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市场调查报告书
商品编码
1725148
2032 年尿激酶市场预测:按类型、来源、给药途径、应用、最终用户和地区进行的全球分析Urokinase Market Forecasts to 2032 - Global Analysis By Type (Urokinase Powder and Urokinase Solution), Source, Route of Administration, Application, End User and By Geography |
根据 Stratistics MRC 的数据,全球尿激酶市场预计在 2025 年达到 20.8 亿美元,到 2032 年将达到 35 亿美元,预测期内的复合年增长率为 7.7%。
尿激酶是一种血栓溶解酶,医学上用于溶解体内的血栓。它是丝胺酸蛋白酶,最初来自人类尿液,但现在通常使用重组 DNA 技术生产。尿激酶将胞浆素原原转化为胞浆素,并作为分解纤维蛋白(血块的主要蛋白质组成)的酶。主要用于治疗肺动脉栓塞、深层静脉栓塞症、导管阻塞等。尿激酶作为纤溶酶原激活剂,在恢復阻塞血管的血流中起着重要作用,使其成为急诊和介入医学的重要治疗选择。
根据英国心臟基金会 2024 年的一篇报导,英国有 760 万人患有心臟和循环系统疾病。
血栓性疾病盛行率不断上升
由于对血栓溶解疗法的需求增加,血栓疾病的盛行率不断上升,推动了尿激酶市场的发展。尿激酶用于分解血栓,在治疗肺动脉栓塞、深层静脉栓塞症和急性心肌梗塞中发挥重要作用。随着这些疾病在全球范围内的盛行率上升,特别是在老年人口中,对有效的溶栓疗法的需求也日益增加。这一趋势有利于尿激酶市场并刺激其生产和应用的进一步发展。
医疗费用高昂
高昂的治疗费用严重阻碍了尿激酶市场的成长,因为它限制了患者和医疗保健提供者获得治疗的机会,尤其是在中低收入地区。如此高的治疗费用限制了尿激酶治疗方法的广泛使用,并导致对更便宜的替代疗法的需求。此外,高成本对医疗预算造成压力,阻碍了保险覆盖,并限制了广泛的临床使用,最终减缓了市场扩张并抑制了溶栓疗法的创新。
药物传输技术进步
药物输送系统的技术进步对尿激酶市场产生了重大影响,提高了其治疗效果和精确度。靶向输送机制和基于奈米粒子的配方等技术创新有望提高生物有效性并减少副作用。这些进步提高了药物针对特定部位的能力,优化了血栓和心臟病等疾病的治疗。此外,控制释放技术和个人化药物传递系统有助于改善患者的治疗效果,进而推动尿激酶市场的需求和成长。
出血併发症的风险
出血併发症的风险将严重阻碍尿激酶市场的成长。尿激酶是一种溶栓剂,极有可能引起内出血,尤其是对于有潜在疾病或服用抗凝血剂的患者。这些安全问题限制了医疗保健提供者对尿激酶的采用,并促使谨慎开药。此外,监管限制和更安全替代药物的可用性进一步限制了市场扩张,对需求和整体市场表现产生负面影响。
COVID-19的影响
COVID-19 疫情严重扰乱了尿激酶市场,导致择期手术延迟、住院人数减少以及供应链中断。在疫情高峰期,对非新冠相关治疗(包括尿激酶等溶栓药物)的需求下降。然而,随着医疗保健系统的稳定和外科手术的恢復,市场开始復苏。此外,人们对 COVID-19 患者血栓併发症的认识提高间接支持了对抗凝血和溶栓疗法的需求。
预计尿激酶溶液细分市场在预测期内将占据最大份额
预计在预测期内,尿激酶溶液部分将占据最大的市场占有率。尿激酶溶液,尤其是静脉注射和局部形式,因其能够快速溶解血栓,改善肺动脉栓塞和深层静脉栓塞症等患者的预后而受到青睐。医院和医疗机构越来越多地采用尿激酶製剂以及正在进行的研究也对该领域的市场扩张产生了积极影响。
预计深层静脉栓塞症领域在预测期内将以最高复合年增长率成长
由于血栓性疾病盛行率的上升以及对早期诊断和治疗的认识的提高,预计深层静脉栓塞症部分将在预测期内出现最高增长率。尿激酶是一种溶栓剂,广泛用于深部静脉栓塞(DVT)患者的溶栓治疗,其需求日益增长。医疗基础设施的进步和人口老化也促进了市场扩张。这一趋势使 DVT 成为尿激酶市场持续成长和创新的关键驱动力。
预计亚太地区将在预测期内占据最大的市场占有率。这是由于心血管疾病的增加、认识的提高以及获得先进治疗的机会的改善推动了需求。这种成长正在刺激创新、鼓励投资并改善开发中国家患者的治疗效果。此外,政府支持和不断扩大的医疗保健基础设施正在加速市场渗透,使挽救生命的溶栓疗法更容易获得,最终有助于改善公共卫生并增强当地製药业的前景。
在预测期内,由于人们对溶栓疗法的认识不断提高,预计北美将呈现最高的复合年增长率。医疗保健基础设施的进步、大型製药公司的存在以及支持性法律规范进一步推动了市场扩张。老年人口的增长和对微创治疗的需求将推动基于尿激酶的疗法的采用。这些因素的结合显着改善了患者的治疗效果,刺激了区域市场的成长和创新。
According to Stratistics MRC, the Global Urokinase Market is accounted for $2.08 billion in 2025 and is expected to reach $3.50 billion by 2032 growing at a CAGR of 7.7% during the forecast period. Urokinase is a thrombolytic enzyme used medically to dissolve blood clots in the body. It is a serine protease originally derived from human urine, but now commonly produced