市场调查报告书
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1403420
2030 年短肠症候群市场预测:按诊断、治疗方法、药物类别、配销通路和地区进行的全球分析Short Bowel Syndrome Market Forecasts to 2030 - Global Analysis By Diagnosis (Blood Tests, Imaging Procedures, Physical Exam and Other Diagnoses),Treatment, Drug Class, Distribution Channel and By Geography |
根据 Stratistics MRC 的数据,2023 年全球短肠症候群市场规模为 18 亿美元,预计在预测期内复合年增长率为 17.9%,到 2030 年将达到 57 亿美元。
小肠或大肠的某些部分可能会消失或停止功能,导致一种称为短肠症候群的复杂疾病。因此,小肠症候群患者经常出现吸收不良,即脂肪、碳水化合物(糖)、维生素、矿物质、微量元素和水等营养素的吸收减少。缺乏重要的维生素和矿物质可能会导致营养不良、体重意外减轻和其他症状。
根据 WebMD LLC 2021 年发布的资料,每人每年的肠外支持费用约为 65,000 美元至 320,000 美元。
患有这种疾病的患者越来越需要静脉补液以维持正常的尿流量和水合水平。由于这些患者面临的挑战,业内许多知名公司正在努力满足这项需求。由于髂骨的缺陷会导致镁吸收不良并导致低镁血症,因此许多公司开发了镁补充品来帮助患者保持充足的水分。
市场面临的主要障碍是用于治疗短肠症候群的药物的副作用。 Revestive 和 Gatex 最典型的健康副作用包括头痛、噁心、呕吐、感冒和流感。此外,这些药物已被证明能够引起其他健康问题,如大肠息肉、胆囊发炎、胰臟阻塞、可能变成癌症的细胞异常发育和肠阻塞。
近年来,短肠症候群变得越来越常见。给药全肠外营养的患者数量正在增加,这推动了市场的扩张。短肠症候群的发生率估计为每 100 万人 4 例,但实际发生率接近每 100 万人 3 例。接受肠外营养的大量患者预测了这种疾病的确切盛行率,但这尚不清楚。
肠外营养是治疗方法这种疾病最受欢迎的方法,但价格昂贵。肠外营养治疗可以在医院或家中进行。另一方面,在家接受肠外营养的患者的治疗费用低于在医院接受肠外营养的患者。此外,用于治疗这种疾病的药物每年的高昂费用进一步限制了商业性接受度。
由于这项发现,短肠症候群市场的製造商正在扩大其收入前景,因为 COVID-19 患者报告出现胃肠道问题。另一方面,SBS治疗需要长期肠外营养或器官移植。因此,企业和学术界应该共同努力,进一步发展自组织工程研究领域,以实现利用患者自身细胞和组织进行治疗。公司正在增加生长激素、低动力药物和抗胰泌素药物的产量。
预计谷氨酰胺细分市场在预测期内将达到最高水准。一种称为麸酰胺酸的胺基酸是肠道细胞的主要能源来源。麸酰胺酸支持肠道屏障功能,有助于维持肠道黏膜完整性,也可能降低肠道渗透性。它可以透过促进肠道组织修復和缩短肠道手术后的恢復期来促进癒合。
预计药物治疗领域在预测期内复合年增长率最高。药物可以帮助缓解与这种疾病相关的常见症状,例如腹胀、腹泻、胃部不适和营养不良。某些药物可以透过改善营养物质和电解质的吸收来补偿肠道功能表面积的损失。这有助于防止营养不良及其后果。
由于久坐生活方式的增加、医疗基础设施的改善以及政府对克隆氏症研究的资助增加,预计北美将在预测期内占据最大的市场占有率。近年来,由于久坐生活方式的发展,短肠症候群的使用显着增加,导致专注于健康用餐,垃圾食物增加。因此,肠病市场持续成长。
预计亚太地区在预测期内复合年增长率最高。该地区正经历大公司的直接存在、对新疗法市场开拓的大量研发投资以及对基于 GLP-2 的疗法的临床试验的日益重视,这些因素正在推动市场成长。推动市场扩张的主要原因是短肠症候群患者数量的显着增加(尤其是在新兴国家)、快速都市化以及政府在医疗基础设施方面的支出增加。
According to Stratistics MRC, the Global Short Bowel Syndrome Market is accounted for $1.8 billion in 2023 and is expected to reach $5.7 billion by 2030 growing at a CAGR of 17.9% during the forecast period. A part of the small or large intestine may physically disappear or cease to function, resulting in the complicated condition known as short bowel syndrome. As a result, malabsorption-the decreased absorption of nutrients such as lipids, carbohydrates (sugars), vitamins, minerals, trace elements, and fluids-occurs often in people with small bowel syndrome. Malnutrition, inadvertent weight loss, and other symptoms might result from the deficiency of vital vitamins and minerals.
According to the data published by WebMD LLC in 2021, the cost of parenteral support per person is around USD 65,000 to USD 320,000 annually.
Patients with this disease are increasingly requiring intravenous fluid supplementation to maintain normal urine flow and hydration levels. Given that these individuals have difficulties, a number of prominent firms in the industry are attempting to address this need. Since the loss of the distal ileum results in malabsorption of magnesium, which causes hypomagnesemia, a number of firms are creating magnesium supplements to aid patients in getting enough water.
The main obstacle facing the market is the adverse effects of medications used to treat short bowel syndrome. The most typical side effects of Revestive or Gattex on health include headaches, nausea, vomiting, colds, and flu. Furthermore, it has been shown that these medications may result in other health issues such colon polyps, gallbladder inflammation, pancreatic obstruction, aberrant cell development that may result in cancer, and intestinal blockage.
Short bowel syndrome has become more common in recent years. The number of patients receiving complete parenteral nutrition is growing, which has fueled market expansion. The estimated incidence of short bowel syndrome is four cases per million, although actual incidence is closer to three cases per million. Given the amount of patients receiving parenteral nourishment, the disease's precise prevalence is predicted, despite the lack of clarity in this regard.
The most popular therapy for treating this illness is parenteral feeding, which comes with a high expense for the entire course of care. Both in-hospital and at-home environments can perform this treatment. On the other hand, compared to patients getting parenteral nourishment in hospitals, the cost of care for those receiving it at home is lower. Furthermore, the prohibitive yearly expense of the medications used to treat this illness further restricts their commercial acceptance.
Manufacturers in the short bowel syndrome market are expanding their income prospects as a result of the results, since individuals with COVID-19 have reported experiencing gastrointestinal issues. On the other hand, long-term parenteral feeding or an organ transplant are necessary for the SBS therapy. Thus, businesses and academics ought to work together to further the field of autologous tissue engineering research, which enables patients to be treated with their own cells or tissues. Businesses are increasing their production of growth hormones, hypomotility drugs and anti-secretin medicines.
The glutamine segment is expected to be the largest during the forecast period. An amino acid called glutamine is the main energy source for the intestinal lining cells. It supports the operation of the gut barrier, aids in preserving the integrity of the intestinal mucosa, and may even lessen intestinal permeability. By encouraging the repair of the intestinal tissues and shortening the recovery period following intestinal surgery, it may facilitate recuperation.
The medications segment is expected to have the highest CAGR during the forecast period. Drugs can aid in the relief of symptoms including bloating, diarrhea, stomach discomfort, and nutritional deficits that are frequently linked to this illness. Certain drugs can make up for the decreased functional surface area of the gut by improving the absorption of nutrients and electrolytes. This aids in the prevention of malnutrition and its consequences.
North America is projected to hold the largest market share during the forecast period due to the increased sedentary lifestyle, increased healthcare infrastructure, and rising funding from the government on the research of Crohn's disease, among others. The use of short bowel syndrome has expanded significantly in recent years due to the development in sedentary lifestyles, which have left people with less time to focus on eating wholesome foods and more junk food. As a result, the market for intestinal diseases has continued to grow.
Asia Pacific is projected to hold the highest CAGR over the forecast period. The market is growing in this area due to the direct presence of large companies, significant R&D investments in the development of novel medications, and an increasing emphasis on clinical trials for GLP-2-based therapies. The primary reasons propelling the market expansion are the notable increase in short bowel syndrome cases, especially in emerging nations, rapid urbanization, and rising government spending on healthcare infrastructure.
Some of the key players in Short Bowel Syndrome market include VectivBio AG, Takeda Pharmaceutical Company Limited, Nutrinia, Merck KGaA, Ardelyx, OxThera Inc, Zealand Pharma, Nestle Health Science, Hanmi Pharm.Co., Ltd, Sancilio&Company Inc, Meters Biopharma and OPKO Health, Inc.
In September 2022, Zealand Pharma A/S announced positive results from a phase 3 trial of Glepaglutide for treatment of short bowel syndrome. Glepaglutide is the potential best-in-class long-acting GLP-2 analog. The candidate has distinct advantages over Teduglutide, including once-weekly dosing and a longer half-life.
In March 2022, VectivBio AG announced a licensing agreement with Asahi Kasei Pharma Corporation to commercialize and develop apraglutide in Japan, which is used to treat SBS.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.