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结构生物学和分子建模技术市场预测至 2030 年:按产品、工具、技术、应用和地区进行的全球分析Structural Biology & Molecular Modeling Market Forecasts to 2030 - Global Analysis By Product, Tools (Software as a Service & Standalone Modeling, Visualization & Analysis, Databases and Other Tools), Technology, Application and By Geography |
根据Stratistics MRC预测,2023年全球结构生物学和分子建模技术市场规模将达到49.1亿美元,预测期内复合年增长率为18.2%,预计到2030年将达到158.5亿美元。
结构生物学和分子建模技术是两个密切相关的领域,在分子层面上理解生物大分子的结构和功能方面发挥着重要作用。结构生物学和分子建模技术是多功能工具,可用于广泛的应用,从基础研究到医学、农业和工业的实际应用。在分子层面上理解生物过程有助于许多科学和技术领域的进步。
根据 2021 年 9 月发表在 MDPI日誌上的一篇研究论文,周边动脉疾病(PAD) 的盛行率估计在 3% 至 12% 之间,影响美国和欧洲约 2700 万人。
慢性疾病通常涉及复杂的分子途径。结构生物学透过提供详细资讯来帮助识别和检验潜在的药物研发标靶。结构生物学和分子建模技术有助于潜在药物研发标靶的识别和特异性治疗药物的设计。癌症和神经退化性疾病等慢性病的增加加速了对标靶治疗和个体化治疗的需求。
儘管取得了进步,我们对复杂生物系统的理解仍在不断发展中。对目标蛋白三维结构的有限了解阻碍了有效候选药物的识别和设计。结果,药物开发可能变得更慢、效率更低。此外,蛋白质-配体相互作用的预测准确性差和生物系统的复杂性等因素也阻碍了市场的成长。
人工智慧(AI)和机器学习(ML)在结构生物学和分子建模技术过程中的整合提高了资料分析的速度和准确性。人工智慧演算法可以分析生物资料来识别潜在的药物研发标靶,为开发更有效率的药物研发管道、提高治疗效果并最大限度地减少副作用提供机会。我们提供此次整合将进一步提高该领域药物研发发现和开发的效率、准确性和整体成功率。
结构生物学和分子建模技术通常需要昂贵的设备、软体和熟练人员。它在很大程度上依赖尖端技术和专业设备。建立和维护最先进的实验室和专业设施也需要大量的资本投资。此外,与分析实验资料相关的成本,例如软体许可证和解释技术人员,也会增加整体初期成本并阻碍市场需求。
生命科学领域的许多研究工作都针对与新冠病毒相关的研究,包括疫苗开发、药物再利用以及病毒结构和功能的阐明。这种资源的重新分配也影响了与新冠病毒无关的研究领域,例如结构生物学和分子建模。疫情期间的经济不确定性和优先事项的转变给研究计划的资金筹措带来了挑战。此外,寻找新冠病毒治疗方法的迫切需求增加了人们对抗病毒药物发现的兴趣和投资,间接使结构生物学和分子建模领域受益。
电子显微镜领域预计将出现良好的成长。电子显微镜技术提供高解析度,使研究人员能够在分子甚至原子层面上可视化结构。电子显微镜是结构生物学和分子建模的强大工具,可提供对于理解生物过程和疾病机制至关重要的详细结构资讯,并促进药物研发工作。电磁技术的不断进步正在增加其在该领域的重要性。
预计药物研发领域在预测期内将出现最高的复合年增长率。结构生物学和分子建模技术透过提供对疾病分子机制的宝贵见解并促进新疗法的设计,在药物研发中发挥重要作用。这些技术可以帮助简化药物研发流程,使其更有效率且更具成本效益。
由于投资的增加和研发的进步,预计亚太地区在预测期内将占据最大的市场占有率。亚太地区的製药和生物技术产业可能会对结构生物学和分子建模工具的需求做出重大贡献。此外,政府对科学研究和生物技术的措施和资助也可以对市场产生积极影响。
由于不断的进步、协作研究和伙伴关係,预计欧洲在预测期内将表现出最高的复合年增长率。政府资助、私人投资和津贴在促进该地区结构生物学和分子建模技术研究方面发挥着重要作用。欧洲市场的主要企业包括 Dassault Systemes、Agile Molecule 和 Acellera Limited。此外,资金筹措可用性和对个人化医疗日益增长的兴趣可能会影响欧洲市场的成长。
According to Stratistics MRC, the Global Structural Biology & Molecular Modeling Market is accounted for $4.91 billion in 2023 and is expected to reach $15.85 billion by 2030 growing at a CAGR of 18.2% during the forecast period. Structural Biology and Molecular Modeling are two closely related fields that play a crucial role in understanding the structure and function of biological macromolecules at the molecular level. They are versatile tools with applications ranging from basic research to practical applications in medicine, agriculture, and industry. They provide a molecular-level understanding of biological processes, facilitating advancements in various scientific and technological fields.
