市场调查报告书
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1503432
2030 年冷冻电镜市场预测:按产品、电压、技术、应用、最终用户和地区进行的全球分析Cryo-electron Microscope Market Forecasts to 2030 - Global Analysis By Product (Instruments, Software and Services), Voltage (120 KV, 200 KV and 300 KV), Technology, Application, End User and By Geography |
根据 Stratistics MRC 的数据,2024 年全球冷冻电子显微镜市场规模为 13.5 亿美元,预计在预测期内复合年增长率为 10.7%,到 2030 年将达到 24.8 亿美元。
冷冻电子显微镜 (Cryo-EM) 是结构生物学中使用的强大工具,可以近原子分辨率可视化蛋白质、病毒和其他生物大分子。该技术允许样品在极低的温度下快速冷冻,保留其自然结构,无需染色或固定。冷冻电子显微镜使用电子束对样品进行成像,并使用先进的计算技术将其重建为详细的 3D 模型。此方法在研究难以结晶的复杂分子结构时特别有用,并提供对其功能和机制的重要见解。
对结构生物学的需求不断增长
对结构生物学不断增长的需求极大地推动了冷冻电子显微镜(Cryo-EM)市场的发展。结构生物学需要生物分子结构的详细视觉化,以便了解它们的功能和相互作用。冷冻电子显微镜可以以近原子分辨率观察这些结构,促进药物发现、疾病研究和生物技术的突破。冷冻电子显微镜解析复杂生物分子的精确度和效率是无与伦比的,使其成为现代结构生物学的重要工具。
维护和营运成本
冷冻电子显微镜 (Cryo-EM) 市场受到高昂的维护和营运成本的严重限制。这些成本包括定期校准的需要、液态氮等昂贵的消耗品以及需要熟练技术人员的专业维护服务。此外,显微镜需要受控的环境,这增加了设备和公用事业成本。设备的复杂性需要持续的操作员培训,进一步增加了营运成本。这种财务负担可能会阻止小型机构和研究中心采用冷冻电子显微镜技术。
拓展新的应用领域
扩展到新的应用领域是冷冻电子显微镜 (cryo-EM) 市场的重大机会。冷冻电子显微镜越来越多地应用于结构生物学、材料科学和奈米技术等领域。冷冻电子显微镜可以提供接近原子分辨率的生物分子和复杂材料的高解析度3D影像,在药物发现、病毒学研究以及新型奈米材料的研发中具有不可估量的价值。冷冻电子显微镜在解决跨学科的复杂科学问题方面的多功能性凸显了其不断扩大的应用潜力。
技术复杂性
冷冻电子显微镜 (Cryo-EM) 市场中技术复杂性的威胁源自于这些设备的复杂设计和复杂操作。冷冻电子显微镜系统需要先进的知识来设定、维护和操作,限制了其只能由高度专业的人员使用。此外,低温、光电和成像技术的整合需要多个科学学科的高水平专业知识。高成本和定期校准的需要使资源匮乏的实验室的可及性和挑战传播更加复杂。
COVID-19 大流行加速了冷冻电子显微镜 (Cryo-EM) 在研究和诊断应用中的需求和采用,对冷冻电子显微镜 (Cryo-EM) 市场产生了重大影响。了解 SARS-CoV-2 病毒结构和开发疫苗的迫切需求导致对冷冻电子显微镜等先进成像技术的投资增加。许多研究机构和製药公司扩大了其冷冻电子显微镜设施,以实现对病毒和蛋白质的快速结构分析。因此,儘管供应链和製造因停工而中断,但市场仍在成长。
核磁共振 (NMR) 显微镜产业预计在预测期内规模最大
核磁共振 (NMR) 显微镜在冷冻电子显微镜市场的成长归因于其提供生物分子天然状态高解析度结构资讯的独特能力。核磁共振透过提供对原子层级上的动态过程和分子间相互作用的洞察来补充冷冻电子显微镜。这种协同效应使研究人员能够全面了解复杂的生物系统,从而增加了对整合解决方案的需求。此外,核磁共振技术的进步,例如磁场强度的增加和灵敏度的提高,正在提高与冷冻电镜工作流程的兼容性,进一步促进其采用。
奈米技术产业预计在预测期内复合年增长率最高
奈米技术在冷冻电子显微镜 (Cryo-EM) 市场中的扩展是由其无与伦比的以卓越分辨率可视化奈米级结构的能力推动的。随着研究人员深入研究奈米科学领域,对冷冻电子显微镜技术的需求正在迅速增加。其在低温下研究生物样本的能力提供了对分子结构的宝贵见解,并且在药物发现和材料科学中很有用。此外,奈米材料合成和表征的进步需要高解析度成像工具,例如冷冻电子显微镜。奈米技术和冷冻电子显微镜之间的协同效应正在推动市场成长并促进各个科学领域的创新。
由于多种因素,北美地区的冷冻电镜市场正在经历显着成长。该地区是大型製药企业和生物技术公司的所在地,推动了药物发现和开发对先进成像技术的需求。此外,北美学术研究机构正积极将冷冻电镜应用于结构生物学研究,进一步推动市场成长。该地区强大的基础设施、先进的技术和有利的法规环境也有助于冷冻电镜市场的扩张。此外,产业参与者和研究机构之间的合作正在推动创新并加速市场渗透。
由于多种因素,亚太地区冷冻电镜市场正在经历强劲成长。各科学领域的研发活动投资不断增加,推动了对冷冻电子显微镜等先进成像技术的需求。製药和生物技术行业越来越多地采用冷冻电子显微镜技术进行药物发现和结构生物学研究,这进一步推动了市场的成长。此外,主要市场参与者在该地区扩大业务的存在以及政府促进科学研究的倡议正在推动市场扩张。
According to Stratistics MRC, the Global Cryo-electron Microscope Market is accounted for $1.35 billion in 2024 and is expected to reach $2.48 billion by 2030 growing at a CAGR of 10.7% during the forecast period. A cryo-electron microscope (Cryo-EM) is a powerful tool used in structural biology to visualize proteins, viruses, and other biological macromolecules at near-atomic resolution. This technique involves rapidly freezing samples at cryogenic temperatures to preserve their natural structure without the need for staining or fixing. Cryo-EM uses electron beams to image the samples, which are then reconstructed into detailed 3D models through advanced computational methods. This method is particularly valuable for studying complex molecular structures that are difficult to crystallize, providing critical insights into their function and mechanisms.
