市场调查报告书
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1462708
到 2030 年 LAMP(恒温环型核酸扩增)市场预测:按产品类型、类型、技术、应用、最终用户和地区进行的全球分析Loop-mediated Isothermal Amplification Market Forecasts to 2030 - Global Analysis By Product Type (Instruments, Kits & Reagents and Other Product Types), Type, Technology, Application, End User and By Geography |
根据 Stratistics MRC 预测,2023 年全球 LAMP(恒温环型核酸扩增)市场规模将达到 1.035 亿美元,2030 年将达到 1.651 亿美元,预测期内复合年增长率为 6.9%。
恒温环型核酸扩增(LAMP)是一种核酸扩增技术,用于在恆温条件下快速复製 DNA。使用四到六个针对 DNA 多个区域(包括环结构)的引子来启动链置换和扩增。 LAMP 反应通常在 60 至 65°C 之间进行,因此不需要热感循环设备。 LAMP方法可在30至60分钟内产生大量DNA,可快速检测病原体和基因突变等目标序列。由于其简单、快速、特异性高,广泛应用于临床诊断、环境监测、食品安全检测等领域。
对快速、准确诊断的需求不断增长
对快速、准确诊断的日益增长的需求正在推动 LAMP 市场的成长。医疗保健提供者正在采用 LAMP(恒温环型核酸扩增)技术来满足快速检测的需求,特别是在及时诊断至关重要的情况下,例如感染疾病爆发和紧急情况。公司正在投资研发,以提高其 LAMP(恒温环型核酸扩增)检测的灵敏度、特异性和多重功能。因此,开发了先进的基于环介导等温扩增的诊断平台和试剂,推动了市场成长。
有限的复用能力
由于多重检测能力有限,必须透过单独的反应来检测每个目标,从而增加了诊断所需的时间、成本和资源。这种效率和成本效益的降低可能会阻止医疗保健提供者采用 LAMP(恒温环型核酸扩增)技术,特别是在高通量和资源效率很重要的环境中。因此,LAMP(恒温环型核酸扩增)技术有限的多路復用能力可能使其在市场上处于竞争劣势,从而鼓励医疗保健提供者考虑选择更能满足其多路復用需求的替代技术,从而阻碍市场成长。
慢性病增加
慢性病通常需要定期监测和早期发现,以便有效管理和治疗。人们越来越需要快速、准确的诊断解决方案来及早发现这些疾病。 LAMP方法快速、灵敏,适合诊断慢性疾病,可及时介入并改善患者预后。此外,世界各地的政府和医疗机构正在实施筛检计划,以及早发现慢性病,从而减轻疾病负担和医疗费用。
资源有限的环境中基础设施有限
资源有限的环境往往缺乏足够的医疗基础设施,例如检测设施、训练有素的人员和可靠的电力供应。在这种情况下,需要专门的设备和训练有素的人员来进行 LAMP(恒温环型核酸扩增)检测,这可能会带来挑战并限制该技术的采用。此外,对不断电系统和试剂气候控制储存条件的需求进一步增加了成本负担,并使 LAMP 技术在此类环境中不太可行。
COVID-19 的影响
COVID-19 大流行加速了 LAMP(恒温环型核酸扩增)技术的采用,以进行快速、分散的测试。 LAMP 方法简单、快速且准确,使其成为诊断 COVID-19 的宝贵工具,尤其是在资源有限和照护现场环境中。随着医疗保健寻求有效的测试解决方案来限制病毒的传播,对基于 LAMP 的检测和平台的需求正在迅速增加。然而,供应链中断、监管挑战以及其他诊断技术的竞争也正在影响疫情期间的 LAMP 市场动态。整体而言,COVID-19 既推动了 LAMP 市场的成长,也带来了挑战。
DNA(去氧核糖核酸)片段预计将成为预测期内最大的片段。
DNA(去氧核糖核酸)片段旨在扩增 DNA 序列,从而实现有利的生长。 DNA(去氧核糖核酸)片段旨在扩增 DNA 序列,从而实现有利的生长。 DNA(去氧核糖核酸)片段广泛应用于分子生物学研究、临床诊断以及需要快速、灵敏检测 DNA 的各种其他领域。此外,在临床诊断中,特定DNA序列的存在或不存在通常表示疾病状态、基因突变或病原体感染。 LAMP(恒温环型核酸扩增)检测旨在以高灵敏度和特异性检测这些 DNA 标靶。因此,能够准确扩增和检测目标 DNA 序列的 LAMP(恒温环型核酸扩增)检测的可用性正在影响 LAMP 市场在诊断应用中的采用和成长。
逆转录 LAMP 细分市场预计在预测期内复合年增长率最高
逆转录LAMP领域预计在预测期内将出现最高的复合年增长率,因为它允许扩增除DNA以外的RNA靶标,从而显着扩大LAMP技术的应用范围。这项扩展使得能够检测 RNA 病毒、基于 RNA 的生物标记和 RNA 转录本,为感染疾病诊断、基因表现分析和 RNA 研究提供新的机会。此外,这种能力对于基因表现谱研究、生物标记发现以及细胞对刺激和治疗的反应监测非常有用,所有上述因素都在推动市场成长。
结核病、登革热、疟疾等感染疾病以及 COVID-19 等新兴感染疾病在亚太地区盛行,推动了对快速诊断解决方案的需求。它提供快速、准确结果的能力对于控制疾病爆发和应对公共卫生挑战特别有价值。此外,日本、韩国、中国和印度等国家强大的生物技术和生命科学产业正在推动 LAMP(恒温环型核酸扩增)技术的研发活动,也推动了市场的成长。
儘管医疗保健标准很高,但北美仍面临流感、莱姆病和性行为感染传染病等感染疾病的挑战。 LAMP 技术快速、准确的诊断能力对该地区的医疗保健提供者很有吸引力。北美对分散式检查解决方案的需求不断增加,推动了市场成长,特别是在偏远和服务不足的地区以及公共卫生紧急情况期间。
According to Stratistics MRC, the Global Loop-mediated Isothermal Amplification Market is accounted for $103.5 million in 2023 and is expected to reach $165.1 million by 2030 growing at a CAGR of 6.9% during the forecast period. Loop-mediated isothermal amplification (LAMP) is a nucleic acid amplification technique used to rapidly replicate DNA under constant temperature conditions. It employs four to six primers targeting multiple regions of the DNA, including loop structures, which initiate strand displacement and amplification. LAMP reactions typically occur between 60-65°C, eliminating the need for thermal cycling equipment. By producing large amounts of DNA within 30-60 minutes, LAMP enables rapid detection of target sequences, such as pathogens or genetic variations. Its simplicity, speed, and high specificity make it valuable in various fields, including clinical diagnostics, environmental monitoring, and food safety testing.
