市场调查报告书
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1402015
聚合酶炼式反应市场预测至 2030 年:按产品、应用、最终用户和地区进行的全球分析Polymerase Chain Reaction Market Forecasts to 2030 - Global Analysis By Product, Application, End User and By Geography |
根据 Stratistics MRC 的数据,2023 年全球聚合酶炼式反应市场规模为 89 亿美元,预计在预测期内将以 11.5% 的复合年增长率增长,到 2030 年达到 191 亿美元。
聚合酶炼式反应是一种分子技术,透过体外扩增产生数百万个特定 DNA 链的拷贝。 PCR 灵敏度很高,可以检测微量 DNA。这在目标 DNA 浓度较低的应用中尤其有利,例如在某些疾病的早期阶段或在分析法医学样本中的微量 DNA 时。
据印度医学研究委员会 (ICMR) 称,到 2027 年,印度的癌症病例将增加 12%。
基因检测需求不断成长
基因检测需求的不断增长是聚合酶炼式反应市场的关键驱动因素。基因测试涉及分析个体的 DNA,以识别遗传变异、突变和基因表现模式。 PCR 透过扩增特定 DNA 序列以进行进一步分析,在此过程中发挥重要作用。此外,基因测试在那些对自己的血统感到好奇并想要探索自己的遗传遗产的人中越来越受欢迎。因此,这些进步正在扩大 PCR 在基因检测中的应用,并促进 PCR 市场的成长。
高成本
PCR 设备、试剂和消耗品的初始投资,加上对熟练人员的需求,增加了整体成本,特别是对于较小的诊断设施和实验室。 PCR 设备的复杂性和持续的品管要求进一步增加了营运成本。此外,PCR 检测的成本会对患者和医疗保健系统造成负担,影响尖端诊断服务的负担能力和公平分配。因此,高成本是市场拓展的主要障碍。
技术进步
即时 PCR 可以即时检测和定量 PCR 扩增,在扩增过程中提供即时结果。这种即时监测可以实现更快、更准确的分析,使其在临床诊断、基因检测和研究等领域发挥作用。此外,PCR 设备技术的进步促进了更容易使用的自动化系统的开发。整合热聚合酵素连锁反应热迴圈仪具有先进的温度控制演算法和直觉的软体介面,使包括研究人员、临床医生和技术人员在内的广大用户更容易使用 PCR。这些技术进步是加速市场需求的主要因素。
复杂性与专业知识
PCR技术涉及的各个步骤,包括引子设计、反应条件最佳化和资料分析,都需要一定程度的技术知识和训练。 PCR 方案需要仔细设计和选择专门特异性感兴趣的 DNA 区域的引子。设计具有适当熔解温度的引子、避免二级结构并最大限度地减少引子-二聚体相互作用是一项挑战。进行聚合酶链反应所需的复杂性和技术专业知识是聚合酶链反应市场的抑制因素。
COVID-19 大流行严重影响了聚合酶炼式反应市场的成长。临床诊断细分市场需求的不断增长对 PCR 市场产生了积极影响。医学专家建议出现 COVID-19 症状的人接受诊断测试,几乎所有这些测试都使用 RT-PCR,因为当局不建议进行病毒培养测试。许多製药和生物技术公司的研发部门都专注于寻找用于治疗 COVID-19 的新分子和先导化合物。
预计试剂细分市场在预测期内将是最大的
试剂部分估计占最大占有率。 PCR 试剂包括多种化学物质,包括 DNA 聚合酶、引子、核苷酸和缓衝液,每种物质在反应中都扮演着特定的角色。 DNA聚合酶,例如Taq聚合酶,催化互补DNA链的合成,引子提供DNA扩增的起点。核苷酸作为新合成 DNA 链的建构模组,缓衝液维持酵素活性的最佳 pH 条件。为了确保 PCR 反应的准确性和效率,对高品质和可靠试剂的需求至关重要。
预计诊断中心细分市场在预测期内复合年增长率最高
预计诊断中心部门在预测期内将出现良好的成长。 PCR技术广泛应用于诊断中心,用于检测各种疾病,包括感染疾病、遗传疾病和癌症。诊断中心利用 PCR 的高灵敏度和特异性来识别和量化特定的 DNA 或 RNA 序列,有助于早期、准确地诊断疾病。 PCR 的多功能性使诊断中心能够提供广泛的测试,有助于全面的患者照护。
在估计期间,北美占据了最大的市场占有率。高频率的疾病、该地区重要参与企业的存在、有利的法规以及与医疗保健基础设施进步相关的众多政府倡议有助于该地区市场的成长。此外,患者对成功诊断的尖端产品的认识不断增强也推动了成长。
由于感染疾病发病率上升、个人化医疗意识不断增强以及医疗保健系统的改善,预计亚太地区将在预测期内实现有益增长。亚洲国家的研究活动不断增加,特别是在基因组研究、肿瘤学和感染疾病研究领域。因此,PCR 作为一种准确、有效的 DNA 扩增方法已被广泛应用。此外,该地区多样化的人口和遗传变异需要强大的分子诊断来实现个体化治疗策略,这进一步推动了 PCR 市场的发展。
According to Stratistics MRC, the Global Polymerase Chain Reaction (PCR) Market is accounted for $8.9 billion in 2023 and is expected to reach $19.1 billion by 2030 growing at a CAGR of 11.5% during the forecast period. Polymerase Chain Reaction (PCR) is a molecular method for producing millions of copies of a particular DNA strand through in-vitro amplification. PCR is highly sensitive and can detect minute quantities of DNA. This is particularly advantageous in applications where the target DNA is present in low concentrations, such as in the early stages of certain diseases or when analyzing trace amounts of DNA in forensic samples.
