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市场调查报告书
商品编码
1636653
2030 年空间基因组学和转录组学市场预测:按产品、技术、应用、最终用户和地区进行的全球分析Spatial Genomics and Transcriptomics Market Forecasts to 2030 - Global Analysis By Product (Consumables, Instruments, Software & Analytics, Services and Other Products), Technology, Application, End User and By Geography |
根据 Stratistics MRC 的数据,全球空间基因组学和转录组学市场预计在 2024 年价值 3.032 亿美元,到 2030 年将达到 6.725 亿美元,预测期内的复合年增长率为 14.2%。
空间基因组学和转录组学是一种将空间资讯与分子资料相结合以高解析度研究细胞和组织的组织、功能和动态的先进技术。这些技术提供了对基因表现和调控的洞察,使研究人员能够绘製生物样本内 DNA 和 RNA 的空间分布图。空间基因组学专注于了解细胞核内基因组的3D结构和组织,而转录组学则捕捉 RNA 转录本在组织中的空间分布,提供原位基因表现模式的全面视图。
根据美国疾病管制中心(CDC)估计,光是 2020 年美国医院就发生了 170 万例医院内感染疾病。然而,报告发现,因手术而感染疾病的患者平均住院时间要多出 6.5 天,出院后再次入院的可能性高出五倍。
强调个人化医疗
个人化医疗旨在根据患者的基因、分子和细胞特征为其提供量身定制的医疗服务。为此,必须利用空间基因组学和转录组学来研究特定组织区域的基因活动并揭示组织内异质性。空间工具可以绘製不同组织区域细胞之间复杂的相互作用,有助于识别癌症、神经系统疾病和自体免疫疾病等疾病的疾病机制和治疗目标。
资料分析的复杂性
空间基因组学和转录组学会产生大量复杂的资料,需要专门的工具和专业知识。挑战包括需要专业知识、缺乏可用的工具、漫长的学习曲线以及资源限制。临床医生和分子生物学家等非专业人士很难将这些技术融入他们的工作流程中。可存取的工具通常是专有的或开放原始码的,但需要高级编码技能,限制了非技术用户的可用性。此外,小型实验室可能缺乏预算或人力来聘请生物资讯学家或投资于他们的培训。
成像、定序和计算工具的持续创新
超高解析度和光片显微镜等现代成像技术可以详细地可视化组织中的基因表现和分子相互作用。活细胞成像提供了对即时细胞和分子过程的动态洞察,以增强转化研究应用。改进的成像工具将吸引新的研究人员,推动发育生物学、肿瘤学和神经科学等领域对空间基因组学技术的需求,从而促进市场成长。
缺乏标准化通讯协定和基准
空间基因组学和转录组学涉及复杂的工作流程,包括组织准备、成像、定序和资料分析。由于缺乏通用协议,结果可能不一致。样品製备的变化,包括组织固定方法、切片技术、储存条件、成像和定序之间的差异以及资料分析的挑战,可能导致基因表现表现谱、空间分辨率和资料品质的变化。此外,资料处理和解释的计算流程可能会引入影响基因表现资料可靠性的偏差。
COVID-19 的影响
COVID-19 疫情对空间基因组学和转录组学市场产生了重大影响,加速了采用先进的分子技术来了解病毒机制和宿主反应。研究人员正在利用空间基因组学来探索 SARS-CoV-2 与人体组织的相互作用,这推动了对尖端工具的需求。但疫情也导致供应链中断。儘管存在这些挑战,但对 COVID-19 和其他疾病的研究的迫切需求正在刺激创新和投资,对市场的长期成长前景产生积极影响。
碳纤维市场预计将成为预测期内最大的市场
在预测期内,高压釜部分预计将占据最大的市场占有率,因为显微镜载物台、镜头和支架等高性能光学元件可以提高成像系统的准确性和稳定性,尤其是在空间转录组学方面。碳纤维整体式装置功能强大且经久耐用,使空间基因组学工具更加高效,对研究人员更具吸引力,并有可能增加其在实验室、医院和研究机构的应用。
预计高压釜处理部门在预测期内将实现最高复合年增长率
预计预测期内高压釜处理部分将以最高的复合年增长率成长。高压釜对于与组织样本和基因组材料接触的仪器的消毒以及防止空间转录组学实验期间的污染至关重要。它还透过使蛋白质变性和稳定组织来帮助组织固定,保持组织切片的空间完整性,这对于准确的空间基因表现研究至关重要。灭菌和组织固定对于有效的基因表现研究至关重要。
预计预测期内北美地区将占据最大的市场占有率。这是因为先进的医疗保健系统能够将空间基因组学融入临床实践,从而实现肿瘤学、神经病学和免疫学领域的精准医疗。北美的医院和诊断中心拥有部署复杂技术的能力和财力,使个人化医疗成为现实。空间基因组学可以帮助发现生物标记、开发药物和标靶治疗,特别是对于癌症和神经系统疾病等复杂疾病。
预计亚太地区将在整个预测期内以最高的复合年增长率成长,这主要得益于中国、印度、日本和韩国对基因组研究的投资,尤其是个人化医疗、癌症研究和感染疾病基因组学。这些国家正致力于基因组定序、精准医疗和太空转录组学,以从组织特异性层级了解疾病生物学。亚太地区主要研究中心,包括北京基因组研究所、生物资讯研究所、理化学研究所等。
According to Stratistics MRC, the Global Spatial Genomics & Transcriptomics Market is accounted for $303.2 million in 2024 and is expected to reach $672.5 million by 2030 growing at a CAGR of 14.2% during the forecast period. Spatial genomics and transcriptomics are advanced technologies that combine spatial information with molecular data to study the organization, function, and dynamics of cells and tissues