市场调查报告书
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1284285
到 2028 年蛋白质纯化和分离市场预测 - 按产品、技术、应用、最终用户和地区分列的全球分析Protein Purification and Isolation Market Forecasts to 2028 - Global Analysis By Product, Technology, Application, End User and By Geography |
根据Stratistics MRC,2022年全球蛋白质纯化分离市场规模将达到82.4亿美元,预计2028年将达到174亿美元,预计复合年增长率为13.26% 2020年。
蛋白质纯化是利用物理差异从细胞、组织和生物体的复杂混合物中去除蛋白质的过程。 蛋白质纯化需要获得大量纯净的功能性蛋白质。 为了获得所需的蛋白质,该过程将蛋白质与混合物中的非蛋白质成分分离。 它们主要用于对蛋白质结构、功能和相互作用进行分类。 亲和层析、免疫沉淀、蛋白质组学、□分析等是一些常用的蛋白质纯化和分离技术。
根据Research America 2022年1月发布的一份报告,2020年生物製药企业将投入约1222.04亿美元,而2019年将投入约1109.32亿美元用于研发。 因此,这些事实有望推动该国的市场增长。
市场扩张的主要驱动力之一是发现新型配体(例如基于蛋白质的治疗化合物)的重要性与日俱增。 全球蛋白质纯化和分离市场受到对用于快速筛选、製备、纯化和富集蛋白质样品的快速纯化试剂盒不断增长的需求的推动。 此外,由于各种因素,例如公共和私人研究机构增加研发资金以及扩大对基于结构的药物设计的研究,市场有望扩大。
蛋白质纯化和分离技术通常需要特殊的工具、试剂和人力资源,导致总体成本高昂。 对于资源有限的研究人员和机构来说,获得此类技术的机会可能会受到限制。 此外,蛋白质纯化和分离非常耗时,需要许多步骤,例如细胞裂解、层析和过滤。 蛋白质纯化可能耗时、低效且不可扩展。
政府增加研发投资以及鼓励研发增长和扩张的计划将使製药和生物技术行业受益。 额外的好处包括补贴、法规和税收优惠。 对生物标誌物特异性分子研发的大量投资使製药行业成为蛋白质纯化和分离产品的高利润市场。
蛋白质纯化和分离过程可能需要遵守监管要求和质量标准,尤其是在生物技术和製药应用中。 为满足这些要求,整个过程可能会变得更加复杂和昂贵。 此外,还没有能够成功分离和纯化所有类型蛋白质的纯化技术。 不同的蛋白质可能需要以特定的方式进行纯化以适应它们的特性,从而使过程更加复杂和多变。
蛋白质纯化和分离市场受到 COVID-19 供应链中断和交付製造用于蛋白质纯化和分离的试剂盒、试剂和消耗品所需的关键材料的延迟的负面影响。 由于卡车运输瓶颈和港口检查、许多国家的出口禁令、运营中的製造设施减少以及运输和製造货物的医疗保健,大流行导致关键货物的交付延误。这给市场带来了重大挑战,例如工人短缺。 结果,这种情况最初阻碍了市场的增长。 然而,近年来随着蛋白质纯化和分离技术被用于分析和研究新出现的急性呼吸系统综合症冠状病毒 (SARS-CoV-2),需求有所增加。
在预测期内,耗材部分预计将在蛋白质纯化和分离领域占据最大的市场份额。 该细分市场的巨大市场份额主要是由于耗材在蛋白质纯化中的频繁使用以及学术和医学研究机构以及製药公司等各种最终用户对生物製药开发的兴趣日益浓厚。。
预计超滤部分在预测期内将呈现最高增长率。 超滤是一种用于去除液体中溶解的分子和非常小的颗粒的技术。 分子大小是分离的主要依据,但样品的化学、分子和静电特性也会影响过滤器的渗透性。 蛋白质和缓衝液组分通常使用超滤分离,用于缓衝液交换、浓缩和脱盐。 超滤的优势及其在蛋白质纯化和分离中的广泛应用是预测期内推动该细分市场增长的主要因素。
由于蛋白质纯化市场的众多参与者、研发基础设施的发展以及蛋白质组学技术的发展,在预测期内,北美将继续主导全球蛋白质纯化市场。 北美市场对技术先进的蛋白质分离技术的需求也受到蛋白质-蛋白质相互作用研究、目标识别、药物筛选、蛋白质治疗、生物标誌物发现、疾病监测和诊断测试等应用领域改进的推动。
在预测期内,亚太地区预计增长良好。 该地区对蛋白质纯化和分离解决方案的需求预计将受到政府在中国和印度等发展中国家建设医疗保健基础设施的努力的推动。 此外,这些政府正在资助尖端纯化和分离技术的开发。 此外,促进国内药品生产和生物仿製药大规模生产的努力也有助于扩大市场。
2022 年 6 月,默克和马利肯理论化学中心合作开展了一个机器学习项目。 这项为期三年的合作将侧重于开髮用于计算化学建模的新工具和新分子表示。
2022 年 4 月,Thermo Fisher Scientific 与 Matrix Clinical Trials 合作加强了其临床研究解决方案。 服务科学的全球领导者 Thermo Fisher Scientific 旗下的 PPD 临床研究业务与 Matrix Medical Network 提供的 Matrix Clinical Trials 将合作开展临床试验,以创新的分散式临床试验(DCT)解决方案提供给患者。
According to Stratistics MRC, the Global Protein Purification and Isolation Market is accounted for $8.24 billion in 2022 and is expected to reach $17.40 billion by 2028 growing at a CAGR of 13.26% during the forecast period. Protein purification is the process of removing proteins using physical differences from complex mixtures of cells, tissues, or organisms. Large amounts of functional protein with few impurities are sought after by the protein purification procedure. In order to obtain the desired protein, the process separates proteins from non-protein components in a mixture. They are primarily used to categorize the protein's structure, function, and interactions. Affinity chromatography, immunoprecipitation, proteomics, or enzyme assays are a few of the frequently employed techniques for protein purification and isolation.
According to the report published by the Research America in January 2022, the biopharmaceutical companies invested around USD 122,204 million in 2020, wheras in 2019 the investment was around USD 110,932 million in R&D. Therefore, such fact is anticipated to drive the growth of the market in the country.
One of the main factors fueling market expansion is the growing importance of discovering novel ligands, such as protein-based therapeutic compounds. The global protein purification and isolation market is being driven by the increasing demand for rapid purification kits to quickly screen, prepare, purify, and concentrate protein samples. The market is also expected to grow as a result of a number of factors, including increased funding from both public and private research organizations for R&D and expanding research in structure-based drug design.
Techniques for protein purification and isolation frequently require specialized tools, reagents, and personnel, which raises the overall cost. For researchers and institutions with limited resources, this may limit their access to these techniques. Additionally, the process of purifying and isolating proteins can be time-consuming and involve numerous steps, including cell lysis, chromatography, and filtration. Protein purification may be less effective and less scalable as a result of the drawn-out processes.
Increased government investments in R&D and programs fostering their growth and expansion benefit the pharmaceutical and biotechnology industries. Additionally, they offer benefits in the form of grants, regulations, and tax breaks. Due to the significant investments made in studying and creating molecules specific to biomarkers, the pharmaceutical industry is a very lucrative market for goods involving protein purification and isolation.
Regulatory requirements and quality standards may apply to the protein purification and isolation process, particularly when it is used in biotechnology or pharmaceutical applications. The process as a whole may become more complicated and expensive due to compliance with these requirements. Additionally, there isn't a purification technique that can successfully isolate and purify every kind of protein. The process becomes more complex and variable as a result of the potential need for different proteins to be purified using specific methods tailored to their individual characteristics.
The protein purification and isolation market was negatively impacted by the supply chain disruption caused by COVID-19 and the delay in the delivery of crucial goods needed for the production of the kits, reagents, and consumables used in protein purification and isolation. A pandemic presents the market with a number of significant challenges, such as trucking bottlenecks and port checkpoints that slow down deliveries of essential supplies, export bans imposed in many nations, a dearth of operational manufacturing facilities, and a shortage of healthcare workers to transport and produce goods. As a result, this situation initially prevented market growth. The use of protein purification and isolation techniques for analysis and research involving the ever-emerging acute respiratory syndrome coronavirus (SARS-CoV-2) has, however, led to an increase in demand in recent years.
During the forecast period, the consumables segment is anticipated to hold the largest market share for protein purification and isolation. The significant market share of this sector is primarily attributable to the frequent use of consumables for protein purification and the attention paid to the development of biopharmaceuticals by a variety of end users, including academic and medical research institutions and pharmaceutical firms.
Over the forecast period, the ultrafiltration segment is anticipated to grow at the highest rate. Ultrafiltration is a technique used to remove dissolved molecules and incredibly small particles from liquids. The size of the molecules serves as the main basis for separation, though the sample's chemical, molecular, or electrostatic properties may also have an impact on the filter's permeability. Proteins and buffer components are typically separated using ultrafiltration for buffer exchange, concentration, or desalination. Ultrafiltration's benefits and widespread use in protein purification and isolation are the primary factors driving the segment's growth over the forecast period.
The presence of numerous protein purification market players, a developed research and development infrastructure, and technological developments in the proteomics sector all contribute to North America's continued dominance of the global protein purification market over the forecast period. The demand for technologically advanced protein isolation technologies in the North American market is also being driven by improved application fields like protein-protein interaction studies, target identification, drug screening, protein therapeutics, biomarker discovery, disease monitoring, and diagnostic tests.
Over the forecast period, Asia-Pacific is anticipated to experience lucrative growth. The demand for protein purification and isolation solutions in this region is expected to be driven by government initiatives for the development of healthcare infrastructure in developing nations like China and India. Moreover, these governments are funding the creation of cutting-edge purification and isolation techniques. Additionally, initiatives promoting domestic pharmaceutical production and the high volume of biosimilar production contribute to the market's expansion.
Some of the key players profiled in the Protein Purification and Isolation Market include Abcam plc, Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Danaher, G.E. Healthcare Life Sciences, Kamada Ltd., Lanleys International Inc., Leaf Expression Systems, Major Science, Merck KGaA, MNPHARM, Mtibio, Noble Life Sciences, Inc., Norgen Biotek Corporation, Promega Corporation, Qiagen N.V., Sigma-Aldrich Corporation, Takara Bio Inc and Thermo Fischer Scientific, Inc.
In June 2022, Merck and Mulliken Center for Theoretical Chemistry Collaborated in Machine Learning Project. The three-year collaboration will focus on developing new tools for computational chemistry modeling and new molecular representations.
In April 2022, Thermo Fisher Scientific Enhanced Clinical Research Solutions in Collaboration with Matrix Clinical Trials. The PPD clinical research business of Thermo Fisher Scientific Inc., the world leader in serving science, and Matrix Clinical Trials, a Matrix Medical Network offering, collaborated to bring clinical trials to patients with an innovative decentralized clinical trial (DCT) solution.
Note: Tables for North America, Europe, Asia Pacific, South America and Middle East & Africa Regions are also represented in the same manner as above.