According to Indian Council of Medical Research (ICMR), there will be a 12 percent rise in cancer cases in India by the 2027.
Rising demand for genetic testing
The rising demand for genetic testing has been a significant driver in the polymerase chain reaction (PCR) market. Genetic testing involves the analysis of an individual's DNA to identify genetic variations, mutations, and gene expression patterns. PCR plays a crucial role in this process by amplifying specific DNA sequences for further analysis. Additionally, genetic testing has gained popularity among individuals who are curious about their ancestry and want to explore their genetic heritage. Therefore, these advancements have expanded the applications of PCR in genetic testing, contributing to the growth of the PCR market.
High cost
The initial investment in PCR instruments, reagents, and consumables, coupled with the need for skilled personnel, contributes to the overall expense, especially for smaller diagnostic facilities and laboratories. The sophisticated nature of PCR equipment and the continuous requirement for quality control further add to the operational costs. Additionally, the expense of PCR tests may burden patients and healthcare systems, impacting the affordability and equitable distribution of cutting-edge diagnostic services. Therefore, high costs are a significant barrier to market expansion.
Technological advancements
Real-time PCR allows for the detection and quantification of PCR amplification in real-time, providing immediate results during the amplification process. This real-time monitoring enables faster and more precise analysis, making it valuable in fields such as clinical diagnostics, genetic testing, and research. Furthermore, advancements in PCR instrument technology have resulted in more user-friendly and automated systems. Integrated thermal cyclers with advanced temperature control algorithms and intuitive software interfaces have made PCR more accessible to a broader range of users, including researchers, clinicians, and technicians. These advancements in technology are a significant factor in accelerating market demand.
Complexity and technical expertise
A certain level of technical knowledge and training is required for the various steps involved in PCR techniques, which include primer design, reaction condition optimization, and data analysis. PCR protocols require careful design and selection of primers that specifically target the desired DNA regions. Designing primers with appropriate melting temperatures, avoiding secondary structures, and minimizing primer-dimer interactions can be challenging. The complexity and technical expertise required to perform polymerase chain reaction (PCR) act as restraints in the polymerase chain reaction (PCR) market.
The COVID-19 pandemic significantly impacted the polymerase chain reaction market growth. The growing demand in the clinical diagnostic market segment had a favourable effect on the PCR market. Healthcare professionals advised the population exhibiting COVID-19 symptoms to have a diagnostic test performed, and nearly all of these tests use RT-PCR since viral culture tests have not been recommended by the authorities. Most pharmaceutical and biotechnological companies were focusing on the research and development departments to identify new molecules or leads for the treatment of COVID-19.
The reagents segment is expected to be the largest during the forecast period
The reagents segment is estimated to hold the largest share. PCR reagents encompass a range of chemicals, including DNA polymerases, primers, nucleotides, and buffers, each playing a specific role in the reaction. DNA polymerases, such as Taq polymerase, catalyze the synthesis of complementary DNA strands, while primers provide the starting points for DNA amplification. Nucleotides serve as building blocks for the newly synthesized DNA strands, and buffers maintain the optimal pH conditions for enzymatic activity. The demand for high-quality and reliable reagents is paramount for the accuracy and efficiency of PCR reactions.
The diagnostic center segment is expected to have the highest CAGR during the forecast period
The diagnostic center segment is anticipated to have lucrative growth during the forecast period. PCR technology is extensively utilized in diagnostic centers for the detection of various diseases, including infectious agents, genetic disorders, and cancer. Diagnostic centers leverage PCR's high sensitivity and specificity to identify and quantify specific DNA or RNA sequences, aiding in the early and precise diagnosis of diseases. The versatility of PCR enables diagnostic centers to offer a wide range of tests, contributing to comprehensive patient care.
North America commanded the largest market share during the extrapolated period. The high frequency of diseases, the presence of important players in the region, the existence of favourable regulations, and a number of government initiatives pertaining to advancements in healthcare infrastructure all contribute to the growth of the regional market. An additional factor fueling the growth is growing patient awareness of the availability of contemporary products for successful diagnosis.
Asia Pacific is expected to witness profitable growth over the projection period, owing to the rising incidence of infectious diseases, the growing recognition of personalized medicine, and the improvements made to the healthcare system. Asian countries are seeing an increase in research endeavours, specifically in the fields of genomics, oncology, and infectious disease investigations. This has led to the widespread use of PCR as a precise and efficient method of amplifying DNA. Moreover, the region's diverse population and genetic variations necessitate robust molecular diagnostics for personalized treatment strategies, further fueling the PCR market.
Some of the key players in the Polymerase Chain Reaction (PCR) Market include Danaher Corporation, Fluidigm Corporation, Agilent Technologies, Inc., Stilla Technologies, Abbott, Cytiva, Microsynth AG, Qiagen, JN Medsys, Bio-Rad Laboratories, Inc., Thermo Fisher Scientific, Inc., F. Hoffmann-La Roche Ltd, Siemens, Johnson & Johnson Private Limited and Bruker.
In August 2022, Abbott and weightwatchers partner to support people living with diabetes in attaining their health goals. Two industry leaders join forces to empower people living with diabetes by providing information and insights to improve weight loss, glucose control and overall health.
In June 2021, Bio-Rad Laboratories, Inc., a global leader of life science research and clinical diagnostic products, announced a partnership with Seegene, Inc., a global leader in multiplex molecular diagnostics, for the clinical development and commercialization of infectious disease molecular diagnostic products.