一次性生物反应器市场规模（按地区、范围和预测）

一次性生物反应器的市场规模及预测

2023 年一次性生物反应器市场规模价值为 43.7 亿美元，预计到 2031 年将达到 179 亿美元，2024 年至 2031 年的复合年增长率为 19.26%。一次性生物反应器市场是指生物加工产业的一个部分，专注于开发、製造和利用用于各种生物製药和生物技术应用的一次性生物反应器系统。这些系统旨在为细胞生长、发酵和蛋白质表现等细胞培养过程提供高效、经济的解决方案，同时最大限度地减少对传统不銹钢生物反应器的需求。

一次性生物反应器的全球市场动态

主要市场驱动因子

对生物製剂的需求不断增加：

全球对治疗和管理各种慢性疾病有效的生物製剂和生物相似药的需求激增是一次性生物反应器市场的主要驱动力。这些反应器为生物製剂製造提供了一种经济高效、多功能且更快捷的解决方案，以满足日益增长的医药产品需求。

成本效益高，降低污染风险：

一次性生物反应器减少了对先进无菌技术的需求和交叉污染的风险，这对于製药生产至关重要。它的一次性特性减少了清洁、维护和停机成本，使其成为组织经济可行的选择。

灵活性和可扩充性：

一次性生物反应器不需要大规模的资本投入，并且用途广泛，可以适应从中试到商业生产的广泛生产规模，这推动了它们的应用。这种适应性满足了生物製药研发的动态需求，实现了快速的营运扩展，并加速了产品上市。

技术进步与监管支援：

生物反应器设计、材料和感测器技术的不断发展正在提高生物过程的效率和控制。监管机构批准一次性系统用于临床和商业製造，确保符合行业标准，从而促进市场成长。

主要问题：

废弃物管理与环境问题：

一次性生物反应器的处理会因产生塑胶废弃物而造成严重的环境问题。这些废弃物很难得到负责任的管理，并且会抑制市场需求，因为它与製药和生物技术行业对环境永续性的日益关注相衝突。

规模限制：

一次性生物反应器在某些生产规模下具有灵活性和成本效益，但在大规模生物製造方面具有局限性。由于需要较大的容量，一次性系统变得不切实际，并限制其在大容量生物过程中的使用。

材料相容性与可萃取物：

一次性生物反应器中使用的材料必须与多种生物过程相容，并且不会与产品产生不利的相互作用。可能污染生物製剂的可浸出物和可萃取物对维持产品纯度和安全性构成了重大障碍，限制了该行业的扩张。

主要趋势：

扩展到细胞和基因治疗：

随着细胞和基因疗法成为主流治疗方法，一次性生物反应器在细胞和基因疗法生产中的应用越来越多。它的高适应性和低污染风险使其成为这些药物所需的精确和敏感的製造过程的理想选择。

我们对永续发展的承诺：

出于对环境问题的考虑，创建更永续的一次性生物反应器系统的运动日益增多。这些努力包括回收旧材料、减少一次性物品的碳足迹、开发可生物降解或环保的替代品以减少对环境的影响。

客製化和可扩充性解决方案：

开发人员专注于提供客製化解决方案，以满足您独特的製造需求，从小规模研发到大规模商业生产。这种可自订和可扩展的一次性生物反应器设定的趋势满足了生物製药公司的不同需求并实现了广泛的应用。

目录

第 1 章简介

• 市场定义
• 市场区隔
• 研究方法

第 2 章执行摘要

• 主要发现 市场概况 市集亮点

第3章 市场概览

• 市场规模与成长潜力
• 市场趋势
• 市场推动因素
• 市场限制
• 市场机会
• 波特五力分析

第 4 章一次性生物反应器市场（按生物反应器类型划分）

• 搅拌槽生物反应器
• 波混合生物反应器
• 气泡塔生物反应器

第 5 章一次性生物反应器市场（按细胞类型）

• 哺乳动物细胞
• 微生物细胞
• 酵母细胞

第6章 一次性生物反应器市场（按应用）

• 单株抗体生产
• 疫苗製造
• 基因治疗
• 干细胞培养
• 生物加工

第 7 章 区域分析

• 北美洲
• 美国
• 加拿大
• 墨西哥
• 欧洲
• 英国
• 德国
• 法国
• 义大利 亚太地区
• 中国
• 日本
• 印度
• 澳大利亚
• 拉丁美洲
• 巴西
• 阿根廷
• 智利
• 中东和非洲
• 南非
• 沙乌地阿拉伯
• 阿拉伯联合大公国

