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基因治疗学和RNAi

蛋白质表现市场规模、份额及成长分析（按产品/服务、系统类型、应用、最终用户和地区划分）－2026-2033年产业预测

市场调查报告书

商品编码

1903154

蛋白质表现市场规模、份额及成长分析（按产品/服务、系统类型、应用、最终用户和地区划分）－2026-2033年产业预测

Protein Expression Market Size, Share, and Growth Analysis, By Product and Service (Reagents, Expression Vectors), By System Type, By Application, By End User, By Region - Industry Forecast 2026-2033

出版日期: 2025年12月24日 | 出版商:

SkyQuest | 英文 209 Pages | 商品交期: 3-5个工作天内

价格

简介目录

预计到 2024 年，蛋白质表现市场规模将达到 37.3 亿美元，到 2025 年将成长至 42.2 亿美元，到 2033 年将成长至 114.7 亿美元，在预测期（2026-2033 年）内，预计复合年增长率为 13.3%。

受治疗应用领域对重组蛋白需求不断增长的推动，蛋白质表现市场正经历显着成长。生物技术的进步提高了效率和蛋白质产量，而个人化医疗的趋势则催生了对客製化蛋白质疗法的需求。在个人化医疗的广泛应用和蛋白质工程创新的推动下，持续的研发投入正在推动市场扩张。重组蛋白的人工合成为透过客製化医疗解决方案改善患者照护创造了机会。市场参与企业正与学术机构建立策略伙伴关係，共同开发尖端技术以支持个人化治疗。此外，对桿状病毒系统以及昆虫和哺乳动物细胞表现技术等各种蛋白质表现技术的投资不断增加，也进一步推动了市场成长。

全球蛋白质表现市场按产品/服务、系统类型、应用、最终用户和地区进行细分。依产品/服务划分，可分为试剂、表现载体、胜任细胞细胞、设备及服务。依系统类型划分，可分为哺乳动物细胞表现系统、原核生物表现系统、昆虫细胞表现系统、酵母表现系统、无细胞表现系统和藻类表现系统。依应用划分，可分为治疗应用、科研应用及工业应用。按最终用户划分，可分为製药和生物技术公司、学术研究机构、受託研究机构和合约开发与生产组织（CRO 和 CDMO）以及其他最终用户。按地区划分，可分为北美、欧洲、亚太、中东和非洲以及拉丁美洲。

蛋白质表现市场驱动因素

由于大肠桿菌这种广泛应用的表达宿主能够进行大规模蛋白质生产，蛋白质表现市场经历了显着增长。大肠桿菌的优势在于其基因组特征明确且定序能力强，从而能够实现高效的克隆过程。这使其成为製药业蛋白质生产的首选。此外，该系统的使用还能提高启动子区域的结合强度并优化转录效率。这些因素共同推动了蛋白质表现市场需求的成长，也反映了大肠桿菌在生物製药领域的重要角色。

蛋白质表现市场限制因素

蛋白质表现市场面临巨大的进入门槛，主要原因是蛋白质表现试剂高成本。此外，人们对相关疾病整体缺乏了解，也导致许多公司犹豫不决，不敢进入这一领域。对于预算较为紧张的中小型企业和开发中国家的公司而言，这种情况尤其严峻。此外，缺乏完善的保险体係也限制了真核表达系统产品的普及，使得新兴经济体难以充分利用这个市场的潜力。

蛋白质表现市场趋势

微流体技术的出现代表了蛋白质表现市场的一大趋势，这得益于其在微米尺度上以无与伦比的精度操控流体的独特能力。这种创新方法能够精确控制极少量流体，进而增强蛋白质表现过程，使其成为优化蛋白质合成条件的理想选择。微流体装置能够建构复杂的通道和腔室，从而支援高效的蛋白质表现环境。这使得研究人员能够快速筛检各种实验条件，最终简化工作流程，提高蛋白质研发效率，加速生物技术和医学的进步。

哺乳动物细胞表现系统
- 中国仓鼠卵巢细胞株（CHO细胞株）
- 人类胚胎肾细胞株（Hek 293细胞株）
- 其他哺乳动物细胞株
原核表达系统
- 大肠桿菌系统
- 其他原核表达系统
昆虫细胞表现系统
- 桿状病毒系统
- 其他昆虫细胞株
酵母表现系统
- 毕赤酵母系统
- 酿酒酵母系统
- 其他酵母表现系统
无细胞表现系统
基于藻类的表达系统

