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稳定同位素标记化合物市场 - 2018-2028F 全球产业规模、份额、趋势、机会和预测，按应用、物质、适应症、方法、最终用户、地区和竞争细分
市场调查报告书
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稳定同位素标记化合物市场 - 2018-2028F 全球产业规模、份额、趋势、机会和预测，按应用、物质、适应症、方法、最终用户、地区和竞争细分

Stable Isotopes Labeled Compounds Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028F Segmented By Compounds, By Application, By Substances, By Indication, By Method, By End-User, By Region and Competition
出版日期: | 出版商: TechSci Research | 英文 119 Pages | 商品交期: 2-3个工作天内

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简介目录

预计 2024 年至 2028 年预测期内，全球稳定同位素标记化合物市场将以显着速度成长。稳定同位素广泛用于环境研究，例如追踪污染物来源和研究气候变迁。对环境研究不断增长的需求预计将推动稳定同位素标记化合物市场的成长。例如，稳定同位素标记的化合物用于研究碳循环和人类活动对环境的影响。随着环境研究的需求不断增加，对稳定同位素标记化合物的需求也预计会成长。

新药和疗法的需求不断增加

市场概况
预测期 2024-2028
2022 年市场规模 30103万美元
2028 年市场规模 37626万美元
年均复合成长率（2023-2028） 3.7%
成长最快的细分市场 製药与生物技术公司
最大的市场 北美洲

由于癌症、心血管疾病和糖尿病等慢性疾病盛行率的上升，对新药和新疗法的需求不断增加。根据世界卫生组织 (WHO) 的数据，癌症是全世界死亡的一个主要因素，2020 年约有 1,000 万人因癌症死亡，约占死亡人数的六分之一。最常见的癌症是肺癌、乳癌、结肠癌、直肠癌、摄护腺癌。根据美国癌症协会 2022 年发布的报告资料，2022 年美国新增癌症病例超过 191 万例。新增病例分别为 395,600 例和 343,040 例，预计生殖系统和消化系统恶性肿瘤将占癌症病例的大多数。根据 PubMed 于 2021 年 8 月发布的资料，稳定同位素示踪是了解营养保健品影响和标靶癌症代谢的分子机制的重要方法。

稳定同位素标记的化合物使研究人员能够以无与伦比的精确度研究药物代谢和潜在毒性。透过将标记化合物放入候选药物中，科学家可以追踪其分解并识别代谢物。这些知识对于预测药物间相互作用、评估潜在的副作用以及设计提高生物利用度和降低毒性的药物至关重要。

此外，稳定同位素标记的化合物为药物在人体内的吸收、分布、代谢和排泄 (ADME) 提供了有价值的见解。透过在药物开发过程中引入标记化合物，研究人员可以追踪其命运、阐明代谢途径并评估药物清除效率。这些资讯有助于优化药物剂量、最大限度地减少潜在副作用并提高整体药物安全性。

稳定同位素标记的化合物是在其化学结构中掺入一种或多种稳定同位素（例如碳 13、氮 15 和氧 18）的合成分子。

在药物发现和开发中使用稳定同位素标记的化合物有几个优点。首先，稳定同位素是非放射性的，这使得它们在实验中处理和使用更安全。其次，稳定同位素在化学上与未标记的同位素相同，这意味着它们在生物系统中的行为是相同的。这使得研究人员能够更准确地研究药物对身体的影响。最后，稳定同位素标记提供了一种追踪药物在体内的命运的独特方法，这对于了解其药物动力学和优化其剂量至关重要。

稳定同位素标记的化合物也用于临床前研究，以研究新药的药物动力学和毒理学。这些研究对于获得新药监管部门的批准至关重要。

人们对蛋白质体学和代谢组学的兴趣日益浓厚

蛋白质体学和代谢组学是生命科学中两个快速发展的领域，它们有可能彻底改变我们对生物系统的理解，并为多种疾病开发新疗法。这些领域严重依赖稳定同位素标记化合物的使用，这些化合物是在其化学结构中掺入一种或多种稳定同位素（例如碳 13、氮 15 和氧 18）的合成分子。人们对蛋白质体学和代谢组学的兴趣日益浓厚，推动了全球稳定同位素标记化合物市场的成长，因为这些化合物在这些领域中发挥着至关重要的作用。例如，它们是稳定同位素标记技术的一部分，例如细胞培养中氨基酸稳定同位素标记 (SILAC) 和同位素编码亲和标籤 (ICAT)。稳定同位素标记在翻译后修饰 (PTM) 的研究中也发挥着至关重要的作用，这对于蛋白质功能和调节至关重要。蛋白质体学是蛋白质体的研究，蛋白质体是由细胞、组织或生物体产生的整套蛋白质。蛋白质体学研究涉及蛋白质的鑑定、定量和表征及其与其他分子的相互作用。蛋白质体学研究可以深入了解疾病的分子机制，并确定药物开发的新标靶。稳定同位素标记的化合物用于蛋白质体学研究，以研究蛋白质週转、蛋白质-蛋白质相互作用和蛋白质定位。

代谢组学是对代谢组的研究，代谢组是细胞、组织或生物体产生的整套小分子。代谢组学研究涉及代谢物的鑑定、定量和表征及其与其他分子的相互作用。稳定同位素标记的化合物用于代谢组学研究，以研究代谢通量、代谢途径和代谢调节。

稳定同位素标记的化合物对于许多蛋白质体学和代谢组学应用至关重要。例如，稳定同位素标记的氨基酸用于定量蛋白质组学实验，以比较不同样本之间的蛋白质表现量。稳定同位素标记的脂质和碳水化合物用于代谢组学实验，以研究代谢途径和代谢通量。稳定同位素标记的核苷酸用于核酸定序实验，以提高准确性并减少错误。

对个人化药物和精准药物日益增长的兴趣也推动了全球稳定同位素标记化合物市场的成长。个人化医疗和精准医疗旨在开发适合个人基因组成、生活方式和环境的治疗方法。蛋白质体学和代谢组学研究可以为开发个人化和精准医学治疗提供有价值的资讯。稳定同位素标记的化合物对于许多此类应用至关重要。

