3D 细胞培养市场规模、份额、成长分析、按产品、按应用、按最终用户、按地区 - 行业预测，2024-2031 年

2022年3D细胞培养市场规模为13亿美元，从2023年的15.4亿美元成长到2031年的58.5亿美元，预计复合年增长率为18.2%。

3D 系统电子学的进步已经超越了传统技术，是药物研究、临床前测试、组织工程和基础科学的基础。透过让细胞在3D上生长和相互作用，3D 细胞培养物可以与细胞外基质相互作用，使它们比平面 2D 培养物更俱生理相关性。这种多样性包括各种模型，包括球体、类器官、生物列印细胞模型和晶片上器官模型，每种模型都有独特的优点。球体在保持其遗传组成的同时呈现球形形状，由干细胞製成的类器官表现出成熟的功能，晶片上的器官模仿具有动态流体流动的器官结构。在慢性疾病增加和捐赠者短缺的背景下，迫切需要替代医学来替代器官移植，人们对再生医学和组织工程的兴趣日益浓厚，3D细胞培养系统正在开髮用于移植和移植的类器官。分析。此类系统的市场正在经历创新，例如 3D BioFibR 于 2023 年 6 月推出的胶原蛋白纤维产品 CollaFibR 3D Scaffold 和 μCollaFibR，增强了 3D 细胞培养的功能，我们正在见证新产品的推出带来的成长。此外，旨在扩大癌症治疗药物筛检的 3D 体外服务的合作伙伴关係，例如 Charles River Laboratories 和 CELLphenomics 于 2023 年 12 月的合作，将推动市场扩张，这反映了不断增长的需求和协作努力。

目录

介绍

• 这项研究的目的
• 定义
• 市场范围

调查方法

• 资讯采购
• 二手资料来源和主要资料来源
• 市场规模预测
• 市场假设与限制

执行摘要

• 市场概况展望
• 供需趋势分析
• 按细分市场的机会分析

市场动态及展望

• 市场动态
  • 促进因素
  • 机会
  • 抑制因素
  • 任务
• 波特的分析

主要市场考察

• 技术分析
• 价格分析
• 专利分析
• 技术分析
• 客户和购买标准分析
• 市场生态系统
• 监管环境
• 创新矩阵
• 主要投资分析
• 关键成功因素
• 竞争程度

3D 细胞培养市场：依技术分类

• 市场概况
• 基于支架的 3D 细胞培养
  • 水凝胶
  • 天然和合成水凝胶
  • 固体的鹰架
  • 微图案表面
  • 其他的
• 无支架 3D 细胞培养
  • 低附件
  • 悬滴板
  • 3D反应器
  • 3D 培养皿
  • 其他的
• 利用磁性和生物列印进行 3D 细胞培养
• 微流体晶片上的器官模型

3D 细胞培养市场：依应用分类

• 市场概况
• 癌症研究
• 干细胞研究
• 药物发现和毒性测试
• 组织工程与再生医学

3D 细胞培养市场：依最终用途分类

• 市场概况
• 生技/製药公司
• 合约研究实验室
• 化妆品产业
• 学术/研究机构
• 其他的

3D 细胞培养市场：按地区分類的规模

• 市场概况
• 北美洲
  • 美国
  • 加拿大
• 欧洲
  • 德国
  • 西班牙
  • 法国
  • 英国
  • 义大利
  • 其他欧洲国家地区
• 亚太地区
  • 中国
  • 印度
  • 日本
  • 韩国
  • 其他亚太地区
• 拉丁美洲
  • 巴西
  • 其他拉丁美洲地区
• 中东和非洲 (MEA)
  • 海湾合作委员会国家
  • 南非
  • 其他中东/非洲地区

竞争格局

• 前5名企业对比
• 主要企业市场定位（2023年）
• 主要市场参与者所采取的策略
• 近期市集活动
• 主要企业市场占有率（2023年）

主要企业简介

• Thermo Fisher Scientific US
• Merck KGaA
• Corning Incorporated
• Becton, Dickinson And Company
• Lonza
• 3d Biotek LLC
• Advanced Biomatrix, Inc
• Avantor, Inc
• Merck & Co., Inc.
• Tecan Trading AG
• Reprocell Inc
• Emulate
• Synthecon Incorporated
• Insphero AG
• Kirkstall Ltd.
• Promocell GmBh
• UPM Biomedicals
• CN Bio Innovations Ltd
• Synvivo Inc.
• Amsbio

3D Cell Culture Market size was valued at USD 1.3 billion in 2022 and is poised to grow from USD 1.54 billion in 2023 to USD 5.85 billion by 2031, growing at a CAGR of 18.2% during the forecast period (2024-2031).

3D system electronics have become fundamental in drug research, preclinical testing, tissue engineering, and basic sciences, surpassing traditional technologies due to their advancements. By allowing cells to grow and interact in three dimensions, 3D cell cultures enable engagement with the extracellular matrix, enhancing physiological relevance compared to flat 2D cultures. This diversity encompasses various models like spheroids, organoids, bioprinted cell models, and organs-on-chips, each offering unique benefits. Spheroids exhibit spherical shape while maintaining genetic composition, organoids from stem cells exhibit mature function, and organs-on-chips mimic organ structures with dynamic fluid flow. The pressing need for alternatives to organ transplantation, driven by escalating chronic diseases and donor shortages, has spurred interest in regenerative medicine and tissue engineering, where 3D cell culture systems excel in organoid culture and tissue construct development for transplantation and drug response analysis. The market for such systems is witnessing growth with the introduction of innovative products, exemplified by 3D BioFibR's launch of collagen fiber products, CollaFibR 3D scaffold and μCollaFibR, in June 2023, enhancing 3D cell culture capabilities. Additionally, partnerships like that between Charles River Laboratories and CELLphenomics in December 2023, aimed at expanding 3D in vitro services for drug screening in cancer therapy, reflect the increasing demand and collaborative efforts driving market expansion.

Top-down and bottom-up approaches were used to estimate and validate the size of the 3D Cell Culture market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

3D Cell Culture Market Segmental Analysis

3D Cell Culture Market is segmented by Product, Application, End User and region. Based on Product, the market can be segmented into Scaffold-based, Scaffold-free, Bioreactors, and others. Based on Application, the market is segmented into Cancer Research, Stem Cell Research & Tissue Engineering, and Others. Based on End User, the market is segmented into Biotechnology and Pharmaceutical Companies, Academic & Research Institutes, and Others. Based on region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Drivers of the 3D Cell Culture Market

The burgeoning influence of 3D cell culture on advancing regenerative medicine is poised to revolutionize the field, offering a groundbreaking approach that fosters the development of intricate tissue structures mirroring natural environments. This pioneering method enables in-depth exploration of tissue regeneration and engineering, propelling it to the forefront of medical research. As regenerative medicine gains traction as a new paradigm in healthcare, demand for these sophisticated cell culture technologies, such as bio-3D, continues to surge. Consequently, this emerging technology drives growth in the 3D cell culture industry by providing highly specialized tools for researchers and clinicians to comprehend and implement regenerative therapies effectively.

Restraints in the 3D Cell Culture Market

The adoption of 3D cell cultures marks a significant advancement over traditional monolayer cultures, demanding the use of advanced cell culture resources, consequently driving up direct expenses associated with experiments. While offering numerous advantages, the implementation of 3D cell cultures results in higher costs due to the elevated prices of 3D scaffolds and materials compared to those utilized in 2D cell cultures. Especially in drug discovery efforts, where numerous experiments are crucial, employing 3D cell culture methods can inflate drug development expenses substantially, potentially making certain avenues financially unfeasible.

