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市场调查报告书
商品编码
1662731
2030 年 3D 生物列印人体组织市场预测:按技术、应用和地区进行的全球分析3D Bioprinted Human Tissue Market Forecasts to 2030 - Global Analysis By Technology, Application and By Geography |
根据 Stratistics MRC 的数据,全球 3D 生物列印人体组织市场预计在 2024 年将达到 25.9 亿美元,到 2030 年将达到 46.7 亿美元,预测期内的复合年增长率为 10.3%。
3D 生物列印人体组织是再生医学和生物医学研究领域的突破性进展。该技术使用生物墨水(活细胞、生物材料和生长因子的混合物)逐层创建组织结构。这些工程组织在结构、功能和生物特性上与天然人体组织非常相似,因此对于测试药物、模拟疾病和了解细胞间相互作用非常有用。此外,目前正在研究将这项创新扩展到临床应用,例如生产针对特定患者的移植物和用于移植的整个器官,以解决捐赠组织的严重短缺问题。
根据《机械工程前沿》杂誌发表的一篇评论,“3D生物列印是增材製造的一种扩展应用,它采用自上而下的方法逐层构建复杂组织,目前正在探索其在组织工程和再生医学中的应用。”
个人化治疗兴趣日益浓厚
随着医疗专业人士寻求客製化治疗方案来满足每位患者的需求,个人化医疗领域正在不断增长。透过 3D 生物列印组织实现的患者特定组织模型的开发可以实现更准确的药物测试和疾病建模。这些模型可以透过模拟不同患者对特定治疗的反应来提高治疗效果并减少副作用。此外,临床和研究环境中对 3D 生物列印组织的需求受到列印与患者基因匹配的组织的能力的推动,为精准医疗创造了新的可能性。
昂贵的生物列印材料和设备
阻碍 3D 生物列印技术市场发展的主要障碍之一仍然是其成本。列印人体组织所需的专用生物印表机价值可达数十万美元。此外,列印过程中使用的生物墨水价格昂贵,并且必须与活细胞相容并适合组织生长。这些成本使得没有资金投资该技术的中小型企业和学术机构无法使用3D生物列印。此外,高昂的前期成本限制了生物列印组织的广泛应用,尤其是在开发中国家,阻碍了其可扩展性。
个性化医疗的发展
3D生物列印将在快速发展的个人化医疗领域中发挥关键作用。透过创建适合每个患者基因组成的组织,医生可以提高器官移植和其他治疗的成功率。透过使用生物列印组织来模拟患者的疾病或遗传状况,医生可以在将药物给予患者之前在这种客製化组织上测试药物。这提高了治疗的准确性,减少了实验室测试所花费的时间,并有助于防止副作用。此外,对于目前难以治疗的疾病,例如罕见疾病或遗传疾病,可以透过个人化组织列印开发更有效的治疗方法。
监管障碍和待核准
漫长而复杂的监管过程是3D生物列印产业面临的最大风险之一,尤其是在医疗领域。使用活细胞 3D 生物列印组织和器官引发了许多伦理和监管问题。在生物列印组织核准用于人类患者之前,必须通过严格的测试以确保安全性、有效性和符合道德准则。许多国家对此的监管路径仍不明确,这给开发生物列印技术的公司带来了不确定性。此外,冗长的医疗用途监管核准流程可能会延迟我们进入市场并限制我们快速扩展业务的能力。
3D 生物列印人体组织市场受到了 COVID-19 疫情的多方面影响。一方面,疫情阻碍了研发活动,减缓了生物列印技术的进展。由于製造设施和实验室暂时关闭,许多公司的临床测试和製造流程都出现延迟。然而,这场大流行也凸显了器官移植、组织工程和传统药物测试替代方案的需求,并引发了人们对 3D 生物列印人体组织用于疾病建模、药物发现和疫苗开发的兴趣。
喷墨生物列印市场预计将在预测期内占据最大份额
预计喷墨生物列印领域将在预测期内占据最大的市场占有率,因为它在创建高解析度组织结构方面具有出色的精度和准确度。透过使用基于液滴的沉积来放置细胞和生物材料,该技术可以创建复杂的组织结构。由于其经济实惠、可扩展和适应性,喷墨生物列印在组织工程、个人化医疗和药物测试等应用领域备受青睐。此外,喷墨生物列印在 3D 生物列印行业中占据主导地位,这是由于其在使用生物墨水方面的多功能性以及在医学研究应用中的良好记录。
预计药物测试和开发部门将在预测期内实现最高的复合年增长率。
预计药物测试和开发部门在预测期内将呈现最高的成长率。这个市场是由对先进药物测试平台日益增长的需求所驱动,这些平台比传统模型更接近人体组织的反应。利用 3D 生物列印组织,製药公司可以开发出更精确、更有效的药物,提供比动物试验更可靠、更符合道德的替代方案。此外,这些组织模式还能实现个人化医疗策略,降低开发成本并加速新药上市。
预计预测期内北美地区将占据最大的市场占有率。这是由于对尖端生物技术研究的大量投入、主要市场参与企业的强大影响力以及 3D 生物列印技术在组织工程和药物测试等各个行业的日益广泛的应用所推动。此外,成熟的医疗保健基础设施、鼓励医疗创新的政府计划以及顶尖学术和研究机构的存在进一步推动了该地区市场的成长。美国作为生物列印创新的中心尤其引人注目,促进了3D生物列印组织应用的快速商业化。
预计亚太地区在预测期内将呈现最高的复合年增长率。该地区的生物技术正在快速进步,并且正在不断推出提高医学研究和医疗保健能力的倡议。这一增长主要得益于中国、日本和印度等国家製药和生物技术产业的扩张以及医疗保健基础设施投资的增加。此外,个人化医疗和更好的药物检测技术日益增长的需求也推动了3D生物列印技术的采用,有助于该地区市场的强劲扩张。
According to Stratistics MRC, the Global 3D Bioprinted Human Tissue Market is accounted for $2.59 billion in 2024 and is expected to reach $4.67 billion by 2030 growing at a CAGR of 10.3% during the forecast period. 3D bioprinted human tissue is a revolutionary development in regenerative medicine and biomedical research. This technique uses bioinks-mixtures of living cells, biomaterials, and growth factors-to create tissue constructs layer by layer. These engineered tissues are very useful for testing drugs, simulating diseases, and understanding how cells interact with each other because they are very similar to natural human tissues in terms of structure, function, and biology. Additionally, in order to address the severe lack of donor tissues, research is being conducted to scale this innovation for clinical applications, such as producing patient-specific grafts or even entire organs for transplantation.
