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市场调查报告书
商品编码
1420138
南美洲和中美洲类器官市场预测至 2030 年 - 区域分析 - 按器官类型、应用、来源和类型South & Central America Organoids Market Forecast to 2030 - Regional Analysis - by Organ Type, Application, Source, and Type |
南美洲和中美洲类器官市场预计将从2022年的1.3238亿美元成长到2030年的6.5425亿美元。预计2022年至2030年CAGR为22.1%。
专注于药物发现活动推动南美洲和中美洲类器官市场
对新药和先进药物不断增长的需求正在推动药物发现和研究的整体步伐。根据 ClinicalTrials.gov 统计,2020 年临床试验研究总数估计为 356,282 项。休布雷希特研究所最近的一项调查表明,类器官可以透过识别不太可能从该药物中受益的患者来使昂贵的药物更具成本效益。全球范围内越来越多的临床试验预计将推动对先进医疗技术(包括类器官模型)的需求。
此外,药物发现中的类器官不仅限于癌症,它们还用于其他疾病,例如囊性纤维化、多囊性肾病变、小头畸形以及肠道和气道传染病。例如,类器官可以概括器官的特性,例如器官结构和功能。此外,类器官可以恢復组织或器官的原始遗传和表观遗传状态,使它们适合基因编辑。各种研究显示了将 CRISPR-Cas9 技术与类器官结合的积极成果,这为囊性纤维化的突破提供了更多机会。根据2020 年发表的一项研究“基于CRISPR 的腺嘌呤编辑器纠正囊性纤维化类器官生物库中的无义突变”,囊性纤维化类器官生物库代表了664 名患者,其中约20%理论上能够有效修復无义突变透过腺嘌呤碱基编辑器在囊性纤维化跨膜导体受体中。儘管基因编辑类器官在一些动物模型中取得了一些成果,但其效率明显较低,成功率不高。因此,研究和开发基因编辑类器官的安全性、长期稳定性和功能性的方法至关重要。
此外,COVID-19 大流行引发了开发人类肺类器官模型的需求。例如,MilliporeSigma 开发了 3dGRO 人类肺类器官培养系统,使研究人员能够控制、存取和复製器官组织,以培养人类肺上皮类器官模型,从而有助于在研究过程中获得积极和成功的结果。因此,此类创新预计将为市场成长提供更重要的成长机会。
南美洲和中美洲类器官市场概述
南美洲和中美洲类器官市场分为巴西、阿根廷以及南美洲和中美洲其他地区。由于癌症病例数量的增加、政府措施的不断增加以及类器官研究和开发的不断增加,该地区的市场预计将增长。
南美洲及中美洲类器官市场收入及 2030 年预测(百万美元)
南美洲和中美洲类器官市场细分
南美洲和中美洲类器官市场分为器官类型、类型、应用、来源和国家。
依器官类型,南美洲和中美洲类器官市场分为肠、肝、胃、胰臟、肺、脑、肾等。 2022 年,肠道部分在南美洲和中美洲类器官市场中占据最大份额。
根据类型,南美洲和中美洲类器官市场分为仪器、消耗品和服务。 2022 年,消耗品领域在北美类器官市场中占据最大份额。
根据应用,南美洲和中美洲类器官市场分为发育生物学疾病、传染病病理学、再生医学、药物毒性和功效测试、药物发现和个人化医疗等。 2022 年,发育生物学疾病领域在南美洲和中美洲类器官市场中占据最大份额。
根据来源,南美洲和中美洲类器官市场分为多能干细胞和器官特异性成体干细胞。 2022 年,多能干细胞细分市场在南美洲和中美洲类器官市场中占有较大份额。
根据国家/地区,南美洲和中美洲类器官市场分为巴西、阿根廷以及南美洲和中美洲其他地区。 2022 年,巴西在南美洲和中美洲类器官市场占据主导地位。
Cellesce、InSphero、Merck KGaA、STEMCELL Technologies Inc 和 Thermo Fisher Scientific Inc 是南美洲和中美洲类器官市场的一些领先公司。
The South & Central America organoids market is expected to grow from US$ 132.38 million in 2022 to US$ 654.25 million by 2030. It is estimated to grow at a CAGR of 22.1% from 2022 to 2030.
Focus on Drug Discovery Activities Fuel South & Central America Organoids Market
The increasing demand for new and advanced drugs is driving the overall pace of drug discovery and research. According to ClinicalTrials.gov, the total number of clinical trial studies in 2020 was estimated to be 356,282. A recent survey by the Hubrecht Institute states that organoids can potentially make expensive drugs more cost-effective by identifying patients who are not likely to benefit from the drug. An increasing number of clinical trials worldwide is expected to drive the demand for advanced medical technologies, including organoid models.
Further, organoids in drug discovery are not limited to just cancer, they are also used in other diseases, such as cystic fibrosis, polycystic kidney disease, microcephaly, and infectious diseases of the gut and airway. For instance, organoids can summarize the properties of an organ, such as organ structure and function. Also, organoids can restore a tissue or organ's original genetic and epigenetic state, making them suitable for gene editing. Various studies have shown positive results of combining CRISPR-Cas9 technology with organoids, which has expanded opportunities for breakthroughs in cystic fibrosis. According to a study 'CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank,' published in 2020, a biobank of cystic fibrosis intestinal organoids represented 664 patients, and ~20% of them were theoretically able to efficiently repair nonsense mutations in the cystic fibrosis transmembrane conductor receptor through adenine base editors. Despite a few achievements of gene-edited organoids in some animal models, their efficiency is significantly low, and the success rate is not high. Therefore, it is crucial to research and develop a process for gene-edited organoids' safety, long-term stability, and functionality.
Moreover, the COVID-19 pandemic triggered the need to develop human lung organoid models. For instance, MilliporeSigma developed a 3dGRO Human Lung Organoid Culture System that allows researchers to control, access, and reproduce organ tissue for culturing an organoid model of human lung epithelium that can aid in obtaining positive and successful results during their research. Thus, such innovations are expected to offer more significant growth opportunities for the market growth.
South & Central America Organoids Market Overview
The South & Central America organoids market is segmented into Brazil, Argentina, and the Rest of South & Central America. The market in the region is expected to grow due to the increasing number of cancer cases, growing government initiatives, and rising research and development for organoids.
South & Central America Organoids Market Revenue and Forecast to 2030 (US$ Million)
South & Central America Organoids Market Segmentation
The South & Central America organoids market is segmented into organ type, type, application, Source, and country.
Based on organ type, the South & Central America organoids market is segmented into intestine, liver, stomach, pancreas, lung, brain, kidney, and others. The intestine segment held the largest share of the South & Central America organoids market in 2022.
Based on type, the South & Central America organoid market is segmented into instruments, consumables, and services. The consumables segment held the largest share of the North America organoid market in 2022.
Based on application, the South & Central America organoids market is segmented into developmental biology disease, pathology of infectious disease, regenerative medicine, drug toxicity and efficacy testing, drug discovery and personalized medicine, and others. The developmental biology disease segment held largest share of the South & Central America organoids market in 2022.
Based on source, the South & Central America organoids market is bifurcated into pluripotent stem cells and organ-specific adult stem cell. The pluripotent stem cells segment held the larger share of the South & Central America organoids market in 2022.
Based on country, the South & Central America organoids market is segmented into the Brazil, Argentina, and the Rest of South & Central America. Brazil dominated the South & Central America organoids market in 2022.
Cellesce, InSphero, Merck KGaA, STEMCELL Technologies Inc, and Thermo Fisher Scientific Inc, are some of the leading companies operating in the South & Central America organoids market.