at high resolution. They provide insights into gene expression and regulation in their native spatial context, allowing researchers to map the spatial distribution of DNA and RNA within a biological sample. Spatial genomics focuses on understanding the three-dimensional structure and organization of the genome within the nucleus, while transcriptomics captures the spatial distribution of RNA transcripts across tissues, providing a comprehensive view of gene expression patterns in situ.
According to the Centers for Disease Control (CDC) In 2020, In American Hospitals alone, hospital-acquired infections alone accounted for an estimated 1.7 million infections. However, the report states that patients who acquire infections from surgery spend, on average, an additional 6.5 days in the hospital and are five times more likely to be readmitted after discharge.
Increasing emphasis on personalized therapies
Personalized medicine aims to tailor healthcare to individual patients based on their genetic, molecular, and cellular profiles. To be effective, spatial genomics and transcriptomics are used to study gene activity in specific tissue regions, revealing heterogeneity within tissues. Spatial tools can map complex interactions between cells in different tissue regions, helping to pinpoint disease mechanisms and treatment targets in diseases like cancer, neurological disorders, and autoimmune diseases.
Complexity of data analysis
Spatial genomics and transcriptomics generate large, complex datasets that require specialized tools and expertise. Challenges include specialized knowledge requirements, lack of accessible tools, time-intensive learning curve, and resource constraints. Non-specialists, such as clinical practitioners or molecular biologists, struggle to integrate these technologies into their workflows. Accessible tools, often proprietary or open-source, require advanced coding skills, limiting usability for non-technical users. Additionally, smaller research labs may lack the budget or personnel to employ bioinformaticians or invest in training.
Continuous innovation in imaging, sequencing, and computational tools
Modern imaging technologies like super-resolution microscopy and light-sheet microscopy enable detailed visualization of gene expression and molecular interactions in tissues. Live-cell imaging provides dynamic insights into real-time cellular and molecular processes, enhancing translational research applications. Improved imaging tools attract new researchers and drive demand for spatial genomics technologies in areas like developmental biology, oncology, and neuroscience propelling the market growth.
Lack of standardized protocols and benchmarking
Spatial genomics and transcriptomics involve complex workflows like tissue preparation, imaging, sequencing, and data analysis. The absence of universal protocols can lead to inconsistencies in results. Sample preparation variability, such as tissue fixation methods, sectioning techniques, storage conditions, imaging and sequencing differences, and data analysis challenges, can result in varying gene expression profiles, spatial resolution, and data quality. Additionally, computational pipelines for data processing and interpretation can introduce biases, affecting the reliability of gene expression data.
Covid-19 Impact
The COVID-19 pandemic significantly impacted the Spatial Genomics & Transcriptomics Market, accelerating the adoption of advanced molecular technologies for understanding viral mechanisms and host responses. Researchers utilized spatial genomics to explore SARS-CoV-2 interactions with human tissues, fueling demand for cutting-edge tools. However, the pandemic also led to disruptions in supply chains. Despite these challenges, the urgency to study COVID-19 and other diseases has spurred innovations and investments, positively influencing the market's long-term growth prospects.
The carbon fiber segment is expected to be the largest during the forecast period
Over the forecasted timeframe, the autoclave processing segment is anticipated to be the largest market share owing to high-performance optical components like microscope stages, lenses, and supports, improving precision and stability in imaging systems, especially in spatial transcriptomics. Carbon fiber-integrated equipment offers better functionality and durability, making spatial genomics tools more efficient and attractive to researchers, potentially increasing adoption rates in labs, hospitals, and research institutions.
The autoclave processing segment is expected to have the highest CAGR during the forecast period
The autoclave processing segment is expected to have the highest CAGR growth during the estimation period autoclaving is crucial for sterilizing tissue samples and instruments that come into contact with genomic material, preventing contamination during spatial transcriptomics experiments. It also helps in tissue fixation by denaturing proteins and stabilizing tissues, preserving the spatial integrity of tissue sections, essential for accurate spatial gene expression studies. Both sterilization and tissue fixation are essential for efficient gene expression studies.
During the projected timeframe, the North America region is expected to hold the largest market share during the forecast period due to the advanced healthcare systems that enable the integration of spatial genomics into clinical practices, enabling precision medicine in oncology, neurology, and immunology. With the ability to adopt complex technologies and financial resources, North American hospitals and diagnostic centers are able to make personalized medicine a reality. Spatial genomics aids in biomarker discovery, drug development, and targeted therapies, particularly for complex diseases like cancer and neurological disorders.
The Asia Pacific region is predicted to witness the highest CAGR growth rate throughout the forecast period owing to china, India, Japan, and South Korea investing heavily in genomic research, particularly for personalized medicine, cancer research, and infectious disease genomics. These nations are focusing on genomic sequencing, precision medicine, and spatial transcriptomics to understand disease biology at a tissue-specific level. Leading research centers in the APAC region, such as the beijing genomics institute, the institute of bioinformatics, and riken institute.
Key players in the market
Some of the key players in Spatial Genomics & Transcriptomics market include 10X Genomics, Inc., Akoya Biosciences, Inc., BioSpyder Technologies Inc., Bio-Techne Corporation, Dovetail Genomics, LLC, Fluidigm Corporation, Genomic Vision SA, Illumina, Inc., Lunaphore Technologies SA, Nanostring Technologies, Inc., Natera Inc., PerkinElmer Inc., Rarecyte, Inc., Resolve Biosciences, S2 Genomic, Seven Bridges Genomics, Singular Genomics System, Inc. and Veranome Biosystems LLC.
In November 2024, Illumina, Inc. announced that it will release TruSight(TM) Oncology 500 v2 (TSO 500 v2), a new version of its flagship cancer research assay to enable comprehensive genomic profiling (CGP). The assay is currently under development, with global release planned for mid-2025.
In October 2024, Illumina, Inc. unveiled its MiSeq(TM) i100 Series of sequencing systems, delivering unparalleled benchtop speed and simplicity to advance next-generation sequencing (NGS) for labs.
In January 2024, PerkinElmer announced that it has acquired Covaris, a leading developer of solutions to empower life science innovations. The merger will accelerate Covaris' growth potential and expand PerkinElmer's existing life sciences portfolio into the high-growth diagnostics end market.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.