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市场调查报告书
商品编码
1833575
2032年肠外抗生素市场预测:按药物类别、活性频谱、剂型、给药途径、适应症、最终用户和地区进行的全球分析Parenteral Antibiotics Market Forecasts to 2032 - Global Analysis By Drug Class, Spectrum of Activity, Formulation Type, Route of Administration, Indication, End User and By Geography |
根据 Stratistics MRC 的数据,全球肠外抗生素市场预计在 2025 年达到 257.4 亿美元,到 2032 年将达到 394.8 亿美元,预测期内的复合年增长率为 6.3%。
肠外抗生素是指在消化器官系统外给药的药物,通常透过静脉注射、肌肉注射或皮下注射。它们适用于紧急治疗以及无法口服或胃肠道吸收不足的情况。这种方法将药物直接输送到血液中,从而具有更快的起效速度、更高的生物利用度,并能有效感染疾病需要即时干预的严重或广泛性感染疾病。
根据尼泊尔国家生物技术资讯中心 (NCBI) 2021 年 11 月发表的一项研究,2019 年尼泊尔肠外抗生素的总限定日剂量 (DDD) 达到 48,947.7,比 2017 年的 39,639.7 增长了 23%。
抗生素抗药性(AMR)的蔓延
随着病原体不断进化并对传统疗法产生抗药性,医疗保健提供者正转向注射剂以获得更快、更有效的治疗效果。这一趋势在医院环境中尤其明显,因为医院环境中存在多重抗药性感染。药物输送系统和製剂科学的技术进步正在提高肠外抗生素的有效性。精准医疗和特异性病原体的治疗的兴起进一步推动了市场成长。全球卫生组织也将降低抗生素抗药性作为优先事项,并推动对新型抗生素和管理计画的投资。
开发和商业化成本高
大规模临床试验、严格的安全规程以及遵守FDA和EMA法规等全球标准,导致开发週期更长、成本更高。脂质体和缓释性等先进技术的采用,也让核准流程更加复杂。规模较小的製药公司往往面临资源限制,这限制了其创新和扩大生产规模的能力。此外,低温运输物流和无菌包装的需求也增加了营运成本。这些因素共同阻碍了药物快速进入市场,并减缓了治疗方法创新的步伐。
扩大门诊肠外抗生素治疗(OPAT)
门诊肠外抗生素治疗 (OPAT) 的推广为市场开闢了新的成长途径。 OPAT 允许患者在院外接受抗生素输注,从而减轻住院负担和医疗费用。携带式输注设备和远端监控技术的进步使 OPAT 更加便利和安全。医疗保健系统正在采用分散式照护模式,家庭治疗越来越受欢迎。报销改革和临床指南正在支持将 OPAT 纳入主流医疗。这种转变推动了对易于使用、稳定、长效且专为门诊病人设计的肠外抗生素製剂的需求。
与学名药的竞争加剧
专利到期和生物相似药开发的监管激励措施正在加速学名药的进入。学名药学名药蓬勃发展,加剧了竞争动态。为了维持市场份额,新药公司必须投资生命週期管理策略,例如配方改进和联合治疗。
新冠疫情严重扰乱了肠外抗生素市场格局,改变了需求模式和供应链运作。儘管择期手术被推迟,医院抗生素使用量减少,但重症监护室(ICU)入院人数激增,导致频谱注射剂的需求增加。生产延误和全球物流瓶颈导致关键抗生素暂时短缺。然而,这场危机加速了数位医疗的普及,包括远距处方和基于远端医疗的OPAT计画。监管机构推出了紧急途径,以确保快速核准和药品供应。疫情后的復苏目前专注于建立韧性供应链和扩展分散式医疗模式。
青霉素类药物预计将成为预测期内最大的药物
青霉素类抗生素因其广泛的疗效和成熟的临床效用,预计将在预测期内占据最大的市场份额。这些抗生素广泛用于治疗感染疾病、皮肤和尿道感染,尤其适用于住院患者。製剂稳定性和给药便捷性的不断改进巩固了其市场领先地位。频谱青霉素类抗生素与β-内酰胺酶抑制剂的联合应用增强了抗药性因应措施。青霉素类抗生素因其安全性和成本效益而受到医院的青睐,尤其是在团体治疗中。新兴趋势包括双药组合方案和纳入OPAT方案。
预计门诊手术中心部分在预测期内的复合年增长率最高
预计在预测期内,门诊手术中心细分市场将实现最高成长率,这得益于手术全期。智慧型输液系统与云端基础库存追踪的整合正在简化抗生素的管理。优惠的报销政策和更短的患者住院时间正在推动门诊手术中心的利用率。向微创手术的转变正在增加对速效注射抗生素的需求。紧凑型抗生素套件和单剂量包装的创新正根据门诊手术中心的工作流程进行客製化。
受医疗基础设施扩张和感染率上升的推动,亚太地区预计将在预测期内占据最大的市场份额。中国、印度和印尼等国家正在投资建立医院容量和抗生素生产能力。政府推动本地生产和抗生素管理的措施正在推动市场扩张。该地区的都市区地区都正在迅速普及注射疗法。全球製药公司与本地公司之间的策略合作伙伴关係正在加强分销和技术转移。新兴趋势包括人工智慧诊断和服务欠缺地区的行动门诊治疗单位 (OPAT)。
在技术创新和强劲医疗支出的推动下,北美预计将在预测期内呈现最高的复合年增长率。美国和加拿大在新型肠外抗生素製剂(例如基于脂质体和奈米颗粒的注射剂)的开发方面处于领先地位。监管机构正在简化重要抗生素的核准途径,以加快其市场准入速度。医院正在整合电子处方和智慧输液泵,以优化抗生素给药。该地区受益于强大的报销框架和对抗菌药物抗药性挑战的高度认知。随着个人化医疗和门诊治疗的扩展,北美正处于抗生素创新的前沿。
According to Stratistics MRC, the Global Parenteral Antibiotics Market is accounted for $25.74 billion in 2025 and is expected to reach $39.48 billion by 2032 growing at a CAGR of 6.3% during the forecast period. Parenteral antibiotics refer to drugs given outside the digestive system, commonly via intravenous, intramuscular, or subcutaneous injection. They are preferred for urgent treatment, cases where oral intake is not feasible, or when gastrointestinal absorption is inadequate. This method delivers the medication directly into the bloodstream, providing rapid action, greater bioavailability, and effective management of serious or widespread infections requiring immediate intervention.
