下游加工市场－全球产业规模、份额、趋势、机会和预测，依产品、技术、应用、地区和竞争格局划分，2020-2030年预测

2024年全球下游加工市场规模为321亿美元，预计2030年将以6.79%的复合年增长率成长至476.1亿美元。全球下游加工市场涵盖了从复杂的生物基质中回收和纯化生物合成产品（主要是生物製药产品）的关键步骤，这些产品是在初始细胞培养或发酵之后获得的。这一重要的生物製造阶段旨在分离、纯化和浓缩所需的活性成分，以满足严格的品质和安全标准。市场成长的主要驱动力是全球对单株抗体和疫苗等先进生物製药产品的需求不断增长，以及生物技术领域研发投入的增加。

主要市场驱动因素

全球下游加工市场主要受到生物製药和生物製剂需求不断增长的推动。这些先进的治疗产品，包括单株抗体、疫苗和重组蛋白，对于应对日益广泛的慢性复杂疾病至关重要。

主要市场挑战

下游加工设备和耗材所需的高昂资本支出严重阻碍了全球市场的成长。这一资金壁垒限制了许多企业，尤其是新兴生物技术公司，投资于先进纯化和回收技术的能力。

主要市场趋势

数位化和自动化正在变革下游加工，提高效率，减少人为错误，并改善资料管理。这些进步实现了精确的製程控制、即时监控和自适应优化，从而提高了产品的一致性和产量。

目录

第一章：产品概述

第二章：研究方法

第三章：执行概要

第四章：顾客之声

第五章：全球下游加工市场展望

• 市场规模及预测
  • 按价值
• 市占率及预测
  • 副产品（色谱系统、过滤器、蒸发器、离心机、干燥器、其他）
  • 依技术（细胞破碎、固液分离、浓缩、层析纯化、製剂、其他）
  • 依应用领域（抗生素生产、荷尔蒙生产、抗体生产、酵素生产、疫苗生产、其他）
  • 按地区
  • 按公司（2024 年）
• 市场地图

第六章：北美下游加工市场展望

• 市场规模及预测
• 市占率及预测
• 北美洲：国家分析
  • 美国
  • 加拿大
  • 墨西哥

第七章：欧洲下游加工市场展望

• 市场规模及预测
• 市占率及预测
• 欧洲：国家分析
  • 德国
  • 法国
  • 英国
  • 义大利
  • 西班牙

第八章：亚太下游加工市场展望

• 市场规模及预测
• 市占率及预测
• 亚太地区：国家分析
  • 中国
  • 印度
  • 日本
  • 韩国
  • 澳洲

第九章：中东和非洲下游加工市场展望

• 市场规模及预测
• 市占率及预测
• 中东和非洲：国家分析
  • 沙乌地阿拉伯
  • 阿联酋
  • 南非

第十章：南美洲下游加工市场展望

• 市场规模及预测
• 市占率及预测
• 南美洲：国家分析
  • 巴西
  • 哥伦比亚
  • 阿根廷

第十一章：市场动态

• 司机
• 挑战

第十二章：市场趋势与发展

• 併购
• 产品发布
• 最新进展

第十三章：全球下游加工市场：SWOT分析

第十四章：波特五力分析

• 产业竞争
• 新进入者的潜力
• 供应商议价能力
• 顾客的力量
• 替代产品的威胁

第十五章：竞争格局

• Merck KGaA
• Sartorius AG
• GE HealthCare Technologies, Inc.
• Thermo Fisher Scientific Inc
• Danaher Corp.
• Repligen Corp.
• 3M Company
• Boehringer Ingelheim International GmbH
• Corning Inc.
• Lonza Group AG

第十六章：策略建议

第17章调查会社について・免责事项

The Global Downstream Processing Market, valued at USD 32.10 Billion in 2024, is projected to experience a CAGR of 6.79% to reach USD 47.61 Billion by 2030. The global downstream processing market encompasses the critical stages involved in the recovery and purification of biosynthetic products, primarily biopharmaceuticals, from complex biological matrices following initial cell culture or fermentation. This essential biomanufacturing phase aims to isolate, purify, and concentrate the desired active ingredients to meet stringent quality and safety standards. Market growth is principally supported by the increasing global demand for advanced biopharmaceutical products such as monoclonal antibodies and vaccines, coupled with rising research and development investments within the biotechnology sector.

Key Market Drivers

The Global Downstream Processing Market is significantly propelled by the escalating demand for biopharmaceuticals and biologics. These advanced therapeutic products, including monoclonal antibodies, vaccines, and recombinant proteins, are increasingly critical for addressing a widening spectrum of chronic and complex diseases. As research pipelines yield successful candidates and biologics achieve regulatory approval, the imperative for efficient, high-purity recovery and purification processes intensifies. This sustained demand necessitates robust downstream operations capable of managing expanded production volumes while adhering to stringent quality standards.

Key Market Challenges

The high capital expenditure required for essential downstream processing equipment and consumables presents a significant impediment to the growth of the global market. This financial barrier limits the ability of many organizations, particularly emerging biotechnology firms, to invest in advanced purification and recovery technologies. Consequently, this leads to delays in adopting modern bioprocessing solutions and restricts the expansion of manufacturing capacity necessary to meet increasing demand for biopharmaceutical products.

Key Market Trends

Digitalization and automation are transforming downstream processing, enhancing efficiency, minimizing human error, and improving data management. These advancements enable precise process control, real-time monitoring, and adaptive optimization, leading to increased consistency and yield. The ISPE's 7th Pharma 4.0(TM) Survey, released in 2023, revealed that organizations not yet initiating Pharma 4.0(TM) adoption decreased from 31.2% in 2021 to 15.1% in 2023, highlighting a significant industry shift towards digital transformation.

Key Market Players

• Merck KGaA
• Sartorius AG
• GE HealthCare Technologies, Inc.
• Thermo Fisher Scientific Inc
• Danaher Corp.
• Repligen Corp.
• 3M Company
• Boehringer Ingelheim International GmbH
• Corning Inc.
• Lonza Group AG

Report Scope:

In this report, the Global Downstream Processing Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

Downstream Processing Market, By Product:

• Chromatography Systems
• Filters
• Evaporators
• Centrifuges
• Dryers
• Others

Downstream Processing Market, By Technique:

• Cell Disruption
• Solid-liquid Separation
• Concentration
• Purification by Chromatography
• Formulation
• Others

Downstream Processing Market, By Application:

• Antibiotic Production
• Hormone Production
• Antibodies Production
• Enzyme Production
• Vaccine Production
• Others

Downstream Processing Market, By Region:

• North America
  • United States
  • Canada
  • Mexico
• Europe
  • France
  • United Kingdom
  • Italy
  • Germany
  • Spain
• Asia Pacific
  • China
  • India
  • Japan
  • Australia
  • South Korea
• South America
  • Brazil
  • Argentina
  • Colombia
• Middle East & Africa
  • South Africa
  • Saudi Arabia
  • UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies presents in the Global Downstream Processing Market.

Available Customizations:

Global Downstream Processing Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

• Detailed analysis and profiling of additional market players (up to five).

Table of Contents

1. Product Overview

• 1.1. Market Definition
• 1.2. Scope of the Market
  • 1.2.1. Markets Covered
  • 1.2.2. Years Considered for Study
  • 1.2.3. Key Market Segmentations

2. Research Methodology

• 2.1. Objective of the Study
• 2.2. Baseline Methodology
• 2.3. Key Industry Partners
• 2.4. Major Association and Secondary Sources
• 2.5. Forecasting Methodology
• 2.6. Data Triangulation & Validation
• 2.7. Assumptions and Limitations

3. Executive Summary

• 3.1. Overview of the Market
• 3.2. Overview of Key Market Segmentations
• 3.3. Overview of Key Market Players
• 3.4. Overview of Key Regions/Countries
• 3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global Downstream Processing Market Outlook

• 5.1. Market Size & Forecast
  • 5.1.1. By Value
• 5.2. Market Share & Forecast
  • 5.2.1. By Product (Chromatography Systems, Filters, Evaporators, Centrifuges, Dryers, Others)
  • 5.2.2. By Technique (Cell Disruption, Solid-liquid Separation, Concentration, Purification by Chromatography, Formulation, Others)
  • 5.2.3. By Application (Antibiotic Production, Hormone Production, Antibodies Production, Enzyme Production, Vaccine Production, Others)
  • 5.2.4. By Region
  • 5.2.5. By Company (2024)
• 5.3. Market Map

