下游加工市场规模、份额和成长分析（按技术、产品、应用、最终用户和地区）- 2025-2032 年产业预测

2023 年下游加工市场规模价值 364 亿美元，预计将从 2024 年的 423.7 亿美元成长到 2032 年的 1,427.8 亿美元，预测期内（2025-2032 年）的复合年增长率为 16.4%。

受生物製药和生物技术产品需求不断增长的推动，全球下游加工市场预计将经历显着增长。随着越来越多的公司寻求生物製药的高效精製和生产技术，下游加工技术变得至关重要。默克与无锡国家高新技术产业开发区达成的合作，体现了该产业对拓展能力的决心。然而，设备成本高、初始投资大等挑战可能会阻碍企业成长，尤其是对中小型企业而言。层析法和过滤的进步正在提高效率和扩充性，而向一次性技术的转变则简化了流程、最大限度地降低了污染风险并加快了生产时间。随着生物製药产业的持续成长，颠覆性的市场格局预计将推动对创新解决方案的需求激增。

目录

介绍

• 调查目的
• 研究范围
• 定义

调查方法

• 资讯采购
• 次要和主要资料方法
• 市场规模预测
• 市场假设与限制

执行摘要

• 全球市场展望
• 供需趋势分析
• 细分机会分析

市场动态及展望

• 市场概况
• 市场规模
• 市场动态
  • 驱动因素和机会
  • 限制与挑战
• 波特的分析

主要市场考察

• 关键成功因素
• 竞争程度
• 主要投资机会
• 市场生态系统
• 市场吸引力指数（2024 年）
• PESTEL 分析
• 总体经济指标
• 价值链分析
• 定价分析

下游加工市场规模（依技术及复合年增长率） (2025-2032)

• 市场概况
• 精製
• 固液分离
• 澄清/浓缩

下游加工市场规模（按产品和复合年增长率） (2025-2032)

• 市场概况
• 层析管柱和树脂
• 筛选器
• 膜吸附装置
• 免洗用品
• 其他产品
  • 耗材和
  • 配件

下游加工市场规模（按应用和复合年增长率） (2025-2032)

• 市场概况
• 单株抗体生产
• 疫苗生产
• 胰岛素生成
• 免疫球蛋白的产生
• 促红血球生成素的产生
• 其他用途
  • 干扰素
  • 融合蛋白
  • 生长激素
  • 凝血因子
  • 抗凝血剂
  • 医用酶
  • 抗菌
  • 抗生素
  • 集落刺激因子

下游加工市场规模（按最终用户和复合年增长率） (2025-2032)

• 市场概况
• 生物製药製造商
• 契约製造组织（CMO）

下游加工市场规模（按地区）及复合年增长率（2025-2032）

• 北美洲
  • 美国
  • 加拿大
• 欧洲
  • 德国
  • 西班牙
  • 法国
  • 英国
  • 义大利
  • 其他欧洲国家地区
• 亚太地区
  • 中国
  • 印度
  • 日本
  • 韩国
  • 其他亚太地区
• 拉丁美洲
  • 巴西
  • 其他拉丁美洲国家
• 中东和非洲
  • 海湾合作委员会国家
  • 南非
  • 其他中东和非洲地区

竞争资讯

• 前 5 家公司对比
• 主要企业市场定位（2024年）
• 主要市场参与者所采用的策略
• 近期市场趋势
• 公司市场占有率分析（2024 年）
• 主要企业简介
  • 公司详细信息
  • 产品系列分析
  • 公司分部份额分析
  • 收益与前一年同期比较对比（2022-2024 年）

主要企业简介

• Thermo Fisher Scientific Inc.（US）
• Merck KGaA（MilliporeSigma）（Germany）
• Danaher Corporation（Cytiva）（US）
• Sartorius Stedim Biotech SA（France）
• Lonza Group AG（Switzerland）
• 3M Company（US）
• Boehringer Ingelheim International GmbH（Germany）
• Eppendorf AG（Germany）
• Repligen Corporation（US）
• GE Healthcare（US）
• Corning Incorporated（US）
• Dover Corporation（US）
• Asahi Kasei（Japan）
• Pall Corporation（US）
• Bio-Rad Laboratories, Inc.（US）
• Agilent Technologies Inc.（US）
• Finesse Solutions, Inc.（US）
• Novasep（France）
• Rentschler Biopharma（Germany）
• Vetter Pharma International GmbH（Germany）

结论和建议

Downstream Processing Market size was valued at USD 36.4 billion in 2023 and is poised to grow from USD 42.37 billion in 2024 to USD 142.78 billion by 2032, growing at a CAGR of 16.4% during the forecast period (2025-2032).

The Global Downstream Processing Market is set for significant growth driven by the rising demand for biopharmaceuticals and biotechnology products. As companies increasingly seek efficient purification and production techniques for biotherapeutics, downstream processing technologies become essential. Collaborations like Merck's agreement with Wuxi National High-tech Industrial Development Zone illustrate the industry's commitment to expanding capabilities. However, challenges such as high equipment costs and substantial initial investments may hinder growth, particularly for smaller firms. Advancements in chromatography and filtration are improving efficiency and scalability, while the shift toward single-use technologies is streamlining processes, minimizing contamination risks, and accelerating production timelines. As the biopharmaceutical sector continues to thrive, the demand for innovative downstream processing solutions will likely surge, promising a dynamic market landscape.

Top-down and bottom-up approaches were used to estimate and validate the size of the Downstream Processing market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

Downstream Processing Market Segments Analysis

Global Downstream Processing Market is segmented by Technique, Product, Application, End User and region. Based on Technique, the market is segmented into Purification, Solid-liquid Separation and Clarification/Concentration. Based on Product, the market is segmented intoChromatographyColumns and Resins, Filters, Membrane Adsorbers, Single-use Products and Other Products. Based on Application, the market is segmented into Monoclonal Antibody Production, Vaccine Production, Insulin Production, Immunoglobulin Production, Erythropoietin Production and Other Applications. Based on End User, the market is segmented into Biopharmaceutical Manufacturers and Contract Manufacturing Organizations (CMOs). Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.

Driver of the Downstream Processing Market

The increasing need for biopharmaceuticals, including monoclonal antibodies, vaccines, and recombinant proteins, is driving growth in the downstream processing market. This sector is essential for the purification and isolation of these intricate biological products, which is vital for ensuring their safety and effectiveness. As the biopharmaceutical industry continues to expand, there is a corresponding surge in the demand for advanced downstream processing technologies and equipment. This trend highlights the critical role that downstream processing plays in the overall biopharmaceutical production pipeline, thereby making it a key driver for market development and innovation in the industry.

Restraints in the Downstream Processing Market

The Downstream Processing market faces various restraints due to the unique attributes of each biopharmaceutical product, including size, charge, solubility, and stability. These distinct characteristics can lead to complications such as low yields, challenging purification processes, and a heightened risk of degradation throughout purification stages. As a result, creating customized downstream processes for diverse products, while simultaneously tackling product-specific obstacles, can be quite intricate. This complexity necessitates a high level of expertise and considerable optimization efforts, ultimately making it a significant challenge for companies operating within this field to achieve efficient and effective processing solutions.

Market Trends of the Downstream Processing Market

The downstream processing market is witnessing a significant trend towards process intensification and continuous manufacturing methodologies, driven by the need for enhanced efficiency and productivity in biopharmaceutical production. Techniques such as continuous chromatography and continuous centrifugation are becoming increasingly popular, offering benefits like real-time monitoring and improved process control. These innovations facilitate the optimization of processing operations, resulting in higher yields and reduced processing times. As companies strive to shorten production timelines and minimize costs, the adoption of these advanced technologies is poised to reshape the downstream processing landscape, underscoring the industry's commitment to continuous improvement and operational excellence.

