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2030 年 RNA 定序市场预测:按产品、服务、技术、应用、最终用户和地区进行的全球分析RNA Sequencing Market Forecasts to 2030 - Global Analysis By Product, Service, Technology, Application, End User and By Geography |
根据 Stratistics MRC 的数据,全球 RNA 定序市场在预测期内将以 21.4% 的复合年增长率成长。
RNA 定序(也称为 RNA-Seq)是一种基因组方法,用于检测和定量分析生物样本中的信使 RNA 分子,可用于研究细胞反应。 RNA 定序利用高通量定序方法的力量来深入了解细胞的转录组。此方法对于研究基因表现模式、了解细胞过程、识别生物标记以及探索各种研究领域(包括遗传学、基因组学、分子生物学和医学)的疾病机制至关重要。
根据罕见疾病国际组织和 EURORDIS 的数据,罕见疾病目前影响着全球人口的 3.5% 至 5.9%。
精准医疗需求不断成长
RNA测序能够在分子层面上全面分析个体的遗传资讯,在精准医学中发挥重要作用。 RNA 定序有助于识别影响疾病易感性、疾病进展和治疗反应的特定基因突变、基因表现模式和遗传标记。这种全面的知识可以实现个人化的医疗干预,例如标靶治疗和基于个人基因谱的治疗。此外,随着精准医学的加速发展,RNA 定序解释复杂遗传资料的能力变得越来越重要。这将促进 RNA 定序融入临床照护和研究,推动 RNA 定序市场的成长。
资料分析挑战
由于资料量庞大、任务复杂,资料分析的复杂性是RNA定序市场的抑制因素。 RNA-seq资料分析需要先进的计算基础设施、专门的演算法和生物资讯学专业知识来准确解释基因表现模式。跨平台标准化分析方法以确保结果一致是一项挑战,并且会影响资料可靠性。缺乏熟练的分析师和不断发展的工具使这一过程更加复杂。因此,市场需求将受到限制。
生物资讯学创新
生物资讯工具和演算法的进步使得复杂 RNA-seq资料的分析、解释和视觉化变得更加复杂。这些创新提高了资料准确性,并促进基因表现模式、剪接变异体和非编码 RNA 的识别,使研究人员能够获得有意义的生物学见解。此外,改进的软体解决方案简化了资料处理,并使更广泛的用户可以进行分析。持续的生物资讯学创新也促进了新分析方法的发展,促进了RNA定序在不同研究领域、临床诊断和药物开发中更深入的理解和应用。
资料安全和隐私问题
基因组资料的快速成长引发了对诈欺的存取、滥用和敏感遗传资讯外洩的担忧。由于 RNA 定序会产生广泛的个体遗传图谱,因此确保这些资料的机密性和安全处理至关重要。潜在风险包括未经授权的资料存取、资讯盗窃以及共用基因组资讯的道德困境。这些担忧会破坏社会信任,并可能导致对资料共用和使用的监管限制。
COVID-19 大流行对 RNA 定序市场产生了重大影响。儘管最初遇到供应链中断和实验室限制等障碍,但对 RNA 定序的需求迅速增长。研究人员加速了基因组研究,以了解病毒、开发疫苗并确定潜在的治疗方法。该行业见证了自动化和远端解决方案的发展,以减少操作困难。此外,此次疫情凸显了RNA定序在感染疾病、癌症和个人化医疗研究中的重要性,促进了市场应用和解决方案的持续扩展和多样化。
离子半导体定序领域预计将在预测期内成为最大的领域
据估计,离子半导体序列段所占占有率最大。离子半导体定序是一种 DNA 定序技术,依赖 DNA 聚合过程中产生的氢离子的识别。此技术可检测核苷酸掺入不断生长的 DNA 链时所发生的 pH 值变化。离子半导体定序以其快速处理、经济实惠和适合特定定序应用而闻名。此外,可以透过测量离子浓度的变化来精确识别 DNA 序列,从而实现 RNA 分析以进行基因表现研究、变异检测和理解生物过程。
学术和研究机构部门预计在预测期内复合年增长率最高
学术和研究机构部门预计在预测期内将出现良好成长。学术和研究机构包括积极从事科学研究和基因组研究的教育机构、大学和研究机构。这些机构透过进行基础研究、探索新应用和检验调查方法,在推进 RNA 定序技术方面发挥着至关重要的作用。他们将 RNA 定序用于多种目的,包括破解基因表现模式、识别生物标记、了解疾病机制以及开发治疗性介入。因此,细分市场成长的需求正在增加。
由于精准医疗的日益普及、政府支持基因组研究的倡议以及学术机构和生物技术公司之间研究合作的激增,亚太地区在预测期内占据了最大的市场占有率。测序成本降低、临床诊断应用增加以及主要市场参与企业的存在等因素正在推动市场成长。在个人化医疗需求不断增长和生物资讯学进步的推动下,亚太地区 RNA 定序市场有望持续扩张和创新,塑造该地区医疗保健和生物研究的未来。
由于 RNA 定序技术的接受度不断提高,预计北美在预测期内将出现有益成长。该地区的特点是广泛的研究活动、雄厚的资金筹措和有利的监管环境。基因组学研究投资的增加、学术机构和行业参与企业之间的合作以及精准医疗的兴起等因素正在推动市场成长。药物研发、诊断和个人化医疗对 RNA 定序的高需求,以及定序技术和资料分析工具的进步,正在推动市场向前发展。
According to Stratistics MRC, the Global RNA Sequencing Market is growing at a CAGR of 21.4% during the forecast period. RNA sequencing, also known as RNA-Seq, is a genomic approach for the detection and quantitative analysis of messenger RNA molecules in a biological sample and is useful for studying cellular responses. RNA sequencing uses the capabilities of high-throughput sequencing methods to provide insight into the transcriptome of a cell. This method is crucial for studying gene expression patterns, understanding cellular processes, identifying biomarkers, and exploring disease mechanisms in various research areas, including genetics, genomics, molecular biology, and medicine.