6. North America Downstream Processing Market Outlook

• 6.1. Market Size & Forecast
  • 6.1.1. By Value
• 6.2. Market Share & Forecast
  • 6.2.1. By Product
  • 6.2.2. By Technique
  • 6.2.3. By Application
  • 6.2.4. By Country
• 6.3. North America: Country Analysis
  • 6.3.1. United States Downstream Processing Market Outlook
    • 6.3.1.1. Market Size & Forecast
      • 6.3.1.1.1. By Value
    • 6.3.1.2. Market Share & Forecast
      • 6.3.1.2.1. By Product
      • 6.3.1.2.2. By Technique
      • 6.3.1.2.3. By Application
  • 6.3.2. Canada Downstream Processing Market Outlook
    • 6.3.2.1. Market Size & Forecast
      • 6.3.2.1.1. By Value
    • 6.3.2.2. Market Share & Forecast
      • 6.3.2.2.1. By Product
      • 6.3.2.2.2. By Technique
      • 6.3.2.2.3. By Application
  • 6.3.3. Mexico Downstream Processing Market Outlook
    • 6.3.3.1. Market Size & Forecast
      • 6.3.3.1.1. By Value
    • 6.3.3.2. Market Share & Forecast
      • 6.3.3.2.1. By Product
      • 6.3.3.2.2. By Technique
      • 6.3.3.2.3. By Application

7. Europe Downstream Processing Market Outlook

• 7.1. Market Size & Forecast
  • 7.1.1. By Value
• 7.2. Market Share & Forecast
  • 7.2.1. By Product
  • 7.2.2. By Technique
  • 7.2.3. By Application
  • 7.2.4. By Country
• 7.3. Europe: Country Analysis
  • 7.3.1. Germany Downstream Processing Market Outlook
    • 7.3.1.1. Market Size & Forecast
      • 7.3.1.1.1. By Value
    • 7.3.1.2. Market Share & Forecast
      • 7.3.1.2.1. By Product
      • 7.3.1.2.2. By Technique
      • 7.3.1.2.3. By Application
  • 7.3.2. France Downstream Processing Market Outlook
    • 7.3.2.1. Market Size & Forecast
      • 7.3.2.1.1. By Value
    • 7.3.2.2. Market Share & Forecast
      • 7.3.2.2.1. By Product
      • 7.3.2.2.2. By Technique
      • 7.3.2.2.3. By Application
  • 7.3.3. United Kingdom Downstream Processing Market Outlook
    • 7.3.3.1. Market Size & Forecast
      • 7.3.3.1.1. By Value
    • 7.3.3.2. Market Share & Forecast
      • 7.3.3.2.1. By Product
      • 7.3.3.2.2. By Technique
      • 7.3.3.2.3. By Application
  • 7.3.4. Italy Downstream Processing Market Outlook
    • 7.3.4.1. Market Size & Forecast
      • 7.3.4.1.1. By Value
    • 7.3.4.2. Market Share & Forecast
      • 7.3.4.2.1. By Product
      • 7.3.4.2.2. By Technique
      • 7.3.4.2.3. By Application
  • 7.3.5. Spain Downstream Processing Market Outlook
    • 7.3.5.1. Market Size & Forecast
      • 7.3.5.1.1. By Value
    • 7.3.5.2. Market Share & Forecast
      • 7.3.5.2.1. By Product
      • 7.3.5.2.2. By Technique
      • 7.3.5.2.3. By Application

8. Asia Pacific Downstream Processing Market Outlook

• 8.1. Market Size & Forecast
  • 8.1.1. By Value
• 8.2. Market Share & Forecast
  • 8.2.1. By Product
  • 8.2.2. By Technique
  • 8.2.3. By Application
  • 8.2.4. By Country
• 8.3. Asia Pacific: Country Analysis
  • 8.3.1. China Downstream Processing Market Outlook
    • 8.3.1.1. Market Size & Forecast
      • 8.3.1.1.1. By Value
    • 8.3.1.2. Market Share & Forecast
      • 8.3.1.2.1. By Product
      • 8.3.1.2.2. By Technique
      • 8.3.1.2.3. By Application
  • 8.3.2. India Downstream Processing Market Outlook
    • 8.3.2.1. Market Size & Forecast
      • 8.3.2.1.1. By Value
    • 8.3.2.2. Market Share & Forecast
      • 8.3.2.2.1. By Product
      • 8.3.2.2.2. By Technique
      • 8.3.2.2.3. By Application
  • 8.3.3. Japan Downstream Processing Market Outlook
    • 8.3.3.1. Market Size & Forecast
      • 8.3.3.1.1. By Value
    • 8.3.3.2. Market Share & Forecast
      • 8.3.3.2.1. By Product
      • 8.3.3.2.2. By Technique
      • 8.3.3.2.3. By Application
  • 8.3.4. South Korea Downstream Processing Market Outlook
    • 8.3.4.1. Market Size & Forecast
      • 8.3.4.1.1. By Value
    • 8.3.4.2. Market Share & Forecast
      • 8.3.4.2.1. By Product
      • 8.3.4.2.2. By Technique
      • 8.3.4.2.3. By Application
  • 8.3.5. Australia Downstream Processing Market Outlook
    • 8.3.5.1. Market Size & Forecast
      • 8.3.5.1.1. By Value
    • 8.3.5.2. Market Share & Forecast
      • 8.3.5.2.1. By Product
      • 8.3.5.2.2. By Technique
      • 8.3.5.2.3. By Application

9. Middle East & Africa Downstream Processing Market Outlook

• 9.1. Market Size & Forecast
  • 9.1.1. By Value
• 9.2. Market Share & Forecast
  • 9.2.1. By Product
  • 9.2.2. By Technique
  • 9.2.3. By Application
  • 9.2.4. By Country
• 9.3. Middle East & Africa: Country Analysis
  • 9.3.1. Saudi Arabia Downstream Processing Market Outlook
    • 9.3.1.1. Market Size & Forecast
      • 9.3.1.1.1. By Value
    • 9.3.1.2. Market Share & Forecast
      • 9.3.1.2.1. By Product
      • 9.3.1.2.2. By Technique
      • 9.3.1.2.3. By Application
  • 9.3.2. UAE Downstream Processing Market Outlook
    • 9.3.2.1. Market Size & Forecast
      • 9.3.2.1.1. By Value
    • 9.3.2.2. Market Share & Forecast
      • 9.3.2.2.1. By Product
      • 9.3.2.2.2. By Technique
      • 9.3.2.2.3. By Application
  • 9.3.3. South Africa Downstream Processing Market Outlook
    • 9.3.3.1. Market Size & Forecast
      • 9.3.3.1.1. By Value
    • 9.3.3.2. Market Share & Forecast
      • 9.3.3.2.1. By Product
      • 9.3.3.2.2. By Technique
      • 9.3.3.2.3. By Application

10. South America Downstream Processing Market Outlook

• 10.1. Market Size & Forecast
  • 10.1.1. By Value
• 10.2. Market Share & Forecast
  • 10.2.1. By Product
  • 10.2.2. By Technique
  • 10.2.3. By Application
  • 10.2.4. By Country
• 10.3. South America: Country Analysis
  • 10.3.1. Brazil Downstream Processing Market Outlook
    • 10.3.1.1. Market Size & Forecast
      • 10.3.1.1.1. By Value
    • 10.3.1.2. Market Share & Forecast
      • 10.3.1.2.1. By Product
      • 10.3.1.2.2. By Technique
      • 10.3.1.2.3. By Application
  • 10.3.2. Colombia Downstream Processing Market Outlook
    • 10.3.2.1. Market Size & Forecast
      • 10.3.2.1.1. By Value
    • 10.3.2.2. Market Share & Forecast
      • 10.3.2.2.1. By Product
      • 10.3.2.2.2. By Technique
      • 10.3.2.2.3. By Application
  • 10.3.3. Argentina Downstream Processing Market Outlook
    • 10.3.3.1. Market Size & Forecast
      • 10.3.3.1.1. By Value
    • 10.3.3.2. Market Share & Forecast
      • 10.3.3.2.1. By Product
      • 10.3.3.2.2. By Technique
      • 10.3.3.2.3. By Application

11. Market Dynamics

• 11.1. Drivers
• 11.2. Challenges

12. Market Trends & Developments

• 12.1. Merger & Acquisition (If Any)
• 12.2. Product Launches (If Any)
• 12.3. Recent Developments

13. Global Downstream Processing Market: SWOT Analysis

14. Porter's Five Forces Analysis

• 14.1. Competition in the Industry
• 14.2. Potential of New Entrants
• 14.3. Power of Suppliers
• 14.4. Power of Customers
• 14.5. Threat of Substitute Products

15. Competitive Landscape

• 15.1. Merck KGaA
  • 15.1.1. Business Overview
  • 15.1.2. Products & Services
  • 15.1.3. Recent Developments
  • 15.1.4. Key Personnel
  • 15.1.5. SWOT Analysis
• 15.2. Sartorius AG
• 15.3. GE HealthCare Technologies, Inc.
• 15.4. Thermo Fisher Scientific Inc
• 15.5. Danaher Corp.
• 15.6. Repligen Corp.
• 15.7. 3M Company
• 15.8. Boehringer Ingelheim International GmbH
• 15.9. Corning Inc.
• 15.10. Lonza Group AG

16. Strategic Recommendations

17. About Us & Disclaimer