第 8 章 市场动态

• 市场推动因素
• 市场限制
• 市场机会
• COVID-19 市场影响

第 9 章 竞争格局

• 大型公司
• 市占率分析

第10章 公司简介

• Sartorius AG
• Danaher Corporation
• Thermo Fisher Scientific Inc
• Merck KGaA
• Eppendorf AG
• Getinge AB
• CESCO BIOENGINEERING CO LTD
• Applikon Biotechnology
• PBS Biotech Inc
• Distek Inc
• Celltainer

第 11 章 市场展望与机会

• 新兴技术
• 未来市场趋势
• 投资机会

第 12 章附录

• 缩写列表
• 来源与参考文献

Single-Use Bioreactors Market Size And Forecast

Single-use Bioreactors Market size was valued at USD 4.37 Billion in 2023 and is projected to reach USD 17.9 Billion by 2031, growing at a CAGR of 19.26% from 2024 to 2031. The Single-use Bioreactors Market refers to the segment within the bioprocessing industry that focuses on the development, manufacturing, and utilization of single-use bioreactor systems for various biopharmaceutical and biotechnology applications. These systems are designed to provide efficient and cost-effective solutions for cell culture processes, including cell growth, fermentation, and protein expression, while minimizing the need for traditional stainless steel bioreactors.

Global Single-Use Bioreactors Market Dynamics

The key market dynamics that are shaping the single-use bioreactors market include:

Key Market Drivers

Increasing Demand for Biologics:

The global spike in demand for biologics and biosimilars, which are effective in treating and managing a variety of chronic diseases, is a major driver of the single-use bioreactors market. These reactors provide a cost-effective, versatile, and speedier solution for biologics manufacturing, meeting the growing need for medicinal pharmaceuticals.

Cost Efficiency and Lower Contamination Risks:

Single-use bioreactors decrease the need for sophisticated sterilization techniques and the risk of cross-contamination, which is critical in pharmaceutical manufacturing. Their disposability results in cost savings on cleaning, maintenance, and downtime, making them an economically viable option for organizations.

Flexibility and Scalability:

The versatility of single-use bioreactors to various production sizes, from pilot to commercial, without requiring major capital investment, drives their application. This adaptability meets the dynamic needs of biopharmaceutical research and development, enabling quick scaling of operations and propelling market growth.

Technological Advancements and Regulatory Support:

Continuous developments in bioreactor design, materials, and sensor technology improve bioprocess efficiency and control. The approval of single-use systems for clinical and commercial manufacturing by regulatory organizations contributing to market growth by assuring compliance with industry standards.

Key Challenges:

Waste Management and Environmental Concerns:

The disposability of single-use bioreactors presents serious environmental problems due to the production of plastic trash. This waste is difficult to manage responsibly because it contradicts the pharmaceutical and biotech industries' growing emphasis on environmental sustainability, inhibiting the market demand.

Limitations in Scale:

While single-use bioreactors are flexible and cost-effective for particular scales of production, they have limitations when it comes to large-scale biomanufacturing. The requirement for bigger volumes makes single-use systems less practicable, potentially limiting their use in high-volume biologic processes.

Material Compatibility and Leachables:

The materials used in single-use bioreactors must be suitable with a wide range of bioprocesses and have no unfavorable interactions with the product. The concerning leachables and extractables that could contaminate biologic goods present significant hurdles to maintaining product purity and safety, limiting industry expansion.

Key Trends:

Expansion into Cell and Gene Therapies:

Single-use bioreactors are being used more and more in the manufacturing of cell and gene therapies as they become mainstream medical treatments. Their adaptability and low contamination risk make them perfect for the precise and sensitive manufacturing processes required by these medicines.

Sustainability Initiatives:

In response to environmental concerns, there is a rising movement to create more sustainable single-use bioreactor systems. This involves attempts to recycle used materials, minimize the carbon footprint of disposables, and develop biodegradable or eco-friendly alternatives that aim to lessen environmental effects.

Customization and Scalability Solutions:

Manufacturers are focusing on delivering customized solutions that meet unique manufacturing requirements, ranging from small-scale research and development to large-scale commercial production. This trend towards customizable and scalable single-use bioreactor setups meets the different needs of biopharmaceutical firms, enabling a wide range of applications.

Global Single-use Bioreactors Market Regional Analysis

Here is a more detailed regional analysis of the single-use bioreactors Market:

North America:

According to Verified Market Research, North America is estimated to dominate in single-use bioreactors market over the forecast period. North America, particularly the United States, has a thriving and advanced biopharmaceutical industry that leads in biologics and vaccine production. This industry's strength provides a sizable client base for single-use bioreactors, promoting their usage in flexible, cost-effective, and efficient biomanufacturing processes.