Growing demand for structural biology
The growing demand for structural biology is significantly driving the cryo-electron microscope (cryo-EM) market. Structural biology requires detailed visualization of biomolecular structures to understand their functions and interactions. Cryo-EM allows scientists to observe these structures at near-atomic resolution, facilitating breakthroughs in drug discovery, disease research, and biotechnology. The precision and efficiency of cryo-EM in resolving complex biological molecules are unmatched, making it an indispensable tool in modern structural biology.
Maintenance and operational costs
The cryo-electron microscope (Cryo-EM) market is significantly restrained by high maintenance and operational costs. These costs include the need for regular calibration, expensive consumables like liquid nitrogen, and specialized maintenance services that require skilled technicians. Additionally, the microscopes demand a controlled environment, adding to the costs of facilities and utilities. The complexity of the equipment necessitates ongoing training for operators, further increasing operational expenses. These financial burdens can deter smaller institutions and research centers from adopting cryo-EM technology.
Expansion into new application areas
The expansion into new application areas presents a significant opportunity for the cryo-electron microscope (cryo-EM) market. Cryo-EM is increasingly being utilized in diverse fields such as structural biology, materials science, and nanotechnology. Its ability to provide high-resolution, three-dimensional images of biomolecules and complex materials at near-atomic resolutions makes it invaluable for drug discovery, virology research, and the development of novel nanomaterials. The versatility of cryo-EM in addressing complex scientific questions across various domains underscores its expanding application potential.
Technical complexity
The technical complexity threat in the cryo-electron microscope (cryo-EM) market arises from the intricate design and sophisticated operation of these instruments. Cryo-EM systems require advanced knowledge for setup, maintenance, and operation, limiting their use to highly specialized personnel. Additionally, the integration of cryogenics, electron optics, and imaging technology demands significant expertise in multiple scientific domains. The high cost and need for regular calibration further complicate accessibility, posing challenges for widespread adoption in less-resourced laboratories.
