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市场调查报告书
商品编码
1738595
全球Baclofen市场规模(按类型、应用、区域范围和预测)Global Baclofen Market Size By Type (Tablet 10mg, Tablet 20mg), By Application (Hospital Pharmacy, Retail Pharmacy), By Geographic Scope And Forecast |
过去几年,Baclofen市场规模一直以显着的速度成长,预计在市场估计和预测期(2026-2032 年)内将大幅成长。
全球Baclofen市场的发展受到医疗保健产业对痉挛及相关疼痛、阵挛和肌肉僵硬治疗意识日益增强的推动。此外,政府对肌肉僵硬研究的资助也加速了该目标市场的成长。此外,鞘内帮浦(将药物直接输送至脊髓液,无需先经过消化器官系统和循环系统)对Baclofen的应用日益增多,也推动了市场的成长。全球Baclofen市场报告提供了市场的整体评估,全面分析了关键细分市场、趋势、市场驱动因素、限制因素、竞争格局以及影响市场的关键因素。
Baclofen的全球市场定义
Baclofen是一种白色至灰白色结晶质粉末,分子量为213.66 g/mol。其化学名称为4-氨基-3-(4-氯苯基)丁酸。它用于治疗多发性硬化症的痉挛症状,尤其是痉挛及相关的疼痛、阵挛和肌肉僵硬。Baclofen可以单独使用,也可以与其他药物合併使用。Baclofen有锭剂、混悬液和乳膏等外用剂型。它在水中溶解度适中,在甲醇中微溶,在氯仿中不溶。Baclofen透过活化GABAB受体来发挥作用,这与苯丁酸(另一种活化该受体并具有部分相同作用的药物)类似。
临近生命终点的打嗝和肌肉痉挛也可以用Baclofen治疗。它可以口服或直接注射到脊椎。在治疗肌肉痉挛方面,它作为 GABA-B 受体的选择性 GABA促效剂。它以 Lioresel 的名称出售,也有用于控制疼痛的局部乳膏剂型。它有锭剂、混悬液和乳膏状外用剂型。Baclofen可在医院药局、零售药局和网路药局购买。Baclofen也用于治疗酒精相关疾病,儘管 2018 年发表的一项综合评论发现,将其用作一线治疗的证据仍不清楚。
嗜睡、头晕、虚弱、疲劳、头痛、睡眠困难、噁心和呕吐是Baclofen的一些副作用。Baclofen以锭剂或液体形式口服。Baclofen用于治疗0-18岁儿童的症状性脑痉挛,特别适用于脑性麻痹儿童、脑血管意外后儿童以及肿瘤性或退化性脑疾病儿童。这两种剂型之间存在生物等效性。
液体製剂可能对幼儿和无法耐受锭剂的患者特别有益。使用液体製剂,可以更精确地调整剂量。建议使用符合最佳疗效的最低剂量。在开始Baclofen治疗之前,建议对患者的整体临床病程进行现实的分析。谨慎调整剂量直至病情稳定非常重要,尤其是老年人。初始剂量过大或过快增加剂量可能会导致副作用。
全球Baclofen市场概览
Baclofen在治疗痉挛性运动障碍(尤其是脊髓损伤、脑性麻痹和多发性硬化症)的应用日益增多,这推动了Baclofen市场的未来成长。随着各国政府加大对医疗产业肌肉僵硬研究的投入,预计市场将进一步扩大。此外,Baclofen广泛用于治疗各种神经系统疾病,这也推动了市场的成长。Baclofen可能透过使传入神经末梢超极化来抑制脊髓层面的单突触反射和多突触反射。
因此,全球Baclofen市场的成长轨迹得到了支撑。Baclofen越来越多地用于鞘内泵,这种泵将药物直接输送到脊髓液中,而无需先经过消化器官系统和循环系统,从而推动了市场的成长。Baclofen最近被探索用于酒精戒断治疗,但在这种情况下的有效性尚无定论。美国环保署 (EPA) 于 2018 年核准使用Baclofen治疗酒精成瘾,但仅限于所有其他治疗方法均无效的情况下。
此外,Baclofen在治疗各种神经系统疾病方面的应用日益普及,以及政府在医疗保健行业支出的增加,预计将在未来促进市场发展。然而,Baclofen的副作用,例如虚弱、疲劳、头痛、失眠、噁心/呕吐、闭尿症滞留和便秘,预计将限制市场扩张。呕吐、全身疲倦、嗜睡、呼吸衰竭、癫痫、瞳孔大小异常、头晕、头痛、高血压、反射减弱、昏迷甚至死亡都是Baclofen过量摄取的征兆。预计这方面也将在未来几年限制Baclofen市场的发展。
Baclofen Market size is growing at a faster pace with substantial growth rates over the last few years and is estimated that the market will grow significantly in the forecasted period i.e. 2026 to 2032.
The Global Baclofen Market is being driven by rising awareness regarding spasms and accompanying pain, clonus, and muscular rigidity treatment in the health care industry. Furthermore, government funding in muscle stiffness research is accelerating the target market's growth. Furthermore, the increasing use of Baclofen in Intrathecal pumps, which carry the drug straight to the spinal fluid rather than passing through the digestive and circulatory systems first, is boosting the market's growth. The Global Baclofen Market report provides a holistic evaluation of the market. The report offers a comprehensive analysis of key segments, trends, drivers, restraints, competitive landscape, and factors that are playing a substantial role in the market.