According to Rare Diseases International, and EURORDIS, rare diseases currently affect at any point in time 3.5% - 5.9% of the worldwide population; 72% are genetic, of which around 70% start in childhood.
Growing demand for precision medicine
RNA sequencing plays a crucial role in precision medicine by enabling comprehensive analysis of an individual's genetic information at the molecular level. Identification of particular genetic variants, patterns of gene expression and genetic markers that impact the susceptibility to disease, its progression, and its response to treatment are rendered easier by it. This comprehensive knowledge makes it possible to implement individualised healthcare interventions, such as targeted therapies and therapies based on a person's genetic profile. Moreover, the capacity of RNA sequencing to interpret complex genetic data has become increasingly essential as precision medicine gains pace. This will encourage the integration of RNA sequencing into clinical care and research, which will fuel market growth for RNA sequencing.
Data analysis challenges
Data analysis complexities pose a restraint in the RNA sequencing market due to the immense data volume and intricacies involved. Analysing RNA sequencing data demands advanced computational infrastructure, specialised algorithms, and bioinformatics expertise to interpret gene expression patterns accurately. Standardising analysis methods across platforms for result consistency is challenging, impacting data reliability. A shortage of skilled analysts and evolving tools further complicate the process. Therefore, it will limit market demand.
Innovation in bioinformatics
Advancements in bioinformatics tools and algorithms enable more sophisticated analysis, interpretation, and visualisation of complex RNA sequencing data. These innovations enhance data accuracy, facilitate the identification of gene expression patterns, splice variants, and non-coding RNAs, and empower researchers to extract meaningful biological insights. Furthermore, improved software solutions streamline data processing, making analysis more accessible to a wider range of users. Continual bioinformatics innovation also drives the development of novel analytical methods, fostering deeper understanding and application of RNA sequencing in diverse research fields, clinical diagnostics, and drug development.
Data security and privacy concerns
The exponential growth in genomic data raises apprehensions about unauthorised access, misuse, and breaches of sensitive genetic information. As RNA sequencing generates extensive personal genetic profiles, ensuring the confidentiality and secure handling of this data becomes paramount. Potential risks include unauthorised data access, identity breaches, and ethical dilemmas related to sharing genomic information. These concerns could erode public trust, resulting in regulatory restrictions on data sharing and utilization.