The region's strong investment in R&D, which is supported by both the commercial and public sectors, drives innovation in bioprocessing technology. This investment promotes the use of single-use bioreactors, which are essential for the development and production of next-generation biopharmaceuticals.

The strict regulatory framework in North America, which focuses on product safety and manufacturing efficiency, promotes the usage of single-use bioreactors. These systems provide advantages in terms of compliance, reduced contamination risk, and scalability, while also meeting regulatory agencies' quality assurance standards for pharmaceutical manufacturing.

Furthermore, North America has been at the forefront of introducing new technology into biomanufacturing, such as single-use bioreactors. The region's openness to embrace innovation promotes operational efficiencies, shorter production timelines, and cheaper prices, cementing its dominance in the global market for single-use bioreactors.

Asia Pacific:

The biopharmaceutical industry in the Asia Pacific is growing quickly, fueled by a rise in investments in biotech startups and the regional growth of multinational pharmaceutical corporations. This expansion increases demand for single-use bioreactors, which provide flexibility and efficiency in biologics production.

Many nations in the Asia Pacific are enacting supporting laws and providing funds to grow their biotech industry. Government attempts to improve healthcare infrastructure, promote R&D, and attract foreign investment all contribute to the growing need for single-use bioreactors.

Furthermore, the region's huge and ageing population, combined with expanding healthcare awareness and expenditure, is driving up demand for biopharmaceuticals. Single-use bioreactors, which are essential for the quick manufacture of vaccines and biologics, are increasingly being used to address these healthcare demands efficiently.

Europe:

Europe is experiencing tremendous investment in biopharmaceutical research and development from both the public and private sectors. This funding promotes innovation in bioprocessing technologies, such as single-use bioreactors, thereby facilitating their application in the development and manufacturing of improved medicinal solutions.

European regulatory organizations have backed innovative manufacturing technologies that promise to improve product quality and safety. This regulatory environment pushes pharmaceutical companies to deploy single-use bioreactor systems, which increase sterility and reduce contamination risk while adhering to regulatory requirements.

Furthermore, the increased emphasis on sustainability and decreasing environmental footprints in European manufacturing promotes the usage of single-use bioreactors. Despite waste concerns, the overall environmental impact is offset through lower energy and water consumption, which is consistent with the region's sustainability goals.

Global Single-Use Bioreactors Market Segmentation Analysis

The Single-use Bioreactors Market is segmented based on Product, Cell, Molecule, End-User, And Geography.

Single-use Bioreactors Market, By Product

• Bioreactor Systems
• Media Bags
• Filtration Assemblies
• Others

Based on Product, the market is segmented into Bioreactor Systems, Media Bags, Filtration Assemblies and Others. The bioreactor systems segment is estimated to dominate the single-use bioreactors market due to the critical role that these systems play in cell culture and biopharmaceutical synthesis. Single-use bioreactor systems provide substantial benefits, such as reduced contamination risk, lower initial investment, and shorter batch turnaround times, which are especially useful in the fast-paced pharmaceutical and biotech sectors. Their scalability and flexibility make them appropriate for a wide range of applications, from small-scale R&D to large-scale commercial manufacturing.

Single-use Bioreactors Market, By Cell

• Mammalian Cell
• Bacteria
• Yeast
• Others

Based on Cell, the market is segmented into Mammalian Cells, Bacteria, Yeast and Others. The mammalian cell segment is estimated to dominate the single-use bioreactors market due to the important role mammalian cells play in the synthesis of complex biologics such as monoclonal antibodies, vaccines, and recombinant proteins. These cells are critical for expressing proteins with appropriate folding, assembly, and post-translational modifications, which are required for therapeutic efficacy and safety.

Single-use Bioreactors Market, By Molecule

• Vaccines
• Monoclonal Antibodies
• Stem Cells
• Recombinant Proteins
• Others

Based on Molecule, the market is segmented into Vaccines, Monoclonal Antibodies, Stem Cells, Recombinant Proteins and Others. The vaccines segment is estimated to dominate the single-use bioreactors market owing to the global emphasis on immunization programmes and the rapid development of vaccines, as evidenced by the urgent manufacture of the COVID-19 vaccine. Single-use bioreactors provide significant benefits for vaccine production, including increased flexibility in scaling operations, a lower risk of cross-contamination, and faster turnaround times for vaccine development and manufacturing.