According to a review in Frontiers in Mechanical Engineering, "3D bioprinting, which is an extended application of additive manufacturing, is now being explored for tissue engineering and regenerative medicine as it involves the top-down approach of building the complex tissue in a layer-by-layer fashion".
Growing interest in customized treatment
The field of personalized medicine is expanding as medical practitioners seek to customize care to each patient's unique needs. Drug testing and disease modeling can be done more accurately owing to the development of patient-specific tissue models made possible by 3D bioprinted tissues. These models can be used to improve therapeutic efficacy and reduce side effects by simulating how various patients will react to particular treatments. Moreover, the demand for 3D bioprinted tissues in clinical and research settings is being driven by the capacity to print tissues that are genetically matched to patient profiles, which creates new possibilities for precision medicine.
Expensive bioprinting supplies and equipment
One major barrier to the market for 3D bioprinting technology is still its cost. The cost of the specialized bioprinters needed to print human tissues can reach hundreds of thousands of dollars. Furthermore, the bioinks used in the printing process are expensive and need to be compatible with living cells and made for tissue growth. Smaller businesses or academic institutions that might not have the funds to invest in this technology find 3D bioprinting less accessible due to these costs. Furthermore, the high initial costs restrict the widespread use of bioprinted tissue, particularly in developing nations, and impede its scalability.
Development in tailored healthcare
3D bioprinting is positioned to be a key component of the quickly expanding field of personalized medicine. Doctors may be able to increase the success rates of organ transplants and medical treatments by producing tissues that are specifically suited to each patient's genetic composition. Physicians could test medications on these customized tissues before giving them to patients by using bioprinted tissues to simulate a patient's illness or genetic condition. This would improve the accuracy of medical treatments, decrease the amount of time spent in clinical trials, and help prevent adverse reactions. Additionally, more effective treatments for diseases that is currently hard to treat, like rare diseases and genetic disorders, may be developed as a result of personalized tissue printing.