The COVID-19 pandemic had a significant impact on the RNA sequencing market. Despite the initial hurdles imposed by disrupted supply chains and restricted laboratories, demand for RNA sequencing quickly increased. Researchers accelerated genomic studies to understand the virus, develop vaccines, and identify potential treatments. The industry witnessed an evolution in the direction of automated and remote solutions to lessen operational difficulties. Furthermore, the pandemic underscored the significance of RNA sequencing in the investigation of infectious diseases, cancer, and personalised medicine, hence promoting sustained expansion and variety in the market's applications and solutions.
The Ion Semiconductor Sequencing segment is expected to be the largest during the forecast period
The Ion Semiconductor Sequencing segment is estimated to hold the largest share. Ion semiconductor sequencing is a technique for sequencing DNA that relies on the identification of hydrogen ions generated during DNA polymerization. This method involves detecting changes in pH levels generated as nucleotides are incorporated into a growing DNA strand. Sequencing from Ion Semiconductor is renowned for its quick processing, affordability, and fit for specific sequencing applications. Additionally, it can precisely identify DNA sequences by measuring changes in ion concentrations, making RNA analysis for gene expression research, variant detection, and comprehending biological processes possible.
The Academic and Research Institutes segment is expected to have the highest CAGR during the forecast period
The Academic and Research Institutes segment is anticipated to have lucrative growth during the forecast period. The Academic and Research Institutes comprise educational institutions, universities, and research organisations actively engaged in scientific investigations and genomic studies. These entities play a pivotal role in advancing RNA sequencing technologies by conducting fundamental research, exploring novel applications, and validating sequencing methodologies. They leverage RNA sequencing for diverse purposes, including deciphering gene expression patterns, identifying biomarkers, understanding disease mechanisms, and developing therapeutic interventions. Thus, there is an increasing demand for segment growth.
Asia Pacific commanded the largest market share during the extrapolated period owing to rising adoption of precision medicine, government initiatives supporting genomics research, and a surge in collaborations among academic institutions and biotech firms. Factors like reduced sequencing costs, expanding applications in clinical diagnostics, and the presence of key market players are driving market growth. With growing demand for personalised medicine and advancements in bioinformatics, the Asia-Pacific RNA sequencing market is poised for continuous expansion and innovation, shaping the future of healthcare and biological research in the region.
North America is expected to witness profitable growth over the projection period, owing to the rising acceptance for RNA sequencing techniques. It is characterised by extensive research initiatives, robust funding, and a favourable regulatory landscape. Factors such as increasing investments in genomics research, collaborations between academic institutions and industry players, and the prominence of precision medicine drive market growth. The high demand for RNA sequencing in drug discovery, diagnostics, and personalised medicine, along with advancements in sequencing techniques and data analysis tools, propels the market forward.
Some of the key players in the RNA Sequencing Market include Thermo Fischer Scientific, Illumina, Tecan Genomics Inc., Agilent Technologies Inc., F. Hoffmann-La Roche Ltd, PerkinElmer Inc., GE Healthcare, Bio-Rad Laboratories Inc., Eurofins Scientific, Sigma Aldrich, Admera Health, CD Genomics, Biogazelle, Creative Biogene, LC Sciences, IGA Technology , Lexogen, Otogenetics, Novogene, Yaazh Xenomic and Oxford Nanopore Technologies.
In August 2023, Thermo Fisher Scientific, the world leader in serving science, announced the launch of a new chromosomal microarray designed to improve cytogenetic research lab productivity, efficiency and profitability with an industry-leading two-day turnaround time.
In May 2023, Thermo Fisher Scientific, the world leader in serving science, expanded its manufacturing capacity in St. Louis to support biologic therapies for diseases ranging from cancers to auto immune conditions to rare genetic disorders.
In March 2021, Thermo Fisher Scientific Inc., declared the introduction of the Thermo Scientific Aerosol Sense Sampler, a novel surveillance solution planned to transfer speedy and greatly trustworthy insight into the existence of in-air pathogens, inclusive of SARS-CoV-2. Individual testing will persist in being essential in the COVID-19 pandemic response owing to its ability to allow and apprise clinical diagnoses, patient triage, and treatment decisions.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.