Single-use Bioreactors Market, By End-User

• Pharmaceutical & Biopharmaceutical Industries
• Contract Research Organizations (CRO)
• Others

Based on End-User, the market is divided into Pharmaceutical & Biopharmaceutical Industries, Contract Research Organizations (CROs) and Others. The pharmaceutical & biopharmaceutical industries segment is estimated to dominate the market over the forecast period. This dominance is due to the substantial role these industries play in biopharmaceutical research, development, and manufacture, which includes vaccines, monoclonal antibodies, and other biologics. The rising frequency of chronic diseases and the desire for personalized medicine have contributed to an increase in the use of single-use bioreactors.

Single-use Bioreactors Market, By Geography

• North America
• Europe
• Asia Pacific
• Rest of the world

Based on Geography, the single-use bioreactors market is classified into North America, Europe, Asia Pacific, and the Rest of the world. North America is expected to dominate the single-use bioreactors market during the forecast period. North America, particularly the United States, has a highly developed biopharmaceutical sector that is at the forefront of biologics and vaccine invention and production worldwide. This thriving industry generates enormous demand for single-use bioreactors, which are critical for the efficient and adaptable manufacturing procedures required by modern biopharmaceutical production.

Key Players

• The "Single-use Bioreactors Market" study report will provide valuable insight with an emphasis on the global market. The major players in the market are
• Thermo Fisher Scientific, Merck KGaA, Danaher Corporation, Sartorius Stedim Biotech, GE Healthcare, Eppendorf AG, Inovenio, MilliporeSigma, XCell Biotek, PBS Biotech, HYCON Bruggemann GmbH, Dolomite Bio, Applikon Biotechnology, Boehringer Ingelheim, Lonza Group Ltd and Samsung Biologics.

Our market analysis also entails a section solely dedicated to such major players wherein our analysts provide an insight into the financial statements of all the major players, along with product benchmarking and SWOT analysis. The competitive landscape section also includes key development strategies, market share, and market ranking analysis of the above-mentioned players globally.

• Single-use Bioreactors Market Recent Developments
• In November 2022, Sartorius AG, a major participant in the region from Germany, announced plans to broaden its operations. To better meet the needs of the biopharmaceutical industry, this expansion comprises the establishment of new R&D laboratories as well as the implementation of equipment automation and digitization.
• In November 2022, Danaher Corporation's subsidiary Cytiva invested roughly USD 8 million to expand its Fast Trak centre in Shanghai, China. The expansion seeks to promote the adoption of single-use technologies (SUT) in the region and facilitate the industry's transition to single-use bioprocessing solutions.

TABLE OF CONTENTS

1. Introduction

• Market Definition
• Market Segmentation
• Research Methodology

2. Executive Summary

• Key Findings
• Market Overview
• Market Highlights

3. Market Overview

• Market Size and Growth Potential
• Market Trends
• Market Drivers
• Market Restraints
• Market Opportunities
• Porter's Five Forces Analysis

4. Single-Use Bioreactors Market, By Type of Bioreactor

• Stirred-Tank Bioreactors
• Wave-Mixed Bioreactors
• Bubble Column Bioreactors

5. Single-Use Bioreactors Market, By Cell Type

• Mammalian Cells
• Microbial Cells
• Yeast Cells

6. Single-Use Bioreactors Market, By Application

• Monoclonal Antibody Production
• Vaccine Manufacturing
• Gene Therapy
• Stem Cell Culture
• Bioprocessing

7. Regional Analysis

• North America
• United States
• Canada
• Mexico
• Europe
• United Kingdom
• Germany
• France
• Italy
• Asia-Pacific
• China
• Japan
• India
• Australia
• Latin America
• Brazil
• Argentina
• Chile
• Middle East and Africa
• South Africa
• Saudi Arabia
• UAE

8. Market Dynamics

• Market Drivers
• Market Restraints
• Market Opportunities
• Impact of COVID-19 on the Market

9. Competitive Landscape

• Key Players
• Market Share Analysis

10. Company Profiles

• Sartorius AG
• Danaher Corporation
• Thermo Fisher Scientific Inc
• Merck KGaA
• Eppendorf AG
• Getinge AB
• CESCO BIOENGINEERING CO LTD
• Applikon Biotechnology
• PBS Biotech Inc
• Distek Inc
• Celltainer

11. Market Outlook and Opportunities

• Emerging Technologies
• Future Market Trends
• Investment Opportunities

12. Appendix

• List of Abbreviations
• Sources and References