Rising demand for rapid and accurate diagnostics
The increasing need for quick and precise diagnostics has propelled the growth of the LAMP market. Healthcare providers are adopting loop-mediated isothermal amplification technology to meet the demand for rapid testing, especially in scenarios where timely diagnosis is critical, such as infectious disease outbreaks or emergency situations. Companies are investing in research and development to improve the sensitivity, specificity, and multiplexing capabilities of loop-mediated isothermal amplification assays. This has led to the development of advanced loop-mediated isothermal amplification-based diagnostic platforms and reagents boosting the growth of the market.
Limited multiplexing capability
Limited multiplexing capability means that each target must be detected in a separate reaction, increasing the time, cost, and resources required for diagnostics. This reduced efficiency and cost-effectiveness can deter healthcare providers from adopting loop-mediated isothermal amplification technology, especially in settings where high throughput and resource efficiency are crucial. Thus the limited multiplexing capability of loop-mediated isothermal amplification technology can put it at a competitive disadvantage in the market, as healthcare providers may opt for alternative technologies that better meet their multiplexing needs hamper the market growth.
Increasing prevalence of chronic diseases
Chronic diseases often require regular monitoring and early detection for effective management and treatment. The need for rapid and accurate diagnostic solutions to detect these diseases at an early stage has increased. LAMP technology, with its rapid turnaround time and high sensitivity, is well-suited for diagnosing chronic conditions, enabling timely intervention and improved patient outcomes. Furthermore governments and healthcare organizations worldwide are implementing screening programs to detect chronic diseases early, thereby reducing disease burden and healthcare costs.
Limited infrastructure in resource-limited settings
Resource-limited settings often lack adequate healthcare infrastructure, including laboratory facilities, trained personnel, and reliable electricity supply. The requirement for specialized equipment and trained personnel to conduct loop-mediated isothermal amplification assays may pose accessibility challenges in such settings, limiting the adoption of this technology. Additionally, the need for uninterrupted power supply and climate-controlled storage conditions for reagents further adds to the cost burden, making LAMP technology less feasible in these environments.
