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市场调查报告书
商品编码
1403461
2030 年微生物组定序服务市场预测:按类型、服务、技术、应用、最终用户和地区进行的全球分析Microbiome Sequencing Services Market Forecasts to 2030 - Global Analysis By Type, Service, Technology, Application, End User and By Geography |
根据 Stratistics MRC 的数据,2023 年全球微生物组定序服务市场规模将达到 15.4 亿美元,预计到 2030 年将达到 36.1 亿美元,预测期内复合年增长率为 12.9%。
微生物组定序服务分析样本中微生物的 DNA,揭示生活在特定环境(例如人类肠道)中的不同微生物群落的详细资讯。这对于推进个人化医疗、疾病诊断以及理解微生物组与各种生态系统之间复杂的相互作用至关重要。这些服务可识别和量化微生物种类,并帮助研究人员和临床医生了解微生物组的组成和功能。
澳洲癌症协会2022年资料更新估计,2022年澳洲将新诊断出162,163例癌症病例,其中男性88,982例,女性73,181例。
生物製药公司越来越认识到微生物组在人类健康和疾病中发挥的关键作用,为标靶治疗和精准医疗方法的发展铺平了道路。生物製药公司正在利用微生物组定序进行临床前和临床试验,以了解治疗治疗性介入对微生物生态系统的影响。此外,对肠道微生物组的探索尤其因其调节药物代谢、功效和安全性的潜力而受到关注,从而推动了该市场的规模。
小型研究机构、学术实验室和新兴企业面临独特的财务挑战,由于成本高昂,他们无法彻底实施微生物组定序服务。这些高成本加剧了研究人员和组织的经济障碍,包括样本采集、DNA 提取、文库製备和资料分析。此外,微生物组分析的复杂性需要先进的定序技术和生物资讯学知识,增加了这些服务的整体高成本,阻碍了该市场的规模。
技术的进步使研究人员能够产生大量资料,有助于更全面地了解不同生态系统中的微生物群落。次世代定序仪(NGS)平台、Illumina和Thermo Fisher等技术大大增加了微生物组定序的深度和广度。此外,提高的定序准确性、更长的读长和增加的通量有助于识别和表征更广泛的微生物物种,从而推动该市场的扩张。
不同平台和服务供应商之间的协议、方法和资料分析程序缺乏统一性,为比较和解释结果带来了挑战。这种变异性可能导致微生物群落分析的不一致。此外,缺乏样本采集、DNA 萃取和定序文库製备的标准化方法可能会对微生物组资料造成偏差和错误。这不仅影响学术研究,也影响微生物组定序向临床应用和法律规范的过渡,阻碍市场成长。
COVID-19 的爆发以多种方式对微生物组定序服务市场产生了负面影响。供应链中断、物流挑战和实验室活动限制阻碍了微生物组定序服务的无缝运作。许多研究机构和生技公司面临财务困难,进一步限制了微生物组研究和定序服务的投资。此外,临床试验和学术研究活动减少了学术和工业环境中对微生物组定序服务的需求,阻碍了该市场的成长。
全基因组定序领域预计将在估计和预测期间占据最大份额,因为它能够获得广泛的遗传资讯,从而能够检测微生物群落内的稀有物种和变异。此外,该技术还能对生物体的整个 DNA 进行定序,从而可以详细了解其基因组成、功能元件和潜在的毒力因子。该技术有助于加速发现并指导治疗性介入,从而推动该领域的成长。
连接定序(SBL)领域预计在预测期内复合年增长率最高。在 SBL 中,DNA 片段使用特定的接头连接形成串联结构。这提供了诸如高精度、长读长以及从困难的基因组区域检索资讯的能力等优点。此外,研究人员和服务供应商可以全面了解微生物基因组,帮助了解群落动态、功能潜力和宿主-微生物组相互作用。
人们越来越认识到微生物组对健康和疾病的影响,再加上精准医疗和个体化医疗保健的重要性日益增加,在估计期间占据了最大的市场占有率。中国、日本、韩国和印度等国家正在促进研究机构、生技公司和定序服务供应商之间的合作。此外,随着研究能力和基础设施的不断加强,高通量定序技术和生物资讯能力的进步进一步推动了该地区的成长。
预计欧洲在预测期内的复合年增长率最高。欧洲各地的多样化人口为微生物组研究提供了丰富的环境,使研究人员能够研究微生物组成的变化及其对区域健康模式的影响。此外,Illumina, Inc.、Macrogen, Inc.、Genewiz 和 Eurofins Scientific 等主要企业为个人化医疗、农业实践和对微生物生态系统的了解做出了重大贡献,正在推动该地区的扩张。我是。
According to Stratistics MRC, the Global Microbiome Sequencing Services Market is accounted for $1.54 billion in 2023 and is expected to reach $3.61 billion by 2030 growing at a CAGR of 12.9% during the forecast period. Microbiome sequencing services analyze the DNA of microorganisms in a sample to reveal details about the diverse community of microbes living in a particular environment, like the human gut. It is crucial for personalized medicine, disease diagnostics, and advancing our understanding of the intricate interplay between microbiota and various ecosystems. These services identify and quantify microbial species, helping researchers and clinicians understand the microbiome's composition and function.
