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市场调查报告书
商品编码
1691775
遗传性血管性水肿治疗市场 - 全球产业规模、份额、趋势、机会和预测,按药物类别、配销通路、应用、地区和竞争细分,2020-2030 年预测Hereditary Angioedema Therapeutics Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Drug Class, By Distribution Channel, By Application, By Region and Competition, 2020-2030F |
2024 年全球遗传性血管性水肿治疗市场价值为 43.6 亿美元,预计到 2030 年将达到 72.8 亿美元,复合年增长率为 8.89%。全球遗传性血管性水肿治疗市场正在经历显着扩张,这得益于人们认识的提高、诊断能力的提高以及新治疗方案的推出。基因研究的进步使得早期和准确的诊断成为可能,从而可以及时干预和更好地管理疾病。製药公司正专注于开发标靶疗法,包括单株抗体和小分子抑制剂,以提供长期预防和急性治疗解决方案。遗传性血管性水肿盛行率的不断上升,加上医疗支出的不断增加和患者权益保护的不断加强,进一步推动了市场的成长。此外,创新疗法的监管批准以及皮下和口服治疗方案的出现正在提高患者的依从性和便利性,为该行业创造了良好的前景。
市场概况 | |
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预测期 | 2026-2030 |
2024 年市场规模 | 43.6 亿美元 |
2030 年市场规模 | 72.8 亿美元 |
2025-2030 年复合年增长率 | 8.89% |
成长最快的领域 | 预防 |
最大的市场 | 北美洲 |
强大的新药通路和不断增加的研发投入正在塑造竞争格局。生物製药公司正在探索具有更高疗效、更少副作用和改进给药方法的下一代疗法。从静脉注射到皮下和口服治疗的转变正在改变护理标准,减轻患者和医疗保健提供者的负担。製药公司、研究机构和患者组织之间的合作和策略伙伴关係正在加速药物开发和市场渗透。随着越来越多的患者寻求预防措施而不是仅依赖急性治疗,预防性治疗的扩展预计将推动长期市场永续性。
研发方面的进步
治疗费用高昂
个人化医疗方法
Global Hereditary Angioedema Therapeutics Market was valued at USD 4.36 Billion in 2024 and is expected to reach USD 7.28 Billion in the forecast period with a CAGR of 8.89% through 2030. The global hereditary angioedema therapeutics market is experiencing significant expansion, driven by increasing awareness, improved diagnostic capabilities, and the introduction of novel treatment options. Advances in genetic research have enabled early and accurate diagnosis, allowing for timely intervention and better disease management. Pharmaceutical companies are focusing on developing targeted therapies, including monoclonal antibodies and small-molecule inhibitors, to provide long-term prophylaxis and acute treatment solutions. The growing prevalence of hereditary angioedema, coupled with rising healthcare expenditure and patient advocacy efforts, is further supporting market growth. Furthermore, regulatory approvals for innovative therapies and the emergence of subcutaneous and oral treatment options are enhancing patient adherence and convenience, creating a favorable outlook for the industry.
Market Overview | |
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Forecast Period | 2026-2030 |
Market Size 2024 | USD 4.36 Billion |
Market Size 2030 | USD 7.28 Billion |
CAGR 2025-2030 | 8.89% |
Fastest Growing Segment | Prophylaxis |
Largest Market | North America |
A strong pipeline of novel drugs and increased investment in research and development are shaping the competitive landscape. Biopharmaceutical companies are exploring next-generation therapies that offer enhanced efficacy, fewer side effects, and improved administration methods. The shift from intravenous to subcutaneous and oral treatments is transforming the standard of care, reducing the burden on patients and healthcare providers. Collaborations and strategic partnerships between pharmaceutical firms, research institutions, and patient organizations are accelerating drug development and market penetration. The expansion of prophylactic treatments is expected to drive long-term market sustainability, as more patients seek preventive measures rather than relying solely on acute treatments.
Key Market Drivers
Advancements in Research and Development (R&D)
Advancements in Research and Development (R&D) have been pivotal in boosting the Global Hereditary Angioedema Therapeutics Market. Hereditary Angioedema is a rare genetic disorder characterized by debilitating and unpredictable swelling episodes that can be life-threatening. In recent years, the relentless pursuit of scientific knowledge and innovative therapies has transformed the landscape of HAE treatment.
One of the most significant drivers of market growth has been the breakthrough discoveries in understanding the underlying mechanisms of HAE. Researchers have delved deep into the genetic and biochemical aspects of the disease, leading to a more precise understanding of how it develops and progresses. This increased knowledge has paved the way for the development of targeted therapies that are specifically designed to address the root causes of HAE.
Monoclonal antibodies, in particular, have emerged as a revolutionary approach in HAE therapeutics. These monoclonal antibodies, such as lanadelumab and ecallantide, have been engineered to specifically inhibit the activity of proteins like plasma kallikrein, which play a critical role in HAE attacks. This precision in drug design has proven highly effective in preventing and managing HAE episodes, providing patients with newfound hope and relief from the burden of their condition.
Key Market Challenges
High Treatment Costs
The High treatment costs have emerged as a significant obstacle hindering the growth and accessibility of the Global Hereditary Angioedema Therapeutics Market. HAE is a rare genetic disorder characterized by recurrent and potentially life-threatening swelling episodes. While advancements in therapeutics have improved the quality of life for HAE patients, the exorbitant cost of these treatments poses a considerable challenge. The prohibitively high cost of treatment makes these life-saving therapies inaccessible to a substantial portion of HAE patients, especially those without comprehensive health insurance coverage. This leads to disparities in access to care, with only a fraction of those in need benefiting from the latest advancements in HAE therapeutics.
For individuals who manage to access HAE therapies, the financial strain can be overwhelming. Copayments, deductibles, and out-of-pocket expenses can quickly accumulate, potentially forcing patients to make difficult choices between their healthcare needs and other essential expenses.
Access to HAE treatments is even more challenging in regions with limited healthcare resources and lower income levels. This exacerbates global healthcare disparities, where patients in wealthier nations have greater access to cutting-edge treatments, while those in less affluent regions struggle to secure even basic care.
Key Market Trends
Personalized Medicine Approaches
Hereditary angioedema (HAE) is a rare genetic disorder characterized by recurrent episodes of severe swelling in various body parts, including the extremities, face, gastrointestinal tract, and airway. This condition is caused by mutations in the SERPING1 gene, leading to deficient or dysfunctional C1 inhibitor (C1-INH) proteins, which play a crucial role in regulating inflammatory pathways.
Personalized medicine has significantly advanced the management of HAE by tailoring treatments to individual genetic profiles and disease manifestations. The process begins with precise genetic testing to identify specific mutations in the SERPING1 gene, which helps determine the subtype of HAE a patient has. This accurate diagnosis is essential, as it guides the selection of targeted therapies that address the underlying pathophysiological mechanisms.
For instance, patients with Type I HAE, characterized by low levels of functional C1-INH, may benefit from C1-INH replacement therapies such as Berinert or Cinryze. These treatments work by supplementing the deficient protein, thereby preventing or reducing the frequency of swelling episodes. Conversely, patients with normal C1-INH levels but dysfunctional protein (Type II HAE) might respond better to therapies that inhibit the kallikrein-kinin pathway, such as lanadelumab (Takhzyro), a monoclonal antibody that targets plasma kallikrein to prevent bradykinin formation, a key mediator of swelling in HAE.
In this report, the Global Hereditary Angioedema Therapeutics Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:
Company Profiles: Detailed analysis of the major companies present in the Global Hereditary Angioedema Therapeutics Market.
Global Hereditary Angioedema Therapeutics Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report: