单细胞样品製备市场-全球及区域分析:依应用、按区域-分析与预测(2025-2035)
市场调查报告书
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1808106

单细胞样品製备市场-全球及区域分析:依应用、按区域-分析与预测(2025-2035)

Single Cell Sample Preparation Market - A Global and Regional Analysis: Focus on Application, Country, and Region - Analysis and Forecast, 2025-2035

出版日期: | 出版商: BIS Research | 英文 100 Pages | 商品交期: 1-5个工作天内

价格

全球单细胞样本製备市场 - 分析与预测(2025-2035)

单细胞样品製备是一个关键过程,其中从较大的生物样品中分离并准备单个细胞以进行进一步分析。

这个过程使研究人员能够研究细胞群体内的异质性,从而对细胞行为、基因表现和疾病机制提供前所未有的洞察水平。

製备通常涉及多个步骤,包括使用微流体或液滴系统等方法分离细胞,然后进行裂解或保存以捕获RNA、DNA和蛋白质等分子内容物。在某些情况下,也会扩增遗传物质,并应用特定标记进行进一步分析。最终,该过程支持单细胞RNA序列测定等技术,使研究人员能够在单细胞层级上探索基因表现。

单细胞样品製备市场的主要驱动力之一是慢性疾病(尤其是癌症、糖尿病和神经系统疾病)的盛行率不断上升。这些疾病通常表现出显着的细胞异质性,传统的批量分析不足以揭示疾病机制并开发有效的治疗方法。单细胞分析技术使研究人员能够分析异质群体中的单一细胞,从而深入了解基因表现、蛋白质水平和细胞行为。

这种能力对于识别稀有细胞类型、了解肿瘤微环境以及发现新的治疗标靶至关重要。随着全球慢性病发病率持续上升,对单细胞分析工具和样本製备技术的需求预计将持续增长,从而促进精准医疗和个人化治疗的进步。

单细胞样品製备市场面临的主要挑战之一是每个细胞的起始样品量有限,这会在下游分析中引入技术噪音和扩增偏差。单一细胞中核酸含量极少,通常为皮克级,因此难以取得足够的样本进行全面分析。

为了克服这个局限性,人们采用了扩增技术。然而,这些方法往往会引入偏差,例如缺失事件(低丰度转录物无法检测到)以及过度扩增(可能扭曲基因表现)。这些挑战会影响单细胞分析的准确性和可重复性,尤其是在处理复杂组织或稀有细胞群体时。

全球单细胞样品製备市场竞争激烈,多家主要企业主要企业创新和市场成长。 10x Genomics、赛默飞世尔科技、Illumina、Becton, Dickinson and Company、Bio-Rad Laboratories、默克、诺禾致源、Lexogen 和 Standard BioTools(Fluidigm Corporation)等关键参与者在单细胞分析技术和解决方案方面处于领先地位。

这些公司不断创新,为单细胞研究提供更有效率、更精确、更可扩展的解决方案,从而解锁细胞洞察力。

单细胞样本製备市场区隔

细分一:按应用

  • 癌症研究
  • 神经病学
  • 免疫学
  • 干细胞生物学

细分2:按地区

  • 北美洲
  • 欧洲
  • 亚太地区

全球单细胞样本製备市场最重要的新兴趋势之一是单细胞多组体学整合的进步,整合单一细胞内各个分子层的数据,如转录组学、蛋白质组学、表观基因和代谢体学,以全面了解细胞功能和异质性。

整合多组学资料可以阐明复杂的生物过程和疾病机制,而这些是单分子层分析无法揭示的。这一趋势正在推动样品製备技术的创新,并促使开发新的方法和技术,以便有效地获取和处理单细胞多组学数据。

本报告研究了全球单细胞样品製备市场,概述了市场以及应用领域、区域趋势和公司概况。

目录

执行摘要

第一章全球单细胞样本製备市场:产业展望

  • 介绍
  • 市场趋势
  • 法律规范
  • 临床试验分析
  • 市场动态

2. 全球单细胞样本製备市场(依应用),2024-2035

  • 癌症研究
  • 神经病学
  • 免疫学
  • 干细胞生物学

3. 2024-2035 年全球单细胞样本製备市场(按地区)

  • 北美洲
  • 欧洲
  • 亚太地区

4. 全球单细胞样本製备市场:竞争格局与公司概况

  • 关键策略和发展
  • 公司简介
    • 10x Genomics
    • Thermo Fisher Scientific Inc.
    • Illumina, Inc.
    • Becton, Dickinson and Company
    • Bio-Rad Laboratories, Inc.
    • Merck KGaA
    • Novogene Co., Ltd.
    • Lexogen
    • Standard BioTools (Fluidigm Corporation)

第五章调查方法

Product Code: BHL3235SA

Global Single Cell Sample Preparation Market, Analysis and Forecast: 2025-2035

Single-cell sample preparation is a critical process that involves isolating and preparing individual cells from a larger biological sample for detailed analysis. This process allows researchers to study the heterogeneity within cell populations, providing insights into cellular behaviour, gene expression, and disease mechanisms at an unprecedented level of detail.

The preparation typically involves several stages, including isolating the cells using methods like microfluidics or droplet-based systems, followed by cell lysis or preservation to capture their molecular contents, such as RNA, DNA, or proteins. In some cases, the genetic material is amplified, and specific markers are applied for further analysis. Ultimately, this process enables technologies like single-cell RNA sequencing, allowing researchers to explore gene expression at the single-cell level, which is crucial for understanding complex biological systems and diseases, such as cancer and neurological disorders.

One of the key drivers of the single-cell sample preparation market is the increasing prevalence of chronic diseases, particularly cancer, diabetes, and neurological disorders. These conditions often exhibit significant cellular heterogeneity, making traditional bulk analysis insufficient for understanding disease mechanisms and developing effective treatments. Single-cell analysis technologies enable researchers to examine individual cells within a heterogeneous population, providing detailed insights into gene expression, protein levels, and cellular behaviour.

This capability is crucial for identifying rare cell types, understanding tumour microenvironments, and discovering novel therapeutic targets. As the incidence of chronic diseases continues to rise globally, the demand for single-cell analysis tools and sample preparation techniques is expected to grow, driving advancements in precision medicine and personalized therapies.

One of the primary challenges in the single-cell sample preparation market is the limited amount of starting material per cell, which leads to technical noise and amplification biases during downstream analyses. Each individual cell contains a minuscule quantity of nucleic acids typically in the range of picograms making it difficult to obtain sufficient material for comprehensive analysis.

To overcome this limitation, amplification techniques are employed; however, these methods often introduce biases such as dropout events, where low-abundance transcripts fail to be detected, and over-amplification, which can skew gene expression profiles. These challenges compromise the accuracy and reproducibility of single-cell analyses, particularly in complex tissues or when dealing with rare cell populations.

The global Single Cell Sample Preparation market is highly competitive, with several key players driving innovation and market growth. Leading companies such as 10x Genomics, Thermo Fisher Scientific Inc., Illumina, Inc., Becton, Dickinson and Company, Bio-Rad Laboratories, Inc., Merck KGaA, Novogene Co., Ltd., Lexogen, and Standard BioTools (Fluidigm Corporation) are at the forefront of advancing technologies and solutions in single-cell analysis.

These companies are continuously innovating to provide more efficient, precise, and scalable solutions for single-cell research, helping to unlock insights into cellular

Single Cell Sample Preparation Market Segmentation:

Segmentation 1: by Application

  • Cancer Research
  • Neurology
  • Immunology
  • Stem Cell Biology

Segmentation 2: by Region

  • North America
  • Europe
  • Asia-Pacific

One of the most significant emerging trends in the global single-cell sample preparation market is the advancement of single-cell multi-omics integration. This approach combines data from various molecular layers such as transcriptomics, proteomics, epigenomics, and metabolomics within individual cells to provide a comprehensive understanding of cellular functions and heterogeneity.

By integrating multiple omic data types, researchers can uncover complex biological processes and disease mechanisms that are not apparent when analyzing a single molecular layer alone. This trend is driving innovation in sample preparation techniques, necessitating the development of new methodologies and technologies to efficiently capture and process multi-omic data from single cells.

Table of Contents

Executive Summary

Scope and Definition

Market/Product Definition

Inclusion and Exclusion

Key Questions Answered

Analysis and Forecast Note

1. Global Single Cell Sample Preparation Market: Industry Outlook

  • 1.1 Introduction
  • 1.2 Market Trends
  • 1.3 Regulatory Framework
  • 1.4 Clinical Trial Analysis
  • 1.5 Market Dynamics
    • 1.5.1 Impact Analysis
    • 1.5.2 Market Drivers
    • 1.5.3 Market Challenges
    • 1.5.4 Market Opportunities

2. Global Single Cell Sample Preparation Market (by Application), ($Billion), 2024-2035

  • 2.1 Cancer Research
  • 2.2 Neurology
  • 2.3 Immunology
  • 2.4 Stem Cell Biology

