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市场调查报告书
商品编码
1766100
长读定序市场:2032 年未来预测-依产品、技术、应用、最终使用者和地区进行分析Long Read Sequencing Market Forecasts to 2032 - Global Analysis By Product, Technology (Single-Molecule Real-Time Sequencing, Nanopore Sequencing, Synthetic Long-Read Sequencing and Other Technologies), Application, End User and By Geography |
根据 Stratistics MRC 的数据,全球长读定序市场预计在 2025 年将达到 13.2 亿美元,到 2032 年将达到 58.7 亿美元,预测期内的复合年增长率为 23.7%。
一种被称为「长读定序」的技术可以创建长而连续的DNA链读取,通常长度为数千到数百万个碱基对。与传统的短读技术相比,它可以更精确地定位包含结构变异、重复序列和全长转录物的复杂基因组区域。牛津奈米孔平台和太平洋生物科学公司的SMRT等技术使即时定序和极简样品製备成为可能。长读定序是基因组学研究中的强大工具,因为它透过提供遗传资讯的背景和连续性来改善基因组组装、临床诊断和演化研究。
精确基因组组装的需求不断增加
复杂的基因组区域难以透过短读长定序方法解析,但长读长定序方法使其成为可能。它可以更精确地检测大片段插入和缺失、重复序列以及结构变异。个人化医疗、疾病研究和演化研究等领域的应用都依赖这种准确性。随着学术界和医疗相关人员越来越重视准确且全面的基因数据,长读长平台正变得越来越受欢迎。为了满足日益增长的需求,业内公司正在投资先进的定序系统。
高成本、错误率高
由于技术要求高,需要昂贵的设备和化学品,限制了它们在小型实验室中的应用。由于每个样本的定序成本高昂,它们在更广泛的临床和科研环境中的应用也受到限制。此外,长读长定序输出的错误率会影响资料的准确性和可靠性。这通常需要对短读长进行额外的定序以进行检验,这既昂贵又耗时。因此,用户不愿完全迁移到长读长平台,限制了市场扩张。
扩大在临床诊断和个人化医疗的应用
长读长定序可以精确检测基因融合、复杂的基因组区域以及短读长定序经常忽略的结构变化。这种精准度对于诊断复杂疾病和罕见基因异常至关重要。它能够根据每位患者独特的基因组成客製化治疗方案,从而实现个人化医疗。此外,该技术还有助于癌症基因组分析和非侵入性产前检测。随着精准医疗和客製化医疗需求的日益增长,长读长定序正日益普及。
来自短读技术和新兴定序平台的竞争
短读长方法易于采用,具有成熟且广泛可用的基础设施和用户友好的方法。由于其高准确度和高通量,短读长方法在许多临床和研究应用中仍然被广泛使用。新的平台正在弥补读长的差距,同时又不牺牲价格。长读长供应商面临创新和快速降价的压力。因此,市场扩张面临缓慢的采用和日益激烈的价格竞争。
COVID-19的影响
COVID-19 疫情加速了基因组学研究和诊断方法的开发,对长读长定序市场产生了积极影响。精准快速病原体检测的需求日益增长,刺激了对定序技术的投资。长读长定序在研究病毒突变、改进监测和辅助疫苗研发方面发挥了关键作用。此外,政府与生技公司之间的合作也扩大了全球定序能力。儘管最初供应链中断,但由于人们对基因组学工具在医疗准备和回应方面的认识不断提高,市场实现了显着增长。
预计在预测期内,消耗品部分将成长至最大的部分。
由于每次定序运作都有固定的需求,预计耗材领域将在预测期内占据最大的市场占有率。耗材包括试剂、套件和流动槽,这些对于准确且有效率地产生长读长数据至关重要。耗材技术的进步提高了读取长度、准确性和吞吐量,吸引了更多的研究和临床应用。基因组学和肿瘤学等领域对长读长定序的日益普及,推动了对高性能耗材的需求。这种稳定成长的需求将增强整体市场的成长和盈利。
预计在预测期内,医院和医疗保健提供者部门将以最高的复合年增长率成长。
由于患者诊断和个人化治疗对准确且全面的基因组数据的需求不断增长,预计医院和医疗保健提供者领域将在预测期内实现最高增长。这些机构越来越多地采用长读长定序来识别短读长方法可能遗漏的复杂基因突变。罕见遗传疾病和癌症的增加进一步推动了临床环境中对准确基因组分析的需求。将长读长定序技术整合到医院实验室可以改善诊断工作流程并提升病患预后。此外,政府资助和官民合作关係正在推动先进测序技术在医疗保健基础设施中的应用。
在预测期内,亚太地区预计将占据最大的市场占有率,这得益于基因组研究投入的增加、政府对精准医疗的支持以及遗传疾病盛行率的上升。中国、日本和印度等国家正在扩大其生物技术基础设施和研究能力。当地大学与全球生物技术公司之间的合作正在促进技术的采用。此外,个人化医疗需求的不断增长以及人们对基因组检测的认识不断提高,也全部区域的市场扩张做出了重大贡献。
预计北美地区在预测期内的复合年增长率最高,这得益于该地区拥有领先的企业、先进的医疗基础设施以及高额的研发支出。尤其是美国,它在尖端基因组技术在临床和研究应用方面的应用方面处于领先地位。该地区受益于完善的资金筹措架构、健全的监管制度以及广泛的产学合作。与亚太地区不同,北美市场成熟,能够快速部署创新的群体定序平台和大规模的群体基因组学计画。
According to Stratistics MRC, the Global Long Read Sequencing Market is accounted for $1.32 billion in 2025 and is expected to reach $5.87 billion by 2032 growing at a CAGR of 23.7% during the forecast period. The technique known as "long read sequencing" creates lengthy, continuous reads of DNA strands, usually ranging in length from thousands to millions of base pairs. It enables more precise mapping of intricate genomic areas, including structural variations, repetitive sequences, and full-length transcripts, in contrast to conventional short-read techniques. Real-time sequencing and minimal sample preparation are made possible by technologies such as Oxford Nanopore's platforms and Pacific Biosciences' SMRT. Long read sequencing is a potent tool in genomics research because it improves genome assembly, clinical diagnostics, and evolutionary studies by giving genetic information more context and continuity.
