Product Code: GVR-4-68039-293-5
Anticoagulant Reversal Drugs Market Growth & Trends:
The global anticoagulant reversal drugs market size is expected to reach USD 2.78 billion by 2030, according to a new report by Grand View Research, Inc. It is expected to expand at a CAGR of 12.3% from 2025 to 2030. The rising number of bleeding disorders, the introduction of new drugs, and the growing number of cases requiring anticoagulant therapies are some of the factors anticipated to foster market growth during the forecast period.
In October 2015, Praxbind (idarucizumab) by Boehringer Ingelheim Pharmaceuticals was approved as an anticoagulant reversal drug indicated for patients treated with Pradaxa (dabigatran) during emergency surgery or uncontrolled or life-threatening bleeding. Hence, the availability of these anticoagulation reversal drugs allows doctors and patients to consider such treatment options with greater confidence, therefore boosting the demand for anticoagulant reversal drugs.
Bleeding disorders like hemophilia can be acquired or inherited. However, other bleeding disorders can occur from conditions, such as HIV, anemia, leukemia, cirrhosis of the liver, and vitamin K deficiency. According to the National Heart, Lung, and Blood Institute, more than 3 million people in the U.S. are affected with anemia, which is the most common blood disorder. The Leukemia & Lymphoma Society (LLS) stated that in the year 2020, the number of people expected to be diagnosed with leukemia is around 60,530. A rise in bleeding disorders is increasing the demand for anticoagulants, thus fueling the market growth.
However, the high cost of these reversal therapies is anticipated to restrain the market growth. As per the American College of Cardiology, 4-F PCC (Kcentra) helps in treating bleeding cases caused by rivaroxaban and apixaban and it is dosed at 50 units/kg. Its average wholesale price is USD 2.90 per unit, therefore treating a patient whose weight is 100 kg would cost around USD 14,500.
Anticoagulant Reversal Drugs Market Report Highlights:
- The idarucizumab segment dominated the market, with a revenue share of 36.8% in 2024, driven by its high specificity for dabigatran as an effective option for reversing anticoagulation in emergencies.
- Hospital pharmacies dominated the market with the largest revenue share of 48.6% in 2024, driven by the need for immediate access to anticoagulant reversal agents in emergencies.
- North America anticoagulant reversal drugs market dominated the global market with a revenue share of 38.6% in 2024.
Table of Contents
Chapter 1. Methodology and Scope
- 1.1. Market Segmentation & Scope
- 1.2. Segment Definitions
- 1.2.1. Product Type
- 1.2.2. Distribution Channel
- 1.3. Estimates and Forecast Timeline
- 1.4. Research Methodology
- 1.5. Information Procurement
- 1.5.1. Purchased Database
- 1.5.2. GVR's Internal Database
- 1.5.3. Secondary Sources
- 1.5.4. Primary Research
- 1.6. Information Analysis
- 1.6.1. Data Analysis Models
- 1.7. Market Formulation & Data Visualization
- 1.8. Model Details
- 1.8.1. Commodity Flow Analysis
- 1.9. List of Secondary Sources
- 1.10. Objectives
Chapter 2. Executive Summary
- 2.1. Market Snapshot
- 2.2. Segment Snapshot
- 2.3. Competitive Landscape Snapshot
Chapter 3. Anticoagulant Reversal Drugs Market Variables, Trends, & Scope
- 3.1. Market Lineage Outlook
- 3.2. Market Dynamics
- 3.2.1. Market Driver Analysis
- 3.2.2. Market Restraint Analysis
- 3.3. Business Environment Analysis
- 3.3.1. Industry Analysis - Porter's Five Forces Analysis
- 3.3.1.1. Supplier Power
- 3.3.1.2. Buyer Power
- 3.3.1.3. Substitution Threat
- 3.3.1.4. Threat of New Entrants
- 3.3.1.5. Competitive Rivalry
- 3.3.2. PESTLE Analysis
Chapter 4. Anticoagulant Reversal Drugs Market: Product Type Business Analysis
- 4.1. Product Type Market Share, 2024 & 2030
- 4.2. Product Type Segment Dashboard
- 4.3. Market Size & Forecasts and Trend Analysis, by Product Type, 2018 to 2030 (USD Million)
- 4.4. Prothrombin Complex Concentrates
- 4.4.1. Prothrombin Complex Concentrates Market, 2018 - 2030 (USD Million)
- 4.5. Phytonadione (Vitamin K)
- 4.5.1. Phytonadione (Vitamin K) Market, 2018 - 2030 (USD Million)
- 4.6. Andexanet Alfa
- 4.6.1. Andexanet Alfa Market, 2018 - 2030 (USD Million)
- 4.7. Idarucizumab
- 4.7.1. Idarucizumab Market, 2018 - 2030 (USD Million)
- 4.8. Protamine
- 4.8.1. Protamine Market, 2018 - 2030 (USD Million)
- 4.9. Others
- 4.9.1. Others Market, 2018 - 2030 (USD Million)
Chapter 5. Anticoagulant Reversal Drugs Market: Distribution Channel Business Analysis
- 5.1. Distribution Channel Market Share, 2024 & 2030
- 5.2. Distribution Channel Segment Dashboard
- 5.3. Market Size & Forecasts and Trend Analysis, by Distribution Channel, 2018 to 2030 (USD Million)
- 5.4. Hospital Pharmacy
- 5.4.1. Hospital Pharmacy Market, 2018 - 2030 (USD Million)
- 5.5. Retail Pharmacy
- 5.5.1. Retail Pharmacy Market, 2018 - 2030 (USD Million)
- 5.6. Online Pharmacy
- 5.6.1. Online Pharmacy Market, 2018 - 2030 (USD Million)
Chapter 6. Anticoagulant Reversal Drugs Market: Regional Estimates & Trend Analysis by Product Type
- 6.1. Regional Market Share Analysis, 2024 & 2030
- 6.2. Regional Market Dashboard
- 6.3. Market Size, & Forecasts Trend Analysis, 2018 to 2030:
- 6.4. North America
- 6.4.1. North America Anticoagulant Reversal Drugs Market Estimates and Forecasts, by Country, 2018 - 2030 (USD Million)
- 6.4.2. U.S.