3. Global Single Cell Sample Preparation Market (by Region), ($Billion), 2024-2035

  • 3.1 North America
    • 3.1.1 Key Findings
    • 3.1.2 Market Dynamics
    • 3.1.3 Market Sizing and Forecast
      • 3.1.3.1 North America Single Cell Sample Preparation Market, by Country
        • 3.1.3.1.1 U.S.
  • 3.2 Europe
    • 3.2.1 Key Findings
    • 3.2.2 Market Dynamics
    • 3.2.3 Market Sizing and Forecast
      • 3.2.3.1 Europe Single Cell Sample Preparation Market, by Country
        • 3.2.3.1.1 Germany
        • 3.2.3.1.2 U.K.
        • 3.2.3.1.3 France
        • 3.2.3.1.4 Italy
  • 3.3 Asia Pacific
    • 3.3.1 Key Findings
    • 3.3.2 Market Dynamics
    • 3.3.3 Market Sizing and Forecast
      • 3.3.3.1 Asia Pacific Single Cell Sample Preparation Market, by Country
        • 3.3.3.1.1 China
        • 3.3.3.1.2 Japan

4. Global Single Cell Sample Preparation Market: Competitive Landscape and Company Profiles

  • 4.1 Key Strategies and Development
    • 4.1.1 Mergers and Acquisitions
    • 4.1.2 Synergistic Activities
    • 4.1.3 Business Expansions and Funding
    • 4.1.4 Product Launches and Approvals
    • 4.1.5 Other Activities
  • 4.2 Company Profiles
    • 4.2.1 10x Genomics
      • 4.2.1.1 Overview
      • 4.2.1.2 Top Products / Product Portfolio
      • 4.2.1.3 Top Competitors
      • 4.2.1.4 Target Customers/End-Users
      • 4.2.1.5 Key Personnel
      • 4.2.1.6 Analyst View
    • 4.2.2 Thermo Fisher Scientific Inc.
      • 4.2.2.1 Overview
      • 4.2.2.2 Top Products / Product Portfolio
      • 4.2.2.3 Top Competitors
      • 4.2.2.4 Target Customers/End-Users
      • 4.2.2.5 Key Personnel
      • 4.2.2.6 Analyst View
    • 4.2.3 Illumina, Inc.
      • 4.2.3.1 Overview
      • 4.2.3.2 Top Products / Product Portfolio
      • 4.2.3.3 Top Competitors
      • 4.2.3.4 Target Customers/End-Users
      • 4.2.3.5 Key Personnel
      • 4.2.3.6 Analyst View
    • 4.2.4 Becton, Dickinson and Company
      • 4.2.4.1 Overview
      • 4.2.4.2 Top Products / Product Portfolio
      • 4.2.4.3 Top Competitors
      • 4.2.4.4 Target Customers/End-Users
      • 4.2.4.5 Key Personnel
      • 4.2.4.6 Analyst View
    • 4.2.5 Bio-Rad Laboratories, Inc.
      • 4.2.5.1 Overview
      • 4.2.5.2 Top Products / Product Portfolio
      • 4.2.5.3 Top Competitors
      • 4.2.5.4 Target Customers/End-Users
      • 4.2.5.5 Key Personnel
      • 4.2.5.6 Analyst View
    • 4.2.6 Merck KGaA
      • 4.2.6.1 Overview
      • 4.2.6.2 Top Products / Product Portfolio
      • 4.2.6.3 Top Competitors
      • 4.2.6.4 Target Customers/End-Users
      • 4.2.6.5 Key Personnel
      • 4.2.6.6 Analyst View
    • 4.2.7 Novogene Co., Ltd.
      • 4.2.7.1 Overview
      • 4.2.7.2 Top Products / Product Portfolio
      • 4.2.7.3 Top Competitors
      • 4.2.7.4 Target Customers/End-Users
      • 4.2.7.5 Key Personnel
      • 4.2.7.6 Analyst View
    • 4.2.8 Lexogen
      • 4.2.8.1 Overview
      • 4.2.8.2 Top Products / Product Portfolio
      • 4.2.8.3 Top Competitors
      • 4.2.8.4 Target Customers/End-Users
      • 4.2.8.5 Key Personnel
      • 4.2.8.6 Analyst View
    • 4.2.9 Standard BioTools (Fluidigm Corporation)
      • 4.2.9.1 Overview
      • 4.2.9.2 Top Products / Product Portfolio
      • 4.2.9.3 Top Competitors
      • 4.2.9.4 Target Customers/End-Users
      • 4.2.9.5 Key Personnel
      • 4.2.9.6 Analyst View

5. Research Methodology

List of Figures

  • Figure: Global Single Cell Sample Preparation Market (by Application), $Billion, 2024 and 2035
  • Figure: Global Single Cell Sample Preparation Market (by Region), $Billion, 2024 and 2035
  • Figure: Global Single Cell Sample Preparation Market Key Trends, Analysis

List of Tables

  • Table: Global Single Cell Sample Preparation Market Dynamics, Impact Analysis
  • Table: Global Single Cell Sample Preparation Market (by Region), $Billion, 2024-2035