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市场调查报告书
商品编码
1403426
迟发性治疗药物到2030年的全球市场预测:依产品类型、疾病类型、给药途径、配销通路和地区进行分析Tardive Dyskinesia Therapeutics Market Forecasts to 2030 - Global Analysis By Product Type, Disease Type, Route Of Administration, Distribution Channel and By Geography |
根据 Stratistics MRC 的数据,2023 年全球迟发性药物市场规模将达到 25 亿美元,预计 2030 年将达到 54 亿美元,预测期内复合年增长率为 11.1%。
药物引起的运动疾病称为迟发性(TD),会导致舌头、脸部、躯干和四肢不受控制地运动。迟发性是长期使用某些精神药物(如抗精神病药物)的副作用。儘管有时也会影响其他患者,但这种疾病最常见于长期服用抗精神病药物的精神分裂症、分裂情感性疾患和躁郁症患者。
根据 John Wiley &Sons, Inc. 于 2022 年 8 月发表的一篇论文,在欧洲接受抗精神病药物治疗的精神病患者中,迟发性的盛行率为 23.3%。
迟发性盛行率上升
提高认识可能有助于早期发现和治疗,减轻症状的严重。研究的进步将导致更专业的药物和治疗方法的开发,为受影响的人提供更个性化的护理。此外,提高意识将鼓励为进一步研究提供资金筹措,激发创造力,发现治疗和预防迟发性的新方法,并最终减少受这种疾病影响的人数,提高人们的生活品质。
复杂的管理
迟发性的治疗通常涉及多种策略的组合,包括改变目前的治疗方案或添加新的治疗方案。这种复杂性可能会使治疗变得困难,尤其是在兼顾控制原始药物所治疗的潜在疾病的需要时。用于控制它的治疗方法可能会产生轻微到严重的副作用,可能需要密切监测和管理。
改善识别和诊断
早期发现可以及时治疗,减缓病程并改善患者的治疗效果。更多知识使医疗保健专业人员能够积极监测患者,从而更容易快速改变处方时间表或使用其他治疗方法来控制症状。此外,增加知识有助于患者教育和支持、减少耻辱并促进富有同情心的医疗保健方法。这样的综合策略最终将改善人们的生活品质并促进市场扩张。
製药公司研发投入限制
治疗罕见疾病药物研发的主要挑战之一是能够参与临床试验的患者数量较少。只有几百、几千名罕见疾病患者有资格参加临床试验。罕见疾病患者数量非常少。此外,研究费用昂贵且投资回报不明,这可能导致製药公司不愿为其提供资金。
这场大流行扰乱了全球医疗保健服务,影响了常规检查、专家咨询以及面对面治疗的可用性。结果,许多迟发性患者的治疗被推迟或中断。 COVID-19 影响了正在进行的与迟发性相关的临床试验和研究的进展。由于探视限製或入组挑战,一些临床试验可能会被推迟或修改。
预计在预测期内,丁苯那嗪部分将是最大的
预计Deutetrabenazine细分市场在预测期内将是最大的细分市场。氘替代延长了半衰期,提高了疗效和安全性,减少了与给药相关的副作用,并提高了患者的医嘱遵从性。这种化合物有望抑制与迟发性相关的不自主运动,从而提供更一致且更易于管理的治疗方法。
迟发性肌张力不全症地区预计在预测期内复合年增长率最高
迟发性肌张力不全症领域预计在预测期内复合年增长率最高。迟发性肌张力不全症是迟发性的一种亚型,具体涉及持续的肌肉收缩,导致重复的扭转运动和异常姿势。调整或停用引发迟发性肌张力不全症的药物可能会改善或消除症状。然而,这种情况必须由医疗专业人员仔细处理,平衡药物的益处与精神状态恶化的风险。
预计北美在预测期内将占据最大的市场占有率。多家製药公司正在投资开发专门用于症状管理的药物。这些治疗旨在透过减轻与疾病相关的不自主运动来改善受影响个体的生活品质。随着治疗方法选择的进步以及医疗保健提供者对这些治疗方法的接受程度不断提高,市场正在呈现成长。
由于医疗保健意识的提高、诊断技术的改进和高龄化,预计亚太地区在预测期内将保持最高的复合年增长率。製药公司正在努力开发针对症状的新治疗方法和药物,以解决该领域未满足的医疗需求。国内和全球製药公司之间的合作以及诊断和治疗技术的进步也有助于该地区的市场扩张。
According to Stratistics MRC, the Global Tardive Dyskinesia Therapeutics Market is accounted for $2.5 billion in 2023 and is expected to reach $5.4 billion by 2030 growing at a CAGR of 11.1% during the forecast period. A drug-induced movement condition called tardive dyskinesia (TD) results in uncontrollably moving the tongue, face, torso, and limbs. It is a side effect brought on by extended use of specific psychiatric drug classes, such antipsychotics. Although they sometimes afflict other patients as well, the illness is most frequent among those who have been taken long-term antipsychotic drugs for schizophrenia, schizoaffective disorder, or bipolar disorder.
