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市场调查报告书
商品编码
1965409

结构生物学和分子建模技术市场－全球产业规模、份额、趋势、机会、预测：按工具、应用、地区和竞争对手划分，2021-2031年

Structural Biology & Molecular Modeling Techniques Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Tools, By Application, By Region & Competition, 2021-2031F
出版日期: | 出版商: TechSci Research | 英文 185 Pages | 商品交期: 2-3个工作天内

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简介目录

全球结构生物学和分子建模技术市场预计将从 2025 年的 27.6 亿美元大幅成长至 2031 年的 46.8 亿美元，复合年增长率为 9.21%。

该领域涵盖旨在阐明生物大分子三维结构的实验和计算方法。该市场的成长主要受治疗慢性疾病的新型疗法的巨大需求所驱动。精准的标靶分子鑑定对于降低临床试验的脱落率至关重要。此外，製药业为加速药物研发週期而进行的合理化药物设计策略转型，也是推动这些分析技术在药物发现过程中广泛应用的重要因素。

市场概览
预测期 2027-2031
市场规模：2025年 27.6亿美元
市场规模：2031年 46.8亿美元
复合年增长率：2026-2031年 9.21%
成长最快的细分市场 SaaS 与独立建模
最大的市场 北美洲

然而，高解析度设备（例如冷冻电镜）所需的大量资本投入限制了小规模研究机构进入市场，并阻碍了整个产业的扩张。全球蛋白质资料库的数据显示，2024年将有15,471个新的生物大分子结构发表，展现了该领域惊人的生产力。然而，产生和管理如此庞大的资料集所带来的高昂成本和技术复杂性，对那些资源有限的机构而言，是进入这一领域的巨大障碍。

市场驱动因素

人工智慧和机器学习演算法的快速普及正在从根本上改变全球结构生物学和分子建模技术市场，显着提升了聚合物结构预测的速度和准确性。这些计算技术的进步使研究人员能够绕过传统繁琐的实验方法，快速识别复杂蛋白质标靶上的潜在药物结合位点。这些人工智慧驱动技术的商业性价值在领先製药公司之间的合作中显而易见。例如，Isomorphic Labs于2024年1月与礼来公司达成合作，共同开发小分子治疗药物，其中Isomorphic Labs支付了4500万美元的预付款，潜在合约价值高达17亿美元，这充分体现了人工智慧在简化药物发现早期阶段的关键作用。

同时，全球慢性病和感染疾病率上升迫使製药业拓展其结构生物学业务，以加速治疗方案的研发。疾病日益复杂化，需要精准的分子建模来最大限度地减少脱靶效应并优化药物疗效。例如，世界卫生组织（WHO）报告称，2022年全球新增癌症病例约2000万例，死亡病例约970万例，凸显了研发新型癌症治疗方法的紧迫性。对高效药物研发解决方案的激增需求直接推动了技术提供商的财务成长，Schrödinger公司2024财年报告便印证了这一点，该报告显示其全年收入达2.167亿美元（同比增长19.7%）。

市场挑战

全球结构生物学和分子建模技术市场成长的一大障碍是高解析度设备所需的巨额资本投入。先进的分析工具，尤其是冷冻电镜，除了高昂的维护成本外，还需要数百万美元的初始投资。这一经济壁垒有效地将很大一部分潜在客户拒之门外，特别是资金有限的中小型生物技术公司和学术研究机构。因此，市场仍集中在资金雄厚的製药巨头手中，限制了这些关键药物研发技术的应用。

生命科学领域资金筹措环境的恶化加剧了这些经济限制因素，进一步限制了小规模企业购买资本密集硬体的能力。麻州生技委员会的数据显示，预计到2024年，生物製药公司的创业投资资金筹措轮数将降至222轮，年减。投资活动的减少表明，新兴企业优先考虑业务永续营运而非基础设施扩张，它们无法获得购买昂贵系统所需的资金，这直接限制了市场规模，减缓了结构生物学技术的整体商业性发展。

市场趋势

业界正经历着向云端原生和SaaS分子建模平台的变革性转变，这使得先进运算工具的获取更加普及，并减少了对昂贵的本地基础设施的依赖。生命科学机构正在加速向可扩展的云端环境迁移，以有效处理生物模拟和即时协作所需的大型资料集。这种转变使研究团队能够在优化营运成本的同时，加快先导化合物的优化，这一趋势也反映在领先供应商的财务表现上。例如，Certara报告称，受生物模拟技术需求的推动，其2024年第四季的软体收入达到4,230万美元，年增26%。

同时，混合结构测定调查方法的普及正在拓展市场能力，突破单一技术的限制。透过整合来自核磁共振（NMR）波谱、冷冻电镜和X射线晶体衍射等多种分析技术的数据，研究人员现在可以建立更全面的生物大分子动态模型。这种整合策略对于研究静态成像技术无法完全阐明的复杂蛋白质动力学至关重要，并推动了对配套测量仪器的持续投资。例如，布鲁克公司于2025年10月宣布，已获得价值约1,000万美元的先进NMR系统订单，以支持顶尖机构进行高影响力结构生物学研究。

目录

第一章概述

第二章：调查方法

第三章执行摘要

第四章：客户心声

第五章：结构生物学与分子建模技术的全球市场展望

  • 市场规模及预测
    • 按金额
  • 市占率及预测
    • 依工具分类（SaaS/独立建模工具、视觉化/分析工具、其他工具）
    • 按应用领域（药物开发、药物发现、其他）
    • 按地区
    • 按公司（2025 年）
  • 市场地图

第六章：北美结构生物学与分子建模技术市场展望

  • 市场规模及预测
  • 市占率及预测
  • 北美洲：国别分析
    • 我们
    • 加拿大
    • 墨西哥

第七章：欧洲结构生物学与分子建模技术市场展望

  • 市场规模及预测
  • 市占率及预测
  • 欧洲：国别分析
    • 德国
    • 法国
    • 英国
    • 义大利
    • 西班牙

第八章：亚太地区结构生物学与分子建模技术市场展望

  • 市场规模及预测
  • 市占率及预测
  • 亚太地区：国别分析
    • 中国
    • 印度
    • 日本
    • 韩国
    • 澳洲

第九章：中东和非洲结构生物学和分子建模技术市场展望

  • 市场规模及预测
  • 市占率及预测
  • 中东与非洲：国别分析
    • 沙乌地阿拉伯
    • 阿拉伯聯合大公国
    • 南非

第十章：南美洲结构生物学与分子建模技术市场展望

  • 市场规模及预测
  • 市占率及预测
  • 南美洲：国别分析
    • 巴西
    • 哥伦比亚
    • 阿根廷

第十一章 市场动态

  • 促进因素
  • 任务

第十二章 市场趋势与发展

  • 併购
  • 产品发布
  • 近期趋势

第十三章：全球结构生物学与分子建模技术市场：SWOT分析

第十四章：波特五力分析

  • 产业竞争
  • 新进入者的潜力
  • 供应商的议价能力
  • 顾客权力
  • 替代品的威胁

第十五章 竞争格局

  • Charles River System Inc.
  • Acellera Ltd
  • Agile Molecule
  • Agilent Technologies Inc.
  • Biomax Informatics AG
  • Bruker Corporation
  • Chemical Computing Group
  • Dassault Systemes
  • Illumina Inc.
  • ThermoFisher Scientific Inc

第十六章 策略建议

第十七章：关于研究公司及免责声明

简介目录
Product Code: 23478

The Global Structural Biology & Molecular Modeling Techniques Market is projected to expand significantly, growing from USD 2.76 Billion in 2025 to USD 4.68 Billion by 2031 at a CAGR of 9.21%. This sector encompasses both experimental and computational methodologies designed to decipher the three-dimensional architecture of biological macromolecules. The market is primarily propelled by the critical demand for novel therapeutics to address chronic diseases, which requires precise target identification to mitigate clinical attrition rates. Furthermore, the pharmaceutical industry's strategic pivot toward rational drug design to accelerate development cycles serves as a key catalyst for the widespread adoption of these analytical technologies throughout drug discovery pipelines.

Market Overview
Forecast Period2027-2031
Market Size 2025USD 2.76 Billion
Market Size 2031USD 4.68 Billion
CAGR 2026-20319.21%
Fastest Growing SegmentSaaS and Standalone Modeling
Largest MarketNorth America

However, the substantial capital expenditure required for high-resolution instrumentation, such as cryo-electron microscopes, restricts market access for smaller research entities and hinders broader industry expansion. Data from the Worldwide Protein Data Bank indicates that 15,471 new biological macromolecular structures were released in 2024, demonstrating the sector's immense productivity. Despite this output, the exorbitant costs and technical intricacies associated with generating and managing such vast datasets present significant barriers for resource-constrained organizations attempting to establish a foothold in this specialized field.

Market Driver

The rapid assimilation of AI and machine learning algorithms is fundamentally transforming the Global Structural Biology & Molecular Modeling Techniques Market by drastically enhancing the speed and accuracy of macromolecular structure prediction. These computational advancements allow researchers to bypass traditional, time-intensive experimental methods, facilitating the quick identification of druggable pockets on complex protein targets. The commercial significance of these AI-driven capabilities is highlighted by major pharmaceutical alliances, such as Isomorphic Labs' January 2024 partnership with Lilly to discover small molecule therapeutics, which involved a $45 million upfront payment and a potential deal value reaching $1.7 billion, confirming AI's indispensable role in streamlining early-stage discovery.

Concurrently, the rising global incidence of chronic and infectious diseases is compelling the pharmaceutical sector to scale its structural biology operations to hasten therapeutic development. The growing prevalence of complex conditions necessitates precise molecular modeling to minimize off-target effects and optimize drug efficacy. For instance, the World Health Organization reported approximately 20 million new cancer cases and 9.7 million deaths globally in 2022, underscoring the urgent need for novel oncology treatments. This surge in demand for effective drug design solutions is directly fueling financial growth for technology providers, as evidenced by Schrodinger's February 2024 report showing a 19.7% increase in full-year revenue to $216.7 million.

Market Challenge

A major impediment to the growth of the Global Structural Biology & Molecular Modeling Techniques Market is the immense capital investment required for high-resolution instrumentation. Advanced analytical tools, particularly cryo-electron microscopes, necessitate multimillion-dollar initial outlays alongside high ongoing maintenance costs. This financial barrier effectively excludes a large segment of the potential customer base, specifically small-to-medium biotechnology firms and academic laboratories with limited endowments. As a result, the market remains heavily concentrated among well-funded pharmaceutical giants, restricting the widespread deployment of these critical drug discovery technologies.

This economic constraint is exacerbated by a tightening financing environment within the life sciences sector, which further limits the ability of smaller entities to procure capital-intensive hardware. Data from the Massachusetts Biotechnology Council reveals that the total number of venture capital funding rounds for biopharmaceutical companies declined to 222 in 2024, marking a reduction from the previous year. This contraction in investment activity suggests that emerging organizations are prioritizing operational survival over infrastructure expansion, and their inability to secure necessary funding for expensive systems directly stifles market volume and slows the overall commercial development of structural biology techniques.

Market Trends

The industry is witnessing a transformative shift toward Cloud-Native and SaaS-Based Molecular Modeling Platforms, which is democratizing access to advanced computational tools and reducing reliance on expensive on-premise infrastructure. Life sciences organizations are increasingly migrating to scalable cloud environments that facilitate real-time collaboration and the efficient handling of massive datasets required for biosimulation. This transition allows research teams to accelerate lead optimization while optimizing operational expenditures, a trend reflected in the financial performance of key providers; for example, Certara reported a 26% year-over-year increase in software revenue to $42.3 million in the fourth quarter of 2024, driven by the demand for its biosimulation technologies.

In parallel, the Proliferation of Hybrid Structural Determination Methodologies is expanding the market's capabilities beyond the limitations of individual techniques. By integrating data from diverse analytical approaches such as Nuclear Magnetic Resonance (NMR) spectroscopy, cryo-electron microscopy, and X-ray crystallography, researchers can construct more comprehensive dynamic models of biological macromolecules. This integrative strategy is critical for studying complex protein dynamics that static imaging methods cannot fully resolve, promoting continued investment in complementary instrumentation. Illustrating this trend, Bruker announced in October 2025 that it secured orders valued at approximately $10 million for advanced NMR systems to support high-impact structural biology research across leading institutions.