Regulatory obstacles and approval hold-ups
The lengthy and intricate regulatory process is one of the biggest risks facing the 3D bioprinting industry, especially in the medical sector. Using living cells to create 3D bioprinted tissues and organs raises a number of ethical and regulatory issues. Bioprinted tissues must pass stringent testing to guarantee they adhere to safety, effectiveness, and ethical guidelines before being approved for use in human patients. These regulatory pathways are still unclear in many nations, which cause uncertainty for businesses creating bioprinting technologies. Moreover, slow regulatory approval processes for medical applications can postpone market entry and limit the possibility of quick expansion.
The market for 3D bioprinted human tissue was affected by the COVID-19 pandemic in a variety of ways. On the one hand, the pandemic slowed down the advancement of bioprinting technologies by interfering with research and development activities because of lockdowns, travel restrictions, and resource reallocation to fight the virus. Due to the temporary closure of manufacturing facilities and laboratories, many businesses experienced delays in their clinical trials and production processes. However, the pandemic highlighted the need for alternatives to organ transplantation, tissue engineering, and conventional drug testing, which sparked interest in 3D bioprinted human tissues for disease modeling, drug discovery, and vaccine development.
The Inkjet Bioprinting segment is expected to be the largest during the forecast period
The Inkjet Bioprinting segment is expected to account for the largest market share during the forecast period because of its exceptional precision and accuracy in creating high-resolution tissue structures. By placing cells and biomaterials using droplet-based deposition, this technology makes it possible to create intricate tissue structures. Because of its affordability, scalability, and adaptability, inkjet bioprinting is highly preferred for uses such as tissue engineering, personalized medicine, and drug testing. Moreover, its dominance in the 3D bioprinting industry is a result of its versatility in working with bioinks and its proven track record in medical and research applications.
The Drug Testing and Development segment is expected to have the highest CAGR during the forecast period
Over the forecast period, the Drug Testing and Development segment is predicted to witness the highest growth rate. The growing need for sophisticated drug testing platforms that more closely resemble human tissue responses than conventional models is driving this market. Pharmaceutical companies can create medications with greater accuracy and effectiveness by using 3D bioprinted tissues, which provide a more dependable and moral substitute for animal testing. Additionally, these tissue models also enable personalized medicine strategies, which lower development costs and expedite the release of new medications.
During the forecast period, the North America region is expected to hold the largest market share, propelled by substantial expenditures in cutting-edge biotechnology research, a robust presence of important industry participants, and the expanding use of 3D bioprinting technologies across a range of industries, including tissue engineering and drug testing. Furthermore, the region's market growth is further fuelled by established healthcare infrastructures, government programs that encourage medical innovation, and the presence of top academic and research institutions. As a center for bioprinting innovations, the United States stands out in particular, promoting the quick commercialization of 3D bioprinted tissue applications.
Over the forecast period, the Asia Pacific region is anticipated to exhibit the highest CAGR. Rapid biotechnology advancements and a growing number of initiatives to improve medical research and healthcare capabilities are occurring in the region. Growing pharmaceutical and biotechnology industries in nations like China, Japan, and India, as well as rising investments in healthcare infrastructure, are major forces behind this growth. Moreover, the adoption of 3D bioprinting technologies is also being fuelled by the growing need for personalized medicine and better drug testing techniques, which is helping to drive the region's robust market expansion.
Key players in the market
Some of the key players in 3D Bioprinted Human Tissue market include 3D Systems, Inc., General Electric, Organovo Holdings, Inc., Vivax Bio, LLC, The Pexion Group, Materialise NV, EnvisionTEC, Inc., Stratasys Ltd., Oceanz 3D printing Inc, Prellis Biologics Inc, SOLS Systems Inc and Inventia Life Science PTY Ltd.
In June 2024, 3D Systems announced the signing of a multi-year purchase agreement, with a value estimated to approach a quarter-billion dollars through 2028, in support of the indirect manufacturing process for clear aligners. The contract builds upon the exceptional legacy the Company has established as a key supplier of 3D printing technology to the clear aligner industry.
In June 2024, Stratasys Ltd. and Aviation manufacturing pioneer AM Craft announced that they are partnering to align the two companies' efforts to grow the demand for flight-certified 3D printed parts in the aviation industry. The companies signed a definitive commercial collaboration agreement, along with Stratasys' strategic investment in AM Craft.
In January 2022, Prellis Biologics, Inc. (Prellis) announced that it has entered into multi-target drug discovery collaboration and licensing agreement with Bristol Myers Squibb utilizing Prellis Biologics' first-in-class externalized human immune system (EXIS(TM)) based on human lymph node organoids (LNO(TM)).