技术进步

技术进步正在推动许多产业的发展，全球稳定同位素标记化合物市场也不例外。

推动稳定同位素标记化合物市场成长的关键技术进步之一是新标记技术的开发。传统的标记技术，如同位素交换和化学合成，既耗时又昂贵，并且需要专门的设备。然而，新的标记技术，例如代谢标记、酵素标记和双正交标记，更有效率、更具成本效益，并且可以用于更广泛的应用。

代谢标记是一种涉及将稳定同位素标记的前体（例如胺基酸、核苷酸或糖）掺入活细胞或生物体中的技术。然后将这些前驱物掺入蛋白质、核酸或其他生物分子中，从而在体内产生稳定的同位素标记化合物。代谢标记是研究代谢途径、蛋白质週转和蛋白质-蛋白质相互作用的强大技术。

酶标记是一种涉及使用酶选择性地将稳定同位素标记的底物掺入特定生物分子的技术。例如，蛋白酶可用于选择性地将稳定同位素标记的胺基酸掺入特定蛋白质中，从而产生位点特异性标记的蛋白质。酵素标记是研究蛋白质功能、蛋白质-蛋白质相互作用和翻译后修饰的强大技术。

生物正交标记是一种涉及使用非天然化学反应选择性标记生物分子的技术。例如，双正交反应可用于选择性地将稳定同位素标记的糖掺入特定的醣蛋白中，从而产生位点特异性标记的醣蛋白。生物正交标记是研究复杂生物分子（例如糖蛋白）以及开发新的诊断和治疗剂的强大技术。

推动全球稳定同位素标记化合物市场成长的另一项技术进步是新分析技术的开发。质谱和核磁共振 (NMR) 光谱等分析技术对于分析稳定同位素标记的化合物及其与其他分子的相互作用至关重要。采用高解析度质谱和核磁共振波谱等新分析技术，可生产高品质、高通量和高解析度的稳定同位素标记化合物。

高解析度质谱是一种可用于精确测量稳定同位素标记化合物的质荷比的技术，从而可以对这些化合物进行识别和定量。高解析度质谱是研究蛋白质表现、代谢途径和代谢通量的强大技术。

核磁共振波谱是一种可用于确定稳定同位素标记化合物的三维结构及其与其他分子相互作用的技术。核磁共振波谱是研究蛋白质-蛋白质相互作用、蛋白质-配体相互作用和蛋白质-核酸相互作用的强大技术。

最近的发展

  • 2022 年 10 月，橡树岭国家实验室 (ORNL) 宣布将协助建造新设施，生产用于包括医药在内的多种行业的同位素。
  • 由于 Cambridge Isotope Laboratories Inc. (CIL) 和 ISOtopic Solutions 之间的合作，新型稳定同位素标记和未标记的粗脂质酵母萃取物于 2022 年 9 月上市。
  • 剑桥同位素实验室公司(CIL) 于7 月发布了首款商用的用于量子应用的富含12C 的甲烷级气体，该实验室是大冢集团的成员，也是世界领先的稳定同位素和稳定同位素标记化学品生产商2021 年。
  • 2020 年，剑桥同位素实验室 (CIL) 宣布推出一系列新的稳定同位素标记化合物用于药物开发。此系列包括常用药物的氘标记类似物，例如布洛芬和萘普生，旨在提高药物疗效并降低毒性。这些化合物在开发一系列疾病的新疗法方面具有潜在的应用。
  • 2020 年，格拉斯哥大学的一组研究人员开发了一种新的稳定同位素标记化合物，用于分析柠檬酸循环（关键的代谢途径）。
  • 2020年，加兴同位素技术公司（ITG）宣布与德国癌症研究中心（DKFZ）建立合作关係，开发用于癌症诊断和治疗的新型放射性药物。

市场区隔

全球稳定同位素标记化合物市场按化合物、应用、物质、适应症、方法、最终用户、地区和公司细分。依化合物，市场可分为碳（13C）、氮（15N）、氘、氧（18O）等。根据应用，市场可分为诊断、药物发现、影像、灭菌等。根据物质，市场可分为核酸、胺基酸、药物/代谢物、脂肪酸/脂质、核磁共振溶剂等。根据适应症，市场可以进一步细分为心臟病学、神经学、发炎、代谢疾病等。根据方法，市场可分为化学和细胞培养。根据最终用户，市场可分为製药和生技公司、学术机构等。

市场参与者

全球稳定同位素标记化合物市场的主要参与者包括 PerkinElmer Inc.、Merck KGaA、3M Company、Cambridge Isotope Laboratories, Inc.、JSC Isotope、Creative Proteomics、Medical Isotopes, Inc.、Omicron Biochemicals, Inc.、Trace Sciences International、和日本酸素控股公司。

报告范围：

在本报告中，除了以下详细介绍的产业趋势外，全球稳定同位素标记化合物市场也分为以下几类：

稳定同位素标记化合物市场（依化合物）：

  • 碳 (13C)
  • 氮气(15N)
  • 氘
  • 氧气(18O)
  • 其他的

稳定同位素标记化合物市场，按应用：

  • 诊断
  • 药物发现
  • 影像学
  • 消毒
  • 其他的

稳定同位素标记化合物市场，依物质划分：

  • 核酸
  • 胺基酸
  • 药物/代谢物
  • 脂肪酸/脂质
  • 核磁共振溶剂
  • 其他的

稳定同位素标记化合物市场，依适应症分类：

  • 心臟病学
  • 神经病学
  • 发炎
  • 代谢性疾病
  • 其他的

稳定同位素标记化合物市场，依方法划分：

  • 化学
  • 细胞培养

稳定同位素标记化合物市场，依最终用户划分：

  • 製药和生物技术公司
  • 学术机构
  • 其他的

稳定同位素标记化合物市场，按地区：

  • 亚太
    • 中国
    • 印度
    • 日本
    • 韩国
    • 澳洲
  • 欧洲
    • 法国
    • 德国
    • 英国
    • 义大利
    • 西班牙
  • 北美洲
    • 美国
    • 墨西哥
    • 加拿大
  • 南美洲
    • 巴西
    • 阿根廷
    • 哥伦比亚
  • 中东和非洲
    • 南非
    • 沙乌地阿拉伯
    • 阿联酋

竞争格局

公司简介：对全球稳定同位素标记化合物市场中主要公司的详细分析。

可用的客製化：

根据给定的市场资料，TechSci Research 可根据公司的具体需求提供客製化服务。该报告可以使用以下自订选项：

公司资讯

  • 其他市场参与者（最多五个）的详细分析和概况分析。

目录

第 1 章：产品概述

  • 市场定义
  • 市场范围
    • 涵盖的市场
    • 考虑学习的年份
    • 主要市场区隔

第 2 章：研究方法

  • 研究目的
  • 基线方法
  • 主要产业伙伴
  • 主要协会和二手资料来源
  • 预测方法
  • 数据三角测量与验证
  • 假设和限制

第 3 章：执行摘要

  • 市场概况
  • 主要市场细分概述
  • 主要市场参与者概述
  • 重点地区/国家概况
  • 市场驱动因素、挑战、趋势概述

第 4 章：客户之声

第 5 章：全球稳定同位素标记化合物市场展望

  • 市场规模及预测
    • 按价值
  • 市占率及预测
    • 依化合物分类（碳 (13C)、氮 (15N)、氘、氧 (18O)、其他）
    • 按应用（诊断、药物发现、影像、灭菌、其他）
    • 依物质（核酸、胺基酸、药物/代谢物、脂肪酸/脂质、NMR 溶剂等）
    • 按适应症（心臟科、神经学、发炎、代谢疾病等）
    • 依方法（化学、细胞培养）
    • 按最终用户（製药和生物技术公司、学术机构等）
    • 按地区
    • 按公司划分 (2022)
  • 市场地图
    • 按化合物分类
    • 按应用
    • 按物质分类
    • 按指示
    • 依方法
    • 按最终用户

第 6 章：亚太地区稳定同位素标记化合物市场展望

  • 市场规模及预测
    • 按价值
  • 市占率及预测
    • 依化合物分类（碳 (13C)、氮 (15N)、氘、氧 (18O)、其他）
    • 按应用（诊断、药物发现、影像、灭菌、其他）
    • 依物质（核酸、胺基酸、药物/代谢物、脂肪酸/脂质、NMR 溶剂等）
    • 按适应症（心臟科、神经学、发炎、代谢疾病等）
    • 依方法（化学、细胞培养）
    • 按最终用户（製药和生物技术公司、学术机构等）
    • 按国家/地区
  • 亚太地区：国家分析
    • 中国
    • 印度
    • 日本
    • 韩国
    • 澳洲

第 7 章：欧洲稳定同位素标记化合物市场展望

  • 市场规模及预测
    • 按价值
  • 市占率及预测
    • 依化合物分类（碳 (13C)、氮 (15N)、氘、氧 (18O)、其他）
    • 按应用（诊断、药物发现、影像、灭菌、其他）
    • 依物质（核酸、胺基酸、药物/代谢物、脂肪酸/脂质、NMR 溶剂等）
    • 按适应症（心臟科、神经学、发炎、代谢疾病等）
    • 依方法（化学、细胞培养）
    • 按最终用户（製药和生物技术公司、学术机构等）
    • 按国家/地区
  • 欧洲：国家分析
    • 法国
    • 德国
    • 英国
    • 义大利
    • 西班牙

第 8 章：北美稳定同位素标记化合物市场展望

  • 市场规模及预测
    • 按价值
  • 市占率及预测
    • 依化合物分类（碳 (13C)、氮 (15N)、氘、氧 (18O)、其他）
    • 按应用（诊断、药物发现、影像、灭菌、其他）
    • 依物质（核酸、胺基酸、药物/代谢物、脂肪酸/脂质、NMR 溶剂等）
    • 按适应症（心臟科、神经学、发炎、代谢疾病等）
    • 依方法（化学、细胞培养）
    • 按最终用户（製药和生物技术公司、学术机构等）
    • 按国家/地区
  • 北美：国家分析
    • 美国
    • 墨西哥
    • 加拿大

第 9 章：南美洲稳定同位素标记化合物市场展望

  • 市场规模及预测
    • 按价值
  • 市占率及预测
    • 依化合物分类（碳 (13C)、氮 (15N)、氘、氧 (18O)、其他）
    • 按应用（诊断、药物发现、影像、灭菌、其他）
    • 依物质（核酸、胺基酸、药物/代谢物、脂肪酸/脂质、NMR 溶剂等）
    • 按适应症（心臟科、神经学、发炎、代谢疾病等）
    • 依方法（化学、细胞培养）
    • 按最终用户（製药和生物技术公司、学术机构等）
    • 按国家/地区
  • 南美洲：国家分析
    • 巴西
    • 阿根廷
    • 哥伦比亚

第 10 章：中东和非洲稳定同位素标记化合物市场展望

  • 市场规模及预测
    • 按价值
  • 市占率及预测
    • 依化合物分类（碳 (13C)、氮 (15N)、氘、氧 (18O)、其他）
    • 按应用（诊断、药物发现、影像、灭菌、其他）
    • 依物质（核酸、胺基酸、药物/代谢物、脂肪酸/脂质、NMR 溶剂等）
    • 按适应症（心臟科、神经学、发炎、代谢疾病等）
    • 依方法（化学、细胞培养）
    • 按最终用户（製药和生物技术公司、学术机构等）
    • 按国家/地区
  • MEA：国家分析
    • 南非稳定同位素标记化合物
    • 沙乌地阿拉伯稳定同位素标记化合物
    • 阿联酋稳定同位素标记化合物

第 11 章：市场动态

  • 司机
  • 挑战

第 12 章：市场趋势与发展

  • 併购
  • 产品发布
  • 技术进步

第13章：竞争格局

  • 商业概览
  • 公司概况
  • 产品与服务
  • 财务（据报导）
  • 最近的发展
  • SWOT分析
    • PerkinElmer Inc.
    • Merck KGaA
    • 3M Company
    • Cambridge Isotope Laboratories, Inc.
    • JSC Isotope
    • Creative Proteomics
    • Medical Isotopes, Inc.
    • Omicron Biochemicals, Inc.
    • Trace Sciences International
    • Nippon Sanso Holdings Corporation

第 14 章：策略建议

简介目录
Product Code: 4565

Global stable isotopes labeled compounds market is expected to grow at a significant rate during the forecast period 2024-2028. Stable isotopes are extensively used in environmental studies, such as tracing the sources of pollutants and studying climate change. The growing demand for environmental studies is expected to drive the growth of the stable isotopes labeled compounds market. For example, stable isotope labeled compounds are used to study the carbon cycle and the impact of human activities on the environment. As the demand for environmental studies continues to increase, the demand for stable isotopes labeled compounds is expected to grow.

Stable isotopes are non-radioactive isotopes that have the same number of protons but different numbers of neutrons in their atomic nuclei. They are used extensively in a wide range of scientific and industrial applications, including research, medicine, agriculture, and environmental studies. Stable isotopes labeled compounds are synthetic molecules that incorporate one or more stable isotopes, often carbon-13, nitrogen-15, and oxygen-18, into their chemical structure. These labeled compounds are used to investigate metabolic pathways, study protein-protein interactions, and develop new drugs, which will propel the global stable isotopes labeled compounds market.

Increasing Demand for New Drugs and Therapies

Market Overview
Forecast Period2024-2028
Market Size 2022USD 301.03 Million
Market Size 2028USD 376.26 Million
CAGR (2023-2028)3.7%
Fastest Growing SegmentPharmaceutical & Biotechnology Companies
Largest MarketNorth America

The demand for new drugs and therapies is constantly increasing, driven by the rising prevalence of chronic diseases such as cancer, cardiovascular diseases, and diabetes. According to the World Health Organization (WHO), cancer is a major factor for the cause of death across the world, accounting for approximately 10 million deaths in 2020, or about one in six deaths. The most common cancers are lung, breast, colon and rectum, and prostate cancers. There were over 1.91 million new cancer cases in the United States in 2022, according to data from the American Cancer Society report, publsihed in 2022. With 395,600 and 343,040 new cases, respectively, it is anticipated that malignancies of the genital and digestive systems will account for the majority of cancer cases. Stable isotope tracing is a crucial method for understanding the molecular mechanisms by which nutraceuticals affect and target cancer metabolism, according to data that was published by PubMed in August 2021.

Stable isotopes labeled compounds enable researchers to study drug metabolism and potential toxicity with unparalleled precision. By putting a labeled compound into a drug candidate, scientists can track its breakdown and identify metabolites. This knowledge is crucial in predicting drug-drug interactions, evaluating potential adverse effects, and designing drugs with improved bioavailability and reduced toxicity.

Moreover, stable isotopes labeled compounds offer valuable insights into the absorption, distribution, metabolism, and excretion (ADME) of drugs in the human body. By introducing a labeled compound during drug development, researchers can track its fate, elucidate metabolic pathways, and assess the efficiency of drug clearance. This information aids in optimizing drug dosage, minimizing potential side effects, and improving overall drug safety.

Stable isotope labeled compounds are synthetic molecules that incorporate one or more stable isotopes, such as carbon-13, nitrogen-15, and oxygen-18, into their chemical structure.

The use of stable isotope labeled compounds in drug discovery and development has several advantages. Firstly, stable isotopes are non-radioactive, which makes them safer to handle and use in experiments. Secondly, stable isotopes are chemically identical to their non-labeled counterparts, which means that their behavior in biological systems is the same. This allows researchers to study the effects of drugs on the body more accurately. Finally, stable isotope labeling provides a unique way to track the fate of a drug in the body, which is essential for understanding its pharmacokinetics and optimizing its dosage.

Stable isotope labeled compounds are also used in preclinical studies to investigate the pharmacokinetics and toxicology of new drugs. These studies are essential for obtaining regulatory approval for new drugs.

Growing Interest in Proteomics and Metabolomics

Proteomics and metabolomics are two rapidly growing fields in life sciences that have the potential to revolutionize our understanding of biological systems and develop new therapies for a wide range of diseases. These fields rely heavily on the use of stable isotope labeled compounds, which are synthetic molecules that incorporate one or more stable isotopes, such as carbon-13, nitrogen-15, and oxygen-18, into their chemical structure. The growing interest in proteomics and metabolomics is driving the growth of the global stable isotopes labeled compounds market, as these compounds play a crucial role in these fields. For example, they are a part of stable isotope labeling techniques, such as Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC) and Isotope-Coded Affinity Tag (ICAT). Stable isotope labeling also plays a crucial role in studying Post-Translational Modifications (PTMs), which are essential for protein functionality and regulation. Proteomics is the study of the proteome, which is the entire set of proteins produced by a cell, tissue, or organism. Proteomics research involves the identification, quantification, and characterization of proteins and their interactions with other molecules. Proteomics research can provide insights into the molecular mechanisms underlying diseases and identify new targets for drug development. Stable isotopes labeled compounds are used in proteomics research to study protein turnover, protein-protein interactions, and protein localization.

Metabolomics is the study of the metabolome, which is the entire set of small molecules produced by a cell, tissue, or organism. Metabolomics research involves the identification, quantification, and characterization of metabolites and their interactions with other molecules. Stable isotopes labeled compounds are used in metabolomics research to study metabolic flux, metabolic pathways, and metabolic regulation.

Stable isotopes labeled compounds are essential for many proteomics and metabolomics applications. For example, stable isotope labeled amino acids are used in quantitative proteomics experiments to compare protein expression levels between different samples. Stable isotope labeled lipids and carbohydrates are used in metabolomics experiments to study metabolic pathways and metabolic flux. Stable isotope labeled nucleotides are used in nucleic acid sequencing experiments to improve accuracy and reduce errors.

The growing interest in personalized medicines and precision medicines is also driving the growth of the global stable isotopes labeled compounds market. Personalized medicine and precision medicine aim to develop treatments that are tailored to an individual's genetic makeup, lifestyle, and environment. Proteomics and metabolomics research can provide valuable information for developing personalized and precision medicine treatments. Stable isotope labeled compounds are essential for many of these applications.

Technological Advancements

Technological advancements are driving the growth of many industries, and the global stable isotopes labeled compounds market is no exception.

One of the key technological advancements driving the growth of the stable isotopes labeled compounds market is the development of new labeling techniques. Traditional labeling techniques, such as isotopic exchange and chemical synthesis, are time-consuming, expensive, and require specialized equipment. However, new labeling techniques, such as metabolic labeling, enzymatic labeling, and biorthogonal labeling, are more efficient, cost-effective, and can be used in a wider range of applications.

Metabolic labeling is a technique that involves incorporating stable isotope labeled precursors, such as amino acids, nucleotides, or sugars, into living cells or organisms. These precursors are then incorporated into proteins, nucleic acids, or other biomolecules, allowing for the production of stable isotope labeled compounds in vivo. Metabolic labeling is a powerful technique for studying metabolic pathways, protein turnover, and protein-protein interactions.

Enzymatic labeling is a technique that involves using enzymes to selectively incorporate stable isotope labeled substrates into specific biomolecules. For example, a protease enzyme can be used to selectively incorporate stable isotope labeled amino acids into specific proteins, allowing for the production of site-specifically labeled proteins. Enzymatic labeling is a powerful technique for studying protein function, protein-protein interactions, and post-translational modifications.

Biorthogonal labeling is a technique that involves using non-natural chemical reactions to selectively label biomolecules. For example, a biorthogonal reaction can be used to selectively incorporate stable isotope labeled sugars into specific glycoproteins, allowing for the production of site-specifically labeled glycoproteins. Biorthogonal labeling is a powerful technique for studying complex biomolecules, such as glycoproteins, and for developing new diagnostic and therapeutic agents.

Another technological advancement driving the growth of the global stable isotopes labeled compounds market is the development of new analytical techniques. Analytical techniques, such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy, are essential for analyzing stable isotope labeled compounds and their interactions with other molecules. The adoption of new analytical techniques, such as high-resolution mass spectrometry and NMR spectroscopy, is enabling the production of high-quality, high-throughput, and high-resolution stable isotope labeled compounds.

High-resolution mass spectrometry is a technique that can be used to accurately measure the mass-to-charge ratio of stable isotope labeled compounds, allowing for the identification and quantification of these compounds. High-resolution mass spectrometry is a powerful technique for studying protein expression, metabolic pathways, and metabolic flux.

Nuclear magnetic resonance spectroscopy is a technique that can be used to determine the three-dimensional structure of stable isotope labeled compounds and their interactions with other molecules. NMR spectroscopy is a powerful technique for studying protein-protein interactions, protein-ligand interactions, and protein-nucleic acid interactions.

Recent Developments

  • In October 2022, Oak Ridge National Laboratory (ORNL) announced that it would contribute to the construction of new facilities to produce isotopes used in a variety of industries, including medicine.
  • The novel stable isotope-labeled and unlabeled Crude Lipid Yeast Extract was made available in September 2022, thanks to a collaboration between Cambridge Isotope Laboratories Inc. (CIL) and ISOtopic Solutions.
  • The first commercially accessible 12C-enriched methane-grade gas for quantum applications was released by Cambridge Isotope Laboratories, Inc. (CIL), a member of the Otsuka Group and the world's leading producer of stable isotopes and stable isotope-labeled chemicals, in July 2021.
  • In 2020, Cambridge Isotope Laboratories (CIL) announced the launch of a new range of stable isotope labeled compounds for drug development. This range includes deuterium-labeled analogs of commonly used drugs, such as ibuprofen and naproxen, which are designed to improve drug efficacy and reduce toxicity. These compounds have potential applications in the development of new therapeutics for a range of diseases.
  • In 2020, a team of researchers from the University of Glasgow developed a new stable isotope labeled compound for the analysis of the citric acid cycle, a key metabolic pathway.
  • In 2020, Isotope Technologies Garching (ITG) announced a partnership with the German Cancer Research Center (DKFZ) to develop new radiopharmaceuticals for cancer diagnosis and treatment.

Market Segmentation

The global stable isotopes labeled compounds market is segmented by compounds, application, substances, indication, method, end-user, region and company. Based on compounds, the market can be segmented into carbon (13C), nitrogen(15N), deuterium, oxygen(18O), and others. On the basis of application, the market can be categorized as diagnosis, drug discovery, imaging, sterilization, and others. Based on substances, the market can be fragmented into nucleic acids, amino acids, drugs/metabolites, fatty acids /lipids, NMR solvents and others. On the basis of indication, the market can be further segmented into cardiology, neurology, inflammation, metabolic disease, and others. Based on method, the market can be split into chemical and cell-culturing. On the basis of end-user, the market can be categorized into pharmaceutical and biotechnology companies, academic institutes, and others.

Market Players

Major players of the global stable isotopes labeled compounds market include PerkinElmer Inc., Merck KGaA, 3M Company, Cambridge Isotope Laboratories, Inc., JSC Isotope, Creative Proteomics, Medical Isotopes, Inc., Omicron Biochemicals, Inc., Trace Sciences International, and Nippon Sanso Holdings Corporation.

Report Scope:

In this report, global stable isotopes labeled compounds market has been segmented into following categories, in addition to the industry trends which have also been detailed below:

Stable Isotopes Labeled Compounds Market, By Compounds:

  • Carbon (13C)
  • Nitrogen(15N)
  • Deuterium
  • Oxygen(18O)
  • Others

Stable Isotopes Labeled Compounds Market, By Application:

  • Diagnosis
  • Drug Discovery
  • Imaging
  • Sterilization
  • Others

Stable Isotopes Labeled Compounds Market, By Substances:

  • Nucleic Acids
  • Amino Acids
  • Drugs/Metabolites
  • Fatty Acids/Lipids
  • NMR Solvents
  • Others

Stable Isotopes Labeled Compounds Market, By Indication:

  • Cardiology
  • Neurology
  • Inflammation
  • Metabolic Disease
  • Others

Stable Isotopes Labeled Compounds Market, By Method:

  • Chemical
  • Cell-culturing

Stable Isotopes Labeled Compounds Market, By End-User:

  • Pharmaceutical and Biotechnology Companies
  • Academic Institute
  • Others

Stable Isotopes Labeled Compounds Market, By Region:

  • Asia-Pacific
    • China
    • India
    • Japan
    • South Korea
    • Australia
  • Europe
    • France
    • Germany
    • United Kingdom
    • Italy
    • Spain
  • North America
    • United States
    • Mexico
    • Canada
  • South America
    • Brazil
    • Argentina
    • Colombia
  • Middle East & Africa
    • South Africa
    • Saudi Arabia
    • UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the global stable isotopes labeled compounds market.

Available Customizations:

With the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

  • Detailed analysis and profiling of additional market players (up to five).

Table of Contents

1. Product Overview

  • 1.1. Market Definition
  • 1.2. Scope of the Market
    • 1.2.1. Markets Covered
    • 1.2.2. Years Considered for Study
    • 1.2.3. Key Market Segmentations

2. Research Methodology

  • 2.1. Objective of the Study
  • 2.2. Baseline Methodology
  • 2.3. Key Industry Partners
  • 2.4. Major Association and Secondary Sources
  • 2.5. Forecasting Methodology
  • 2.6. Data Triangulation & Validation
  • 2.7. Assumptions and Limitations

3. Executive Summary

  • 3.1. Overview of the Market
  • 3.2. Overview of Key Market Segmentations
  • 3.3. Overview of Key Market Players
  • 3.4. Overview of Key Regions/Countries
  • 3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global Stable Isotopes Labeled Compounds Market Outlook

  • 5.1. Market Size & Forecast
    • 5.1.1. By Value
  • 5.2. Market Share & Forecast
    • 5.2.1. By Compounds (Carbon (13C), Nitrogen(15N), Deuterium, Oxygen(18O), Others)
    • 5.2.2. By Application (Diagnosis, Drug Discovery, Imaging, Sterilization, Others)
    • 5.2.3. By Substances (Nucleic Acids, Amino Acids, Drugs/Metabolites, Fatty Acids /Lipids, NMR Solvents and Others)
    • 5.2.4. By Indication (Cardiology, Neurology, Inflammation, Metabolic disease and Others)
    • 5.2.5. By Method (Chemical, Cell-culturing)
    • 5.2.6. By End-User (Pharmaceutical and Biotechnology Companies, Academic Institute and Others)
    • 5.2.7. By Region
    • 5.2.8. By Company (2022)
  • 5.3. Market Map
    • 5.3.1. By Compounds
    • 5.3.2. By Application
    • 5.3.3. By Substances
    • 5.3.4. By Indication
    • 5.3.5. By Method
    • 5.3.6. By End-User

6. Asia-Pacific Stable Isotopes Labeled Compounds Market Outlook

  • 6.1. Market Size & Forecast
    • 6.1.1. By Value
  • 6.2. Market Share & Forecast
    • 6.2.1. By Compounds (Carbon (13C), Nitrogen(15N), Deuterium, Oxygen(18O), Others)
    • 6.2.2. By Application (Diagnosis, Drug Discovery, Imaging, Sterilization, Others)
    • 6.2.3. By Substances (Nucleic Acids, Amino Acids, Drugs/Metabolites, Fatty Acids /Lipids, NMR Solvents and Others)
    • 6.2.4. By Indication (Cardiology, Neurology, Inflammation, Metabolic disease and Others)
    • 6.2.5. By Method (Chemical, Cell-culturing)
    • 6.2.6. By End-User (Pharmaceutical and Biotechnology Companies, Academic Institute and Others)
    • 6.2.7. By Country
  • 6.3. Asia-Pacific: Country Analysis
    • 6.3.1. China Stable Isotopes Labeled Compounds Market Outlook
      • 6.3.1.1. Market Size & Forecast
        • 6.3.1.1.1. By Value
      • 6.3.1.2. Market Share & Forecast
        • 6.3.1.2.1. By Compounds
        • 6.3.1.2.2. By Application
        • 6.3.1.2.3. By Substances
        • 6.3.1.2.4. By Indication
        • 6.3.1.2.5. By Method
        • 6.3.1.2.6. By End-User
    • 6.3.2. India Stable Isotopes Labeled Compounds Market Outlook
      • 6.3.2.1. Market Size & Forecast
        • 6.3.2.1.1. By Value
      • 6.3.2.2. Market Share & Forecast
        • 6.3.2.2.1. By Compounds
        • 6.3.2.2.2. By Application
        • 6.3.2.2.3. By Substances
        • 6.3.2.2.4. By Indication
        • 6.3.2.2.5. By Method
        • 6.3.2.2.6. By End-User
    • 6.3.3. Japan Stable Isotopes Labeled Compounds Market Outlook
      • 6.3.3.1. Market Size & Forecast
        • 6.3.3.1.1. By Value
      • 6.3.3.2. Market Share & Forecast
        • 6.3.3.2.1. By Compounds
        • 6.3.3.2.2. By Application
        • 6.3.3.2.3. By Substances
        • 6.3.3.2.4. By Indication
        • 6.3.3.2.5. By Method
        • 6.3.3.2.6. By End-User
    • 6.3.4. South Korea Stable Isotopes Labeled Compounds Market Outlook
      • 6.3.4.1. Market Size & Forecast
        • 6.3.4.1.1. By Value
      • 6.3.4.2. Market Share & Forecast
        • 6.3.4.2.1. By Compounds
        • 6.3.4.2.2. By Application
        • 6.3.4.2.3. By Substances
        • 6.3.4.2.4. By Indication
        • 6.3.4.2.5. By Method
        • 6.3.4.2.6. By End-User
    • 6.3.5. Australia Stable Isotopes Labeled Compounds Market Outlook
      • 6.3.5.1. Market Size & Forecast
        • 6.3.5.1.1. By Value
      • 6.3.5.2. Market Share & Forecast
        • 6.3.5.2.1. By Compounds
        • 6.3.5.2.2. By Application
        • 6.3.5.2.3. By Substances
        • 6.3.5.2.4. By Indication
        • 6.3.5.2.5. By Method
        • 6.3.5.2.6. By End-User

7. Europe Stable Isotopes Labeled Compounds Market Outlook

  • 7.1. Market Size & Forecast
    • 7.1.1. By Value
  • 7.2. Market Share & Forecast
    • 7.2.1. By Compounds (Carbon (13C), Nitrogen(15N), Deuterium, Oxygen(18O), Others)
    • 7.2.2. By Application (Diagnosis, Drug Discovery, Imaging, Sterilization, Others)
    • 7.2.3. By Substances (Nucleic Acids, Amino Acids, Drugs/Metabolites, Fatty Acids /Lipids, NMR Solvents and Others)
    • 7.2.4. By Indication (Cardiology, Neurology, Inflammation, Metabolic Disease and Others)
    • 7.2.5. By Method (Chemical, Cell-culturing)
    • 7.2.6. By End-User (Pharmaceutical and Biotechnology Companies, Academic Institute and Others)
    • 7.2.7. By Country
  • 7.3. Europe: Country Analysis
    • 7.3.1. France Stable Isotopes Labeled Compounds Market Outlook
      • 7.3.1.1. Market Size & Forecast
        • 7.3.1.1.1. By Value
      • 7.3.1.2. Market Share & Forecast
        • 7.3.1.2.1. By Compounds
        • 7.3.1.2.2. By Application
        • 7.3.1.2.3. By Substances
        • 7.3.1.2.4. By Indication
        • 7.3.1.2.5. By Method
        • 7.3.1.2.6. By End-User
    • 7.3.2. Germany Stable Isotopes Labeled Compounds Market Outlook
      • 7.3.2.1. Market Size & Forecast
        • 7.3.2.1.1. By Value
      • 7.3.2.2. Market Share & Forecast
        • 7.3.2.2.1. By Compounds
        • 7.3.2.2.2. By Application
        • 7.3.2.2.3. By Substances
        • 7.3.2.2.4. By Indication
        • 7.3.2.2.5. By Method
        • 7.3.2.2.6. By End-User
    • 7.3.3. United Kingdom Stable Isotopes Labeled Compounds Market Outlook
      • 7.3.3.1. Market Size & Forecast
        • 7.3.3.1.1. By Value
      • 7.3.3.2. Market Share & Forecast
        • 7.3.3.2.1. By Compounds
        • 7.3.3.2.2. By Application
        • 7.3.3.2.3. By Substances
        • 7.3.3.2.4. By Indication
        • 7.3.3.2.5. By Method
        • 7.3.3.2.6. By End-User
    • 7.3.4. Italy Stable Isotopes Labeled Compounds Market Outlook
      • 7.3.4.1. Market Size & Forecast
        • 7.3.4.1.1. By Value
      • 7.3.4.2. Market Share & Forecast
        • 7.3.4.2.1. By Compounds
        • 7.3.4.2.2. By Application
        • 7.3.4.2.3. By Substances
        • 7.3.4.2.4. By Indication
        • 7.3.4.2.5. By Method
        • 7.3.4.2.6. By End-User
    • 7.3.5. Spain Stable Isotopes Labeled Compounds Market Outlook
      • 7.3.5.1. Market Size & Forecast
        • 7.3.5.1.1. By Value
      • 7.3.5.2. Market Share & Forecast
        • 7.3.5.2.1. By Compounds
        • 7.3.5.2.2. By Application
        • 7.3.5.2.3. By Substances
        • 7.3.5.2.4. By Indication
        • 7.3.5.2.5. By Method
        • 7.3.5.2.6. By End-User

8. North America Stable Isotopes Labeled Compounds Market Outlook

  • 8.1. Market Size & Forecast
    • 8.1.1. By Value
  • 8.2. Market Share & Forecast
    • 8.2.1. By Compounds (Carbon (13C), Nitrogen(15N), Deuterium, Oxygen(18O), Others)
    • 8.2.2. By Application (Diagnosis, Drug Discovery, Imaging, Sterilization, Others)
    • 8.2.3. By Substances (Nucleic Acids, Amino Acids, Drugs/Metabolites, Fatty Acids /Lipids, NMR Solvents and Others)
    • 8.2.4. By Indication (Cardiology, Neurology, Inflammation, Metabolic disease and Others)
    • 8.2.5. By Method (Chemical, Cell-culturing)
    • 8.2.6. By End-User (Pharmaceutical and Biotechnology Companies, Academic Institute and Others)
    • 8.2.7. By Country
  • 8.3. North America: Country Analysis
    • 8.3.1. United States Stable Isotopes Labeled Compounds Market Outlook
      • 8.3.1.1. Market Size & Forecast
        • 8.3.1.1.1. By Value
      • 8.3.1.2. Market Share & Forecast
        • 8.3.1.2.1. By Compounds
        • 8.3.1.2.2. By Application
        • 8.3.1.2.3. By Substances
        • 8.3.1.2.4. By Indication
        • 8.3.1.2.5. By Method
        • 8.3.1.2.6. By End-User
    • 8.3.2. Mexico Stable Isotopes Labeled Compounds Market Outlook
      • 8.3.2.1. Market Size & Forecast
        • 8.3.2.1.1. By Value
      • 8.3.2.2. Market Share & Forecast
        • 8.3.2.2.1. By Compounds
        • 8.3.2.2.2. By Application
        • 8.3.2.2.3. By Substances
        • 8.3.2.2.4. By Indication
        • 8.3.2.2.5. By Method
        • 8.3.2.2.6. By End-User
    • 8.3.3. Canada Stable Isotopes Labeled Compounds Market Outlook
      • 8.3.3.1. Market Size & Forecast
        • 8.3.3.1.1. By Value
      • 8.3.3.2. Market Share & Forecast
        • 8.3.3.2.1. By Compounds
        • 8.3.3.2.2. By Application
        • 8.3.3.2.3. By Substances
        • 8.3.3.2.4. By Indication
        • 8.3.3.2.5. By Method
        • 8.3.3.2.6. By End-User

