9.3.1.3. Linker
    • 9.3.2. Manufacturing Process
    • 9.3.3. Pipeline Analysis
    • 9.3.4. Analysis by Phase of Development
    • 9.3.5. Analysis by Target Indication
    • 9.3.6. Key Technology Players: Analysis by Number of ADC Therapeutics
    • 9.3.7. Novel Drug Conjugates
    • 9.3.8. Key Manufacturing Considerations and Challenges
    • 9.3.9. Contract Manufacturing Scenario
      • 9.3.9.1. CMOs Offering Services for ADCs
  • 9.4. Cell Therapies
    • 9.4.1. Introduction
    • 9.4.2. Current Market Landscape
    • 9.4.3. Cell Therapy Manufacturing
      • 9.4.3.1. Cell Therapy Manufacturing Models
        • 9.4.3.1.1. Centralized Manufacturing
        • 9.4.3.1.2. Decentralized Manufacturing
    • 9.4.4. Key Manufacturing Considerations and Challenges
    • 9.4.5. Factors Influencing Cell Therapy Manufacturing
      • 9.4.5.1. Characterization
      • 9.4.5.2. Cost of Goods
      • 9.4.5.3. Automation of Cell Therapy Manufacturing
    • 9.4.6. Analysis by Types of Cells Manufactured
    • 9.4.7. Stem Cell Therapies: Analysis by Phase of Development
    • 9.4.8. T-Cell Therapies: Analysis by Phase of Development
    • 9.4.9. Contract Manufacturing Scenario
      • 9.4.9.1. CMOs Offering Services for Cell Therapy
  • 9.5. Gene Therapies
    • 9.5.1. Gene Therapies Market: Pipeline Analysis
      • 9.5.1.1. Analysis by Stage of Development
      • 9.5.1.2. Analysis by Phase of Development
      • 9.5.1.3. Analysis by Type of Vector Used
        • 9.5.1.3.1. Clinical Pipeline
        • 9.5.1.3.2. Preclinical Pipeline
      • 9.5.1.4. Analysis by Target Indication
        • 9.5.1.4.1. Clinical and Commercial Pipeline
        • 9.5.1.4.1. Preclinical Pipeline
      • 9.5.1.5. Analysis by Location of Manufacturing Facility
      • 9.5.1.6 Analysis by Type of Viral Vector Used
    • 9.5.2. Contract Manufacturing Scenario
      • 9.5.2.1. CMOs Offering Services for Viral Vectors
  • 9.6. Plasmid DNA
    • 9.6.1. Introduction
    • 9.6.2. Analysis by Location of Manufacturing Facility
    • 9.6.3. Contract Manufacturing Scenario
      • 9.6.3.1. CMOs Offering Services for Plasmid DNA

10. CASE STUDY: OUTSOURCING OF BIOSIMILARS

  • 10.1. Chapter Overview
  • 10.2. Biosimilars: An Introduction
  • 10.3. Biosimilars: Development Stages
  • 10.4. Regulatory Requirements for Licensing of Biosimilars
  • 10.5. Need for Outsourcing Biosimilar Development and Manufacturing
  • 10.6. Impact of Biosimilars on the Global Contract Manufacturing Market
    • 10.6.1. Biosimilars: Historical Trend of FDA Approval
  • 10.7. Biosimilars Contract Manufacturing Service Providers
  • 10.8. Challenges Associated with Outsourcing of Biosimilar Manufacturing Operations

11. CASE STUDY: COMPARISON OF SMALL AND LARGE MOLECULES DRUGS / THERAPIES

  • 11.1. Chapter Overview
  • 11.2. Small Molecule and Large Molecule Drugs / Therapies
    • 11.2.1. Comparison of General Characteristics
    • 11.2.2. Comparison of Key Specifications
    • 11.2.3. Comparison of Manufacturing Process
    • 11.2.4. Comparison of Key Manufacturing Challenges

12. CASE STUDY: IN-HOUSE MANUFACTURING

  • 12.1. Chapter Overview
  • 12.2. In-House Manufacturing
    • 12.2.1. Benefits Associated with In-House Manufacturing
    • 12.2.2. Risks Associated with In-House Manufacturing
  • 12.3. Outsourcing Trends in the Biopharmaceutical Industry
    • 12.3.1. Types of Outsourcing Partners
  • 12.4. Manufacturing Approaches Used for Approved Biologics, 2016-2022
    • 12.4.1. Approved Biologics: Analysis by Company Size and Type of Manufacturing Model Adopted
    • 12.4.2. Approved Biologics: Analysis by Company Size and Type of Biologic Manufactured
  • 12.5. Choosing the Right Strategy: In-House Manufacturing versus Outsourcing

13. MAKE VERSUS BUY DECISION MAKING FRAMEWORK

  • 13.1. Chapter Overview
  • 13.2. Assumptions and Key Parameters
  • 13.3. Biopharmaceutical Contract Manufacturers: Make versus Buy Decision Making
    • 13.3.1. Scenario 1
    • 13.3.2. Scenario 2
    • 13.3.3. Scenario 3
    • 13.3.4. Scenario 4
  • 13.4. Conclusion

14. BIG PHARMA INITIATIVES

  • 14.1. Chapter Overview
  • 14.2. Biopharmaceutical Related Initiatives of Big Pharmaceutical Players
    • 14.2.1. Analysis by Number of Initiatives
    • 14.2.2. Analysis by Year of Initiative
    • 14.2.3. Analysis by Purpose of Initiative
    • 14.2.4. Analysis by Type of Initiative
      • 14.2.4.1. Analysis by Type of Partnership
      • 14.2.4.2. Analysis by Type of Expansion
    • 14.2.5. Analysis by Scale of Operation
    • 14.2.6. Analysis by Type of Biologic Manufactured
    • 14.2.7. Analysis by Year of Initiative and Company
    • 14.2.8. Analysis by Purpose of Initiative and Company
    • 14.2.9. Analysis by Year and Type of Initiative
    • 14.2.10. Analysis by Region of Expansion and Company
    • 14.2.11. Analysis by Type of Biologic Manufactured and Company
  • 14.3. Competitive Benchmarking of Big Pharma Players

15. PARTNERSHIPS AND COLLABORATIONS

  • 15.1. Chapter Overview
  • 15.2. Partnership Models
  • 15.3. Biopharmaceutical Contract Manufacturing: Partnerships and Collaborations
    • 15.3.1. Analysis by Year of Partnership
    • 15.3.2. Analysis by Type of Partnership
    • 15.3.3. Analysis by Year and Type of Partnership
    • 15.3.4. Analysis by Type of Biologic Manufactured
    • 15.3.5. Analysis by Year of Partnership and Type of Biologic Manufactured
    • 15.3.6. Analysis by Type of Partnership and Type of Biologic Manufactured
    • 15.3.7. Analysis by Type of Biologic Manufactured and Geography
    • 15.3.8. Analysis by Therapeutic Area
    • 15.3.9. Most Active Players: Analysis by Number of Partnerships
    • 15.3.10. Analysis by Region
      • 15.3.10.1. Intracontinental and Intercontinental Agreements
      • 15.3.10.2. Local and International Agreements

16. MERGERS AND ACQUISITIONS

  • 16.1. Chapter Overview
  • 16.2. Merger and Acquisition Models
  • 16.3. Biopharmaceutical Contract Manufacturing: Mergers and Acquisitions
    • 16.3.1. Cumulative Year-wise Trend of Mergers and Acquisitions
    • 16.3.2. Analysis by Type of Acquisition
    • 16.3.3. Analysis by Region
      • 16.3.3.1. Mergers and Acquisitions: Continent-wise Distribution
      • 16.3.3.2. Mergers and Acquisitions: Country-wise Distribution
      • 16.3.3.3. Mergers and Acquisitions: Year-wise Trend in North America, Europe and Asia-Pacific
    • 16.3.4 Most Active Acquirers: Analysis by Number of Acquisitions
    • 16.3.5 Analysis by Key Value Drivers
    • 16.3.6. Analysis by Year of Acquisition and Key Value Drivers
    • 16.3.7. Analysis by Type of Biologic Manufactured
    • 16.3.8. Analysis by Key Value Drivers and Type of Biologic Manufactured
  • 16.4. Key Acquisitions: Deal Multiples
    • 16.4.1. Year-wise Trend of Deal Multiple Amount

17. RECENT EXPANSIONS

  • 17.1. Chapter Overview
  • 17.2. Biopharmaceutical Contract Manufacturing: Recent Expansions
    • 17.2.1. Analysis by Year of Expansion
    • 17.2.2. Analysis by Purpose of Expansion
    • 17.2.3. Analysis by Year and Purpose of Expansion
    • 17.2.4. Analysis by Type of Biologic Manufactured
    • 17.2.5. Analysis by Purpose of Expansion and Type of Biologic Manufactured
    • 17.2.6. Analysis by Location of Expanded Facility
    • 17.2.7. Most Active Players: Analysis by Number of Recent Expansions
    • 17.2.8. Analysis by Purpose of Expansion and Location of Expanded Facility
    • 17.2.9. Analysis by Amount Invested
    • 17.2.10. Recent Expansions: 2016-2020 and 2016-2022 Scenario

18. RECENT DEVELOPMENTS

  • 18.1. Chapter Overview
  • 18.2. Types of Funding
  • 18.3. Biopharmaceutical Contract Manufacturing: Funding and Investments
    • 18.3.1. Cumulative Year-wise Distribution by Number of Instances
    • 18.3.2. Cumulative Year-wise Distribution of Amount Invested
    • 18.3.3. Analysis of Instances by Type of Funding
    • 18.3.4. Analysis of Total Amount Invested by Type of Funding
    • 18.3.5. Analysis by Year and Type of Funding
    • 18.3.6. Regional Analysis of Total Amount Invested and Number of Funding Instances (Continent-wise)
    • 18.3.7. Regional Analysis of Total Amount Invested and Number of Funding Instances (Country-wise)
    • 18.3.8. Most Active Players: Analysis by Number of Funding Instances
    • 18.3.9. Most Active Players: Analysis by Total Amount Raised
    • 18.3.10. Most Active Investors: Analysis by Number of Funding Instances
  • 18.4. Technological Advancements
    • 18.4.1. Single Use Technology
    • 18.4.2. Process Analytical Technology (PAT)
    • 18.4.3. Continuous Processing
    • 18.4.4. Quality by Design (QbD) in Bio-Processing
    • 18.4.5. Modular / Podular Biopharma Facilities

19. CAPACITY ANALYSIS

  • 19.1. Chapter Overview
  • 19.2. Key Assumptions and Methodology
  • 19.3. Biopharmaceutical Contract Manufacturers: Global Production Capacity
    • 19.3.1. Analysis by Company Size
    • 19.3.2. Analysis by Type of Expression System Used
    • 19.3.3. Analysis by Scale of Operation
    • 19.3.4. Analysis by Region
      • 19.3.4.1. Analysis of Biopharmaceutical Contract Manufacturing Capacity in North America
      • 19.3.4.2. Analysis of Biopharmaceutical Contract Manufacturing Capacity in Europe
      • 19.3.4.3. Analysis of Biopharmaceutical Contract Manufacturing Capacity in Asia-Pacific
  • 19.4. Concluding Remarks

20. DEMAND ANALYSIS

  • 20.1. Chapter Overview
  • 20.2. Key Assumptions and Methodology
  • 20.3. Global Demand for Biopharmaceuticals
    • 20.3.1. Analysis by Therapeutic Area
  • 20.4. Relationship Between Annual Demand and Capacity
  • 20.5. Annual Demand for Emerging Novel Biologics
    • 20.5.1. ADC Therapeutics: Overall Annual Demand
    • 20.5.2. ADC Therapeutics: Demand and Supply Analysis
  • 20.6. Global Demand for Cell Therapy Manufacturing

21. TOTAL COST OF OWNERSHIP FOR BIOPHARMACEUTICAL CONTRACT MANUFACTURING ORGANIZATIONS

  • 21.1. Chapter Overview
  • 21.2. Key Parameters
  • 21.3. Assumptions and Methodology
  • 21.4. Total Cost of Ownership for Mid-sized Biopharmaceutical Contract Manufacturing Organizations, 2022-2042
  • 21.5. Total Cost of Ownership for Mid-sized Biopharmaceutical Contract Manufacturing Organizations: Analysis by CAPEX and OPEX, 2023-2042
    • 21.5.1. Total Cost of Ownership for Mid-sized Biopharmaceutical Contract Manufacturing Organizations: Analysis by CAPEX, 2023-2042
    • 21.5.2. Total Cost of Ownership for Mid-sized Biopharmaceutical Contract Manufacturing Organizations: Analysis by OPEX, 2023-2042

22. MARKET FORECAST AND OPPORTUNITY ANALYSIS

  • 22.1. Chapter Overview
  • 22.2. Key Assumptions and Methodology
  • 22.3. Global Biopharmaceutical Contract Manufacturing Market, 2022-2035
  • 22.4. Biopharmaceutical Contract Manufacturing Market: Analysis by Type of Service(s) Offered
    • 22.4.1. Biopharmaceutical Contract Manufacturing Market for APIs, 2022-2035
    • 22.4.2. Biopharmaceutical Contract Manufacturing Market for FDFs, 2022-2035
  • 22.5. Biopharmaceutical Contract Manufacturing Market: Analysis by Type of Biologic Manufactured
    • 22.5.1. Biopharmaceutical Contract Manufacturing Market for Antibodies, 2022-2035
    • 22.5.2. Biopharmaceutical Contract Manufacturing Market for Cell Therapies, 2022- 2035
    • 22.5.3. Biopharmaceutical Contract Manufacturing Market for Vaccines, 2022-2035
    • 22.5.4. Biopharmaceutical Contract Manufacturing Market for Other Biologics, 2022- 2035
  • 22.6. Biopharmaceutical Contract Manufacturing Market: Analysis by Type of Expression System Used
    • 22.6.1. Biopharmaceutical Contract Manufacturing Market for Mammalian Cell-based Operations, 2022-2035
    • 22.6.2. Biopharmaceutical Contract Manufacturing Market for Microbial Cell-based Operations, 2022-2035
    • 22.6.3. Biopharmaceutical Contract Manufacturing Market for Other Expression System- based Operations, 2022-2035
  • 22.7. Biopharmaceutical Contract Manufacturing Market: Analysis by Scale of Operation
    • 22.7.1. Biopharmaceutical Contract Manufacturing Market for Preclinical / Clinical Operations, 2022-2035
    • 22.7.2. Biopharmaceutical Contract Manufacturing Market for Commercial Operations, 2022-2035
  • 22.8. Biopharmaceutical Contract Manufacturing Market: Analysis by Company Size, 2022-2035
    • 22.8.1. Biopharmaceutical Contract Manufacturing Market for Small Companies, 2022- 2035
    • 22.8.2. Biopharmaceutical Contract Manufacturing Market for Mid-sized Companies, 2022-2035
    • 22.8.3. Biopharmaceutical Contract Manufacturing Market for Large and Very Large Companies, 2022-2035
  • 22.9. Biopharmaceutical Contract Manufacturing Market: Analysis by Geography
    • 22.9.1. Biopharmaceutical Contract Manufacturing Market in North America, 2022- 2035
      • 22.9.1.1. Biopharmaceutical Contract Manufacturing Market in the US, 2022-2035
      • 22.9.1.2. Biopharmaceutical Contract Manufacturing Market in Canada, 2022-2035
    • 22.9.2. Biopharmaceutical Contract Manufacturing Market in Europe, 2022-2035
      • 22.9.2.1. Biopharmaceutical Contract Manufacturing Market in Italy, 2022-2035
      • 22.9.2.2. Biopharmaceutical Contract Manufacturing Market in Germany, 2022-2035
      • 22.9.2.3. Biopharmaceutical Contract Manufacturing Market in France, 2022-2035
      • 22.9.2.4. Biopharmaceutical Contract Manufacturing Market in Spain, 2022-2035
      • 22.9.2.5. Biopharmaceutical Contract Manufacturing Market in the UK, 2022-2035
      • 22.9.2.6. Biopharmaceutical Contract Manufacturing Market in Rest of Europe, 2022-2035
    • 22.9.3. Biopharmaceutical Contract Manufacturing Market in Asia-Pacific, 2022-2035
      • 22.9.3.1. Biopharmaceutical Contract Manufacturing Market in China, 2022-2035
      • 22.9.3.2. Biopharmaceutical Contract Manufacturing Market in India, 2022-2035
      • 22.9.3.3. Biopharmaceutical Contract Manufacturing Market in South Korea, 2022-2035
      • 22.9.3.4. Biopharmaceutical Contract Manufacturing Market in Japan, 2022-2035
      • 22.9.3.5. Biopharmaceutical Contract Manufacturing Market in Rest of Asia-Pacific, 2022- 2035
    • 22.9.4. Biopharmaceutical Contract Manufacturing Market in Latin America, 2022-2035
    • 22.9.5. Biopharmaceutical Contract Manufacturing Market in Middle East and North Africa, 2022-2035

23. CASE STUDY: VIRTUAL PHARMACEUTICAL COMPANIES

  • 23.1. Chapter Overview
  • 23.2. Historical Evolution of the Virtual Business Model
  • 23.3. Virtual Pharmaceutical Companies as a Subset of the Overall Biopharmaceutical Industry
  • 23.4. Advantages Associated with Outsourcing Operations to Service Providers
  • 23.5. Key Challenges Associated with Outsourcing Operations to Service Providers

24. SWOT ANALYSIS

  • 24.1 Chapter Overview
  • 24.2. Strengths
  • 24.3. Weaknesses
  • 24.4. Opportunities
  • 24.5. Threats
  • 24.6. Comparison of SWOT Factors
  • 24.7. Conclusion

