市场调查报告书
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2030 年荷尔蒙替代疗法市场预测:按治疗类型、给药途径、适应症、配销通路和地区进行的全球分析Hormone Replacement Therapy Market Forecasts to 2030 - Global Analysis By Therapy Type, By Route of Administration, Indication, Distribution Channel and By Geography |
根据 Stratistics MRC 的数据,2023 年全球荷尔蒙替代疗法市场规模将达到 358 亿美元,预计 2030 年将达到 621 亿美元,预测期内复合年增长率为 8.2%。
荷尔蒙替代疗法(HRT)是一种医疗程序,旨在为因老龄化、更年期或其他疾病而荷尔蒙平衡而被破坏的人补充或替代雌激素、黄体酮和睪固酮等荷尔蒙。荷尔蒙替代疗法可以缓解女性的潮热、情绪低落和阴道干燥等症状,也可以解决男性的荷尔蒙缺乏问题。
根据世界卫生组织(WHO)预测,到2030年,全球整体六分之一的人口将超过60岁,到2050年,预计老年人口将达到21亿。
各种荷尔蒙失调的盛行率不断增加
各种荷尔蒙失调的盛行率不断增加是荷尔蒙替代疗法市场的关键驱动因素。人口老化、生活方式的改变和环境影响等因素导致荷尔蒙失衡、女性更年期相关症状和男性更年期的发生率增加。甲状腺机能低下症、更年期和激素缺乏等疾病正在推动对荷尔蒙替代疗法的需求。越来越多的患者寻求缓解与荷尔蒙失调相关的症状和併发症,推动了荷尔蒙替代疗法市场的成长。
荷尔蒙替代疗法高成本
荷尔蒙替代治疗药物、咨询和后续观察的费用可能很高,影响了许多患者的经济负担。此外,保险范围和报销限制通常会导致自付费用并限制可及性。这些财务障碍可能会阻止人们寻求或继续荷尔蒙替代疗法,影响治疗医嘱遵从性和整体市场成长。
透过新的输送系统增加药物开发
创新的给药方法,如经皮吸收贴片、皮下植入和生物分解性的微球,提高了治疗效果、病患依从性和便利性。与传统口服製剂相比,这些进步导致给药更精确、荷尔蒙释放更稳定、副作用更少。此外,透过改善治疗结果并满足寻求荷尔蒙替代疗法的个人的多样化需求,我们正在吸引患者,扩大治疗选择并推动市场成长。
治疗的副作用
荷尔蒙疗法,尤其是雌激素疗法,会增加血栓、中风、乳癌和心血管併发症的风险。这些风险因年龄、给药、治疗持续时间和个人健康史等因素而异。对这些副作用的担忧导致了 HRT 使用量的下降以及对其长期安全性的质疑,从而影响了市场成长。
COVID-19 大流行对市场产生了各种影响。医疗保健服务中断,包括前往诊所的机会有限和选择性手术减少,影响了 HRT 处方和患者咨询。由于健康问题加剧,我推迟了接受荷尔蒙治疗。然而,大流行期间对更年期症状和心理健康问题的认识提高可能推动了对荷尔蒙替代疗法的需求。
预测期内,更年期族群预计将是最大的
预计更年期细分市场将成为预测期内最大的细分市场。随着人口老化,更多女性将进入闭经并寻求治疗方法来控制更年期症状,如潮热、盗汗和情绪变化。此外,针对更年期症状的荷尔蒙替代疗法配方和给药方法的进步也促进了这一领域的发展。
人体生长荷尔蒙替代疗法预计在预测期内复合年增长率最高
在预测期内,由于人们对生长激素缺乏症的认识不断提高,以及成人和儿童荷尔蒙失衡发生率的增加,人体生长荷尔蒙(HGH)替代疗法领域将保持强劲,预计将推动对HGH 疗法的需求增长。此外,生物技术的重大发展导致了创新 HGH 配方和输送方法的开发,以及在解决各种健康状况方面的不断扩大的应用,是预测该领域显着增长的关键因素。
由于其先进的医疗基础设施、高昂的医疗成本以及对研发的重视,预计北美将占据最大的市场占有率。此外,荷尔蒙失衡的普遍存在以及寻求荷尔蒙治疗的人口老化也促进了市场的显着增长。有利的报销政策和主要市场参与者的存在进一步强化了北美市场的主导地位。
由于人口老化以及人们对更年期症状和荷尔蒙失调的认识不断增强,预计亚太地区的市场将出现强劲增长。此外,快速的都市化、生活方式的改变和日益增长的医疗保健问题正在增加荷尔蒙失衡的盛行率,从而促进市场成长。此外,医疗基础设施的改善、可支配收入的增加以及不断发展的法规结构正在促进更便利的医疗服务,从而推动亚太地区的大幅成长。
According to Stratistics MRC, the Global Hormone Replacement Therapy Market is accounted for $35.8 billion in 2023 and is expected to reach $62.1 billion by 2030 growing at a CAGR of 8.2% during the forecast period. Hormone Replacement Therapy (HRT) involves medical treatments aimed at supplementing or replacing hormones, such as estrogen, progesterone, or testosterone, in individuals experiencing hormonal imbalances due to aging, menopause, or other conditions. HRT can alleviate symptoms like hot flashes, mood swings, and vaginal dryness in women and address hormonal deficiencies in men.