Key Market Players

  • Charles River System Inc.
  • Acellera Ltd
  • Agile Molecule
  • Agilent Technologies Inc.
  • Biomax Informatics AG
  • Bruker Corporation
  • Chemical Computing Group
  • Dassault Systemes
  • Illumina Inc.
  • ThermoFisher Scientific Inc

Report Scope

In this report, the Global Structural Biology & Molecular Modeling Techniques Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

Structural Biology & Molecular Modeling Techniques Market, By Tools

  • SaaS and Standalone Modeling
  • Visualization and Analysis
  • Other Tools

Structural Biology & Molecular Modeling Techniques Market, By Application

  • Drug Development
  • Drug Discovery
  • Others

Structural Biology & Molecular Modeling Techniques Market, By Region

  • North America
    • United States
    • Canada
    • Mexico
  • Europe
    • France
    • United Kingdom
    • Italy
    • Germany
    • Spain
  • Asia Pacific
    • China
    • India
    • Japan
    • Australia
    • South Korea
  • South America
    • Brazil
    • Argentina
    • Colombia
  • Middle East & Africa
    • South Africa
    • Saudi Arabia
    • UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Structural Biology & Molecular Modeling Techniques Market.

Available Customizations:

Global Structural Biology & Molecular Modeling Techniques Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

  • Detailed analysis and profiling of additional market players (up to five).

Table of Contents

1. Product Overview

  • 1.1. Market Definition
  • 1.2. Scope of the Market
    • 1.2.1. Markets Covered
    • 1.2.2. Years Considered for Study
    • 1.2.3. Key Market Segmentations

2. Research Methodology

  • 2.1. Objective of the Study
  • 2.2. Baseline Methodology
  • 2.3. Key Industry Partners
  • 2.4. Major Association and Secondary Sources
  • 2.5. Forecasting Methodology
  • 2.6. Data Triangulation & Validation
  • 2.7. Assumptions and Limitations

3. Executive Summary

  • 3.1. Overview of the Market
  • 3.2. Overview of Key Market Segmentations
  • 3.3. Overview of Key Market Players
  • 3.4. Overview of Key Regions/Countries
  • 3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global Structural Biology & Molecular Modeling Techniques Market Outlook

  • 5.1. Market Size & Forecast
    • 5.1.1. By Value
  • 5.2. Market Share & Forecast
    • 5.2.1. By Tools (SaaS and Standalone Modeling, Visualization and Analysis, Other Tools)
    • 5.2.2. By Application (Drug Development, Drug Discovery, Others)
    • 5.2.3. By Region
    • 5.2.4. By Company (2025)
  • 5.3. Market Map

6. North America Structural Biology & Molecular Modeling Techniques Market Outlook

  • 6.1. Market Size & Forecast
    • 6.1.1. By Value
  • 6.2. Market Share & Forecast
    • 6.2.1. By Tools
    • 6.2.2. By Application
    • 6.2.3. By Country
  • 6.3. North America: Country Analysis
    • 6.3.1. United States Structural Biology & Molecular Modeling Techniques Market Outlook
      • 6.3.1.1. Market Size & Forecast
        • 6.3.1.1.1. By Value
      • 6.3.1.2. Market Share & Forecast
        • 6.3.1.2.1. By Tools
        • 6.3.1.2.2. By Application
    • 6.3.2. Canada Structural Biology & Molecular Modeling Techniques Market Outlook
      • 6.3.2.1. Market Size & Forecast
        • 6.3.2.1.1. By Value
      • 6.3.2.2. Market Share & Forecast
        • 6.3.2.2.1. By Tools
        • 6.3.2.2.2. By Application
    • 6.3.3. Mexico Structural Biology & Molecular Modeling Techniques Market Outlook
      • 6.3.3.1. Market Size & Forecast
        • 6.3.3.1.1. By Value
      • 6.3.3.2. Market Share & Forecast
        • 6.3.3.2.1. By Tools
        • 6.3.3.2.2. By Application

7. Europe Structural Biology & Molecular Modeling Techniques Market Outlook

  • 7.1. Market Size & Forecast
    • 7.1.1. By Value
  • 7.2. Market Share & Forecast
    • 7.2.1. By Tools
    • 7.2.2. By Application
    • 7.2.3. By Country
  • 7.3. Europe: Country Analysis
    • 7.3.1. Germany Structural Biology & Molecular Modeling Techniques Market Outlook
      • 7.3.1.1. Market Size & Forecast
        • 7.3.1.1.1. By Value
      • 7.3.1.2. Market Share & Forecast
        • 7.3.1.2.1. By Tools
        • 7.3.1.2.2. By Application
    • 7.3.2. France Structural Biology & Molecular Modeling Techniques Market Outlook
      • 7.3.2.1. Market Size & Forecast
        • 7.3.2.1.1. By Value
      • 7.3.2.2. Market Share & Forecast
        • 7.3.2.2.1. By Tools
        • 7.3.2.2.2. By Application
    • 7.3.3. United Kingdom Structural Biology & Molecular Modeling Techniques Market Outlook
      • 7.3.3.1. Market Size & Forecast
        • 7.3.3.1.1. By Value
      • 7.3.3.2. Market Share & Forecast
        • 7.3.3.2.1. By Tools
        • 7.3.3.2.2. By Application
    • 7.3.4. Italy Structural Biology & Molecular Modeling Techniques Market Outlook
      • 7.3.4.1. Market Size & Forecast
        • 7.3.4.1.1. By Value
      • 7.3.4.2. Market Share & Forecast
        • 7.3.4.2.1. By Tools
        • 7.3.4.2.2. By Application
    • 7.3.5. Spain Structural Biology & Molecular Modeling Techniques Market Outlook
      • 7.3.5.1. Market Size & Forecast
        • 7.3.5.1.1. By Value
      • 7.3.5.2. Market Share & Forecast
        • 7.3.5.2.1. By Tools
        • 7.3.5.2.2. By Application

8. Asia Pacific Structural Biology & Molecular Modeling Techniques Market Outlook

  • 8.1. Market Size & Forecast
    • 8.1.1. By Value
  • 8.2. Market Share & Forecast
    • 8.2.1. By Tools
    • 8.2.2. By Application
    • 8.2.3. By Country
  • 8.3. Asia Pacific: Country Analysis
    • 8.3.1. China Structural Biology & Molecular Modeling Techniques Market Outlook
      • 8.3.1.1. Market Size & Forecast
        • 8.3.1.1.1. By Value
      • 8.3.1.2. Market Share & Forecast
        • 8.3.1.2.1. By Tools
        • 8.3.1.2.2. By Application
    • 8.3.2. India Structural Biology & Molecular Modeling Techniques Market Outlook
      • 8.3.2.1. Market Size & Forecast
        • 8.3.2.1.1. By Value
      • 8.3.2.2. Market Share & Forecast
        • 8.3.2.2.1. By Tools
        • 8.3.2.2.2. By Application
    • 8.3.3. Japan Structural Biology & Molecular Modeling Techniques Market Outlook
      • 8.3.3.1. Market Size & Forecast
        • 8.3.3.1.1. By Value
      • 8.3.3.2. Market Share & Forecast
        • 8.3.3.2.1. By Tools
        • 8.3.3.2.2. By Application
    • 8.3.4. South Korea Structural Biology & Molecular Modeling Techniques Market Outlook
      • 8.3.4.1. Market Size & Forecast
        • 8.3.4.1.1. By Value
      • 8.3.4.2. Market Share & Forecast
        • 8.3.4.2.1. By Tools
        • 8.3.4.2.2. By Application
    • 8.3.5. Australia Structural Biology & Molecular Modeling Techniques Market Outlook
      • 8.3.5.1. Market Size & Forecast
        • 8.3.5.1.1. By Value
      • 8.3.5.2. Market Share & Forecast
        • 8.3.5.2.1. By Tools
        • 8.3.5.2.2. By Application