According to the MDPI Journal research article published in September 2021, the prevalence of Peripheral Arterial Disease (PAD) is estimated to be 3-12%, affecting nearly 27 million people in America and Europe.
Chronic diseases often involve complex molecular pathways. Structural biology helps identify and validate potential drug targets by providing detailed information. Structural biology and molecular modeling contribute to the identification of potential drug targets and the design of specific therapeutics. The increasing prevalence of chronic diseases, such as cancer and neurodegenerative disorders, has fuelled the demand for targeted and personalized therapies.
Despite advancements, understanding of complex biological systems is still evolving. A limited understanding of the three-dimensional structures of target proteins can impede the identification and design of effective drug candidates. This can result in a slower and less efficient drug development process. Additionally, factors such as inaccuracy in predicting protein-ligand interactions and complexities of biological systems hampers the market growth.
The integration of artificial intelligence (AI) and machine learning (ML) in structural biology and molecular modeling processes enhances the speed and accuracy of data analysis. AI algorithms can analyze biological data to identify potential drug targets. It presents opportunities for the development of more efficient drug discovery pipelines, improving treatment efficacy and minimizing side effects. This integration further enhances the efficiency, accuracy, and overall success rate of drug discovery and development efforts in this field.
Structural biology and molecular modeling techniques often involve expensive equipment, software, and skilled personnel. They heavily rely on cutting-edge technologies and specialized equipment. Also, establishing & maintaining state-of-the-art laboratories and specialized facilities requires significant capital investment. Additionally, the costs associated with analyzing experimental data, including software licenses and skilled personnel for interpretation contribute to the overall initial expenses thereby hampering the market demand.
Many research efforts in the life sciences were redirected toward covid related studies, including vaccine development, drug repurposing, and understanding the virus's structure and function. This redirection of resources has impacted non-covid-related research areas, including structural biology and molecular modeling. Economic uncertainties and shifting priorities during the pandemic have led to funding challenges for research projects. Further, the urgency of finding treatments for covid has spurred increased interest and investment in antiviral drug discovery, which indirectly benefitted the structural biology and molecular modeling sector.
The electron microscopy segment is estimated to have a lucrative growth. Electron microscopy technique offers high resolution and allows researchers to visualize structures at the molecular and even atomic levels. It is a powerful tool in structural biology and molecular modeling, providing detailed structural information that is crucial for understanding biological processes, disease mechanisms, and facilitating drug discovery efforts. The continuous advancements in EM technology further contribute to its significance in the field.
The drug discovery segment is anticipated to witness the highest CAGR growth during the forecast period. Structural biology and molecular modeling play crucial roles in drug discovery by providing valuable insights into the molecular mechanisms of diseases and facilitating the design of novel therapeutic agents. These techniques help streamline the drug discovery pipeline, making it more efficient and cost-effective.
Asia Pacific is projected to hold the largest market share during the forecast period owing to the increasing investments and advances in research and development. The pharmaceutical and biotechnology industries in the Asia Pacific region are likely to contribute significantly to the demand for structural biology and molecular modeling tools. Further, government initiatives and funding for scientific research and biotechnology can positively influence the market.
Europe is projected to have the highest CAGR over the forecast period, owing to the continuous advancements, collaborations and partnerships. Government funding, private investments and grants play a significant role in advancing research in structural biology and molecular modeling in the region. Some prominent players in the European market include Dassault Systemes, Agile Molecule and Acellera Limited. Further, funding availability and growing emphasis on personalized medicine can impact the growth of the market in europe.
Some of the key players profiled in the Structural Biology & Molecular Modeling Market include Acellera Limited, Thermo Fisher Scientific Inc, Illumina Inc., Horiba, Chemical Computing Group ULC, Bruker Daltonics, Agilent Technologies Inc., Charles River Laboratories, Dassault Systemes, Biomax Informatics AG, Agile Molecule and Bioinformatic LLC.
In November 2023, The Accelra Company released a new version of ACEMD, Accela's molecular dynamics simulation software. ACEMD is a highly optimized molecular dynamics (MD) engine that runs on NVIDIA GPUs. It's free for non-profit research, but commercial licenses are available for other uses.
In September 2023, Thermo Scientific launched the new Hydra Bio Plasma-Focused Ion Beam (Plasma-FIB) for cell biologists seeking simplified workflows while undertaking volume electron microscopy for cryo or resin-embedded samples. The Hydra Bio Plasma-FIB is a versatile, multi-application instrument that supports volume electron microscopy and sample preparation for the cryo-electron tomography workflow.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.