According to World Health Organization (WHO), it is estimated that by 2030, 1 in 6 people will be aged 60 years or more globally and by 2050, the geriatric population is expected to reach 2.1 billion worldwide.
Growing prevalence of various hormonal disorders
The increasing prevalence of diverse hormonal disorders serves as a significant driver in the hormone replacement therapy market. Factors such as aging populations, lifestyle changes, and environmental influences contribute to rising incidences of hormonal imbalances, menopause-related symptoms in women and andropause in men. Conditions like hypothyroidism, menopausal symptoms and hormonal deficiencies drive the demand for HRT. This growing patient pool seeking relief from symptoms and complications associated with hormonal disorders fuels the expansion of the hormone replacement therapy market.
High cost of hormone replacement therapy
Expenses for hormone replacement therapy medications, consultations and follow-up visits can be substantial, impacting affordability for many patients. Moreover, insurance coverage and reimbursement limitations often lead to out-of-pocket expenses, limiting accessibility. This financial barrier can deter individuals from seeking or continuing hormone replacement therapy, affecting treatment adherence and overall market growth.
Rise in drug development with novel delivery systems
Innovative delivery methods, such as transdermal patches, subcutaneous implants and biodegradable microspheres, enhance treatment efficacy, patient compliance and convenience. These advancements offer precise dosing, steady hormone release and reduced side effects compared to traditional oral formulations. They also attract patient interest and expand treatment options, driving market growth by improving therapeutic outcomes and addressing the diverse needs of individuals seeking hormone replacement therapies.
Adverse effects of therapies
Hormone therapies, particularly estrogen-based ones, may elevate the risk of blood clots, stroke, breast cancer and cardiovascular complications. These risks vary based on factors like age, dosage, duration of therapy, and individual health history. Concerns about these adverse effects have led to a decline in HRT usage and raised questions about its long-term safety, impacting market growth.
The COVID-19 pandemic had varied impacts on the market. Disruptions in healthcare services, including limited access to clinics and reduced elective procedures, affected HRT prescriptions and patient consultations. Heightened health concerns led to delays in seeking hormonal therapies. However, increased awareness of menopausal symptoms and mental health issues during the pandemic might have driven demand for HRT.
The menopause segment is expected to be the largest during the forecast period
During the forecast period, the menopause segment is anticipated to become the largest in the market. As the population ages, the number of women entering menopause increases, leading to a larger demographic seeking therapies to manage menopausal symptoms like hot flashes, night sweats, and mood changes. Additionally, advancements in HRT formulations and delivery methods tailored specifically for menopausal symptoms contribute to the growth of this segment.
The human growth hormone replacement therapy segment is expected to have the highest CAGR during the forecast period
During the forecast period, the human growth hormone (HGH) replacement therapy segment is anticipated to experience robust growth owing to increased awareness of growth hormone deficiencies, coupled with rising instances of hormonal imbalances in adults and children, which is driving demand for HGH therapies. In addition, advancements in biotechnology, leading to the development of innovative HGH formulations and delivery methods, along with expanding applications in addressing various health conditions, are key contributors to the projected substantial growth in this segment.
North America is expected to witness the largest market share, due to the advanced healthcare infrastructure, high healthcare expenditure, and a significant emphasis on research and development. Moreover, the prevalence of hormonal imbalances, coupled with an aging population seeking hormone therapies, contributes to substantial market growth. Favorable reimbursement policies and the presence of key market players further reinforce North America's dominance in the market.
Asia Pacific is poised for robust growth in the market due to the region's expanding aging population, coupled with increasing awareness of menopausal symptoms and hormonal disorders. Additionally, rapid urbanization, lifestyle changes, and a growing focus on healthcare have heightened the prevalence of hormonal imbalances, propelling market growth. Moreover, improving healthcare infrastructure, rising disposable incomes and evolving regulatory frameworks are facilitating greater accessibility to fostering substantial growth in the Asia Pacific region.
Some of the key players in Hormone Replacement Therapy Market include AbbVie Inc., Acerus Pharmaceuticals, Amgen, Bausch Health Companies, Bayer AG, Eli Lilly and Company, Merck & Co., Mithra Pharmaceuticals SA, Mylan NV, Novartis AG, Novo Nordisk, Pfizer Inc., QuatRx Pharmaceuticals, Radius Health, Sanofi, Serum Institute of India, Teva Pharmaceutical Industries, TherapeuticsMD and Veru Inc.
In August 2022, Akorn announced that it had successfully received FDA approval for launching its Generic-Cetrorelix Acetate in the form of Injection (0.25 mg quantity). Cetrorelix is one of the most effective chemicals used in hormone replacement therapy as it totally blocks the adverse impacts of a natural hormone, known as GnRH or gonadotropin-releasing hormone.
In February 2022, MHLW of Japan approved NGENLA of Pfizer, Inc. and OPKO which is a long-lasting treatment for pediatric growth hormone deficiency. This strategic initiative helps the companies to expand their customer base in different geography and boost their revenue.