25. FUTURE OF THE BIOPHARMACEUTICAL CMO MARKET

  • 25.1. Chapter Overview
  • 25.2. Outsourcing Activities to Witness Significant Growth in the Coming Years
  • 25.3. Shift from One-time Contracts to Strategic Partnerships
  • 25.4. Integration / Adoption of Innovative Technologies
    • 25.4.1. Single use Bioreactors
    • 25.4.2. Novel Bioprocess Techniques
    • 25.4.3. Bioprocess Automation
  • 25.5. Focus on Niche Therapeutic Areas
  • 25.6. Growing Biosimilars Market to Contribute to the Growth of the Contract Services Segment
  • 25.7. Capability and Expertise Expansions by CMOs to become One-Stop-Shops
  • 25.8. Offshoring Outsourcing Activities to Maximize Profits and Expand Existing Capacities
  • 25.9. Increase in Financial Inflow and Outsourcing Budgets
  • 25.10. Challenges Faced by both Sponsors and Service Providers
    • 25.10.1. Concerns Related to Single Use Systems
    • 25.10.2. Issues Related to Capacity Fluctuations
  • 25.11. Concluding Remarks

26. SURVEY ANALYSIS

  • 26.1. Chapter Overview
    • 26.1.1. Overview of Respondents
    • 26.1.2. Analysis by Designation of Respondents
  • 26.2. Analysis by Biologic Manufacturing Expertise
  • 26.3. Analysis by Scale of Manufacturing
  • 26.4. Analysis by Location of Production Facilities
  • 26.5. Analysis by Type of Expression System Used
  • 26.6. Analysis by Type of Bioreactor Used
  • 26.7. Analysis by Mode of Operation of Bioreactor

27. CONCLUSION

  • 27.1. Chapter Overview

28. INTERVIEW TRANSCRIPTS

  • 28.1. Chapter Overview
  • 28.2. Andrea Conforto, Sales & Marketing, Bioservices Director, Olon
  • 28.3. Astrid Brammer, Key Account Manager, Richter Helm
  • 28.4. Birgit Schwab, Senior Manager Strategic Marketing, Rentschler Biotechnologie
  • 28.5. Christian Bailly, ex-Director of CDMO, Pierre Fabre
  • 28.6. Claire Otjes, Communication Manager, Batavia Biosciences
  • 28.7. David C Cunningham, Director Corporate Development, Goodwin Biotechnology
  • 28.8. Dietmar Katinger, Chief Executive Officer, Polymun Scientific
  • 28.9. Denis Angioletti, Chief Commercial Officer, Cerbios-Pharma
  • 28.10. Jeffrey Hung, General Manager, Vigene Biosciences
  • 28.11. Kevin Daley, Director Pharmaceuticals, Novasep
  • 28.12. Mark Wright, ex-Site Head, Grangemouth, Piramal Healthcare
  • 28.13. Max Rossetto, General Manager - Business Development, Luina Bio
  • 28.14. Nicolas Grandchamp, R&D Leader, GEG Tech
  • 28.15. Raquel Fortunato, Chief Executive Officer, GenIbet Biopharmaceuticals
  • 28.16. Sebastian Schuck, Head of Business Development, Wacker Biotech
  • 28.17. Tatjana Buchholz, Marketing Manager, Plasmid Factory and Marco Schmeer, ex- Project Manager
  • 28.18. Tim Oldham, ex- Chief Executive Officer, Cell Therapies
  • 28.19. Traci Kyes, Vice President of Commercial Operations, Arranta Bio
  • 28.20. Vijayakumar Ramaraj, Chief Manager, Shilpa Biologicals