using recombinant DNA technology. Urokinase works by converting plasminogen to plasmin, an enzyme that breaks down fibrin, the primary protein component of blood clots. It is primarily used to treat conditions such as pulmonary embolism, deep vein thrombosis, and catheter blockages. As a fibrinolytic agent, urokinase plays a vital role in restoring blood flow in occluded vessels, making it a critical therapeutic option in emergency and interventional medicine.
According to 2024 article by British Heart Foundation, 7.6 million people are living in with heart and circulatory disease in UK.
Rising Prevalence of Thrombotic Disorders
The growing incidence of thrombotic disorders is propelling the urokinase market due to the heightened need for thrombolytic treatments. The enzyme urokinase, which is employed to break down blood clots, plays a vital role in the treatment of conditions like pulmonary embolism, deep vein thrombosis, and acute myocardial infarction. As the global prevalence of these disorders rises, particularly among aging populations, the demand for effective clot-dissolving treatments is increasing. This trend is benefiting the urokinase market and spurring further developments in its production and application.
High Treatment Costs
High treatment costs significantly hinder the growth of the urokinase market by limiting accessibility for patients and healthcare providers, particularly in low- and middle-income regions. These elevated expenses reduce the adoption of urokinase-based therapies, as more affordable alternatives are sought. Additionally, high costs strain healthcare budgets, discourage insurance coverage, and restrict widespread clinical use, ultimately slowing market expansion and impeding innovation in thrombolytic treatments.
Technological Advancements in Drug Delivery
Technological advancements in drug delivery systems have significantly impacted the Urokinase market by enhancing its therapeutic efficacy and precision. Innovations such as targeted delivery mechanisms and nanoparticle-based formulations ensure better bioavailability and reduced side effects. These advancements improve the drug's ability to target specific sites, optimizing the treatment of conditions like blood clots and heart attacks. Additionally, controlled release technologies and personalized drug delivery systems contribute to improved patient outcomes, driving demand and growth within the Urokinase market.
