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市场调查报告书
商品编码
1403510
2030 年人类血小板裂解物市场预测:按药物类型、给药途径、配销通路、最终用户和地区进行的全球分析Human Platelet Lysate Market Forecasts to 2030 - Global Analysis By Drug Type, Route of Administration, Distribution Channel, End User and By Geography |
根据 Stratistics MRC 的数据,2023 年全球人血小板裂解物市场规模为 5,375 万美元,预计到 2030 年将达到 8,029 万美元,预测期内复合年增长率为 5.9%。
人类血小板裂解物 (HPL) 是一种源自人类血小板的细胞培养补充品。含有血小板衍生生长因子(PDGF)、转化生长因子β(TGF-B)和类胰岛素生长因子(IGF)等生长因子,以及促进细胞存活和刺激组织再生的各种蛋白质。此外,与牛(FBS) 等传统细胞培养补充品相比,它具有许多优势。 HPL 需求不断增长是由于多种驱动因素,包括其安全性、效率和道德考虑。
美国国家医学图书馆发布的资料表明,人类血小板裂解物 (hPL) 的製造成本比牛更昂贵,而胎牛血清是人类血小板裂解物 (hPL) 的替代选择。
人类血小板裂解物因富含细胞生长和增殖所必需的生长因子和细胞激素而闻名,已成为传统血清培养基的绝佳替代品。它支持细胞增殖、维持细胞特性和促进组织再生的能力使其在再生医学、干细胞研究和组织工程中越来越多的采用。此外,对个人化医疗、基于细胞的治疗方法的日益关注以及基于细胞培养的药物研发发现的进步进一步增加了对人类血小板裂解物的需求。因此,将促进市场的成长。
人类血小板裂解物经历了复杂的製造过程,包括收集、处理和品管,导致与传统的基于血清的培养基相比,製造成本更高。如此高的成本限制了细胞培养应用中广泛商业性用途的承受能力和可用性,并可能阻碍其采用。结果,市场扩张受到阻碍。
人类血小板裂解物富含细胞增生和组织再生必需的生长因子和细胞激素,完美满足再生治疗的要求。随着再生医学的不断发展,HPL 已成为细胞培养中的重要辅助剂,可支持细胞增殖并维持组织再生所需的细胞特性。此外,其促进创伤治疗、刺激组织修復和帮助开发基于细胞的治疗方法的能力使人类血小板裂解物成为再生医学应用中的宝贵成分。
儘管与牛(FBS) 相比,异种污染减少,但人类血小板裂解物具有人源产品传播病原体的潜在风险。细菌和病毒等污染物可能会损害人类血小板裂解物的品质和安全性,影响其在研究和临床环境中细胞培养应用的适用性。因此,这是市场拓展的主要障碍。
COVID-19 大流行最初造成了医疗保健行业的混乱和捐血限制,影响了 HPL 製造的原材料的可得性。供应链中断和实验室活动减少扰乱了 HPL 的製造和分销。然而,这场大流行凸显了基于细胞的疗法的重要性,并增加了人们对 HPL 发挥关键作用的再生医学和细胞培养应用的兴趣。随着医疗保健产业的适应,随着细胞治疗方法研究重点的增加,市场已经捲土重来,这可能会进一步推动对 HPL 的需求。
据估计,基于肝素的人类血小板裂解物部分占最大份额。肝素用于防止血小板采集和 HPL 製造过程中发生凝血,确保维持血小板完整性和生物活性。这种专门的 HPL 透过支持细胞生长、增殖和活力,为细胞培养应用带来好处。肝素配方可增强 HPL 功能,特别有益于各种生物医学领域,例如再生医学、干细胞研究和组织工程,在这些领域中,维持血小板生物活性对于获得最佳细胞培养结果至关重要。
预计医院药局业务在预测期内将出现良好成长。医院药局是向医疗机构、临床医生和研究人员提供人类血小板溶解产品的重要中介机构。这些药房在为再生医学、细胞治疗和研究等各种医疗应用提供人类血小板裂解物方面发挥着至关重要的作用。此外,这些药房确保人类血小板裂解物产品的可用性、品质和及时分发,促进其在临床环境和医院实验室中的使用。
由于生物医学研究活动的活性化、再生医学投资的增加以及对细胞疗法的日益关注,亚太地区在预测期内占据了最大的市场占有率。中国、日本、韩国和印度等国家透过利用医疗基础设施和研究倡议的进步,为 HPL 市场的成长做出了重大贡献。此外,该地区蓬勃发展的生物製药产业,加上其对个人化医疗和再生疗法的关注,为HPL的采用提供了重要的机会,使亚太地区成为HPL在多种生物医学应用中应用的重要场所。 。
由于先进的医疗基础设施、强劲的生物製药行业以及对生物医学研究的大量投资,预计北美在预测期内将实现盈利增长。对个人化医疗的重视和对细胞疗法日益增长的需求正在推动 HPL 在各种生物医学应用中的使用。此外,北美已成为以尖端研发为特征的关键地区,并为 HPL 在生物医学研究和临床环境中广泛采用奠定了坚实的基础。
According to Stratistics MRC, the Global Human Platelet Lysate Market is accounted for $53.75 million in 2023 and is expected to reach $80.29 million by 2030 growing at a CAGR of 5.9% during the forecast period. Human Platelet Lysate (HPL) is a cell culture supplement derived from human blood platelets. It contains growth factors like platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-B), insulin-like growth factor (IGF), and various other proteins that promote cell survival and stimulate tissue regeneration. Moreover, it offers numerous advantages over traditional cell culture supplements like foetal bovine serum (FBS). The growing demand for HPL can be attributed to several driving factors, including its safety, efficiency, and ethical considerations.