- 6.4.2.1. Key Country Dynamics
- 6.4.2.2. Regulatory Framework
- 6.4.2.3. Competitive Insights
- 6.4.2.4. U.S. Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.4.3. Canada
- 6.4.3.1. Key Country Dynamics
- 6.4.3.2. Regulatory Framework
- 6.4.3.3. Competitive Insights
- 6.4.3.4. Canada Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.4.4. Mexico
- 6.4.4.1. Key Country Dynamics
- 6.4.4.2. Regulatory Framework
- 6.4.4.3. Competitive Insights
- 6.4.4.4. Mexico Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.5. Europe
- 6.5.1. Europe Anticoagulant Reversal Drugs Market Estimates and Forecasts, by Country, 2018 - 2030 (USD Million)
- 6.5.2. UK
- 6.5.2.1. Key Country Dynamics
- 6.5.2.2. Regulatory Framework
- 6.5.2.3. Competitive Insights
- 6.5.2.4. UK Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.5.3. Germany
- 6.5.3.1. Key Country Dynamics
- 6.5.3.2. Regulatory Framework
- 6.5.3.3. Competitive Insights
- 6.5.3.4. Germany Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.5.4. France
- 6.5.4.1. Key Country Dynamics
- 6.5.4.2. Regulatory Framework
- 6.5.4.3. Competitive Insights
- 6.5.4.4. France Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.5.5. Italy
- 6.5.5.1. Key Country Dynamics
- 6.5.5.2. Regulatory Framework
- 6.5.5.3. Competitive Insights
- 6.5.5.4. Italy Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.5.6. Spain
- 6.5.6.1. Key Country Dynamics
- 6.5.6.2. Regulatory Framework
- 6.5.6.3. Competitive Insights
- 6.5.6.4. Spain Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.5.7. Norway
- 6.5.7.1. Key Country Dynamics
- 6.5.7.2. Regulatory Framework
- 6.5.7.3. Competitive Insights
- 6.5.7.4. Norway Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.5.8. Denmark
- 6.5.8.1. Key Country Dynamics
- 6.5.8.2. Regulatory Framework
- 6.5.8.3. Competitive Insights
- 6.5.8.4. Denmark Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.5.9. Sweden
- 6.5.9.1. Key Country Dynamics
- 6.5.9.2. Regulatory Framework
- 6.5.9.3. Competitive Insights
- 6.5.9.4. Sweden Anticoagulant Reversal Drugs Market Estimates and Forecasts, by Country, 2018 - 2030 (USD Million)
- 6.6. Asia Pacific
- 6.6.1. Asia Pacific Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.6.2. Japan
- 6.6.2.1. Key Country Dynamics
- 6.6.2.2. Regulatory Framework
- 6.6.2.3. Competitive Insights
- 6.6.2.4. Japan Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.6.3. China
- 6.6.3.1. Key Country Dynamics
- 6.6.3.2. Regulatory Framework
- 6.6.3.3. Competitive Insights
- 6.6.3.4. China Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.6.4. India
- 6.6.4.1. Key Country Dynamics
- 6.6.4.2. Regulatory Framework
- 6.6.4.3. Competitive Insights
- 6.6.4.4. India Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.6.5. South Korea
- 6.6.5.1. Key Country Dynamics
- 6.6.5.2. Regulatory Framework
- 6.6.5.3. Competitive Insights
- 6.6.5.4. South Korea Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.6.6. Australia
- 6.6.6.1. Key Country Dynamics
- 6.6.6.2. Regulatory Framework
- 6.6.6.3. Competitive Insights
- 6.6.6.4. Australia Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.6.7. Thailand
- 6.6.7.1. Key Country Dynamics
- 6.6.7.2. Regulatory Framework
- 6.6.7.3. Competitive Insights
- 6.6.7.4. