下游加工市场：按技术、按产品、按应用、按最终用户、按地区

2024年全球下游加工市场规模预计为261.1亿美元，预计2031年将达771亿美元，2024年至2031年复合年增长率为16.7%。

图 1. 2024 年下游加工市场占有率(%)，依地区划分

下游加工是指发酵后发生的生物加工中的精製和回收步骤，以从细胞生物质或发酵液中分离出所需的活性成分或产物。这包括澄清以去除细胞碎片和成分、浓缩以减少减重并分离和回收所需产物，以及使用层析法技术的最终精製。下游加工在确保生物製药的纯度、品质和稳定性以及决定其在市场上的成功方面发挥关键作用。澄清和精製技术的进步，例如膨胀床层析法分离和连续处理，使得提高产品产量和吞吐量并降低产品成本成为可能。

市场动态：

生物製药行业的快速成长、生技药品优于小分子药物的偏好以及对单株抗体和疫苗的强劲需求推动了下游加工市场的成长。然而，与下游精製设备和操作相关的高成本阻碍了他们的发展。新兴市场连续製造和一次性技术的开拓为市场提供了开发整合和模组化流程创新解决方案的重大机会。市场领导正专注于合作伙伴关係和併购活动，以加强其精製解决方案和层析法树脂的产品组合。

本研究的主要特点

• 本报告对全球下游加工市场进行了详细分析，并提出了以2023年为基准年的预测期（2024-2031）的市场规模和年复合成长率（CAGR%）。
• 它还阐明了各个细分市场的潜在商机，并解释了该市场中有吸引力的投资提案的矩阵。
• 它还提供了有关市场驱动因素、限制因素、机会、新产品发布和核准、市场趋势、区域前景、主要企业采取的竞争策略等的重要见解。
• 它根据公司亮点、产品系列、主要亮点、财务表现和策略等参数，介绍了全球下游加工市场的主要企业。
• 该报告的见解使负责人和公司经营团队能够就未来的产品发布、类型升级、市场扩张和行销策略做出明智的决策。
• 本研究报告针对该产业的各个相关人员，如投资者、供应商、产品製造商、经销商、新进业者和财务分析师。
• 透过用于全球下游工艺市场分析的各种策略矩阵，将促进相关人员做出决策。

目录

第一章 研究目的与前提

• 研究目标
• 先决条件
• 简称

第二章 市场展望

• 报告说明
  • 市场定义和范围
• 执行概述
• 一致的机会地图 (COM)

第三章市场动态、法规及趋势分析

• 市场动态
  • 促进因素
  • 抑制因素
  • 机会
• 影响分析
• 市场趋势
• 监管场景
• 收购和合作场景
• 资金筹措和投资
• PEST分析
• 波特的分析

第四章全球下游製程市场－冠状病毒 (COVID-19) 大流行的影响

• 整体影响
• 政府倡议
• COVID-19 对市场的影响

第五章 全球下游製程市场，依技术划分，2019-2031 年（十亿美元）

• 介绍
• 净化技术
• 固液分离
• 澄清/浓缩

第六章 全球下游加工市场（按产品），2019-2031 年（十亿美元）

• 介绍
• 层析管柱和树脂
• 筛选
• 蒸发器
• 离心机
• 其他的

第七章 2019-2031 年全球下游製程市场（按应用）（十亿美元）

• 介绍
• 抗体产生
• 疫苗生产
• 胰岛素产生
• 其他的

第 8 章 2019-2031 年全球下游製程市场（按地区）（十亿美元）

• 介绍
• 拉丁美洲
• 欧洲
• 亚太地区
• 中东

第9章 竞争格局

• 公司简介
  • Merck KGaA
  • Thermo Fisher Scientific Inc.
  • GE Healthcare
  • Sartorius Stedim Biotech SA
  • Repligen Corporation
  • Pall Corporation
  • M Company
  • Eppendorf AG
  • Agilent Technologies, Inc.
  • Waters Corporation
  • Shimadzu Corporation
  • Bio-Rad Laboratories, Inc.
  • Avantor Performance Materials, LLC
  • Tosoh Corporation
  • Column Technology Inc.
  • Purolite
  • WR Grace &Co.
  • Asahi Kasei Corporation
  • Novasep Holding SAS
  • Boehringer Ingelheim

第10章分析师建议

• 升起和降落
• 综合机会图

第十一章 参考文献与调查方法

• 参考
• 调查方法

The Global Downstream Processing Market is estimated to be valued at USD 26.11 Bn in 2024 and is expected to reach USD 77.10 Bn by 2031, exhibiting a compound annual growth rate (CAGR) of 16.7% from 2024 to 2031.

Figure 1. Downstream Processing Market Share (%), By Region, 2024

Downstream processing refers to the purification and recovery steps in bioprocessing undertaken after fermentation to isolate the active ingredient or product of interest from cellular biomass or fermentation broth. It involves clarification to remove cellular debris and components, concentration to separate and recover the target product by reducing volume, and final purification using chromatographic techniques. Downstream processing plays a critical role in ensuring the purity, quality, and stability of biopharmaceutical products, thereby determining their success in the market. Advances in technologies for clarification and purification such as expanded bed chromatographic separation and continuous processing have enabled higher product yields and throughput at reduced costs of goods.

Market Dynamics:

The downstream processing market growth is driven by the rapid growth of the biopharmaceutical industry, preference for biologics over small molecule drugs, and strong demand for monoclonal antibodies and vaccines. However, high costs associated with downstream purification equipment and operations acts as a restraint. Advancements in continuous manufacturing and single-use technologies provide significant opportunities for market players to develop innovative solutions for integrated and modular processes. Market leaders are focusing on partnerships and M&A activities to strengthen their portfolio of purification solutions and chromatography resins.

Key features of the study:

• This report provides in-depth analysis of the global downstream processing market, and provides market size (USD Million) and compound annual growth rate (CAGR%) for the forecast period (2024-2031), considering 2023 as the base year
• It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
• This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
• It profiles key players in the global downstream processing market based on the following parameters - company highlights, products portfolio, key highlights, financial performance, and strategies
• Key companies covered as a part of this study include GE Healthcare, Merck KGaA, Thermo Fisher Scientific Inc., 3M Company, Lonza Group AG, Eppendorf AG
• Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
• The global downstream processing market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
• Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global downstream processing market

Detailed Segmentation-

• By Technique
  • Purification Techniques
  • Solid-Liquid Separation
  • Clarification/Concentration
• By Product
  • Chromatography Columns and Resins
  • Filters
  • Evaporators
  • Centrifuges
  • Other Products
• By Application
  • Antibodies Production
  • Vaccines Production
  • Insulin Production
  • Other Application
• By End User
  • Biopharmaceutical Companies
  • CMOs/CDMOs
  • Research Institutes
  • CROs
  • Others
• By Region:
  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East
  • Africa
• Company Profiles:
  • Merck KGaA
  • Thermo Fisher Scientific Inc.
  • GE Healthcare
  • Sartorius Stedim Biotech S.A.
  • Repligen Corporation
  • Pall Corporation
  • M Company
  • Eppendorf AG
  • Agilent Technologies, Inc.
  • Waters Corporation
  • Shimadzu Corporation
  • Bio-Rad Laboratories, Inc.
  • Avantor Performance Materials, LLC
  • Tosoh Corporation
  • Column Technology Inc.
  • Purolite
  • R. Grace & Co.
  • Asahi Kasei Corporation
  • Novasep Holding S.A.S
  • Boehringer Ingelheim

Table of Contents

1. Research Objectives and Assumptions

• Research Objectives
• Assumptions
• Abbreviations

2. Market Purview

• Report Description
  • Market Definition and Scope
• Executive Summary
  • Market Snapshot, By Technique
  • Market Snapshot, By Product
  • Market Snapshot, By Application
  • Market Snapshot, By End User
  • Market Snapshot, By Region
• Coherent Opportunity Map (COM)

3. Market Dynamics, Regulations, and Trends Analysis

• Market Dynamics
  • Drivers
  • Restraints
  • Opportunities
• Impact Analysis
• Market Trends
• Key Developments
• Regulatory Scenario
• Acquisitions and Partnerships Scenario
• Funding and Investments
• PEST Analysis
• Porter's Analysis

4. Global Downstream Processing Market - Impact of Coronavirus (COVID-19) Pandemic

• Overall Impact
• Government Initiatives
• COVID-19 Impact on the Market

5. Global Downstream Processing Market, By Technique, 2019 - 2031, (USD Bn)

• Overview
  • Market Share Analysis, 2024 and 2031 (%)
  • Y-o-Y Growth Analysis, 2020 - 2031
  • Segment Trends
• Purification Techniques
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Solid-Liquid Separation
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Clarification/Concentration
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)

6. Global Downstream Processing Market, By Product, 2019 - 2031, (USD Bn)

• Overview
  • Market Share Analysis, 2024 and 2031 (%)
  • Y-o-Y Growth Analysis, 2020 - 2031
  • Segment Trends
• Chromatography Columns and Resins
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Filters
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Evaporators
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Centrifuges
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Others
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)

7. Global Downstream Processing Market, By Application, 2019 - 2031, (USD Bn)

• Overview
  • Market Share Analysis, 2024 and 2031 (%)
  • Y-o-Y Growth Analysis, 2020 - 2031
  • Segment Trends
• Antibodies Production
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Vaccines Production
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Insulin Production
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Other Applications
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)

8. Global Downstream Processing Market, By Region, 2019 - 2031, (USD Bn)

• Introduction
  • Market Share Analysis, By Region, 2024 and 2031 (%)
  • Y-o-Y Growth Analysis, For Region, 2020-2031
  • Regional Trends
    • North America
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 - 2031, (USD Bn)
    • U.S.
    • Canada
• Latin America
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 - 2031, (USD Bn)
    • Brazil
    • Mexico
    • Argentina
    • Rest of Latin America
• Europe
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 - 2031, (USD Bn)
    • U.K.
    • Germany
    • Italy
    • France
    • Spain
    • Russia
    • Rest of Europe
• Asia Pacific
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 - 2031, (USD Bn)
    • China
    • India
    • Japan
    • ASEAN
    • Australia
    • South Korea
    • Rest of Asia Pacific
• Middle East
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 - 2031, (USD Bn)
    • GCC
    • Israel
    • Rest of Middle East
    • Africa
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Country/Region, 2019 - 2031, (USD Bn)
    • North Africa
    • Central Africa
    • South Africa

9. Competitive Landscape

• Company Profiles
  • Merck KGaA
    • Company Highlights
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Market Strategies
  • Thermo Fisher Scientific Inc.
  • GE Healthcare
  • Sartorius Stedim Biotech S.A.
  • Repligen Corporation
  • Pall Corporation
  • M Company
  • Eppendorf AG
  • Agilent Technologies, Inc.
  • Waters Corporation
  • Shimadzu Corporation
  • Bio-Rad Laboratories, Inc.
  • Avantor Performance Materials, LLC
  • Tosoh Corporation
  • Column Technology Inc.
  • Purolite
  • W.R. Grace & Co.
  • Asahi Kasei Corporation
  • Novasep Holding S.A.S
  • Boehringer Ingelheim

10. Analyst Recommendations

• Wheel of Fortune
• Analyst View
• Coherent Opportunity Map

11. References and Research Methodology

• References
• Research Methodology
• About us and Sales Contact