![]() |
市场调查报告书
商品编码
1886994
mRNA疗法市场规模、占有率、成长及全球产业分析:依类型、应用和地区划分的洞察,以及2024年至2032年的预测mRNA Therapeutics Market Size, Share, Growth and Global Industry Analysis By Type & Application, Regional Insights and Forecast to 2024-2032 |
||||||
全球mRNA疗法市场正经历快速发展,这得益于前所未有的科学进步、不断扩展的生物技术以及在新冠疫情期间mRNA疫苗的成功商业化。根据最新的市场研究,在强劲的研发活动和mRNA疫苗日益普及的推动下,全球mRNA疗法市场预计将在2024年达到89.1亿美元。然而,随着新冠疫苗需求的正常化和全球疫苗接种计画的调整,预计到2025年,该市场规模将萎缩至60.1亿美元。儘管目前市场暂时萎缩,但在创新、治疗应用拓展和研发管线加速的推动下,预计到2032年,mRNA市场将快速增长至214.5亿美元,2025年至2032年的复合年增长率将达到19.9%。
mRNA技术从根本上改变了製药业的格局。曾经被视为实验性平台的mRNA技术,如今已迅速发展成为传染病、癌症、罕见遗传疾病和个人化医疗领域的变革性技术。 mRNA新冠疫苗Comirnaty(辉瑞/BioNTech)和Spikebax(Moderna)的成功上市,充分展现了mRNA疗法的潜力,并在全球市场树立了良好的口碑。
北美地区在2024年以35.12%的市场占有率(价值31.3亿美元)引领全球市场,这得益于世界一流的研究基础设施、充足的公共和私人资金,以及Moderna、辉瑞、BioNTech和葛兰素史克等主要製药创新企业的强大实力。
2025年的下滑反映了新冠疫苗接种活动的缩减。然而,从2026年开始,随着各种研发管线接近商业化,预计市场将再次实现强劲的两位数成长。
推动市场成长的因素
与小分子化合物、DNA疫苗和传统生物製剂相比,mRNA疗法具有若干独特的优势。
这些优势正在加速针对流感、呼吸道合胞病毒(RSV)、痘病毒、寨卡病毒、疟疾和爱滋病等传染病的mRNA疫苗的研发。癌症疫苗和蛋白质替代疗法领域也取得了进展。
虽然疫苗目前占市场收入的主导地位,但mRNA疗法正在拓展至以下领域:
预计从2027年起,製药领域将成为成长最快的类别,首个mRNA药物预计将于2027年上市,mRNA药物市场预计将在2027年至2032年间以118.7%的复合年增长率增长,到2032年达到20亿美元。
市场限制因子
mRNA分子需要超低温才能维持稳定性。这阻碍了冷链基础设施有限的地区,特别是低收入国家,采用mRNA技术。
mRNA的生产涉及以下流程:
这些因素需要大量的资本投入,并限制了全球产能。
mRNA药物的监管框架仍在不断发展中。儘管有强而有力的科学支持,但部分人士仍持怀疑态度,尤其是在新型疫苗技术方面。
主要市场趋势
mRNA在药物研发的应用日益广泛
全球临床试验数量显着成长,截至2022年,约40%的I期临床试验是基于mRNA技术。企业将mRNA应用于以下领域:
众多合作、收购和协作表明,整个产业正在建立强大的研发管线。
递送技术的突破性创新
脂质奈米颗粒 (LNP)、聚合物和阳离子奈米颗粒正在推动以下方面的改进:
这些创新降低了毒性,并扩大了治疗应用范围。
依类型
预防(疫苗)-预计 2024 年市占率最大
预计 2024 年,疫苗细分市场将占最大的市场占有率,这主要得益于 COVID-19 疫苗和呼吸道合胞病毒 (RSV) 疫苗的批准。
已核准的产品包括:
正在研发的非新冠疫苗包括:
药物/药物 - 成长最快的领域
随着 mRNA 疗法的商业化,预计从 2027 年起将快速成长,尤其是在肿瘤领域。
依应用领域
传染病领域 - 截至目前处于领先地位2024年
该领域占领先地位,因为截至2025年初,所有核准的mRNA产品均针对传染病。
肿瘤领域-高成长领域
多种癌症疫苗正在研发中,包括BioNTech公司用于治疗非小细胞肺癌(NSCLC)的BNT116。
依分销管道
北美 - 市场领导者(2024 年市场规模:31.3 亿美元)
主要驱动因素
欧洲
德国和法国引领该地区,是 BioNTech、CureVac 和赛诺菲等主要公司的所在地。
亚太地区
这是成长最快的地区,主要受以下因素驱动:
其他
随着拉丁美洲、中东和非洲医疗基础设施的发展,这些地区对疫苗的兴趣日益浓厚。
The global mRNA therapeutics market is undergoing a period of rapid evolution, driven by unprecedented scientific advancements, expanding biotechnology capabilities, and successful commercialization of mRNA-based vaccines during the COVID-19 pandemic. According to the latest market intelligence, the global mRNA therapeutics market size reached USD 8.91 billion in 2024, supported by robust R&D activities and rising acceptance of mRNA vaccines. However, the market is projected to decrease to USD 6.01 billion in 2025 due to normalization in COVID-19 vaccine demand and shifts in immunization programs worldwide. Despite this temporary contraction, the market is expected to surge to USD 21.45 billion by 2032, driven by innovation, expanding therapeutic applications, and accelerating pipeline development, achieving a CAGR of 19.9% between 2025 and 2032.
The mRNA field has fundamentally reshaped the pharmaceutical landscape. What was once considered an experimental platform has rapidly emerged as a transformational technology capable of addressing infectious diseases, cancer, rare genetic disorders, and personalized medicine. The successful deployment of mRNA COVID-19 vaccines-Comirnaty (Pfizer/BioNTech) and Spikevax (Moderna)-validated the potential of mRNA-based therapeutics and established strong global market confidence.
North America dominated the global market with a 35.12% share in 2024, valued at USD 3.13 billion, owing to its world-leading research infrastructure, substantial public and private funding, and strong presence of major pharmaceutical innovators such as Moderna, Pfizer, BioNTech, and GSK.
The decline in 2025 reflects reduced COVID-19 vaccination campaigns. However, post-2026, the market is anticipated to return to strong double-digit expansion as diverse pipelines move closer to commercialization.
Drivers Shaping Market Growth
mRNA therapies offer several unique advantages over small molecules, DNA vaccines, and conventional biologics:
These benefits are accelerating the development of mRNA vaccines for infectious diseases like influenza, RSV, Mpox, Zika, malaria, and HIV, as well as therapeutic vaccines for cancer and protein-replacement therapies.
Though vaccines dominate current market revenues, mRNA therapies are expanding into:
The drugs/medications segment is expected to become the fastest-growing category post-2027, supported by the anticipated launch of the first mRNA drug in 2027 and projections that the mRNA drug market will reach USD 2 billion by 2032 at a CAGR of 118.7% from 2027 to 2032.
Market Restraints
mRNA molecules require ultra-cold temperatures for stability. This continues to hinder adoption in regions with limited cold-chain infrastructure, particularly low-income countries.
mRNA production involves:
These factors contribute to high capital expenditures and limited global production capacity.
The regulatory framework for mRNA drugs is still evolving. Despite strong scientific backing, skepticism persists among certain segments of the population, particularly regarding new vaccine technologies.
Key Market Trends
Growing Adoption of mRNA in Drug Development
There has been substantial growth in clinical trials globally, with approximately 40% of mRNA-based clinical trials in Phase I as of 2022. Companies are using mRNA for:
Multiple partnerships, acquisitions, and collaborations indicate a strong pipeline across the industry.
Breakthrough Innovations in Delivery Technologies
LNPs, polymers, and cationic nanoparticles are improving:
These innovations reduce toxicity and allow broader therapeutic applications.
By Type
Prophylactic (Vaccines) - Dominant in 2024
The vaccines segment accounted for the highest share in 2024 due to COVID-19 and RSV vaccine approvals.
Approved products include:
Non-COVID vaccines in the pipeline include:
Drugs/Medications - Fastest Growing Segment
Expected boom after 2027 as mRNA therapeutics enter commercialization, especially in oncology.
By Application
Infectious Diseases - Leading in 2024
Because all approved mRNA products as of early 2025 target infectious diseases, this segment dominates.
Oncology - High Future Growth
Multiple cancer vaccines are in development, including BioNTech's BNT116 for NSCLC.
By Distribution Channel
North America - Market Leader (2024 Value: USD 3.13 Billion)
Key drivers:
Europe
Germany and France lead the region with major companies such as BioNTech, CureVac, and Sanofi.
Asia Pacific
Fastest-growing region, driven by:
Rest of the World
Latin America and Middle East & Africa show rising interest as healthcare infrastructure improves.
Competitive Landscape
Major players include:
These companies are investing heavily in:
Conclusion
The global mRNA therapeutics market is transforming rapidly, driven by technological innovation, expanded pipeline applications, rising funding, and growing acceptance of mRNA-based medicines. While the market dips from USD 8.91 billion in 2024 to USD 6.01 billion in 2025, it is set to rebound strongly, reaching USD 21.45 billion by 2032. With breakthroughs expected across oncology, infectious diseases, and rare genetic disorders, mRNA technology is positioned to become one of the most influential healthcare innovations of the 21st century.
Segmentation
By Type
By Application
By Distribution Channel
By Region