Risk of Bleeding Complications
The risk of bleeding complications significantly hinders the growth of the urokinase market. Urokinase, a thrombolytic agent, carries a high potential for causing internal bleeding, particularly in patients with underlying conditions or on anticoagulants. This safety concern limits its widespread adoption among healthcare providers, prompting cautious prescription practices. Additionally, regulatory restrictions and the availability of safer alternatives further restrain market expansion, negatively impacting demand and overall market performance.
Covid-19 Impact
The COVID-19 pandemic significantly disrupted the urokinase market due to delays in elective surgeries, reduced hospital admissions, and supply chain interruptions. Demand for non-COVID-related therapies, including thrombolytic agents like urokinase, declined during the peak of the pandemic. However, as healthcare systems stabilized and surgical procedures resumed, the market began recovering. Additionally, increased awareness of thrombotic complications in COVID-19 patients indirectly supported demand for anticoagulant and thrombolytic therapies.
The urokinase solution segment is expected to be the largest during the forecast period
The urokinase solution segment is expected to account for the largest market share during the forecast period because Urokinase solutions, particularly in intravenous and local delivery forms, are gaining preference due to their ability to rapidly dissolve blood clots, improving patient outcomes in conditions like pulmonary embolism and deep vein thrombosis. The growing adoption of urokinase solutions in hospitals and healthcare facilities, combined with ongoing research, is further fueling the segment's positive impact on market expansion.
The deep vein thrombosis segment is expected to have the highest CAGR during the forecast period
Over the forecast period, the deep vein thrombosis segment is predicted to witness the highest growth rate, due to the rising incidence of thrombotic disorders and increased awareness of early diagnosis and treatment. Urokinase, a thrombolytic agent, is widely used to dissolve blood clots in DVT patients, leading to its growing demand. Advancements in healthcare infrastructure and an aging population further contribute to market expansion. This trend positions DVT as a key driver fueling sustained growth and innovation in the urokinase market.
During the forecast period, the Asia Pacific region is expected to hold the largest market share due to rising cardiovascular cases, increased awareness, and improved access to advanced therapies are driving demand. This growth is fostering innovation, encouraging investments, and improving patient outcomes across developing nations. Additionally, government support and expanding healthcare infrastructure are accelerating market penetration, making life-saving thrombolytic therapies more accessible, ultimately contributing to better public health and a stronger regional pharmaceutical landscape.
Over the forecast period, the North America region is anticipated to exhibit the highest CAGR, owing to increasing awareness of thrombolytic therapies. Advancements in healthcare infrastructure, strong presence of key pharmaceutical players, and supportive regulatory frameworks further fuel market expansion. The growing geriatric population and demand for minimally invasive procedures enhance the uptake of urokinase-based treatments. Collectively, these factors are significantly improving patient outcomes and driving the regional market's growth and innovation.
Key players in the market
Some of the key players profiled in the Urokinase Market include Syner-Med Ltd., Microbix Biosystems Inc., Wuxi Green Pharmaceutical Co., Ltd., Jiangxi Haoran Bio-Pharma Co., Ltd., Medicure Inc., Lee's Pharmaceutical Holdings Ltd., Taj Pharmaceuticals Limited, Jiangsu Techpool Bio-Pharma Co., Ltd., Guangzhou Recomgen Biotech Co., Ltd., LGM Pharma, ScienCell Research Laboratories, Inc., BioVision, Inc., Abbott Laboratories, Enzo Life Sciences, Inc., Molecular Innovations, Inc., Prospec-Tany Technogene Ltd., Wuhan YZY Biopharma Co., Ltd., GenScript Biotech Corporation and Chymotech AS.
In August 2024, Abbott and Medtronic announced a significant global partnership, to integrate Abbott's FreeStyle Libre continuous glucose monitoring (CGM) technology with Medtronic's insulin delivery systems. This collaboration aims to enhance diabetes management by enabling automatic insulin adjustments based on real-time glucose data.
In June 2024, Abbott has partnered with the National Association of Community Health Centers (NACHC) to improve access to nutritious food and health services. The collaboration aims to enhance healthcare delivery and address the growing health challenges related to nutrition in underserved communities.