Market Trends of the 3D Cell Culture Market

Cutting-edge advancements in cell culture technologies have led to the rapid evolution of organ-on-a-chip and microfluidic systems, providing increasingly intricate 3D cell culture environments. These innovative platforms empower researchers to mimic inter-organ and tissue interactions with heightened accuracy. For instance, in December 2022, Emulate, Inc., launched the Emulate Chip-A1(TM) Accessible Chip through an early access program. This latest iteration expands upon the capabilities of the original Chip-S1, faithfully reproducing tissue-vascular interfaces with relevant biomechanical stimuli such as stretch and flow. The Chip-A1(TM) allows users to cultivate thicker tissues within the epithelial culture chamber and employ a broader range of drug treatment techniques, including topical or aerosolized applications, thereby augmenting versatility and experimentation capabilities.

Table of Contents

Introduction

• Objectives of the Study
• Definitions
• Market Scope

Research Methodology

• Information Procurement
• Secondary & Primary Data Sources
• Market Size Estimation
• Market Assumptions & Limitations

Executive Summary

• Market Overview Outlook
• Supply Demand Trend Analysis
• Segmental Opportunity Analysis

Market Dynamics & Outlook

• Market Dynamics
  • Drivers
  • Opportunities
  • Restraints
  • Challenges
• Porters Analysis
  • Competitive rivalry
  • Threat of Substitute Products
  • Bargaining Power of Buyers
  • Threat of New Entrants
  • Bargaining Power of Suppliers

Key Market Insights

• Technology Analysis
• Pricing Analysis
• Patent Analysis
• Technology Analysis
• Customer & Buying Criteria Analysis
• Ecosystem of the Market
• Regulatory Landscape
• Innovation Matrix
• Top Investment Analysis
• Key Success Factor
• Degree of Competition

3D Cell Culture Market by Technology

• Market Overview
• Scaffold-based 3D Cell Cultures
  • Hydrogels
  • Natural & Synthetic Hydrogels
  • Solid Scaffolds
  • Micropatterned Surfaces
  • Others
• Scaffold-free 3D Cell Cultures
  • Low Attachment Plates
  • Hanging Drop Plates
  • 3d Bioreactors
  • 3d Petri Dishes
  • Others
• Magnetic & Bioprinted 3d Cell Cultures
• Microfluidic Organ-on-a-Chip Models

3D Cell Culture Market by Application

• Market Overview
• Cancer Research
• Stem Cell Research
• Drug Discovery & Toxicology Testing
• Tissue Engineering & Regenerative Medicine

3D Cell Culture Market by End Use

• Market Overview
• Biotechnology and Pharmaceutical Companies
• Contract Research Laboratories
• Cosmetic Industry
• Academic & Research Institutes
• Others

3D Cell Culture Market Size by Region

• Market Overview
• North America
  • USA
  • Canada
• Europe
  • Germany
  • Spain
  • France
  • UK
  • Italy
  • Rest of Europe
• Asia Pacific
  • China
  • India
  • Japan
  • South Korea
  • Rest of Asia-Pacific
• Latin America
  • Brazil
  • Rest of Latin America
• Middle East & Africa (MEA)
  • GCC Countries
  • South Africa
  • Rest of MEA

Competitive Landscape

• Top 5 Player Comparison
• Market Positioning of Key Players, 2023
• Strategies Adopted by Key Market Players
• Recent Activities in the Market
• Key Companies Market Share (%), 2023

Key Company Profiles

• Thermo Fisher Scientific US
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Merck KGaA
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Corning Incorporated
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Becton, Dickinson And Company
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Lonza
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• 3d Biotek LLC
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Advanced Biomatrix, Inc
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Avantor, Inc
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Merck & Co., Inc.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Tecan Trading AG
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Reprocell Inc
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Emulate
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Synthecon Incorporated
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Insphero AG
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Kirkstall Ltd.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Promocell GmBh
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• UPM Biomedicals
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• CN Bio Innovations Ltd
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Synvivo Inc.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Amsbio
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments