市场调查报告书
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2030 年 3D 细胞培养支架市场预测:按类型、用途和地区分類的全球分析3D Cell Culture Scaffold Market Forecasts to 2030 - Global Analysis By Type (Fiber, Hydrogel, Decellularized Scaffolds, Synthetic Polymers and Other Types), Application and By Geography |
根据 Stratistics MRC 的数据,全球 3D 细胞培养支架市场预计在预测期内将以 17.0% 的年复合成长率成长。
涉及三维(3D)细胞培养支架或基质的製造、销售和应用的全球产业被称为「3D细胞培养支架市场」。这些支架为细胞在三个维度上的发育、增殖和分化提供了有利的环境,与活体组织和器官中的条件非常相似。该市场包括各种合成聚合物、去细胞组织、水凝胶以及用于製造这些 3D 结构的其他材料和技术。
根据美国国立卫生研究院的数据,2020 年各种生物工程技术的总投资达 5,646 美元,高于 2019 年的 5,091 美元。根据美国卫生资源与服务管理局网站「organdonor.gov」显示,截至2021年10月,2020年美国等待器官移植的患者人数为107,103人。
人们对再生医学和组织工程应用的兴趣日益浓厚,为 3D 细胞培养支架促进生产用于移植的功能性组织和器官提供了机会。此外,药物开发中对更可靠的体外模型的需求不断增长,并且有机会建立更好的预测工具来测试药物功效和安全性。
由于支架材料和技术多种多样,很难为使用 3D 细胞培养支架的研究创建标准化方案。然而,由于它们比传统的 2D 培养技术更昂贵,因此3D 细胞培养支架和相关技术可能不会被广泛使用,特别是在资源有限的环境中。
随着 3D 细胞培养技术(包括基于支架的方法)的不断发展,体外细胞模型的准确性和生理有效性正在提高,从而增加了对支架的需求。此外,在癌症研究和药物试验中,基于支架的 3D 细胞培养模型可以实现更复杂、更真实的肿瘤模型,从而带来更好的治疗方法。
我们的 3D 细胞培养支架业务受到法规延误和成本增加的影响,特别是在用于药物测试和安全评估时。复杂的法规可能适用于 3D 细胞培养模型的使用,特别是在药物开发和毒性测试中。遵守这些法规并获得必要的核准可能需要大量的资源和时间。
由于全球供应线中断,疫情影响了製造 3D 细胞培养支架的基本材料和组件的供应。结果,製造商遭遇了延误和成本增加。由于经济不确定性,疫情期间研发部门的预算限制可能影响了 3D 细胞培养支架的投资。
预计合成聚合物领域在预测期内将占据最大份额。合成聚合物领域是 3D 细胞培养支架市场的关键结构要素,提供各种具有特定品质的工程材料,用于开发 3D 细胞培养环境。此外,合成聚合物由于其多功能性和生物相容性而非常重要,可以为个体化治疗创造复杂的细胞培养条件。合成聚合物透过促进功能组织和器官的发育,为推进再生医学提供了机会。
预计生物製药领域的年复合成长率最高。生物製药公司使用 3D 细胞培养支架来加速药物研发发现和开发过程。这些支架能够更准确地模拟体内情况,并能够更准确地评估候选药物的功效和安全性。此外,它对于创建生理上准确的细胞模型以用于毒性、癌症和标靶药物设计的研究至关重要。 3D 细胞培养支架市场正在帮助生物製药公司追求个人化医疗,让他们可以根据个别患者的反应来客製化药物。
亚太地区所占比例最高。随着该地区发展成为医疗旅游和高科技医疗服务中心,依赖 3D 细胞培养模型的精准医疗和组织再生变得越来越重要。此外,中国和印度等国家的强劲经济成长正在推动医疗保健和生命科学领域的投资,从而推动对尖端细胞培养技术的需求。
亚太地区预计将快速成长。由于该地区心血管疾病的流行,血管生物学研究和 3D 细胞培养支架的製造正在进行中,以更好地了解这些疾病并制定治疗方法。此外,亚太地区的製药部门正在使用 3D 细胞培养模型来测试心血管疗法并评估它们如何影响血管生物学,以帮助药物开发。
According to Stratistics MRC, the Global 3D Cell Culture Scaffold Market is expected to grow at a CAGR of 17.0% during the forecast period. The global industry for the manufacture, sale, and application of three-dimensional (3D) cell culture scaffolds or matrices is known as the "3D Cell Culture Scaffold Market." These scaffolds offer an environment that is favorable to cell development, proliferation, and differentiation in three dimensions and closely resembles the circumstances found in living tissues and organs. The market includes a wide range of synthetic polymers, decellularized tissues, hydrogels, and other materials and technologies that are used to produce these 3D structures.
According to the National Institute of Health, in 2020, the total investment in various bio engineering technologies amounted to USD 5,646, an increase from USD 5,091 in 2019. According to the organdonor.gov website of the United States Health Resources and Services Administration, in October 2021, 107,103 patients were on the national organ transplant waiting list in the year 2020.
Opportunities for 3D cell culture scaffolds to promote the production of functional tissues and organs for transplantation are offered by the growing interest in regenerative medicine and tissue engineering applications. Additionally, the market acquires from the growing demand for more reliable in vitro models in drug development, providing the chance to build better prediction tools for testing medication efficacy and safety.
Due to the wide range of scaffold materials and technologies available, creating standardized protocols for 3D cell culture scaffold-based research can be difficult. However, they can be more expensive than conventional 2D culture techniques, 3D cell culture scaffolds and related technologies may not be as widely used, especially in environments with limited resources.
The accuracy and physiological relevance of in vitro cell models are being improved by ongoing developments in 3D cell culture techniques, including scaffold-based approaches, which are increasing the demand for scaffolds. Additionally, for cancer research and medication testing, 3D cell culture models using scaffolds allow for more complicated and realistic tumor models, which leads to better therapeutic approaches.
Regulations can cause delays and higher costs in the 3D cell culture scaffold business, particularly when utilized for drug testing and safety evaluations. Complex regulatory regulations may apply to the use of 3D cell culture models, particularly in drug development and toxicity testing. It can take a lot of resources and time to comply with these rules and get the required approvals.
The pandemic affected the availability of essential materials and components needed to produce 3D cell culture scaffolds by disrupting global supply lines. Manufacturers experienced delays and higher expenses as a result. Budget restrictions in the research and development divisions during the pandemic were caused by economic uncertainty, which might have had an impact on investments in 3D cell culture scaffolds.
Synthetic Polymers segment is expected to hold the largest share over the forecast period. A crucial component of the market for 3D cell culture scaffolds, the synthetic polymer sector provides an extensive range of designed materials with specific qualities for developing three-dimensional cell culture settings. Additionally, in order to create complex cell culture conditions for personalized treatment, synthetic polymers are crucial because of their versatility and biocompatibility. They provide the chance for advancements in regenerative medicine by facilitating the development of functioning tissues and organs.
Biopharmaceutical segment is expected to have the highest CAGR. 3D cell culture scaffolds are used by biopharmaceutical businesses to accelerate the drug discovery and development process. These scaffolds offer a more exact approximation of in vivo circumstances, enabling more accurate efficacy and safety assessments of drug candidates. Additionally, they are crucial in the production of physiologically accurate cell models for inquiries on toxicity, cancer, and the design of targeted medicines. The market for 3D cell culture scaffolds aids biopharmaceutical companies in the pursuit of personalized medicine by enabling them to customize medicines based on individual patient responses.
The largest share was held by the Asia-Pacific area. Precision medicine and tissue regeneration, which rely on 3D cell culture models, are becoming more and more important as the area develops as a center for medical tourism and high-tech healthcare services. Additionally, investments in healthcare and life sciences are being fueled by the robust economic growth of nations like China and India, which is raising the demand for cutting-edge cell culture technologies.
Asia Pacific region is expected to grow rapidly. The prevalence of cardiovascular disorders in the area has prompted an examination of vascular biology and the creation of 3D cell culture scaffold in an effort to better understand these illnesses and create therapeutic remedies. Moreover, the Asia Pacific region's pharmaceutical sector uses 3D cell culture models to test cardiovascular medications and assess how they affect vascular biology, which helps in drug development.
Some of the key players in 3D Cell Culture Scaffold Market include: 3D Biotek, Corning Incorporated, Greiner Bio-One, InSphero AG, Lonza Group, Merck KGaA, N3d Bioscience, Nanofiber Solutions, Reprocell Incorporated, Synthecon Incorporated, TARA Biosystems and Thermo Fisher Scientific.
In October 2023, Thermo Fisher expands US manufacturing plant to support biologics. The US-based biotechnology and medical equipment company has added multiple biologic manufacturing facilities to accommodate a growing demand for these therapies.
In October 2023, Thermo Fisher Scientific, the world leader in serving science, expanded its manufacturing capacity in St. Louis to support biologic therapies for diseases ranging from cancers to auto immune conditions to rare genetic disorders.