According to an article published by John Wiley & Sons, Inc., in August 2022, the prevalence of tardive dyskinesia in Europe is 23.3% amongst psychiatric patients receiving treatment with antipsychotics.
Increased consciousness encourages early identification and action, which may lessen the severity of symptoms. Research progresses lead to the creation of more specialized drugs and therapies, providing impacted people with more individualized care. Furthermore, greater awareness encourages financing for additional research, which spurs creativity and reveals fresh approaches to tardive dyskinesia therapy and prevention, eventually enhancing the quality of life for individuals affected by the disorder.
The management of tardive dyskinesia frequently entails a mix of strategies, such as changing current prescriptions or adding new ones. This intricacy can make treatment difficult, particularly when juggling the requirement to manage the underlying condition for which the original medication was prescribed. Therapeutic options for management have a range of side effects, from mild to severe, which may require close monitoring and management.
Early detection enables timely management, which may slow its course and enhance patient outcomes. Increased knowledge encourages healthcare professionals to monitor patients proactively, which makes it easier to control symptoms by promptly changing prescription schedules or using other therapies. Moreover, better knowledge promotes patient education and support, lessens stigma, and encourages a more compassionate approach to healthcare. This all-encompassing strategy eventually improves people's quality of life, which fuels market expansion.
One of the major challenges of rare disease drugs in terms of research and development is the small patient population available for clinical trials. Only a few hundred or few thousand patients with rare diseases are accessible for clinical trials. Rare diseases afflict a tiny population. Furthermore, because research may be expensive and have hazy returns on investment, pharmaceutical corporations could be reluctant to fund it.
The pandemic caused disruptions in healthcare services globally, affecting regular check-ups, access to specialists, and availability of in-person treatments. This led to delays or interruptions in treatment for many individuals with tardive dyskinesia. COVID-19 impacted the progress of ongoing clinical trials and research studies related to tardive dyskinesia. Some trials might have been delayed or modified due to restrictions on in-person visits and enrollment challenges.
The deutetrabenazine segment is expected to be the largest during the forecast period. Its deuterium substitution enhances its efficacy and safety profile by prolonging its half-life, leading to fewer dose-related side effects and improved patient adherence. This compound demonstrates potential in reducing involuntary movements associated with Tardive Dyskinesia while offering a more consistent and manageable treatment approach.
The tardive dystonia segment is expected to have the highest CAGR during the forecast period. Tardive dystonia, a subtype of tardive dyskinesia, specifically involves sustained muscle contractions causing repetitive, twisting movements or abnormal postures. Sometimes, adjusting or discontinuing the medications that trigger tardive dystonia can lead to improvement or resolution of symptoms. However, this must be carefully managed by a healthcare professional to balance the benefits of the medication with the risk of worsening psychiatric conditions.
North America is projected to hold the largest market share during the forecast period. Several pharmaceutical companies have been investing in developing medications specifically targeted to manage symptoms. These treatments aim to alleviate the involuntary movements associated with the condition, thereby improving the quality of life for affected individuals. The market has shown growth in terms of advancements in therapeutic options and the growing acceptance of these treatments among healthcare providers.
Asia Pacific is projected to hold the highest CAGR over the forecast period due to rising healthcare awareness, improving diagnostic techniques, and an aging population. Pharmaceutical companies were working on developing new treatments and medications targeting symptoms, aiming to address the unmet medical needs in this area. Collaborations between local and global pharmaceutical companies, as well as advancements in technology for diagnosis and treatment, were also contributing to the expansion of the market in the region.
Some of the key players in Tardive Dyskinesia Therapeutics market include Mitsubishi Tanabe Pharma Corporation, Luye Pharma Group, Teva Pharmaceutical Industries Ltd., Neurocrine Biosciences, Inc., SOM BIOTECH, Sun Pharmaceutical Industries Ltd, AbbVie Inc , Sanis, SteriMax Inc., Adamas Pharmaceuticals, Inc , Reddys Laboratories Ltd, Mylan N.V., Bausch Health, Johnson & Johnson Services, Lupin Pharmaceuticals Inc, Novartis AG, Baxter, Amgen Inc, Pfizer Inc and Medicure Inc.
In February 2023, Teva Pharmaceuticals announced the print publication of the IMPACT-TD Scale, an easy-to-use, standardized and clinician-rated assessment. The scale, developed by a consensus panel, will assist healthcare providers in determining the impact of tardive dyskinesia (TD) on different aspects of a patient's daily functioning.
In December 2021, Mitsubishi Tanabe Pharma Corporation and Janssen Pharmaceutical K.K. have entered into a co-promotion agreement for MT-5199, a vesicular monoamine transporter type 2 (VMAT2) inhibitor, which is intended for use as tardive dyskinesia therapeutics in Japan.