Table of Contents

Introduction

• Objectives of the Study
• Scope of the Report
• Definitions

Research Methodology

• Information Procurement
• Secondary & Primary Data Methods
• Market Size Estimation
• Market Assumptions & Limitations

Executive Summary

• Global Market Outlook
• Supply & Demand Trend Analysis
• Segmental Opportunity Analysis

Market Dynamics & Outlook

• Market Overview
• Market Size
• Market Dynamics
  • Drivers & Opportunities
  • Restraints & Challenges
• Porters Analysis
  • Competitive rivalry
  • Threat of substitute
  • Bargaining power of buyers
  • Threat of new entrants
  • Bargaining power of suppliers

Key Market Insights

• Key Success Factors
• Degree of Competition
• Top Investment Pockets
• Market Ecosystem
• Market Attractiveness Index, 2024
• PESTEL Analysis
• Macro-Economic Indicators
• Value Chain Analysis
• Pricing Analysis

Global Downstream Processing Market Size by Technique & CAGR (2025-2032)

• Market Overview
• Purification
• Solid-liquid Separation
• Clarification/Concentration

Global Downstream Processing Market Size by Product & CAGR (2025-2032)

• Market Overview
• Chromatography Columns and Resins
• Filters
• Membrane Adsorbers
• Single-use Products
• Other Products
  • Consumables an
  • Accessories

Global Downstream Processing Market Size by Application & CAGR (2025-2032)

• Market Overview
• Monoclonal Antibody Production
• Vaccine Production
• Insulin Production
• Immunoglobulin Production
• Erythropoietin Production
• Other Applications
  • Interferons
  • Fusion Proteins
  • Growth Hormones
  • Blood Coagulation Factors
  • Anticoagulants
  • Medical Enzymes
  • Anti-bacterial
  • Antibiotics
  • Colony Stimulating Factors

Global Downstream Processing Market Size by End User & CAGR (2025-2032)

• Market Overview
• Biopharmaceutical Manufacturers
• Contract Manufacturing Organizations (CMOs)

Global Downstream Processing Market Size & CAGR (2025-2032)

• North America (Technique, Product, Application, End User)
  • US
  • Canada
• Europe (Technique, Product, Application, End User)
  • Germany
  • Spain
  • France
  • UK
  • Italy
  • Rest of Europe
• Asia Pacific (Technique, Product, Application, End User)
  • China
  • India
  • Japan
  • South Korea
  • Rest of Asia-Pacific
• Latin America (Technique, Product, Application, End User)
  • Brazil
  • Rest of Latin America
• Middle East & Africa (Technique, Product, Application, End User)
  • GCC Countries
  • South Africa
  • Rest of Middle East & Africa

Competitive Intelligence

• Top 5 Player Comparison
• Market Positioning of Key Players, 2024
• Strategies Adopted by Key Market Players
• Recent Developments in the Market
• Company Market Share Analysis, 2024
• Company Profiles of All Key Players
  • Company Details
  • Product Portfolio Analysis
  • Company's Segmental Share Analysis
  • Revenue Y-O-Y Comparison (2022-2024)

Key Company Profiles

• Thermo Fisher Scientific Inc. (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Merck KGaA (MilliporeSigma) (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Danaher Corporation (Cytiva) (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Sartorius Stedim Biotech S.A. (France)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Lonza Group AG (Switzerland)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• 3M Company (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Boehringer Ingelheim International GmbH (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Eppendorf AG (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Repligen Corporation (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• GE Healthcare (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Corning Incorporated (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Dover Corporation (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Asahi Kasei (Japan)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Pall Corporation (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Bio-Rad Laboratories, Inc. (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Agilent Technologies Inc. (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Finesse Solutions, Inc. (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Novasep (France)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Rentschler Biopharma (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Vetter Pharma International GmbH (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments

Conclusion & Recommendations