29. APPENDIX I: TABULATED DATA

30. APPENDIX II: LIST OF COMPANIES AND ORGANIZATIONS

LIST OF TABLES

  • Table 3.1 Mammalian versus Microbial Expression Systems
  • Table 4.1 List of Biopharmaceutical Contract Manufacturers
  • Table 4.2 Biopharmaceutical Contract Manufacturers: Information on Type of Service(s) Offered
  • Table 4.3 Biopharmaceutical Contract Manufacturers: Information on Type of Biologic Manufactured
  • Table 4.4 Biopharmaceutical CMOs: Information on Scale of Operation
  • Table 4.5 Biopharmaceutical Contract Manufacturers: Information on Type of Expression System Used
  • Table 4.6 Biopharmaceutical Contract Manufacturers: Information on Type of Bioreactor Used
  • Table 4.7 Biopharmaceutical Contract Manufacturers: Information on Mode of Operation of Bioreactor
  • Table 5.1 List of Biopharmaceutical Contract Manufacturing Facilities in North America
  • Table 5.2 List of Biopharmaceutical Contract Manufacturing Facilities in Europe
  • Table 5.3 List of Biopharmaceutical Contract Manufacturing Facilities in Asia-Pacific and Rest of the World
  • Table 6.1 AGC Biologics: Company Overview
  • Table 6.2 AGC Biologics: Biologics Manufacturing Facilities
  • Table 6.3 AGC Biologics: Recent Developments and Future Outlook
  • Table 6.4 Catalent: Company Overview
  • Table 6.5 Catalent: Biologics Manufacturing Facilities
  • Table 6.6 Catalent: Recent Developments and Future Outlook
  • Table 6.7 Cytiva: Company Overview
  • Table 6.8 Cytiva: Manufacturing Facilities
  • Table 6.9 FUJIFILM Diosynth Biotechnologies: Company Overview
  • Table 6.10 FUJIFILM Diosynth Biotechnologies: Biopharmaceutical Facilities
  • Table 6.11 FUJIFILM Diosynth Biotechnologies: Recent Developments and Future Outlook
  • Table 6.12 KBI Biopharma: Company Overview,
  • Table 6.13 KBI Biopharma: Overview of Manufacturing Capabilities
  • Table 6.14 KBI Biopharma: Recent Developments and Future Outlook
  • Table 6.15 Patheon: Company Overview
  • Table 6.16 Patheon: Biopharmaceutical Manufacturing and Development Facilities
  • Table 6.17 Patheon: Future Outlook
  • Table 6.18 Piramal Pharma Solutions: Company Overview
  • Table 6.19 Piramal Pharma Solutions: Facilities
  • Table 6.20 Piramal Pharma Solutions: Recent Developments and Future Outlook
  • Table 7.1 FDA Quality Agreement and EMA cGMP Regulations: A Comparative Analysis
  • Table 7.2 Boehringer Ingelheim: Company Overview
  • Table 7.3 Boehringer Ingelheim: Biopharmaceutical Facilities
  • Table 7.4 Boehringer Ingelheim: Recent Developments and Future Outlook
  • Table 7.5 Lonza: Company Overview
  • Table 7.6 Lonza: Biopharmaceutical Facilities
  • Table 7.7 Lonza: Recent Developments and Future Outlook
  • Table 7.8 Novasep: Company Overview
  • Table 7.9 Novasep: Biologics Manufacturing Facilities
  • Table 7.10 Novasep: Recent Developments and Future Outlook
  • Table 7.11 Olon: Company Overview
  • Table 7.12 Olon: Biopharmaceutical Facilities
  • Table 7.13 Olon: Recent Developments and Future Outlook
  • Table 7.14 Rentschler Biopharma: Company Overview
  • Table 7.15 Rentschler Biopharma: Recent Developments and Future Outlook
  • Table 7.16 Sandoz: Company Overview
  • Table 8.1 WuXi Biologics: Company Overview
  • Table 8.2 WuXi Biologics: Recent Developments and Future Outlook
  • Table 8.3 Kemwell Biopharma: Company Overview
  • Table 8.4 Kemwell Biopharma: Recent Developments and Future Outlook
  • Table 8.5 Minaris Regenerative Medicine: Company Overview
  • Table 8.6 Minaris Regenerative Medicine: Manufacturing Facilities
  • Table 8.7 Minaris Regenerative Medicine: Recent Developments and Future Outlook
  • Table 8.8 Takara Bio: Company Overview
  • Table 8.9 Takara Bio: Biologics Manufacturing Facilities
  • Table 8.10 Takara Bio: Recent Developments and Future Outlook
  • Table 8.11 Celltrion: Company Overview
  • Table 8.12 Celltrion: Biologics Manufacturing Facilities
  • Table 8.13 Celltrion: Recent Developments and Future Outlook
  • Table 8.14 Samsung BioLogics: Company Overview
  • Table 8.15 Samsung BioLogics: Biopharmaceutical Facilities
  • Table 8.16 Samsung BioLogics: Recent Developments and Future Outlook
  • Table 8.17 Cell Therapies: Company Overview
  • Table 8.18 Cell Therapies: Recent Developments and Future Outlook
  • Table 8.19 Luina Bio: Company Overview
  • Table 8.20 Luina Bio: Recent Developments and Future Outlook
  • Table 9.1 Bispecific Antibody Therapeutics: Information on Developer(s), Platform / Technology Used, Phase of Development, Target Antigens and Antibody Format
  • Table 9.2 Bispecific Antibody Therapeutics: Information on Developer(s), Technology Used, Phase of Development, Target Antigens, Mechanism of Action, Disease Indication, Therapeutic Area and Broader Disease Segment
  • Table 9.3 List of Other Emerging Multivalent Drug Candidates
  • Table 9.4 Bispecific Antibody Therapeutics: List of Technology Platforms
  • Table 9.5 Bispecific Antibody Contract Manufacturers: List of Companies
  • Table 9.6 Commonly Used Cytotoxins for ADC Therapeutics
  • Table 9.7 Occupational Exposure Limit Bands, Safebridge Consultants
  • Table 9.8 Antibody Drug Conjugates: Drug Pipeline
  • Table 9.9 Novel Drug Conjugates: List of Developers
  • Table 9.10 ADC Contract Manufacturers: List of Companies
  • Table 9.11 Applications of Cell-based Therapies
  • Table 9.12 Cell-based Therapies: Commercialized Products,
  • Table 9.13 Assessments for Key Cell Therapy Manufacturing Steps
  • Table 9.14 Advantages and Disadvantages of Centralized and Decentralized Manufacturing Models
  • Table 9.15 Cell Therapy Manufacturing (Industry Players): Information on Type of Cell Manufactured
  • Table 9.16 Cell Therapy Contract Manufacturers: List of Cell Therapy Contract Manufacturers
  • Table 9.17 Cell Therapy Contract Manufacturers: List of Non-Industry Players
  • Table 9.18 Viral Vectors Manufacturers: Information on Type of Viral Vector Used
  • Table 9.19 Viral Vectors Contract Manufacturers: List of Companies,
  • Table 9.20 Plasmid DNA Contract Manufacturers: List of Companies
  • Table 10.1 List of Biosimilars Contract Manufacturing Service Providers
  • Table 11.1 Small Molecules and Large Molecules: Strengths and Weaknesses
  • Table 11.2 Small Molecules and Large Molecules: Comparison of Key Characteristics
  • Table 11.3 Small Molecules and Large Molecules: Comparison of Development Characteristics
  • Table 12.1 List of FDA Approved Biologics (2016-2022)
  • Table 14.1 Big Pharma Players: List of Biopharmaceutical Manufacturing Initiatives
  • Table 15.1 Biopharmaceutical Contract Manufacturing: List of Partnerships and Collaborations, 2015-2022
  • Table 15.2 Partnerships and Collaborations: Information on Type of Biologic Manufactured
  • Table 16.1 Biopharmaceutical Contract Manufacturing: List of Mergers and Acquisitions, 2015-2022
  • Table 16.2 Biopharmaceutical Contract Manufacturing Mergers and Acquisitions: Information on Key Value Drivers and Type of Biologic Manufactured, 2015- 2022
  • Table 16.3 Mergers and Acquisitions: Information on Deal Multiples, 2015-2022
  • Table 17.1 Biopharmaceutical Contract Manufacturing: List of Recent Expansions
  • Table 18.1 Biopharmaceutical Contract Manufacturing Market: Funding and Investment
  • Table 18.2 Funding and Investment Analysis: Summary of Investments
  • Table 18.3 Funding and Investment Analysis: Summary of Venture Capital Funding
  • Table 19.1 Capacity Analysis: Information on Contract Biomanufacturing Capacity
  • Table 19.2 Capacity Analysis: Average Capacity per Category (Sample Data Set)
  • Table 19.3 Capacity Analysis: Average Capacity for Mammalian Expression System (Sample Data Set)
  • Table 19.4 Capacity Analysis: Average Capacity for Microbial Expression System (Sample Data Set)
  • Table 19.5 Capacity Analysis: Global Contract Biomanufacturing Capacity
  • Table 20.1 Annual Biomanufacturing Capacity, 2022-2035 (Million Liters)
  • Table 20.2 ADC Therapeutics: Annual Demand for Outsourcing, 2022-2030 (in kilograms)
  • Table 20.3 ADC Therapeutics: Annual Supply for Outsourcing, 2022-2030 (in kilograms)
  • Table 23.1 List of Virtual Biopharmaceutical Companies
  • Table 24.1 Global Biopharmaceuticals Market: Patent Approval and Expiry Details of Best- selling Biologics
  • Table 26.1 Survey Analysis: Overview of Respondents