9. South America Stable Isotopes Labeled Compounds Market Outlook

  • 9.1. Market Size & Forecast
    • 9.1.1. By Value
  • 9.2. Market Share & Forecast
    • 9.2.1. By Compounds (Carbon (13C), Nitrogen(15N), Deuterium, Oxygen(18O), Others)
    • 9.2.2. By Application (Diagnosis, Drug Discovery, Imaging, Sterilization, Others)
    • 9.2.3. By Substances (Nucleic Acids, Amino Acids, Drugs/Metabolites, Fatty Acids /Lipids, NMR Solvents and Others)
    • 9.2.4. By Indication (Cardiology, Neurology, Inflammation, Metabolic disease and Others)
    • 9.2.5. By Method (Chemical, Cell-culturing)
    • 9.2.6. By End-User (Pharmaceutical and Biotechnology Companies, Academic Institute and Others)
    • 9.2.7. By Country
  • 9.3. South America: Country Analysis
    • 9.3.1. Brazil Stable Isotopes Labeled Compounds Market Outlook
      • 9.3.1.1. Market Size & Forecast
        • 9.3.1.1.1. By Value
      • 9.3.1.2. Market Share & Forecast
        • 9.3.1.2.1. By Compounds
        • 9.3.1.2.2. By Application
        • 9.3.1.2.3. By Substances
        • 9.3.1.2.4. By Indication
        • 9.3.1.2.5. By Method
        • 9.3.1.2.6. By End-User
    • 9.3.2. Argentina Stable Isotopes Labeled Compounds Market Outlook
      • 9.3.2.1. Market Size & Forecast
        • 9.3.2.1.1. By Value
      • 9.3.2.2. Market Share & Forecast
        • 9.3.2.2.1. By Compounds
        • 9.3.2.2.2. By Application
        • 9.3.2.2.3. By Substances
        • 9.3.2.2.4. By Indication
        • 9.3.2.2.5. By Method
        • 9.3.2.2.6. By End-User
    • 9.3.3. Colombia Stable Isotopes Labeled Compounds Market Outlook
      • 9.3.3.1. Market Size & Forecast
        • 9.3.3.1.1. By Value
      • 9.3.3.2. Market Share & Forecast
        • 9.3.3.2.1. By Compounds
        • 9.3.3.2.2. By Application
        • 9.3.3.2.3. By Substances
        • 9.3.3.2.4. By Indication
        • 9.3.3.2.5. By Method
        • 9.3.3.2.6. By End-User

10. Middle East and Africa Stable Isotopes Labeled Compounds Market Outlook

  • 10.1. Market Size & Forecast
    • 10.1.1. By Value
  • 10.2. Market Share & Forecast
    • 10.2.1. By Compounds (Carbon (13C), Nitrogen(15N), Deuterium, Oxygen(18O), Others)
    • 10.2.2. By Application (Diagnosis, Drug Discovery, Imaging, Sterilization, Others)
    • 10.2.3. By Substances (Nucleic Acids, Amino Acids, Drugs/Metabolites, Fatty Acids /Lipids, NMR Solvents and Others)
    • 10.2.4. By Indication (Cardiology, Neurology, Inflammation, Metabolic disease and Others)
    • 10.2.5. By Method (Chemical, Cell-culturing)
    • 10.2.6. By End-User (Pharmaceutical and Biotechnology Companies, Academic Institute and Others)
    • 10.2.7. By Country
  • 10.3. MEA: Country Analysis
    • 10.3.1. South Africa Stable Isotopes Labeled Compounds Market Outlook
      • 10.3.1.1. Market Size & Forecast
        • 10.3.1.1.1. By Value
      • 10.3.1.2. Market Share & Forecast
        • 10.3.1.2.1. By Compounds
        • 10.3.1.2.2. By Application
        • 10.3.1.2.3. By Substances
        • 10.3.1.2.4. By Indication
        • 10.3.1.2.5. By Method
        • 10.3.1.2.6. By End-User
    • 10.3.2. Saudi Arabia Stable Isotopes Labeled Compounds Market Outlook
      • 10.3.2.1. Market Size & Forecast
        • 10.3.2.1.1. By Value
      • 10.3.2.2. Market Share & Forecast
        • 10.3.2.2.1. By Compounds
        • 10.3.2.2.2. By Application
        • 10.3.2.2.3. By Substances
        • 10.3.2.2.4. By Indication
        • 10.3.2.2.5. By Method
        • 10.3.2.2.6. By End-User
    • 10.3.3. UAE Stable Isotopes Labeled Compounds Market Outlook
      • 10.3.3.1. Market Size & Forecast
        • 10.3.3.1.1. By Value
      • 10.3.3.2. Market Share & Forecast
        • 10.3.3.2.1. By Compounds
        • 10.3.3.2.2. By Application
        • 10.3.3.2.3. By Substances
        • 10.3.3.2.4. By Indication
        • 10.3.3.2.5. By Method
        • 10.3.3.2.6. By End-User

11. Market Dynamics

  • 11.1. Drivers
  • 11.2. Challenges

12. Market Trends & Developments

  • 12.1. Mergers & Acquisitions
  • 12.2. Product Launches
  • 12.3. Technological Advancements

13. Competitive Landscape

  • 13.1. Business Overview
  • 13.2. Company Snapshot
  • 13.3. Products & Services
  • 13.4. Financials (As Reported)
  • 13.5. Recent Developments
  • 13.6. SWOT Analysis
    • 13.6.1. PerkinElmer Inc.
    • 13.6.2. Merck KGaA
    • 13.6.3. 3M Company
    • 13.6.4. Cambridge Isotope Laboratories, Inc.
    • 13.6.5. JSC Isotope
    • 13.6.6. Creative Proteomics
    • 13.6.7. Medical Isotopes, Inc.
    • 13.6.8. Omicron Biochemicals, Inc.
    • 13.6.9. Trace Sciences International
    • 13.6.10. Nippon Sanso Holdings Corporation

14. Strategic Recommendations