According to a study published in National Canter for Biotechnology Information (NCBI) in November 2021, in Nepal, the total defined daily dose (DDD) of parenteral antibiotics reached 48,947.7 in 2019 with an increase of 23% from 39,639.7 in 2017.
Growing antimicrobial resistance (AMR)
As pathogens evolve and become resistant to conventional treatments, healthcare providers are turning to injectable formulations for faster and more effective outcomes. This trend is especially pronounced in hospital settings where multidrug-resistant infections are prevalent. Technological advancements in drug delivery systems and formulation science are enhancing the efficacy of parenteral antibiotics. The rise of precision medicine and pathogen-specific therapies is further boosting market growth. Global health agencies are also prioritizing AMR mitigation, driving investment in novel antibiotic classes and stewardship programs.
High cost of development and commercialization
Extensive clinical trials, stringent safety protocols, and compliance with global standards like FDA and EMA regulations contribute to prolonged timelines and elevated costs. Incorporating advanced technologies such as liposomal delivery and extended-release mechanisms adds complexity to the approval process. Smaller pharmaceutical firms often face resource constraints, limiting their ability to innovate or scale production. Additionally, the need for cold chain logistics and sterile packaging increases operational expenses. These factors collectively hinder rapid market entry and slow down the pace of therapeutic innovation.
Growing outpatient parenteral antibiotic therapy (OPAT)
The expansion of outpatient parenteral antibiotic therapy (OPAT) is unlocking new growth avenues for the market. OPAT enables patients to receive intravenous antibiotics outside hospital settings, reducing inpatient burden and healthcare costs. Advances in portable infusion devices and remote monitoring technologies are making OPAT more accessible and safer. Healthcare systems are increasingly adopting decentralized care models, with home-based treatments gaining traction. Reimbursement reforms and clinical guidelines are supporting OPAT integration into mainstream care. This shift is driving demand for user-friendly, stable, and long-acting parenteral antibiotic formulations tailored for outpatient use.
Increased competition from generics
Patent expirations and regulatory incentives for biosimilar development are accelerating generic entry. While generics improve accessibility, they also compress profit margins for originator companies. Technological parity in manufacturing and formulation is narrowing the differentiation gap. Emerging markets are witnessing a surge in local generic production, intensifying competitive dynamics. To maintain market share, innovators must invest in lifecycle management strategies, such as reformulations and combination therapies.