  • Table 26.2 Survey Analysis: Distribution of Respondents by Designation
  • Table 26.3 Survey Analysis: Biologics Manufacturing Expertise
  • Table 26.4 Survey Analysis: Scale of Manufacturing
  • Table 26.5 Survey Analysis: Location of Production Facilities
  • Table 26.6 Survey Analysis: Type of Expression System Used
  • Table 26.7 Survey Analysis: Type of Bioreactor Used
  • Table 26.8 Survey Analysis: Mode of Operation of Bioreactor
  • Table 29.1 Biopharmaceutical CMOs: Distribution by Year of Establishment
  • Table 29.2 Biopharmaceutical CMOs: Distribution by Company Size
  • Table 29.3 Biopharmaceutical CMOs: Distribution by Location of Headquarters (Region- wise)
  • Table 29.4 Biopharmaceutical CMOs: Distribution by Location of Headquarters (Country- wise)
  • Table 29.5 Biopharmaceutical CMOs: Distribution by Company Size, Year of Establishment and Location of Headquarters
  • Table 29.6 Biopharmaceutical CMOs: Distribution by Type of Service(s) Offered
  • Table 29.7 Biopharmaceutical CMOs: Distribution by Type of Biologic Manufactured
  • Table 29.8 Biopharmaceutical CMOs: Distribution by Type of Biologic Manufactured and Location of Headquarters
  • Table 29.9 Biopharmaceutical CMOs: Distribution by Type of Biologic Manufactured and Company Size
  • Table 29.10 Biopharmaceutical CMOs: Distribution by Scale of Operation
  • Table 29.11 Biopharmaceutical CMOs: Distribution by Type of Biologic Manufactured and Scale of Operation
  • Table 29.12 Biopharmaceutical CMOs: Distribution by Type of Expression System Used
  • Table 29.13 Biopharmaceutical CMOs: Distribution by Type of Expression System Used and Location of Headquarters
  • Table 29.14 Biopharmaceutical CMOs: Distribution by Type of Bioreactor Used
  • Table 29.15 Biopharmaceutical CMOs: Distribution by Mode of Operation of Bioreactor
  • Table 29.16 Regional Distribution of Biopharmaceutical Contract Manufacturing Facilities
  • Table 29.17 Biopharmaceutical Contract Manufacturing Facilities: Distribution of Type of Service(s) Offered
  • Table 29.18 Biopharmaceutical Contract Manufacturing Facilities: Distribution by Scale of Operation
  • Table 29.19 Biopharmaceutical Contract Manufacturing Facilities: Distribution by Type of Expression System Used
  • Table 29.20 AGC Biologics: Annual Revenues FY 2017-Q1 2022 (JPY Billion)
  • Table 29.21 Catalent: Annual Revenues, FY 2017-9M 2022 (USD Million)
  • Table 29.22 Cytiva: Annual Revenues, FY 2017-FY 2021 (USD Million)
  • Table 29.23 FUJIFILM Diosynth Biotechnologies: Annual Revenues, FY 2017-FY 2021 (JPY Billion)
  • Table 29.24 FUJIFILM Holdings: Annual Revenues by Business Divisions (JPY Billion)
  • Table 29.25 Patheon: Annual Revenues, FY 2017-FY 2021 (USD Million)
  • Table 29.26 Piramal Enterprises: Annual Revenues, FY 2017-FY 2021 (INR Crores)
  • Table 29.27 Boehringer Ingelheim: Annual Revenues, FY 2017-FY 2021 (EUR Billion)
  • Table 29.28 Lonza: Annual Revenues, FY 2017-FY 2021 (CHF Billion)
  • Table 29.29 Lonza: Annual Revenues by Business Divisions (CHF Billion)
  • Table 29.30 Sandoz: Annual Revenues, FY 2017-Q1 2022 (USD Billion)
  • Table 29.31 WuXi Biologics: Annual Revenues, FY 2017-FY 2021 (RMB Million)
  • Table 29.32 Takara Bio: Annual Revenues, FY 2017-FY 2021 (JPY Million)
  • Table 29.33 Celltrion: Annual Revenues, FY 2017-Q1 2022 (KRW Billion)
  • Table 29.34 Samsung Biologics: Annual Revenues, FY 2017-Q1 2022 (KRW Billion)
  • Table 29.35 Bispecific Antibody Therapeutics Pipeline: Distribution by Phase of Development
  • Table 29.36 Bispecific Antibody Therapeutics Pipeline: Distribution by Target Indication
  • Table 29.37 Antibody Drug Conjugates: Distribution by Status of Development
  • Table 29.38 Antibody Drug Conjugates: Distribution by Target Indication
  • Table 29.39 Key ADC Technology Providers: Distribution by Number of Candidates
  • Table 29.40 Stem Cell Therapies: Distribution by Phase of Development
  • Table 29.41 T-Cell Therapies: Distribution by Phase of Development
  • Table 29.42 Gene Therapies: Distribution by Stage of Development
  • Table 29.43 Gene Therapies: Distribution by Phase of Development
  • Table 29.44 Clinical and Commercial Pipeline of Gene Therapies: Distribution by Type of Vector Used
  • Table 29.45 Early-Stage Pipeline of Gene Therapies: Distribution by Type of Vector Used
  • Table 29.46 Clinical and Commercial Pipeline of Gene Therapies: Distribution by Therapeutic Area
  • Table 29.47 Early-Stage Pipeline of Gene Therapies: Distribution by Therapeutic Area
  • Table 29.48 Viral Vector Manufacturers: Distribution by Location of Manufacturing Facility
  • Table 29.49 Plasmid DNA Manufacturers: Distribution by Location of Manufacturing Facility
  • Table 29.50 Biosimilars: Historical Trend of FDA Approval, 2015-2021
  • Table 29.51 Small Molecule and Large Molecule Drugs: Historical Trend of FDA Approval, 2005-2021
  • Table 29.52 Big Pharma Players: Distribution by Number of Biopharmaceutical Contract Manufacturing Focused Initiatives, 1980-2022
  • Table 29.53 Big Pharma Players: Cumulative Distribution by Year of Initiative
  • Table 29.54 Big Pharma Players: Distribution by Purpose of Initiative
  • Table 29.55 Big Pharma Players: Distribution by Type of Initiative
  • Table 29.56 Big Pharma Players: Distribution by Type of Expansion
  • Table 29.57 Big Pharma Players: Distribution by Scale of Operation
  • Table 29.58 Big Pharma Players: Distribution by Type of Biologic Manufactured
  • Table 29.59 Big Pharma Players: Distribution by Purpose of Initiative and Company
  • Table 29.60 Big Pharma Players: Distribution by Year and Type of Initiative
  • Table 29.61 Big Pharma Players: Distribution by Region of Expansion and Company
  • Table 29.62 Partnerships and Collaborations: Cumulative Year-wise Trend, 2015-2022
  • Table 29.63 Partnerships and Collaborations: Distribution by Type of Partnership
  • Table 29.64 Partnerships and Collaborations: Distribution by Type of Biologic Manufactured
  • Table 29.65 Partnerships and Collaborations: Distribution by Year of Partnership and Type of Biologic Manufactured
  • Table 29.66 Partnerships and Collaborations: Distribution by Type of Biologic Manufactured and Geography
  • Table 29.67 Partnerships and Collaborations: Distribution by Therapeutic Area
  • Table 29.68 Most Active Players: Distribution by Number of Partnerships
  • Table 29.69 Partnerships and Collaborations: Local and International Agreements
  • Table 29.70 Mergers and Acquisitions: Cumulative Year-Wise Trend (2015-2022)
  • Table 29.71 Mergers and Acquisitions: Distribution by Type of Acquisition
  • Table 29.72 Mergers and Acquisitions: Distribution by Region (Continent-wise)
  • Table 29.73 Mergers and Acquisitions: Distribution by Region (Country-wise)
  • Table 29.74 Mergers and Acquisitions: Year-Wise Trend in North America, Europe and Asia- Pacific (2015-2022)
  • Table 29.75 Most Active Acquirers: Distribution by Number of Acquisitions
  • Table 29.76 Mergers and Acquisitions: Distribution by Key Value Drivers
  • Table 29.77 Mergers and Acquisitions: Distribution by Year of Acquisition and Key Value Drivers
  • Table 29.78 Mergers and Acquisitions: Distribution by Type of Biologic Manufactured
  • Table 29.79 Mergers and Acquisitions: Distribution by Key Value Drivers and Type of Biologic Manufactured
  • Table 29.80 Mergers and Acquisitions: Year-wise Trend of Deal Multiple Amount (USD Million)
  • Table 29.81 Recent Expansions: Cumulative Year-wise Trend, 2016-2022
  • Table 29.82 Recent Expansions: Distribution by Purpose of Expansion
  • Table 29.83 Recent Expansions: Distribution by Year and Purpose of Expansion
  • Table 29.84 Recent Expansions: Distribution by Type of Biologic Manufactured
  • Table 29.85 Recent Expansions: Distribution by Purpose of Expansion and Type of Biologic Manufactured
  • Table 29.86 Recent Expansions: Distribution by Location of Expanded Facility
  • Table 29.87 Most Active Players: Distribution by Number of Recent Expansions
  • Table 29.88 Recent Expansions: Distribution by Location of Headquarters and Purpose of Expansion
  • Table 29.89 Recent Expansions: Distribution by Amount Invested (USD Million)
  • Table 29.90 Funding and Investment Analysis: Cumulative Year-wise Trend of Number of Funding Instances, 2016-2022