The COVID-19 pandemic significantly impacted the cryo-electron microscope (Cryo-EM) market by accelerating its demand and adoption in research and diagnostic applications. The urgent need to understand the SARS-CoV-2 virus structure and develop vaccines prompted increased investment in advanced imaging technologies like Cryo-EM. Many research institutions and pharmaceutical companies expanded their cryo-EM facilities to facilitate rapid virus and protein structure analysis. Consequently, the market experienced growth despite disruptions in supply chains and manufacturing due to lockdowns.
The nuclear magnetic resonance (NMR) microscopy segment is expected to be the largest during the forecast period
The growth of nuclear magnetic resonance (NMR) microscopy within the cryo-electron microscope market stems from its unique ability to provide high-resolution structural information about biological molecules in their native states. NMR complements cryo-EM by offering insights into dynamic processes and molecular interactions at the atomic level. This synergy enables researchers to gain a comprehensive understanding of complex biological systems, driving demand for integrated solutions. Additionally, advancements in NMR technology, such as higher magnetic field strengths and improved sensitivity, enhance its compatibility with cryo-EM workflows, further fueling its adoption.
The Nanotechnology segment is expected to have the highest CAGR during the forecast period
Nanotechnology's expansion in the cryo-electron microscope (Cryo-EM) market is fueled by its unparalleled ability to visualize nanoscale structures with exceptional resolution. As researchers delve deeper into the realm of nanoscience, the demand for cryo-EM technology has surged. Its capability to study biological samples at cryogenic temperatures provides invaluable insights into molecular structures, aiding drug discovery and material science. Moreover, advancements in nanomaterial synthesis and characterization necessitate high-resolution imaging tools like Cryo-EM. This synergy between nanotechnology and cryo-EM is propelling the market's growth and fostering innovation in various scientific disciplines.
The North American region has experienced significant growth in the cryo-electron microscope market due to several factors. There's a strong presence of leading pharmaceutical and biotechnology companies in the region, driving demand for advanced imaging technologies for drug discovery and development. Additionally, academic and research institutions in North America have been actively adopting cryo-EM for structural biology studies, further boosting market growth. The region's robust infrastructure, technological advancements, and favorable regulatory environment also contribute to the expansion of the cryo-EM market. Moreover, collaborations between industry players and research organizations foster innovation and accelerate market penetration.
The Asia-Pacific region has witnessed significant growth in the Cryo-electron Microscope market due to several factors. Increased investment in research and development activities across various scientific disciplines has propelled the demand for advanced imaging technologies like cryo-electron microscopy. Rising adoption of cryo-EM techniques in pharmaceutical and biotechnology industries for drug discovery and structural biology studies has further stimulated market growth. Additionally, the presence of key market players expanding their operations in the region, coupled with government initiatives promoting scientific research, has fueled market expansion.
Key players in the market
Some of the key players in Cryo-electron Microscope market include AstraZeneca PLC, Carl Zeiss AG, Charles River Laboratories International, Inc., Delmic B.V., Electron Microscopy Sciences, Gatan, Inc., Hitachi High-Tech Corporation, Intertek Group PLC, Jena Bioscience GmbH, Jeol Ltd., Judges Scientific PLC, Leica Microsystems by Danaher Corporation, NanoImaging Services, Inc., Spectris PLC, SPT Labtech Ltd. and Thermo Fisher Scientific Inc.
In June 2024, US lab equipment and services business Thermo Fisher Scientific has opened a new clinical and commercial ultra-cold facility in Bleiswijk, Netherlands. The new site specialises in ambient to cryogenic storage, clinical and commercial packaging, labelling and distribution, and clinical qualified person release services.
In April 2024, Total Quality Assurance (TQA) provider Intertek has entered a strategic partnership with software company Trace For Good to launch a software as a service (SaaS) platform to improve traceability and sustainability in textile and apparel supply chains. The platform's feature is said to include supply chain mapping and traceability at the product level, verification of claims and documents, supplier risk assessments, and support in eco-design and Life Cycle Assessment.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.