According to data published on National Library of Medicine, stated that human platelet lysate (hPL) has higher production cost than foetal bovine serum, which is an alternative option of human platelet lysate (hPL).
Human platelet lysate, renowned for its rich composition of growth factors and cytokines essential for cell growth and proliferation, has emerged as a superior alternative to traditional serum-based media. Its ability to support cell expansion, maintain cellular properties, and promote tissue regeneration has led to increased adoption in regenerative medicine, stem cell research, and tissue engineering. Moreover, the heightened focus on personalised medicine, cell-based therapies, and advancements in drug discovery utilising cell cultures further amplifies the need for human platelet lysate. Therefore, it will propel market growth.
The complex manufacturing process involving the collection, processing, and quality control measures for human platelet lysate results in elevated production expenses compared to traditional serum-based media. These higher costs limit its affordability and accessibility for widespread commercial use in cell culture applications, potentially hindering its adoption. As a result, it will hamper market expansion.
The human platelet lysate's rich composition of growth factors and cytokines essential for cell growth and tissue regeneration aligns perfectly with the requirements of regenerative therapies. As regenerative medicine continues to evolve, HPL emerges as a crucial supplement in cell culture, supporting cell proliferation and maintaining cellular properties necessary for tissue regeneration. Furthermore, its ability to enhance wound healing, stimulate tissue repair, and aid in the development of cell-based therapies positions human platelet lysate as a valuable component in regenerative medicine applications.
Despite reduced xenogeneic contamination compared to foetal bovine serum (FBS), human platelet lysate carries the potential risk of pathogen transmission from human-derived products. Contaminants, such as bacteria or viruses, could compromise the quality and safety of human platelet lysate, impacting its suitability for cell culture applications in research and clinical settings. Hence, it acts as a significant barrier to market expansion.
The COVID-19 pandemic initially caused disruptions in the healthcare sector and restrictions on blood donations, which affected the availability of raw materials for HPL production. Supply chain disruptions and reduced laboratory activities hindered its manufacturing and distribution. However, the pandemic underscored the importance of cell-based therapies, boosting interest in regenerative medicine and cell culture applications where HPL plays a crucial role. As the healthcare sector adapted, the market witnessed a resurgence due to increased research focus on cell-based treatments, potentially driving further demand for HPL.
The heparin-based human platelet lysate segment is estimated to hold the largest share. Heparin serves to prevent clotting during platelet collection and HPL production, ensuring the maintenance of platelet integrity and bioactivity. This specialised variant of HPL offers advantages in cell culture applications by supporting cell growth, proliferation, and viability. The inclusion of heparin enhances the functionality of HPL, making it particularly beneficial in various biomedical fields, including regenerative medicine, stem cell research, and tissue engineering, where uninterrupted platelet bioactivity is essential for optimal cell culture outcomes.
The hospital pharmacies segment is anticipated to have lucrative growth during the forecast period. Hospital pharmacies serve as crucial intermediaries, providing human platelet lysate products to healthcare facilities, clinicians, and researchers. These pharmacies play a pivotal role in supplying human platelet lysate for various medical applications, including regenerative medicine, cell therapy, and research endeavours. Moreover, they ensure the availability, quality, and timely distribution of human platelet lysate products, facilitating their use in clinical settings and research laboratories within hospitals.
Asia Pacific commanded the largest market share during the extrapolated period due to rising biomedical research activities, increasing investments in regenerative medicine, and a growing focus on cell-based therapies. Countries such as China, Japan, South Korea, and India are prominent contributors to HPL market growth, leveraging advancements in healthcare infrastructure and research initiatives. Furthermore, the region's burgeoning biopharmaceutical industry, combined with the emphasis on personalised medicine and regenerative therapies, offers substantial opportunities for HPL adoption, shaping the Asia-Pacific region as a significant hub for HPL utilisation in diverse biomedical applications.
North America is expected to witness profitable growth over the projection period due to advanced healthcare infrastructure, a robust biopharmaceutical industry, and substantial investments in biomedical research. Growing emphasis on personalised medicine and the escalating demand for cell-based therapies bolster the utilisation of HPL in various biomedical applications. Furthermore, North America stands as a key region, characterised by its cutting-edge developments and a strong foundation for the widespread adoption of HPL in biomedical research and clinical settings.
Some of the key players in the Human Platelet Lysate Market include Abbott Laboratories, Astrazeneca Plc., Acella Pharmaceuticals LLC, Cipla Limited, Glenmark Pharmaceuticals Limited, Dabur India Ltd, Johnson and Johnson, Glenmark Pharmaceuticals Limited, Merck KGaA, Pfizer Inc., Novartis International AG, Sanofi SA, Vernalis plc, Aurobindo Pharma Ltd, The Himalaya Drug Company, Beckman Coulter Inc., Sun Pharmaceutical Industries Ltd., Reckitt Benckiser Group PLC, Acadia Pharmaceuticals Inc. and Biocon.
In June 2023, PL BioScience GmbH entered into a Patent License and Assignment Agreement with French company Macopharma S.A.S., granting PL BioScience a worldwide license under Macopharma's patents and introducing PL BioScience to Macopharma's HPL customers for future orders.
In August 2022, StemCyte, Inc. obtained approval from U.S. FDA for their Phase II clinical trial for Post-COVID Syndrome using umbilical cord blood stem cell therapy.
In June 2021, Captivate Bio has signed a partnership agreement with PL BioScience GmbH to exclusively distribute ELAREM human platelet lysate products in the US and Canada, expanding their HPL offerings and enhancing PL BioScience's market presence in North America.