Global Baclofen Market Definition
Baclofen is a crystalline powder that is white to off-white in color and has a molecular weight of 213.66 g/mol. Its chemical name is 4-amino-3-(4-chlorophenyl) butanoic acid. It's used to treat the symptoms of multiple sclerosis spasticity, particularly spasms and associated pain, clonus, and muscular rigidity. It can be used alone or in combination with other drugs. Baclofen is available in tablet, suspension, and topical cream base forms. Water is moderately soluble, methanol is somewhat soluble, and chloroform is insoluble. Baclofen works by activating the GABAB receptor, which is similar to phenibut, another medicine that activates this receptor and has some of the same effects.
Hiccups and muscle spasms near the end of life can also be treated with Baclofen. It is administered either orally or directly into the spinal canal. In the treatment of muscle spasticity, it acts as a GABA agonist that is selective for GABA-B receptors. It's marketed as Lioresel, and it's also found in topical cream formulations for pain control. It comes in pill, suspension, and topical cream base forms. Baclofen is available in hospital pharmacies, retail pharmacies, and online pharmacies. Baclofen has also been used to treat alcohol-related disorders, but according to a comprehensive review published in 2018, the evidence for its usage as a first-line medication is still equivocal.
Drowsiness, dizziness, weakness, exhaustion, headache, difficulty sleeping, nausea, and vomiting are some of the side effects of Baclofen. Baclofen is taken orally as a pill or a liquid. Baclofen is used to treat symptomatic cerebral spasticity in children aged 0 to 18, particularly in cases of infantile cerebral palsy, as well as after cerebrovascular events and in the setting of neoplastic or degenerative brain illness. Bioequivalence exists between these two formulations.
The liquid may be especially beneficial for youngsters or individuals who cannot consume tablets. With the liquid, dosage titration may be regulated more precisely. The lowest dose possible while yet achieving an optimal response is suggested. Before commencing baclofen treatment, it's a good idea to analyze the patient's overall clinical progress realistically. It is critical to carefully titrate the dosage (especially in the elderly) until the illness is stabilized. Side effects may develop if a high dose is started or if the dose is raised too quickly.
Global Baclofen Market Overview
The growing usage of Baclofen for the treatment of spastic movement disorders, particularly in cases of spinal cord injury, cerebral palsy, and multiple sclerosis has fueled the Baclofen Market's prospective growth. The market is predicted to increase as the government invests more in muscular stiffness research in the health care industry. Furthermore, baclofen is widely used to treat a variety of nervous system problems, which has fueled the market expansion. Baclofen inhibits both monosynaptic and polysynaptic reflexes at the spinal level, probably by afferent terminal hyperpolarization.
As a result, the Global Baclofen Market's growth curve is being supported. Baclofen is increasingly being used in Intrathecal pumps, which carry the medication straight to the spinal fluid rather than passing through the digestive and circulatory systems first, boosting the market's growth. Baclofen has lately been examined for the treatment of alcohol withdrawal, but no conclusions have been reached about its efficacy in this situation. The EPA granted baclofen marketing authorization for use in alcoholism therapy in 2018, but only if all other therapies had failed.
Furthermore, the expanding acceptance of Baclofen for the treatment of various nervous system illnesses, as well as increased government expenditure in the health care industry, are likely to provide profitable prospects for the market in the future years. However, Baclofen's side effects, such as weakness, exhaustion, headache, difficulty sleeping, nausea and vomiting, urine retention, or constipation, are predicted to limit market expansion. Vomiting, general weakness, drowsiness, respiratory insufficiency, seizures, atypical pupil size, dizziness, headaches, hypertension, hyporeflexia, coma, and death are all signs of a Baclofen overdose. In the approaching years, this aspect is also predicted to limit the Baclofen Market.
The Global Baclofen Market is segmented on the basis of Type, Application, And Geography.
Based on Type, The market is bifurcated into Tablet 10mg and Tablet 20mg. The market is dominated by the Tablet 10mg segment. This is owing to baclofen's standard dosage of 100 mg per day for adults and 60 mg per day for children aged 8 and up, for whom a 20 mg pill is most commonly used. Symptom control is usually satisfactory with doses up to 60 mg per day, although careful modification is often required to fit the needs of each sufferer.
Based on Application, The market is bifurcated into Hospital Pharmacy, Retail Pharmacy, and Online Pharma. The Retail Pharmacy segment has the biggest market share among the following segments. This is because if you have a doctor's prescription, you can buy baclofen at any local drugstore to deal with emergency medical circumstances.
The "Global Baclofen Market" study report will provide valuable insight with an emphasis on the global market. The major players in the market are LGM Pharma, Lannett, Beijing 4A Biotech, Novartis Pharma Schweiz, North Star Rx, Par Pharmaceuticals, Qualitest Products, Teva Pharmaceuticals. The competitive landscape section also includes key development strategies, market share, and market ranking analysis of the above-mentioned players globally.