  • Table 29.91 Funding and Investment Analysis: Cumulative Year-wise Trend of Total Amount Invested, 2016-2022 (USD Million)
  • Table 29.92 Funding and Investment Analysis: Distribution of Number of Funding Instances by Type of Funding
  • Table 29.93 Funding and Investment Analysis: Distribution of Total Amount Invested by Type of Funding (USD Million)
  • Table 29.94 Funding and Investment Analysis: Distribution by Year and Type of Funding, 2016-2022
  • Table 29.95 Funding and Investment Analysis: Distribution of Number of Funding Instances and Total Amount Invested by Geography (Continent-wise) (USD Million)
  • Table 29.96 Funding and Investment Analysis: Distribution of Number of Funding Instances and Total Amount Invested by Geography (Country-wise) (USD Million)
  • Table 29.97 Most Active Players: Distribution by Number of Funding Instances
  • Table 29.98 Most Active Players: Distribution by Total Amount Raised (USD Million)
  • Table 29.99 Most Active Investors: Distribution by Number of Funding Instances
  • Table 29.100 Capacity Analysis: Distribution by Company Size
  • Table 29.101 Capacity Analysis: Distribution by Type of Expression System Used
  • Table 29.102 Capacity Analysis: Distribution by Scale of Operation
  • Table 29.103 Capacity Analysis: Distribution by Region
  • Table 29.104 Capacity Analysis: Biopharmaceutical Contract Manufacturing Capacity in North America
  • Table 29.105 Capacity Analysis: Biopharmaceutical Contract Manufacturing Capacity in Europe
  • Table 29.106 Capacity Analysis: Biopharmaceutical Contract Manufacturing Capacity in Asia- Pacific
  • Table 29.107 Global Demand for Biopharmaceuticals, 2022-2035 (in kilograms)
  • Table 29.108 Demand Analysis: Distribution of Annual Demand by Therapeutic Area
  • Table 29.109 Demand and Supply Scenario for Biopharmaceuticals, 2022-2035 (Million Liters)
  • Table 29.110 Demand Analysis: Annual Demand for ADC Therapeutics (in kilograms), 2022- 2030
  • Table 29.111 Global Demand for Cell Therapies, 2022-2030 (in terms of Number of Patients)
  • Table 29.112 Global Demand for Cell Therapies, 2022-2030 (Billion Cells)
  • Table 29.113 Total Cost of Ownership for Mid-sized Biopharmaceutical Contract Manufacturing Organizations, 2022-2042 (USD Million)
  • Table 29.114 Total Cost of Ownership for Mid-sized Biopharmaceutical Contract Manufacturing Organizations: Distribution by CAPEX and OPEX, 2023 and 2042 (USD Million)
  • Table 29.115 Total Cost of Ownership for Mid-sized Biopharmaceutical Contract Manufacturing Organizations, 2023: Distribution of CAPEX (USD Million)
  • Table 29.116 Total Cost of Ownership for Mid-sized Biopharmaceutical Contract Manufacturing Organizations, 2023-2042: Distribution by OPEX (USD Million)
  • Table 29.117 Global Biopharmaceutical Contract Manufacturing Market, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.118 Biopharmaceutical Contract Manufacturing Market: Distribution by Type of Service(s) Offered, 2022 and 2035
  • Table 29.119 Biopharmaceutical Contract Manufacturing Market for APIs, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.120 Biopharmaceutical Contract Manufacturing Market for FDFs, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.121 Biopharmaceutical Contract Manufacturing Market: Distribution by Type of Biologic Manufactured
  • Table 29.122 Biopharmaceutical Contract Manufacturing Market for Antibodies, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.123 Biopharmaceutical Contract Manufacturing Market for Cell Therapies, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.124 Biopharmaceutical Contract Manufacturing Market for Vaccines, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.125 Biopharmaceutical Contract Manufacturing Market for Other Biologics, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.126 Biopharmaceutical Contract Manufacturing Market: Distribution by Type of Expression System Used
  • Table 29.127 Biopharmaceutical Contract Manufacturing Market for Mammalian Cell-based Operations, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.128 Biopharmaceutical Contract Manufacturing Market for Microbial Cell-based Operations, Conservative, Base and Optimistic Scenarios 2022-2035 (USD Billion)
  • Table 29.129 Biopharmaceutical Contract Manufacturing Market for Other Expression System- based Operations, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.130 Biopharmaceutical Contract Manufacturing Market: Distribution by Scale of Operation
  • Table 29.131 Biopharmaceutical Contract Manufacturing Market for Preclinical / Clinical Operations, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.132 Biopharmaceutical Contract Manufacturing Market for Commercial Operations, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.133 Biopharmaceutical Contract Manufacturing Market: Distribution by Company Size
  • Table 29.134 Biopharmaceutical Contract Manufacturing Market for Small Companies, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.135 Biopharmaceutical Contract Manufacturing Market for Mid-sized Companies, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.136 Biopharmaceutical Contract Manufacturing Market for Large and Very Large Companies, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.137 Biopharmaceutical Contract Manufacturing Market: Distribution by Geography
  • Table 29.138 Biopharmaceutical Contract Manufacturing Market in North America, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.139 Biopharmaceutical Contract Manufacturing Market in the US, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.140 Biopharmaceutical Contract Manufacturing Market in Canada, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.141 Biopharmaceutical Contract Manufacturing Market in Europe, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.142 Biopharmaceutical Contract Manufacturing Market in Italy, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.143 Biopharmaceutical Contract Manufacturing Market in Germany, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.144 Biopharmaceutical Contract Manufacturing Market in France, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.145 Biopharmaceutical Contract Manufacturing Market in Spain, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.146 Biopharmaceutical Contract Manufacturing Market in the UK, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.147 Biopharmaceutical Contract Manufacturing Market in Rest of Europe, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.148 Biopharmaceutical Contract Manufacturing Market in Asia-Pacific, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.149 Biopharmaceutical Contract Manufacturing Market in China, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.150 Biopharmaceutical Contract Manufacturing Market in India, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.151 Biopharmaceutical Contract Manufacturing Market in South Korea, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.152 Biopharmaceutical Contract Manufacturing Market in Japan, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.153 Biopharmaceutical Contract Manufacturing Market in Rest of Asia-Pacific, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.154 Biopharmaceutical Contract Manufacturing Market in Latin America, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.155 Biopharmaceutical Contract Manufacturing Market in Middle East and North Africa, Conservative, Base and Optimistic Scenarios, 2022-2035 (USD Billion)
  • Table 29.156 Overall Share of Virtual Biopharmaceutical Companies in the Biopharmaceutical Market in 2022 (USD Billion)
  • Table 29.157 Global Biopharmaceuticals Market: Distribution of Number of FDA Approvals by Year, 2005-2022
  • Table 29.158 Survey Analysis: Distribution of Respondents by Company Type
  • Table 29.159 Survey Analysis: Distribution of Respondents by Location of Headquarters
  • Table 29.160 Survey Analysis: Distribution of Respondents by Designation
  • Table 29.161 Survey Analysis: Distribution by Biologics Manufacturing Expertise
  • Table 29.162 Survey Analysis: Distribution by Scale of Manufacturing
  • Table 29.163 Survey Analysis: Distribution by Location of Production Facilities
  • Table 29.164 Survey Analysis: Distribution by Type of Expression System Used
  • Table 29.168 Survey Analysis: Distribution by Mode of Operation of Bioreactor

