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市场调查报告书
商品编码
1401981
2030 年胜肽合成市场预测:按产品、技术、应用、最终用户和地区进行的全球分析Peptide Synthesis Market Forecasts to 2030 - Global Analysis By Product (Equipment, Reagents, Consumables and Other Products), Technology, Application, End User and By Geography |
根据Stratistics MRC预测,2023年全球胜肽合成市场规模将达51亿美元,预计2030年将达到102亿美元,预测期内复合年增长率为10.2%。
形成胜肽(透过胜肽键连接的胺基酸短链)的化学过程称为胜肽合成。胺基酸必须按照预定的顺序阶段组装,反应的控制通常需要保留特定的官能基。合成胜胜肽有多种方法,包括固相合成、溶液相合成和重组DNA技术。
据 ClinicalTrials.gov 称,正在开发 21 种胜肽药物来治疗 COVID-19,其中 15 种用于急性呼吸窘迫症候群(ARDS),这是一种肺部无法为身体重要器官提供足够氧气的疾病是一种合成胜胜肽,用于治疗SARS-COV-2感染引起的呼吸道疾病。
个体化药物的开发
随着个体化医疗的出现,胜肽合成领域预计将显着成长。个体化医疗的理念是透过根据特定患者情况客製化胜胜肽的能力来实现的。胜肽提供实现个体化治疗计划所需的标靶性、客製性和特异性。随着个人化医疗的不断发展和普及,对胜肽合成技术、服务和产品的需求预计将急剧增加。
有关给药的问题
由于胃肠道吸收较差,大多数治疗性胜肽透过肠胃外途径给药。胜肽药物的口服生物利用度有限,主要是由于全身性酵素的降解。此外,它们的大分子量和带电官能基会抑制吸收。由于这些特性,大多数给药胜肽的生物利用度有限且半衰期短。因此,这对市场来说是一个挑战。
罕见疾病治疗方法的进展
胜肽有可能治疗罕见疾病和不寻常的遗传问题。随着个体化医疗的出现,胜肽合成领域具有巨大的成长潜力。胜肽提供实现个体化治疗计划所需的标靶化、客製性和特异性。随着个人化医疗的不断发展和普及,对胜肽合成技术、服务和产品的需求预计将急剧增加。
精製和品管
为了使研究和治疗应用有效,必须获得高纯度的胜肽。高效液相层析(HPLC) 是一种精製技术,但它可能非常耗时,并且必须针对每个胜肽序列进行最佳化。需要采取品管步骤来确保合成的胜肽准确、一致和安全。对于市场来说,维持有效的精製程序和高品质标准可能很困难。
这次疫情扰乱了世界各地的供应线,影响了胜肽合成所需原料和设备的可得性。合成胜胜肽的总分布和可得性受到生产和出货延误的影响。大流行使医疗保健的重点发生了重大转变。对与 COVID-19 研究相关的一些胜肽类药物和疫苗的需求可能增加,而非必要医疗保健服务的中断可能会减少对其他胜肽产品的需求。
预计试剂细分市场在预测期内将是最大的
预计试剂细分市场将成为预测期内最大的细分市场。胜肽合成过程将胺基酸化学结合形成胜肽。透过使用促进更快、更有效胜肽键形成的特定化学物质可以减少合成时间。透过减少副作用和污染物,并使用适当的试剂,您可以获得更高纯度的胜肽。某些试剂具有高度选择性,因此有助于胺基酸的精确偶联,而不会发生不良反应。
製药和生物技术公司领域预计在预测期内复合年增长率最高
製药和生物技术公司领域预计在预测期内复合年增长率最高。胜肽疗法因其低毒性、高效和成本效益而成为更多研究和开发的主题。胜肽合成仪的快速技术进步和强大的胜肽治疗产品线是推动製药和生物技术公司胜肽合成产业的主要因素。
预计北美在预测期内将占据最大的市场占有率。定制疗法生产的扩大、基因组学和蛋白质组学领域的深入研究以及对创建基于结构的药物设计的投资增加正在支持该地区的市场。此外,由于人们对易于使用的胜肽合成方法的认识不断提高,预计市场将会扩大。
预计亚太地区在预测期内将维持最高的复合年增长率。由于主要参与者的投资增加,预计该市场将显着开拓。此外,该地区市场的推动因素包括新型胜肽疗法意识的增强、医疗保健成本的上升、更先进的医疗设施的可用性以及行业主要参与者为创造新的胜肽合成而进行的大量投资技术,预计将随着投资而成长。
According to Stratistics MRC, the Global Peptide Synthesis Market is accounted for $5.1 billion in 2023 and is expected to reach $10.2 billion by 2030 growing at a CAGR of 10.2% during the forecast period. The chemical process of forming peptides, which are short chains of amino acids joined by peptide bonds, is known as peptide synthesis. It entails assembling amino acids step-by-step in a predetermined order, and controlling the reaction frequently necessitates the preservation of particular functional groups. There are several ways to synthesize peptides, including solid-phase synthesis, solution-phase synthesis, and recombinant DNA technology.
