![]() |
市场调查报告书
商品编码
1403517
至 2030 年掌腱膜挛缩症市场预测:按疾病类型、治疗、诊断、给药途径、分销管道、最终用户和地区进行的全球分析Dupuytren Disease Market Forecasts to 2030 - Global Analysis By Disease Type, Treatment, Diagnosis, Route of Administration, Distribution Channel, End User and By Geography |
根据 Stratistics MRC 的数据,2023 年全球掌腱膜挛缩症市场规模为 44 亿美元,预计到 2030 年将达到 68.6 亿美元,预测期内复合年增长率为 6.6%。
掌腱膜挛缩症,也称为Dupuytren氏挛缩,是一种影响手部和手指的疾病。其特征是手掌皮肤下的结缔组织增厚和硬化。掌腱膜挛缩症的主要特征是在手掌上形成结节或肿块,这些结节或肿块可能会发展成组织索,将受影响的手指向内拉。
随着世界人口老化,受掌腱膜挛缩症影响的人数自然也增加,特别是在该病患病率较高的地区。此外,认识的提高和诊断能力的提高有助于更准确、及时地识别掌腱膜挛缩症患者。总体而言,掌腱膜挛缩症的盛行率上升为改善患者照护和新治疗方法的市场开拓创造了机会,从而推动了市场成长。
治疗成本是掌腱膜挛缩症市场的一个重要抑制因素,影响了需求。切除术和筋膜切开术等手术介入以及某些药物治疗涉及大量费用,包括住院费用、外科医生费用和术后护理。此外,掌腱膜挛缩症有復发的可能性,需要额外的治疗并随着时间的推移增加患者的总费用。
治疗方案的技术创新是掌腱膜挛缩症市场的关键驱动力,加速了需求。胶原蛋白酶注射剂的引入彻底改变了掌腱膜挛缩症的治疗方法。胶原酶是一种分解收缩组织的酶,使受影响的手指伸直。这种非手术方法避免了切口和麻醉的需要,为患者提供了一种侵入性较小的治疗选择。
掌腱膜挛缩症在患者之间表现出很大的异质性,其严重程度、受影响的手腕关节和治疗反应各不相同。这种变异性使得预测治疗结果和为每个人选择最合适的治疗变得困难。在某些患者中,儘管经过治疗,挛缩的改善可能有限或復发,需要额外的干预措施或合併治疗方法。因此,掌腱膜挛缩症市场的治疗选择有限,对市场成长构成挑战。
COVID-19 的爆发对双相疾病市场产生了重大影响,带来了影响患者照护和市场动态的挑战。医疗保健系统优先分配资源来应对这一流行病,扰乱了常规医疗服务并延迟了掌腱膜挛缩症的诊断和治疗。此外,疫情期间的供应链中断和製造挑战正在影响 Dupuytren 独特治疗方法的可用性和分销。
预计放射线治疗领域将占最大份额。放射线治疗使用高能量辐射来瞄准和抑制与掌腱膜挛缩症相关的异常组织生长。这种非侵入性治疗方法特别适用于疾病晚期的患者,其特征是出现影响手部功能的挛缩和结节。当多个手指受到影响或手术后復发时尤其有效。
预计肠外给药领域在预测期内将出现良好的成长。在掌腱膜挛缩症中,肠胃外给药途径在绕过胃肠道直接向患者体内提供治疗性介入方面发挥着至关重要的作用。这种直接方法可确保治疗药物的快速吸收和分布,从而在疾病症状管理中发挥最佳功效。此外,肠胃外途径最大限度地降低了药物在胃肠道环境中降解和改变的风险,从而提高了生物有效性。
在估计期间,北美占据了最大的市场占有率。该地区拥有先进的医疗基础设施、完善的法律规范以及掌腱膜挛缩症的高盛行率,尤其是在人口老化地区。该地区的医疗保健环境鼓励采用先进的外科手术、注射治疗和非侵入性选择。此外,该地区的研究机构、製药公司和医疗保健提供者之间的合作正在促进新治疗方法的开发。
预计亚太地区在预测期内将实现盈利成长。该地区发生了重大转变,采用了先进的医疗技术和治疗方法掌腱膜挛缩症的方法。不断增加的研究倡议、区域和国际医疗保健营业单位之间的合作以及不断发展的医疗保健政策都有助于创新治疗方法的开发和采用。该地区的市场开拓进一步受到经济发展、医疗成本降低以及更注重以患者为中心的护理的推动。
According to Stratistics MRC, the Global Dupuytren Disease Market is accounted for $4.40 billion in 2023 and is expected to reach $6.86 billion by 2030 growing at a CAGR of 6.6% during the forecast period. Dupuytren's disease, also known as Dupuytren's contracture, is a medical condition that affects the hands and fingers. It is characterized by the thickening and tightening of the connective tissue beneath the skin in the palm of the hand. The primary feature of Dupuytren's disease is the development of nodules or lumps in the palm, which may progress to form cords of tissue that pull the affected fingers inward.