LIST OF FIGURES

  • Figure 2.1 Executive Summary: Overall Market Landscape
  • Figure 2.2 Executive Summary: Partnerships and Collaborations
  • Figure 2.3 Executive Summary: Mergers and Acquisitions
  • Figure 2.4 Executive Summary: Recent Expansions
  • Figure 2.5 Executive Summary: Demand Analysis
  • Figure 2.6 Executive Summary: Market Forecast and Opportunity Analysis
  • Figure 3.1 Types of Biopharmaceuticals
  • Figure 3.2 Types of Expression Systems Used for the Production of Biopharmaceuticals
  • Figure 3.3 Stages of the Biomanufacturing Process
  • Figure 3.4 Types of Third-Party Service Providers
  • Figure 3.5 Commonly Outsourced Biopharmaceutical Contract Manufacturing Operations
  • Figure 4.1 Biopharmaceutical Contract Manufacturers: Distribution by Year of Establishment
  • Figure 4.2 Biopharmaceutical Contract Manufacturers: Distribution by Company Size
  • Figure 4.3 Biopharmaceutical Contract Manufacturers: Distribution by Location of Headquarters (Region-wise)
  • Figure 4.4 Biopharmaceutical Contract Manufacturers: Distribution by Location of Headquarters (Country-wise)
  • Figure 4.5 Biopharmaceutical Contract Manufacturers: Distribution by Company Size, Year of Establishment and Location of Headquarters
  • Figure 4.6 Biopharmaceutical CMOs: Distribution by Type of Service(s) Offered
  • Figure 4.7 Biopharmaceutical CMOs: Distribution by Type of Biologic Manufactured
  • Figure 4.8 Biopharmaceutical Contract Manufacturers: Distribution by Type of Biologic Manufactured and Location of Headquarters
  • Figure 4.9 Biopharmaceutical Contract Manufacturers: Distribution by Type of Biologic Manufactured and Company Size
  • Figure 4.10 Biopharmaceutical Contract Manufacturers: Distribution by Scale of Operation
  • Figure 4.11 Biopharmaceutical Contract Manufacturers: Distribution by Type of Biologic Manufactured and Scale of Operation
  • Figure 4.12 Biopharmaceutical Contract Manufacturers: Distribution by Type of Expression System Used
  • Figure 4.13 Biopharmaceutical Contract Manufacturers: Distribution by Types of Expression Systems Used and Location of Headquarters
  • Figure 4.14 Biopharmaceutical Contract Manufacturers: Distribution by Type of Bioreactor Used
  • Figure 4.15 Biopharmaceutical Contract Manufacturers: Distribution by Mode of Operation of Bioreactor
  • Figure 5.1 Regional Distribution of Biopharmaceutical Contract Manufacturing Facilities
  • Figure 5.2 Biopharmaceutical Contract Manufacturing Facilities: Distribution by Type of Service(s) Offered
  • Figure 5.3 Biopharmaceutical Contract Manufacturing Facilities: Distribution by Scale of Operation
  • Figure 5.4 Biopharmaceutical Contract Manufacturing Facilities: Distribution by Type of Expression System Used
  • Figure 5.5 Regional Capability Analysis: Biopharmaceutical Contract Manufacturers in North America
  • Figure 5.6 Regional Capability Analysis: Biopharmaceutical Contract Manufacturers in Europe
  • Figure 5.7 Regional Capability Analysis: Biopharmaceutical Contract Manufacturers in Asia-Pacific and Rest of the World
  • Figure 6.1 Biopharmaceutical Industry: The US Market Scenario
  • Figure 6.2 Biopharmaceutical Contract Manufacturing in the US: Growth Drivers and Challenges
  • Figure 6.3 US FDA Guidelines: Elements of a Quality Agreement
  • Figure 6.4 US FDA Guidelines: Key Considerations for Biologic Manufacturing Operations
  • Figure 6.5 AGC Biologics: Annual Revenues, FY 2017-Q1 2022 (JPY Billion)
  • Figure 6.6 Catalent: Service Portfolio
  • Figure 6.7 Catalent: Biosimilars Service Portfolio
  • Figure 6.8 Catalent: Annual Revenues, FY 2017-9M 2022 (USD Million)
  • Figure 6.9 Cytiva: Service Portfolio
  • Figure 6.10 Cytiva: Annual Revenues, FY 2017-FY 2021 (USD Million)
  • Figure 6.11 FUJIFILM Diosynth Biotechnologies: Service Portfolio
  • Figure 6.12 FUJIFILM Diosynth Biotechnologies: Annual Revenues, FY 2017-FY 2021 (JPY Billion)
  • Figure 6.13 FUJIFILM Holdings: Annual Revenues by Business Divisions (JPY Billion)
  • Figure 6.14 KBI Biopharma: Service Portfolio
  • Figure 6.15 Patheon: Service Portfolio
  • Figure 6.16 Patheon: Services and Solutions for Biologics
  • Figure 6.17 Patheon: Annual Revenues, FY 2017-FY 2021 (USD Million)
  • Figure 6.18 Piramal Enterprises: Annual Revenues, FY 2017-FY 2021 (INR Crores)
  • Figure 7.1 Biopharmaceutical Contract Manufacturing in Europe: Growth Drivers and Challenges
  • Figure 7.2 EMA GMP Guidelines: Key Considerations of the Contract Giver, Contract Acceptor and the Contract
  • Figure 7.3 Boehringer Ingelheim: Service Portfolio
  • Figure 7.4 Boehringer Ingelheim: Annual Revenues, FY 2017-FY 2021 (EUR Billion)
  • Figure 7.5 Lonza: Service Portfolio
  • Figure 7.6 Lonza: Annual Revenues, FY 2017-FY 2021 (CHF Billion)
  • Figure 7.7 Lonza: Annual Revenues by Business Divisions (CHF Billion)
  • Figure 7.8 Novasep: Product Portfolio
  • Figure 7.9 Rentschler Biopharma: Service Portfolio
  • Figure 7.10 Sandoz: Annual Revenues, FY 2017-Q1 2022 (USD Billion)
  • Figure 8.1 Chinese Regulatory Guidelines: Key Considerations of the Contract Giver
  • Figure 8.2 Chinese Regulatory Guidelines: Key Considerations of the Contract Acceptor
  • Figure 8.3 Chinese Regulatory Guidelines: Key Aspects of the Contract
  • Figure 8.4 Biopharmaceutical Contract Manufacturing in China: Challenges
  • Figure 8.5 WuXi Biologics: Service Portfolio
  • Figure 8.6 Wuxi Biologics: Annual Revenues, FY 2017-FY 2021 (RMB Million)
  • Figure 8.7 Biopharmaceutical Contract Manufacturing in India: Growth Drivers
  • Figure 8.8 Biopharmaceutical Contract Manufacturing in India: Challenges
  • Figure 8.9 Minaris Regenerative Medicine: Service Portfolio
  • Figure 8.10 Takara Bio: Service Portfolio
  • Figure 8.11 Takara Bio: Annual Revenues, FY 2017-FY 2021 (JPY Million)
  • Figure 8.12 Celltrion: Service Portfolio
  • Figure 8.13 Celltrion: Annual Revenues, FY 2017-Q1 2022 (KRW Billion)
  • Figure 8.14 Samsung BioLogics: Service Portfolio
  • Figure 8.15 Samsung BioLogics: Annual Revenues, FY 2017-Q1 2022 (KRW Billion)
  • Figure 8.16 Cell Therapies: Service Portfolio
  • Figure 8.17 Luina Bio: Service Portfolio
  • Figure 9.1 Structure of a Bispecific Antibody
  • Figure 9.2 Bispecific Antibody Therapeutics Pipeline: Distribution by Phase of Development
  • Figure 9.3 Bispecific Antibody Therapeutics Pipeline: Distribution by Target Indication
  • Figure 9.4 Structure of an Antibody Drug Conjugate (ADC)
  • Figure 9.5 Antibody Drug Conjugates: Distribution by Status of Development
  • Figure 9.6 Antibody Drug Conjugates: Distribution by Target Indication
  • Figure 9.7 Key ADC Technology Providers: Distribution by Number of Candidates
  • Figure 9.8 Decentralized Manufacturing: Process Model
  • Figure 9.9 Cell Therapy Manufacturing: Challenges and Growth Drivers
  • Figure 9.10 Cell Therapy: Potency as Critical Quality Attribute
  • Figure 9.11 Stem Cell Therapies: Distribution by Phase of Development
  • Figure 9.12 T-Cell Therapies: Distribution by Phase of Development
  • Figure 9.13 Gene Therapies: Distribution by Stage of Development
  • Figure 9.14 Gene Therapies: Distribution by Phase of Development
  • Figure 9.15 Clinical and Commercial Pipeline of Gene Therapies: Distribution by Type of Vector Used
  • Figure 9.16 Early-Stage Pipeline of Gene Therapies: Distribution by Type of Vector Used
  • Figure 9.17 Clinical and Commercial Pipeline of Gene Therapies: Distribution by Therapeutic Area
  • Figure 9.18 Early-Stage Pipeline of Gene Therapies: Distribution by Therapeutic Area
  • Figure 9.19 Viral Vector Manufacturers: Distribution by Location of Manufacturing Facility
  • Figure 9.20 Plasmid DNA Manufacturers: Distribution by Location of Manufacturing Facility
  • Figure 10.1 Manufacturing Stages of a Biosimilar Product
  • Figure 10.2 Analytical and Functional Characterization Methods for Key Biosimilar Product
  • Figure 10.3 Regulatory Process Adopted for Licensing of a Biosimilar Product
  • Figure 10.4 Need for Outsourcing Biosimilar Manufacturing Operations
  • Figure 10.5 Biosimilars: Historical Trend of FDA Approval, 2015-2021
  • Figure 10.6 Challenges Associated with Outsourcing Biosimilar Manufacturing Operations
  • Figure 11.1 Small Molecule and Large Molecule Drugs: Historical Trend of FDA Approval, 2005-2021
  • Figure 11.2 Small Molecules versus Large Molecules: Comparison of Manufacturing Process
  • Figure 12.1 Benefits Associated with In-House Manufacturing
  • Figure 12.2 Risks Associated with In-House Manufacturing
  • Figure 12.3 Advantages and Disadvantages of Different Types of Outsourcing Partnerships
  • Figure 13.1 Make versus Buy Decision Making Framework
  • Figure 13.2 Make versus Buy Decision Making: Possible Scenario Descriptions
  • Figure 14.1 Big Pharma Players: Distribution by Number of Biopharmaceutical Contract Manufacturing Focused Initiatives, 1980-2022
  • Figure 14.2 Big Pharma Players: Cumulative Distribution by Year of Initiative
  • Figure 14.3 Big Pharma Players: Distribution by Purpose of Initiative
  • Figure 14.4 Big Pharma Players: Distribution by Type of Initiative
  • Figure 14.5 Big Pharma Players: Distribution by Type of Partnership
  • Figure 14.6 Big Pharma Players: Distribution by Type of Expansion
  • Figure 14.7 Big Pharma Players: Distribution by Scale of Operation
  • Figure 14.8 Big Pharma Players: Distribution by Type of Biologic Manufactured
  • Figure 14.9 Big Pharma Players: Distribution by Year of Initiative and Company (Heat Map Representation)
  • Figure 14.10 Big Pharma Players: Distribution by Purpose of Initiative and Company
  • Figure 14.11 Big Pharma Players: Distribution by Year and Type of Initiative
  • Figure 14.12 Big Pharma Players: Distribution by Region of Expansion and Company
  • Figure 14.13 Big Pharma Players: Distribution by Type of Biologic Manufactured and Company
  • Figure 14.14 Big Pharma Players: Distribution of Top Pharmaceutical Companies (Heat Map Representation)
  • Figure 15.1 Partnerships and Collaborations: Cumulative Year-wise Trend, 2015-2022
  • Figure 15.2 Partnerships and Collaborations: Distribution by Type of Partnership
  • Figure 15.3 Partnerships and Collaborations: Distribution by Year and Type of Partnership
  • Figure 15.4 Partnerships and Collaborations: Distribution by Type of Biologic Manufactured
  • Figure 15.5 Partnerships and Collaborations: Distribution by Year of Partnership and Type of Biologic Manufactured
  • Figure 15.6 Partnerships and Collaborations: Distribution by Type of Partnership and Type of Biologic Manufactured
  • Figure 15.7 Partnerships and Collaborations: Distribution by Type of Biologic Manufactured and Geography
  • Figure 15.8 Partnerships and Collaborations: Distribution by Therapeutic Area
  • Figure 15.9 Most Active Players: Distribution by Number of Partnerships
  • Figure 15.10 Partnerships and Collaborations: Intracontinental and Intercontinental Agreements