According to the data updated by Cancer Australia in 2022, it was estimated that 162,163 new cases of cancer would be diagnosed in Australia in 2022, out of which 88,982 would be males and 73,181 females.
Biopharmaceutical companies are increasingly recognizing the pivotal role of the microbiome in influencing human health and disease, paving the way for the development of targeted therapies and precision medicine approaches. Biopharmaceutical companies leverage microbiome sequencing to conduct preclinical and clinical trials, aiming to understand the impact of therapeutic interventions on microbial ecosystems. Furthermore, the exploration of the gut microbiome, in particular, has garnered attention for its potential in modulating drug metabolism, efficacy, and safety, which is boosting this market size.
Smaller research institutions, academic laboratories, and startups face unique financial challenges that prevent their capacity to conduct thorough microbiome sequencing services due to high costs. Financial obstacles for researchers and organizations are made worse by these high costs, which include sample collection, DNA extraction, library preparation, and data analysis. Additionally, the complexity of microbiome analysis, which necessitates sophisticated sequencing technologies and bioinformatics knowledge, adds to the overall high cost of these services, which is hindering this market size.
The technological strides enable researchers to generate vast amounts of data, facilitating a more comprehensive understanding of microbial communities within diverse ecosystems. Technologies such as next-generation sequencing (NGS) platforms, Illumina's, and Thermo Fisher's offerings have significantly enhanced the depth and breadth of microbiome sequencing. Furthermore, improved sequencing accuracy, longer read lengths, and increased throughput contribute to the identification and characterization of a wider range of microbial species, thereby propelling this market expansion.
The lack of uniformity in protocols, methodologies, and data analysis procedures across different platforms and service providers introduces challenges in comparing and interpreting results. This variability can lead to inconsistencies in microbial community profiling. Furthermore, the absence of standardized practices in sample collection, DNA extraction, and sequencing library preparation can contribute to biases and errors in microbiome data. This not only affects academic research but also impacts the translation of microbiome sequencing into clinical applications and regulatory frameworks, hindering the market's growth.
The COVID-19 pandemic has negatively impacted the microbiome sequencing services market in various ways. Disruptions in supply chains, logistical challenges, and restrictions on laboratory activities have impeded the seamless operation of microbiome sequencing services. Many research institutions and biotechnology companies faced financial constraints, further limiting investments in microbiome studies and sequencing services. Additionally, clinical trials and academic research activities decreased demand for microbiome sequencing services in both academic and industrial settings, impeding this market's growth.
The whole-genome sequencing segment is estimated to hold the largest share during the forecast period, due to its ability to capture a broad spectrum of genetic information, enabling the detection of rare species and variations within microbial communities. Additionally, this technique involves sequencing the entire DNA of an organism, providing a detailed understanding of its genetic makeup, functional elements, and potential virulence factors. It is instrumental in fueling discoveries and guiding therapeutic interventions, thereby driving this segment's growth.
The sequencing by ligation (SBL) segment is anticipated to have highest CAGR during the forecast period. In SBL, DNA fragments are ligated together using specific adapters, forming a concatemeric structure. This offers advantages such as high accuracy, long read lengths, and the ability to capture information from challenging genomic regions. In addition, researchers and service providers obtain comprehensive insights into microbial genomes, aiding in the understanding of community dynamics, functional potential, and host-microbiome interactions, which are boosting this market expansion.
Asia Pacific commanded the largest market share during the extrapolated period owing to increasing awareness of the microbiome's impact on health and disease, coupled with a rising emphasis on precision medicine and personalized healthcare. Countries like China, Japan, South Korea, and India foster collaborations between research institutions, biotechnology companies, and sequencing service providers. In addition, as research capabilities and infrastructure continue to strengthen the advancements in high-throughput sequencing technologies and bioinformatics capabilities further propel the region's growth.
Europe is expected to witness highest CAGR over the projection period. The diverse population across Europe provides a rich landscape for microbiome studies, enabling researchers to explore variations in microbial compositions and their impact on regional health patterns. Key players such as Illumina, Inc., Macrogen, Inc., Genewiz, and Eurofins Scientific also contribute significantly to advancements in personalized medicine, agricultural practices, and our understanding of microbial ecosystems, thus driving this region's expansion.
Some of the key players in the Microbiome Sequencing Services Market include DNA Genotek Inc., Thermo Fisher Scientific Inc., Illumina, Inc., Metabiomics, CosmosID, Zymo Research, Corporation, PerkinElmer, Inc., BGI Genomics Co., Ltd., Rancho Biosciences, Baseclear BV, Diversigen, Inc., Merieux Nutrisciences Corporations, Clinical Microbiomics AS, Bio-Rad Laboratories, Inc. and Genewiz Inc.
In November 2023, Illumina Inc., a global leader in DNA sequencing and array-based technologies announced the launch of the Global Health Access Initiative to support access to pathogen sequencing tools for public health in low- and middle-income countries (LMICs).
In October 2023, Thermo Fisher Scientific, the world leader in serving science, has introduced the Thermo Scientific™ Meridian™ EX System- an electron-beam-based failure analysis solution designed to enable precise fault localization on advanced semiconductor logic technologies.
In July 2023, Bio-Rad Laboratories, Inc. announced that the companies have agreed to settle their patent dispute pending in the U.S. District Court of Delaware pursuant to a global settlement and patent cross-licensing agreement relating to digital PCR technology.