Covid-19 Impact
The COVID-19 pandemic has accelerated the adoption of Loop-mediated Isothermal Amplification (LAMP) technology for rapid and decentralized testing. LAMP's simplicity, speed, and accuracy have made it a valuable tool for COVID-19 diagnostics, especially in resource-limited settings and point-of-care environments. The demand for LAMP-based assays and platforms has surged as healthcare systems seek efficient testing solutions to curb the spread of the virus. However, supply chain disruptions, regulatory challenges, and competition from other diagnostic technologies have also influenced the LAMP market dynamics during the pandemic. Overall, COVID-19 has both propelled and challenged the growth of the LAMP market.
The DNA (deoxyribonucleic acid) segment is expected to be the largest during the forecast period
The DNA (deoxyribonucleic acid) segment is estimated to have a lucrative growth, as it is designed to amplify DNA sequences. It is widely used in molecular biology research, clinical diagnostics, and various other fields where rapid and sensitive detection of DNA is required. Moreover in clinical diagnostics, the presence or absence of specific DNA sequences is often indicative of disease states, genetic mutations, or pathogen infections. Loop-mediated isothermal amplification assays are designed to detect these DNA targets with high sensitivity and specificity. Therefore, the availability of loop-mediated isothermal amplification assays that can accurately amplify and detect target DNA sequences influences the adoption and growth of the LAMP market in diagnostic applications.
The reverse transcription LAMP segment is expected to have the highest CAGR during the forecast period
The reverse transcription LAMP segment is anticipated to witness the highest CAGR growth during the forecast period, as it allows for the amplification of RNA targets, in addition to DNA, which significantly broadens the application spectrum of LAMP technology. This expansion enables the detection of RNA viruses, RNA-based biomarkers, and RNA transcripts, opening up new opportunities in infectious disease diagnosis, gene expression analysis, and RNA research. Furthermore this capability is useful in gene expression profiling studies, biomarker discovery, and monitoring cellular responses to stimuli or treatments thus all the above factors drive the market growth.
Asia Pacific is projected to hold the largest market share during the forecast period owing to the prevalence of infectious diseases in the Asia Pacific region, including tuberculosis, dengue, malaria, and emerging infectious diseases like COVID-19, is driving the demand for rapid diagnostic solutions. Its ability to provide quick and accurate results is particularly valuable in controlling disease outbreaks and managing public health challenges. Additionally the presence of a robust biotechnology and life sciences industry in countries like Japan, South Korea, China, and India fosters research and development activities in loop-mediated isothermal amplification technology propel the growth of the market.
North America is projected to have the highest CAGR over the forecast period, despite high healthcare standards; North America still faces challenges related to infectious diseases such as influenza, Lyme disease, and sexually transmitted infections. LAMP technology's rapid and accurate diagnostic capabilities make it attractive for healthcare providers in the region. The demand for decentralized testing solutions is increasing in North America, especially in remote or underserved areas and during public health emergencies encourage the growth of the market.
Key players in the market
Some of the key players in the Loop-mediated Isothermal Amplification Market include Bio-Rad Laboratories, Inc., CapitalBio, Deaou Biotechnology, Eiken Chemical , Excellgen Inc, GENESIS Dhelix, HiberGene Diagnostics, Jena Bioscience GmbH, Mast Group Ltd., Merck KGaA, Meridian Bioscience, Inc., New England Biolabs, NIPPON GENE CO., LTD, OptiGene, QIAGEN N.V, Singuway and Thermo Fisher Scientific
In March 2024, Thermo Fisher Scientific Launches CorEvitas Clinical Registry in Generalized Pustular Psoriasis. This registry, which is open to enrollment, is CorEvitas' 10th syndicated disease registry and addresses an unmet need for real-world evidence (RWE) related to the clinical and patient-reported outcomes of patients with GPP.
In January 2024, Nippon Gene Co., Ltd. announced the National Agriculture and Food Research Organization (NARO) have developed two molecular-based diagnostic kits for Johne's disease.
In July 2023, Bio-Rad and QIAGEN Announce Patent Settlement and Cross-Licensing Agreement. The settlement provides for a cross-licensing agreement between Bio-Rad and QIAGEN granting each company mutual rights to their respective digital PCR technologies.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.