The COVID-19 pandemic significantly disrupted the parenteral antibiotics landscape, altering demand patterns and supply chain operations. Elective procedures were postponed, reducing hospital-based antibiotic usage, while ICU admissions surged, increasing demand for broad-spectrum injectables. Manufacturing delays and global logistics bottlenecks led to temporary shortages of critical antibiotics. However, the crisis accelerated digital health adoption, including remote prescribing and telemedicine-based OPAT programs. Regulatory bodies introduced emergency pathways to fast-track approvals and ensure drug availability. Post-pandemic recovery is now focused on building resilient supply chains and expanding decentralized treatment models.
The penicillinssegment is expected to be the largest during the forecast period
The penicillinssegment is expected to account for the largest market share during the forecast period, due to its broad-spectrum efficacy and established clinical utility. These antibiotics are widely used in treating respiratory, skin, and urinary tract infections, especially in inpatient settings. Continuous improvements in formulation stability and dosing convenience are reinforcing their market leadership. The development of extended-spectrum penicillins and beta-lactamase inhibitor combinations is enhancing resistance management. Hospitals favor penicillins for their safety profile and cost-effectiveness, particularly in high-volume treatment scenarios. Emerging trends include dual-drug regimens and integration into OPAT protocols.
The ambulatory surgical centerssegment is expected to have the highest CAGR during the forecast period
Over the forecast period, the ambulatory surgical centerssegment is predicted to witness the highest growth rate, driven by the rise in outpatient procedures. ASCs are increasingly performing complex surgeries that require perioperative antibiotic prophylaxis. Integration of smart infusion systems and cloud-based inventory tracking is streamlining antibiotic administration. Favorable reimbursement policies and shorter patient stays are boosting ASC utilization. The shift toward minimally invasive techniques is increasing demand for rapid-acting injectable antibiotics. Innovations in compact antibiotic kits and single-dose packaging are tailored for ASC workflows.
During the forecast period, the Asia Pacificregion is expected to hold the largest market share, supported by expanding healthcare infrastructure and rising infection rates. Countries like China, India, and Indonesia are investing in hospital capacity and antibiotic manufacturing capabilities. Government initiatives promoting local production and antimicrobial stewardship are fueling market expansion. The region is witnessing rapid adoption of injectable therapies in both urban and rural settings. Strategic collaborations between global pharmaceutical firms and regional players are enhancing distribution and technology transfer. Emerging trends include AI-assisted diagnostics and mobile OPAT units in underserved areas.
Over the forecast period, the North America region is anticipated to exhibit the highest CAGR, driven by technological innovation and robust healthcare spending. The U.S. and Canada are leading in the development of novel parenteral antibiotic formulations, including liposomal and nanoparticle-based injectables. Regulatory agencies are streamlining approval pathways for critical antibiotics, encouraging faster market entry. Hospitals are integrating electronic prescribing and smart infusion pumps to optimize antibiotic delivery. The region benefits from strong reimbursement frameworks and high awareness of AMR challenges. As personalized medicine and outpatient care expand, North America remains at the forefront of antibiotic innovation.
Key players in the market
Some of the key players in Parenteral Antibiotics Market include Pfizer Inc., Sandoz, Merck & Co., Inc., Spero Therapeutics, Johnson & Johnson, AstellasPharma Inc., GlaxoSmithKline plc, Entasis Therapeutics, Sanofi, F. Hoffmann-La Roche Ltd, Novartis AG, Bristol-Myers Squibb, Bayer AG, Eli Lilly and Company, and Abbott Laboratories.
In September2025, Pfizer Inc. and Metsera, Inc. announced the companies have entered into a definitive agreement under which Pfizer will acquire Metsera, a clinical-stage biopharmaceutical company accelerating the next generation of medicines for obesity and cardiometabolic diseases. The acquisition brings deep expertise and a portfolio of differentiated oral and injectable incretin, non-incretin and combination therapy candidates with potential best-in-class efficacy and safety profiles.
In February2025, Shedd Aquarium and global healthcare company Abbott are announcing one of Shedd's largest corporate gifts in recent history a $10 million pledge from Abbott and Abbott's philanthropic foundation, Abbott Fund. The investment cements the longstanding partnership between Shedd, Abbott, and Abbott Fund to enrich the cultural, educational and environmental fabric of Chicago and spark passion for protecting the ocean environment.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.