  • Figure 15.11 Partnerships and Collaborations: Local and International Agreements
  • Figure 16.1 Mergers and Acquisitions: Year-Wise Cumulative Trend (2015- 2022)
  • Figure 16.2 Mergers and Acquisitions: Distribution by Type of Acquisition
  • Figure 16.3 Mergers and Acquisitions: Distribution by Region (Continent-wise)
  • Figure 16.4 Mergers and Acquisitions: Distribution by Region (Country-wise)
  • Figure 16.5 Mergers and Acquisitions: Year-Wise Trend in North America, Europe and Asia-Pacific (2015- 2022)
  • Figure 16.6 Most Active Acquirers: Distribution by Number of Acquisitions
  • Figure 16.7 Catalent Biologics: Information on Key Acquisitions
  • Figure 16.8 Mergers and Acquisitions: Distribution by Key Value Drivers
  • Figure 16.9 Mergers and Acquisitions: Distribution by Year of Acquisition and Key Value Drivers
  • Figure 16.10 Mergers and Acquisitions: Distribution by Type of Biologic Manufactured
  • Figure 16.11 Mergers and Acquisitions: Distribution by Key Value Drivers and Type of Biologic Manufactured
  • Figure 16.12 Mergers and Acquisitions: Year-Wise Trend of Deal Multiple Amount (USD Million)
  • Figure 17.1 Recent Expansions: Cumulative Year-wise Trend, 2016-2022
  • Figure 17.2 Recent Expansions: Distribution by Purpose of Expansion
  • Figure 17.3 Recent Expansions: Distribution by Year and Purpose of Expansion
  • Figure 17.4 Recent Expansions: Distribution by Type of Biologic Manufactured
  • Figure 17.5 Recent Expansions: Distribution by Purpose of Expansion and Type of Biologic Manufactured
  • Figure 17.6 Recent Expansions: Distribution by Location of Expanded Facility
  • Figure 17.7 Most Active Players: Distribution by Number of Recent Expansions
  • Figure 17.8 Recent Expansions: Distribution by Location of Headquarters and Purpose of Expansion
  • Figure 17.9 Recent Expansions: Distribution by Amount Invested (USD Million)
  • Figure 17.10 Recent Expansions: Regional Comparison 2016-2020 and 2016-2022 Scenario
  • Figure 18.1 Funding and Investment Analysis: Cumulative Year-wise Trend of Number of Funding Instances, 2016-2022
  • Figure 18.2 Funding and Investments: Cumulative Year-wise Trend of Total Amount Invested, 2016-2022 (USD Million)
  • Figure 18.3 Funding and Investment Analysis: Distribution of Number of Instances by Type of Funding
  • Figure 18.4 Funding and Investment Analysis: Distribution of Total Amount Invested by Type of Funding (USD Million)
  • Figure 18.5 Funding and Investment Analysis: Distribution by Year and Type of Funding
  • Figure 18.6 Funding and Investment Analysis: Distribution of Number of Funding Instances and Total Amount Invested by Geography (Continent-wise) (USD Million)
  • Figure 18.7 Funding and Investment Analysis: Distribution of Number of Funding Instances and Total Amount Invested by Geography (Country-wise) (USD Million)
  • Figure 18.8 Most Active Players: Distribution by Number of Funding Instances
  • Figure 18.9 Most Active Players: Distribution by Total Amount Invested (USD Million)
  • Figure 18.10 Most Active Investors: Analysis by Number of Funding Instances
  • Figure 19.1 Capacity Analysis: Distribution by Company Size
  • Figure 19.2 Capacity Analysis: Distribution by Type of Expression System Used
  • Figure 19.3 Capacity Analysis: Distribution by Scale of Operation
  • Figure 19.4 Capacity Analysis: Distribution by Region
  • Figure 19.5 Capacity Analysis: Biopharmaceutical Contract Manufacturing Capacity in North America
  • Figure 19.6 Capacity Analysis: Biopharmaceutical Contract Manufacturing Capacity in Europe
  • Figure 19.7 Capacity Analysis: Biopharmaceutical Contract Manufacturing Capacity in Asia-Pacific
  • Figure 20.1 Global Demand for Biopharmaceuticals, 2022-2035 (in kilograms)
  • Figure 20.2 Demand Analysis: Distribution of Annual Demand by Therapeutic Area
  • Figure 20.3 Demand and Supply Scenario for Biopharmaceuticals, 2022-2035 (Million Liters)
  • Figure 20.4 Demand Analysis: Annual Demand for ADC Therapeutics (in kilograms), 2022-2030
  • Figure 20.5 ADC Therapeutics: Demand and Supply Scenario, 2022-2030
  • Figure 20.6 Global Demand for Cell Therapies, 2022-2030 (in terms of Number of Patients)
  • Figure 20.7 Global Demand for Cell Therapies, 2022-2030 (Billion Cells)
  • Figure 21.1 Total Cost of Ownership: Capital Expenditures (CAPEX)
  • Figure 21.2 Total Cost of Ownership: Operational Expenditures (OPEX)
  • Figure 21.3 Total Cost of Ownership for Mid-sized Biopharmaceutical Contract Manufacturing Organizations, 2022-2042 (USD Million)
  • Figure 21.4 Total Cost of Ownership for Mid-sized Biopharmaceutical Contract Manufacturing Organizations: Distribution by CAPEX and OPEX, 2023 and 2042 (USD Million)
  • Figure 21.5 Total Cost of Ownership for Mid-sized Biopharmaceutical Contract Manufacturing Organizations, 2023: Distribution by CAPEX (USD Million)
  • Figure 21.6 Total Cost of Ownership for Mid-sized Biopharmaceutical Contract Manufacturing Organizations, 2023-2042: Distribution by OPEX (USD Million)
  • Figure 22.1 Global Biopharmaceutical Contract Manufacturing Market, 2022-2035 (USD Billion)
  • Figure 22.2 Biopharmaceutical Contract Manufacturing Market: Distribution by Type of Service(s) Offered
  • Figure 22.3 Biopharmaceutical Contract Manufacturing Market for APIs, 2022-2035 (USD Billion)
  • Figure 22.4 Biopharmaceutical Contract Manufacturing Market for FDFs, 2022-2035 (USD Billion)
  • Figure 22.5 Biopharmaceutical Contract Manufacturing Market: Distribution by Type of Biologic Manufactured
  • Figure 22.6 Biopharmaceutical Contract Manufacturing Market for Antibodies, 2022-2035 (USD Billion)
  • Figure 22.7 Biopharmaceutical Contract Manufacturing Market for Cell Therapies, 2022-2035 (USD Billion)
  • Figure 22.8 Biopharmaceutical Contract Manufacturing Market for Vaccines, 2022-2035 (USD Billion)
  • Figure 22.9 Biopharmaceutical Contract Manufacturing Market for Other Biologics, 2022-2035 (USD Billion)
  • Figure 22.10 Biopharmaceutical Contract Manufacturing Market: Distribution by Type of Expression System Used
  • Figure 22.11 Biopharmaceutical Contract Manufacturing Market for Mammalian Cell-based Operations, 2022-2035 (USD Billion)
  • Figure 22.12 Biopharmaceutical Contract Manufacturing Market for Microbial Cell-based Operations, 2022-2035 (USD Billion)
  • Figure 22.13 Biopharmaceutical Contract Manufacturing Market for Other Expression System-based Operations, 2022-2035 (USD Billion)
  • Figure 22.14 Biopharmaceutical Contract Manufacturing Market: Distribution by Scale of Operation
  • Figure 22.15 Biopharmaceutical Contract Manufacturing Market for Clinical Operations, 2022-2035 (USD Billion)
  • Figure 22.16 Biopharmaceutical Contract Manufacturing Market for Commercial Operations, 2022-2035 (USD Billion)
  • Figure 22.17 Biopharmaceutical Contract Manufacturing Market: Distribution by Company Size
  • Figure 22.18 Biopharmaceutical Contract Manufacturing Market for Small Companies, 2022-2035 (USD Billion)
  • Figure 22.19 Biopharmaceutical Contract Manufacturing Market for Mid-sized Companies, 2022-2035 (USD Billion)
  • Figure 22.20 Biopharmaceutical Contract Manufacturing Market for Large and Very Large Companies, 2022-2035 (USD Billion)
  • Figure 22.21 Biopharmaceutical Contract Manufacturing Market: Distribution by Geography
  • Figure 22.22 Biopharmaceutical Contract Manufacturing Market in North America, 2022-2035 (USD Billion)
  • Figure 22.23 Biopharmaceutical Contract Manufacturing Market in the US, 2022-2035 (USD Billion)
  • Figure 22.24 Biopharmaceutical Contract Manufacturing Market in Canada, 2022-2035 (USD Billion)
  • Figure 22.25 Biopharmaceutical Contract Manufacturing Market in Europe, 2022-2035 (USD Billion)
  • Figure 22.26 Biopharmaceutical Contract Manufacturing Market in Italy, 2022-2035 (USD Billion)
  • Figure 22.27 Biopharmaceutical Contract Manufacturing Market in Germany, 2022-2035 (USD Billion)
  • Figure 22.28 Biopharmaceutical Contract Manufacturing Market in France, 2022-2035 (USD Billion)
  • Figure 22.29 Biopharmaceutical Contract Manufacturing Market in Spain, 2022-2035 (USD Billion)
  • Figure 22.30 Biopharmaceutical Contract Manufacturing Market in the UK, 2022-2035 (USD Billion)
  • Figure 22.31 Biopharmaceutical Contract Manufacturing Market in Rest of Europe, 2022-2035 (USD Billion)
  • Figure 22.32 Biopharmaceutical Contract Manufacturing Market in Asia-Pacific, 2022-2035 (USD Billion)
  • Figure 22.33 Biopharmaceutical Contract Manufacturing Market in China, 2022-2035 (USD Billion)
  • Figure 22.34 Biopharmaceutical Contract Manufacturing Market in India, 2022-2035 (USD Billion)
  • Figure 22.35 Biopharmaceutical Contract Manufacturing Market in South Korea, 2022-2035 (USD Billion)
  • Figure 22.36 Biopharmaceutical Contract Manufacturing Market in Japan, 2022-2035 (USD Billion)
  • Figure 22.37 Biopharmaceutical Contract Manufacturing Market in Rest of Asia-Pacific, 2022-2035 (USD Billion)
  • Figure 22.38 Biopharmaceutical Contract Manufacturing Market in Latin America, 2022-2035 (USD Billion)
  • Figure 22.39 Biopharmaceutical Contract Manufacturing Market in Middle East and North Africa, 2022-2035 (USD Billion)
  • Figure 23.1 Overall Share of Virtual Biopharmaceutical Companies in the Biopharmaceutical Market (USD Billion)
  • Figure 23.2 Overall Share of Virtual Biopharmaceutical Companies in the Biopharmaceutical Contract Manufacturing Market in 2022 (USD Billion)
  • Figure 24.1 Biopharmaceutical Contract Manufacturing: SWOT Analysis
  • Figure 24.2 Global Biopharmaceuticals Market: Distribution of Number of FDA Approvals by Year, 2005-2022
  • Figure 24.3 Comparison of SWOT Factors: Harvey Ball Analysis
  • Figure 26.1 Survey Analysis: Distribution of Respondents by Company Type
  • Figure 26.2 Survey Analysis: Distribution of Respondents by Location of Headquarters
  • Figure 26.3 Survey Analysis: Distribution of Respondents by Designation
  • Figure 26.4 Survey Analysis: Distribution by Biologics Manufacturing Expertise
  • Figure 26.5 Survey Analysis: Distribution by Scale of Manufacturing
  • Figure 26.6 Survey Analysis: Distribution by Location of Production Facilities
  • Figure 26.7 Survey Analysis: Distribution by Type of Expression System Used
  • Figure 26.8 Survey Analysis: Distribution by Type of Bioreactor Used
  • Figure 26.9 Survey Analysis: Distribution by Mode of Operation of Bioreactor
  • Figure 27.1 Concluding Remarks: Overall Market Landscape
  • Figure 27.2 Concluding Remarks: Partnerships and Collaborations
  • Figure 27.3 Concluding Remarks: Mergers and Acquisitions
  • Figure 27.4 Concluding Remarks: Recent Expansions
  • Figure 27.5 Concluding Remarks: Capacity Analysis
  • Figure 27.6 Concluding Remarks: Demand Analysis
  • Figure 27.7 Concluding Remarks: Market Forecast and Opportunity Analysis
  • Figure 27.8 Concluding Remarks: Market Forecast and Opportunity Analysis