Increasing demand for accurate genome assembly
Complex genomic areas are challenging to resolve with short reads, but long read sequencing methods make this possible. They provide more precision in detecting big insertions or deletions, repetitive sequences, and structural alterations. Applications in personalised treatment, disease research, and evolutionary studies all depend on this accuracy. Long read platforms are becoming more and more popular as academics and medical professionals place a higher value on accurate and comprehensive genetic data. In order to satisfy this rising demand, industry participants are investing in sophisticated sequencing systems.
High cost and error rates
The sophisticated technology required necessitates costly equipment and chemicals, which limits small labs' access to it. Its use in extensive clinical and scientific settings is restricted by the high expense of sequencing each sample. Furthermore, the correctness and dependability of data are jeopardised by the error rates in long-read outputs. This frequently calls for additional short-read sequencing for validation, which raises the expense and time. As a result, users hesitate to fully transition to long-read platforms, slowing market expansion.
Growing use in clinical diagnostics and personalized medicine
Gene fusions, complicated genomic areas, and structural changes that short reads frequently overlook can be accurately detected by long read sequencing. For the diagnosis of complex diseases and rare genetic abnormalities, this accuracy is essential. This helps personalised medicine by customising care according to each patient's distinct genetic composition. Additionally, the technology helps cancer genomics and non-invasive prenatal diagnostics. Long read sequencing is gaining traction as the need for accurate, customised healthcare increases.
Competition from short read technologies and emerging sequencing platforms
Adoption is facilitated by the established, widely used infrastructure and user familiarity of short read methods. Because of its precision and high throughput, short reads are still used in many clinical and research applications. New platforms are bridging the read-length divide without sacrificing price. Long read suppliers are under pressure to innovate and cut prices quickly as a result. Market expansion is therefore confronted with slower adoption and more intense pricing competition.