As the global population ages, particularly in regions with a higher prevalence of this condition, there is a natural rise in the number of individuals affected by Dupuytren's disease. Moreover, heightened awareness and improved diagnostic capabilities contribute to the more accurate and timely identification of Dupuytren's disease cases. Overall, the escalating incidence of Dupuytren's disease propels market growth by creating opportunities for improved patient care and the development of novel treatment modalities.
The cost of treatment serves as a notable restraint in the Dupuytren's disease market, impacting the demand. Surgical interventions, such as fasciectomy or fasciotomy, and certain pharmaceutical treatments involve substantial costs; include hospitalization, surgeon fees, and post-operative care. Moreover, the potential for recurrence in Dupuytren's disease necessitates additional treatments, amplifying the overall cost for patients over time.
Technological innovations in treatment options are a significant driver in the Dupuytren disease market, accelerating the demand. The introduction of collagenase injections has revolutionized the treatment of Dupuytren disease. Collagenase is an enzyme that can break down the contracted tissue, enabling the straightening of the affected fingers. This non-surgical approach avoids the need for incisions or anaesthesia and provides patients with a less-invasive treatment option.
Dupuytren disease exhibits significant heterogeneity among patients, with variations in disease severity, affected hand joints, and response to treatments. This variability makes it challenging to predict treatment outcomes and select the most appropriate intervention for each individual. Some patients may experience limited improvement or recurrence of contractures even after undergoing treatment, leading to the need for additional interventions or a combination of treatment approaches. Therefore, the limited treatment options in the dupuytren disease market pose a challenge to market growth.
The COVID-19 pandemic has significantly impacted the Dupuytren disease market, introducing challenges that have influenced both patient care and market dynamics. The healthcare system's prioritization of resources toward managing the pandemic has led to disruptions in routine medical services, delaying the diagnosis and treatment of Dupuytren disease. Additionally, supply chain disruptions and manufacturing challenges during the pandemic have affected the availability and distribution of Dupuytren-specific treatments.
The radiation therapy segment is estimated to hold the largest share. Radiation therapy involves the use of high-energy radiation to target and reduce abnormal tissue growth associated with Dupuytren's disease. This non-invasive treatment modality is particularly considered for individuals with advanced stages of the disease, characterized by contractures and nodules impacting hand function. It is especially beneficial in cases where multiple fingers are affected or when the disease recurs after surgery.
The parenteral segment is anticipated to have lucrative growth during the forecast period. In Dupuytren's disease the parenteral route of administration plays a pivotal role in delivering therapeutic interventions directly into the patient's system, bypassing the gastrointestinal tract. This direct approach ensures rapid absorption and distribution of the therapeutic agent, allowing for optimal efficacy in managing the disease's symptoms. Moreover, the parenteral route minimizes the risk of degradation or alteration of the drug in the gastrointestinal environment, enhancing its bioavailability.
North America commanded the largest market share during the extrapolated period. The region comprises advanced healthcare infrastructure, a well-established regulatory framework, and a high prevalence of Dupuytren's disease, particularly in the aging population. The region's healthcare landscape encourages the adoption of advanced surgical procedures, injectable treatments, and non-invasive options. Moreover, collaborations between research institutions, pharmaceutical companies, and healthcare providers contribute to the development of novel therapies in this region.
Asia Pacific is expected to witness profitable growth over the projection period. In this region, there is a notable shift toward embracing advanced medical technologies and therapies for Dupuytren's disease. Increased research initiatives, collaborations between regional and international healthcare entities, and evolving healthcare policies contribute to the development and adoption of innovative treatment options. The market's growth in this region is further propelled by economic development, improved healthcare affordability, and a heightened focus on patient-centric care.
Some of the key players in the Dupuytren Disease Market include Pfizer Inc, AstraZeneca, Endo International plc, LEO Pharma A/S, Spear Pharmaceuticals, Hikma Pharmaceuticals PLC, Bristol-Meyers Squibb Company, Fresenius Kabi AG, GSK plc, Actiza Pharmaceutical Private Limited, Nantong Jinghua Pharmaceutical Co., Ltd, Novartis AG, Bayer AG., Johnson & Johnson Services Ltd. and Aurobindo Pharma.
In August 2023, Hikma Pharmaceuticals PLC (Hikma), the multinational pharmaceutical company, announces a new strategic partnership and exclusive licensing agreement with SK Biopharmaceuticals, a global biotech company focused on the development of treatments for central nervous system (CNS) disorders and oncology, for the Middle East and North Africa.
In January 2022, Pfizer Inc. and BioNTech SE announced a new research, development and commercialization collaboration to develop a potential first mRNA-based vaccine for the prevention of shingles, a debilitating, disfiguring and painful disease that impacts about one in three people in the United States during their lifetime.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.