9. Middle East & Africa Structural Biology & Molecular Modeling Techniques Market Outlook

  • 9.1. Market Size & Forecast
    • 9.1.1. By Value
  • 9.2. Market Share & Forecast
    • 9.2.1. By Tools
    • 9.2.2. By Application
    • 9.2.3. By Country
  • 9.3. Middle East & Africa: Country Analysis
    • 9.3.1. Saudi Arabia Structural Biology & Molecular Modeling Techniques Market Outlook
      • 9.3.1.1. Market Size & Forecast
        • 9.3.1.1.1. By Value
      • 9.3.1.2. Market Share & Forecast
        • 9.3.1.2.1. By Tools
        • 9.3.1.2.2. By Application
    • 9.3.2. UAE Structural Biology & Molecular Modeling Techniques Market Outlook
      • 9.3.2.1. Market Size & Forecast
        • 9.3.2.1.1. By Value
      • 9.3.2.2. Market Share & Forecast
        • 9.3.2.2.1. By Tools
        • 9.3.2.2.2. By Application
    • 9.3.3. South Africa Structural Biology & Molecular Modeling Techniques Market Outlook
      • 9.3.3.1. Market Size & Forecast
        • 9.3.3.1.1. By Value
      • 9.3.3.2. Market Share & Forecast
        • 9.3.3.2.1. By Tools
        • 9.3.3.2.2. By Application

10. South America Structural Biology & Molecular Modeling Techniques Market Outlook

  • 10.1. Market Size & Forecast
    • 10.1.1. By Value
  • 10.2. Market Share & Forecast
    • 10.2.1. By Tools
    • 10.2.2. By Application
    • 10.2.3. By Country
  • 10.3. South America: Country Analysis
    • 10.3.1. Brazil Structural Biology & Molecular Modeling Techniques Market Outlook
      • 10.3.1.1. Market Size & Forecast
        • 10.3.1.1.1. By Value
      • 10.3.1.2. Market Share & Forecast
        • 10.3.1.2.1. By Tools
        • 10.3.1.2.2. By Application
    • 10.3.2. Colombia Structural Biology & Molecular Modeling Techniques Market Outlook
      • 10.3.2.1. Market Size & Forecast
        • 10.3.2.1.1. By Value
      • 10.3.2.2. Market Share & Forecast
        • 10.3.2.2.1. By Tools
        • 10.3.2.2.2. By Application
    • 10.3.3. Argentina Structural Biology & Molecular Modeling Techniques Market Outlook
      • 10.3.3.1. Market Size & Forecast
        • 10.3.3.1.1. By Value
      • 10.3.3.2. Market Share & Forecast
        • 10.3.3.2.1. By Tools
        • 10.3.3.2.2. By Application

11. Market Dynamics

  • 11.1. Drivers
  • 11.2. Challenges

12. Market Trends & Developments

  • 12.1. Merger & Acquisition (If Any)
  • 12.2. Product Launches (If Any)
  • 12.3. Recent Developments

13. Global Structural Biology & Molecular Modeling Techniques Market: SWOT Analysis

14. Porter's Five Forces Analysis

  • 14.1. Competition in the Industry
  • 14.2. Potential of New Entrants
  • 14.3. Power of Suppliers
  • 14.4. Power of Customers
  • 14.5. Threat of Substitute Products

15. Competitive Landscape

  • 15.1. Charles River System Inc.
    • 15.1.1. Business Overview
    • 15.1.2. Products & Services
    • 15.1.3. Recent Developments
    • 15.1.4. Key Personnel
    • 15.1.5. SWOT Analysis
  • 15.2. Acellera Ltd
  • 15.3. Agile Molecule
  • 15.4. Agilent Technologies Inc.
  • 15.5. Biomax Informatics AG
  • 15.6. Bruker Corporation
  • 15.7. Chemical Computing Group
  • 15.8. Dassault Systemes
  • 15.9. Illumina Inc.
  • 15.10. ThermoFisher Scientific Inc

16. Strategic Recommendations

17. About Us & Disclaimer