按应用分類的蛋白质表现市场

治疗用途
研究用途
工业应用

按最终用户分類的蛋白质表现市场

製药和生物技术公司
学术研究机构
CRO（受託研究机构）和 CDMO（合约开发和生产组织）
其他最终用户

蛋白质表现市场：按地区分類的市场规模：

北美洲
- 美国
- 加拿大
欧洲
- 德国
- 西班牙
- 法国
- 英国
- 义大利
- 其他欧洲地区
亚太地区
- 中国
- 印度
- 日本
- 韩国
- 亚太其他地区
拉丁美洲
- 巴西
- 其他拉丁美洲地区
中东和非洲（MEA）
- 海湾合作委员会国家
- 南非
- 其他中东和非洲地区

竞争格局

前五大公司对比
主要企业的市场定位（2025 年）
主要市场参与者所采取的策略
近期市集活动
主要企业市占率（2025 年）

主要企业简介

Thermo Fisher Scientific, Inc.（US）
Merck KGaA（Germany）
Genscript Biotech Corporation（China）
Agilent Technologies Inc.（US）
Takara Bio, Inc.（Japan）
Bio-Rad Laboratories, Inc.（US）
Qiagen NV（Netherlands）
Charles River Laboratories International, Inc.（US）
Danaher Corporation（US）
Sartorius AG（Germany）
Corning Incorporated（US）
Fujifilm Irvine Scientific, Inc.（Acquired by Fujifilm Holdings Corporation）（US）
Lonza Group AG（Switzerland）
Bioneer Corporation（South Korea）
Promega Corporation（US）
Oxford Expression Technologies Ltd.（UK）
Proteogenix（France）
Abeomics Inc.（US）
New England Biolabs, Inc.（US）
Promab Biotechnologies（US）
Sino Biological, Inc.（China）
Jena Bioscience（Germany）
Lifesensors, Inc.（US）
Leading Biology, Inc.（US）
Peak Proteins（UK）

简介目录

Product Code: SQMIG35H2291

Protein Expression Market size was valued at USD 3.73 Billion in 2024 and is poised to grow from USD 4.22 Billion in 2025 to USD 11.47 Billion by 2033, growing at a CAGR of 13.3% during the forecast period (2026-2033).

The protein expression market is witnessing significant growth, driven by the rising need for recombinant proteins in therapeutic applications. Advances in biotechnology are enhancing efficiency and protein yield, while the trend toward personalized medicine is creating demand for tailored protein therapies. Continued investment in research and development is fueling this market expansion, spurred by the popularity of personalized therapeutics and innovations in protein engineering. With the artificial synthesis of recombinant proteins, opportunities to improve patient care through customized medical solutions are emerging. Market participants are forming strategic partnerships with academic institutions to develop cutting-edge technologies that support personalized treatments. Additionally, funding is directed toward various protein expression technologies, including baculovirus systems and expression in insect and mammalian cells, further propelling market growth.

Top-down and bottom-up approaches were used to estimate and validate the size of the Protein Expression market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

Protein Expression Market Segments Analysis

Global Protein Expression Market is segmented on the product & service, system type, application, end user, and region. By product and service, the market is segmented into Reagents, Expression Vectors, Competent Cells, Instruments, and Services. By system type, the market is segmented into Mammalian Cell Expression Systems, Prokaryotic Expression Systems, Insect Cell Expression Systems, Yeast Expression Systems, Cell-Free Expression Systems, and Algal-Based Expression Systems. By application, the market is segmented into Therapeutic Applications, Research Applications, and Industrial Applications. By end user, the market is segmented into Pharmaceutical & Biotechnology Companies, Academic Research Institutes, Contract Research Organizations & Contract Development and Manufacturing Organizations (CROs & CDMOs), and Other End Users. By region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Driver of the Protein Expression Market

The protein expression market is experiencing significant growth due to the large-scale production of proteins using E. coli bacteria, which serves as a widely adopted artificial expression host. The advantages of E. coli lie in its well-characterized genomic and sequencing capabilities, facilitating streamlined cloning processes. This makes E. coli the preferred choice within the pharmaceutical industry for protein production. Furthermore, the utilization of this system enhances the binding strength in the promoter region, thereby optimizing transcription efficiency. These factors collectively contribute to the increasing demand and expansion of the protein expression market, reflecting the pivotal role of E. coli in biopharmaceuticals.

Restraints in the Protein Expression Market

The Protein Expression market faces significant barriers that hinder the entry of new organizations, primarily due to the high costs associated with protein expression reagents. Additionally, a general lack of awareness regarding related diseases contributes to the reluctance of numerous companies to participate in this sector. This situation is particularly challenging for small enterprises and those in developing nations, where budget constraints are more pronounced. Moreover, the absence of favorable insurance frameworks further limits the adoption of eukaryotic expression system products, making it difficult for emerging economies to tap into the potential of this market.

Market Trends of the Protein Expression Market

The advent of microfluidics technology is shaping a significant trend in the Protein Expression market, driven by its ability to manipulate fluids at a microscale with unparalleled precision. This innovative approach enhances the protein expression process by enabling accurate control over minimal fluid volumes, which is ideal for optimizing conditions for protein synthesis. Microfluidic devices facilitate the creation of intricate channels and chambers that support efficient protein expression environments. As a result, researchers can conduct rapid screenings across diverse experimental conditions, ultimately streamlining workflows and improving productivity in protein research and development, thus accelerating advancements in biotechnology and pharmaceuticals.

Introduction

Objectives of the Study
Definitions
Market Scope

Research Methodology

Information Procurement
Secondary & Primary Data Sources
Market Size Estimation
Market Assumptions & Limitations

Executive Summary

Market Overview Outlook
Supply Demand Trend Analysis
Segmental Opportunity Analysis

Market Dynamics & Outlook

Market Dynamics
- Drivers
- Opportunities
- Restraints
- Challenges
Porters Analysis
- Competitive rivalry
- Threat of Substitute Products
- Bargaining Power of Buyers
- Threat of New Entrants
- Bargaining Power of Suppliers

Key Market Insights

Key Success Factor
Degree of Competition
Top Investment Pockets
Ecosystem of the Market
Pricing Analysis
Technology Analysis
Patent Analysis
Value Chain Analysis
Supply Chain Analysis
Customer & Buying Criteria Analysis
Regulatory Analysis

Protein Expression Market, By Product & Service

Market Overview
Reagents
Expression Vectors
Competent Cells
Instruments
Services

Protein Expression Market, By System Type

Market Overview
Mammalian Cell Expression Systems
- Chinese Hamster Ovary Cell Systems (Cho Cell Systems)
- Human Embryonic Kidney Cell Systems (Hek 293 Cell Systems)
- Other Mammalian Cell Systems
Prokaryotic Expression Systems
- Escherichia Coli Systems
- Other Prokaryotic Expression Systems
Insect Cell Expression Systems
- Baculovirus Systems
- Other Insect Cell Systems
Yeast Expression Systems
- Pichia Systems
- Saccharomyces Systems
- Other Yeast Expression Systems
Cell-Free Expression Systems
Algal-Based Expression Systems

Protein Expression Market, By Application

Market Overview
Therapeutic Applications
Research Applications
Industrial Applications

Protein Expression Market, By End User

Market Overview
Pharmaceutical & Biotechnology Companies
Academic Research Institutes
Contract Research Organizations & Contract Development & Manufacturing Organizations (CROS & CDMOs)
Other End Users

Protein Expression Market Market Size by Region

Market Overview
North America
- USA
- Canada
Europe
- Germany
- Spain
- France
- UK
- Italy
- Rest of Europe
Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of Asia-Pacific
Latin America
- Brazil
- Rest of Latin America
Middle East & Africa (MEA)
- GCC Countries
- South Africa
- Rest of MEA

Competitive Landscape

Top 5 Player Comparison
Market Positioning of Key Players, 2025
Strategies Adopted by Key Market Players
Recent Activities in the Market
Key Companies Market Share (%), 2025

Key Company Profiles

Thermo Fisher Scientific, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Merck KGaA (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Genscript Biotech Corporation (China)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Agilent Technologies Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Takara Bio, Inc. (Japan)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Bio-Rad Laboratories, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Qiagen N.V. (Netherlands)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Charles River Laboratories International, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Danaher Corporation (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Sartorius AG (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Corning Incorporated (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Fujifilm Irvine Scientific, Inc. (Acquired by Fujifilm Holdings Corporation) (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Lonza Group AG (Switzerland)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Bioneer Corporation (South Korea)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Promega Corporation (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Oxford Expression Technologies Ltd. (UK)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Proteogenix (France)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Abeomics Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
New England Biolabs, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Promab Biotechnologies (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Sino Biological, Inc. (China)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Jena Bioscience (Germany)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Lifesensors, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Leading Biology, Inc. (US)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments
Peak Proteins (UK)
- Company Overview
- Business Segment Overview
- Financial Updates
- Key Developments