According to Clinical Trials.gov, 21 peptide drugs were in development for the treatment of COVID-19, including 15 synthetic peptides for acute respiratory distress syndrome (ARDS), a life-threatening condition in which the lungs are unable to provide enough oxygen to the body's vital organs, and other respiratory illnesses caused by SARS-Cov-2 infection.
Development of personalized medicines
The peptide synthesis sector has significant growth prospects due to the emergence of customized medicine. The idea of customized medicine is made possible by the ability to customize peptides to fit certain patient profiles. They provide the necessary targeting, customisation, and specificity to enable individualized treatment plans. It is anticipated that the need for peptide synthesis technology, services, and products will increase dramatically as personalized medicine continues to develop and gain popularity.
Problems related to the administrative route
The majority of therapeutic peptides are administered by the parenteral route because of insufficient absorption from the gastrointestinal tract. Peptide medications have a limited oral bioavailability mostly due to pre-systemic enzymatic breakdown. Additionally, the large molecular weight and charged functional groups of these medicines sometimes impede their absorption. These features result in the majority of peptides taken orally having limited bioavailability and brief half-lives. Hence, it can be considered a challenge for the market.
Advancement in therapeutics for rare diseases
Peptides could be able to cure orphan illnesses and unusual genetic problems. The peptide synthesis sector has significant growth prospects due to the emergence of customized medicine. Peptides provide the necessary targeting, customisation, and specificity to enable individualized treatment plans. It is anticipated that the need for peptide synthesis technology, services, and products will increase dramatically as personalized medicine continues to develop and gain popularity.
Purification and quality control
Peptides must be obtained with a high degree of purity in order for research and therapeutic applications to be effective. High-performance liquid chromatography (HPLC) is one of the purification techniques that might take a long time and need to be optimized for every peptide sequence. For synthesized peptides to be accurate, consistent, and safe, quality control procedures are necessary. The market may find it difficult to maintain effective purification procedures and high standards of quality.
The pandemic affected the availability of raw materials and equipment required for peptide synthesis by upsetting supply lines around the world. The total distribution and availability of synthesized peptides were impacted by production and shipping delays. The pandemic caused a major shift in the focus of healthcare. Demand for some peptide-based medications or vaccines associated with COVID-19 research may have increased, while interruptions in non-essential healthcare services may have resulted in a decline in demand for other peptide products.
The reagents segment is expected to be the largest during the forecast period
The reagents segment is expected to be the largest during the forecast period. The process of peptide synthesis entails joining amino acids chemically to form peptides. Synthesis times can be shortened by using certain chemicals that promote quicker and more effective peptide bond formation. By reducing side effects and contaminants, using the right reagent can result in a peptide that is more pure. Certain reagents help with the precise coupling of amino acids without producing undesirable reactions since they are very selective.
The pharmaceutical and biotechnology companies segment is expected to have the highest CAGR during the forecast period
The pharmaceutical and biotechnology companies segment is expected to have the highest CAGR during the forecast period. Peptide treatments are the subject of more study and development because they are less toxic, efficacious, and cost-effective. Rapid technical improvements in peptide synthesizers and a robust pipeline of peptide therapies are the main factors driving the peptide synthesis industry in pharmaceutical and biotechnology firms.
North America is projected to hold the largest market share during the forecast period. Growth in the production of customized therapies, substantial research in the fields of genomics and proteomics, and greater investments in the creation of structure-based medicine designs have all helped the regional market. Additionally, the market will expand due to the increased awareness of the accessible peptide synthesis methods.
Asia Pacific is projected to hold the highest CAGR over the forecast period. The market is expected to develop significantly as a result of the increase in investments made by important players. Furthermore, it is expected that the region's market will grow due to rising awareness of novel peptide treatments, rising healthcare costs, the availability of more cutting-edge healthcare facilities, and significant investments made by the major players in the industry to create new peptide synthesis technologies.
Some of the key players in Peptide Synthesis market include Biotage, Genscript Biotech, Thermo Fisher Scientific, Merck KGaA, Creative Diagnostics, CEM Corporation, Bachem Holdings, PuroSynth, Syngene, Lonza, Polypeptide Group, Novo Nordisk A/S, MP Biomedicals and Evonik.
In January 2023, Merck announced an agreement to acquire the peptide synthesis company Asymchem. This acquisition will give Merck access to Asymchem's expertise in peptide synthesis and its global manufacturing network.
In December 2022, Thermo Fisher announced an agreement to acquire the peptide synthesis company Protagen. This acquisition will give Thermo Fisher access to Protagen's expertise in peptide synthesis and its global manufacturing network.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.