Covid-19 Impact
The COVID-19 pandemic positively impacted the Long Read Sequencing market by accelerating genomic research and diagnostic development. Increased demand for accurate and rapid pathogen detection drove investments in sequencing technologies. Long read sequencing played a vital role in studying virus mutations, improving surveillance, and supporting vaccine development. Additionally, collaborative efforts between governments and biotech firms expanded sequencing capacity globally. Despite initial supply chain disruptions, the market experienced significant growth due to heightened awareness of genomic tools in healthcare preparedness and response.
The consumables segment is expected to be the largest during the forecast period
The consumables segment is expected to account for the largest market share during the forecast period, due to ensured recurring demand through each sequencing run. These include reagents, kits, and flow cells, which are essential for accurate and efficient long-read data generation. Technological advancements in consumables enhance read length, accuracy, and throughput, attracting more research and clinical applications. As the adoption of long-read sequencing grows in fields like genomics and oncology, the need for high-performance consumables rises. This steady and expanding demand strengthens the overall market growth and profitability.
The hospitals & healthcare providers segment is expected to have the highest CAGR during the forecast period
Over the forecast period, the hospitals & healthcare providers segment is predicted to witness the highest growth rate, due to the growing demand for accurate and comprehensive genomic data for patient diagnostics and personalized treatment. These institutions increasingly adopt long read sequencing to identify complex genetic variations that short read methods may miss. Rising incidences of rare genetic disorders and cancer further drive the need for precise genomic analysis in clinical settings. Integration of long read sequencing into hospital labs improves diagnostic workflows and enhances patient outcomes. Additionally, government funding and public-private partnerships support the adoption of advanced sequencing technologies in healthcare infrastructure.
During the forecast period, the Asia Pacific region is expected to hold the largest market share due to increasing investments in genomics research, government support for precision medicine, and the rising prevalence of genetic disorders. Countries like China, Japan, and India are expanding their biotechnology infrastructure and research capabilities. Collaborations between local universities and global biotech firms are fuelling technological adoption. Moreover, the growing demand for personalized healthcare and increasing awareness about genomic testing contribute significantly to market expansion across the region.
Over the forecast period, the North America region is anticipated to exhibit the highest CAGR, owing to the presence of major players, advanced healthcare infrastructure, and high R&D expenditure. The U.S., in particular, leads in the adoption of cutting-edge genomic technologies for clinical and research applications. The region benefits from established funding frameworks, robust regulatory systems, and widespread academic-industry collaborations. Unlike Asia Pacific, North America's market maturity allows for rapid deployment of innovative sequencing platforms and large-scale population genomics initiatives.
Key players in the market
Some of the key players profiled in the Long Read Sequencing Market include Pacific Biosciences, Oxford Nanopore Technologies, Illumina Inc., BGI Genomics, MGI Tech, 10x Genomics, Agilent Technologies, Thermo Fisher Scientific, Qiagen, Bionano Genomics, Element Biosciences, Quantapore Inc., Universal Sequencing Technology, BaseClear BV, Cantata Bio, LLC, Future Genomics Technologies B.V., MicrobesNG and SeqLL, Inc.
In May 2025, PacBio expanded its distribution agreement with Xi'an-based Haorui Gene, making Haorui the distributor for the Vega benchtop system across China and providing product support. Haorui had already deployed 10 Sequel II and Revio sequencers, focusing on blood typing genomics and HLA testing.
In October 2024, PacBio signed a research collaboration agreement to accelerate cancer genomics research in Asia, leveraging both its long-read (Revio) and short-read (Onso) sequencing platforms. The collaboration, supported by DKSH, aims to expand multi-omics research and precision oncology in the region.
In July 2024, Oxford Nanopore and Plasmidsaurus entered an expanded, multi-year strategic collaboration to transform the plasmid sequencing market using nanopore technology. This partnership aims to deliver rapid, high-quality, and cost-effective whole-plasmid sequencing, with plans to co-develop new technologies and applications for microbial and gene therapy use cases.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.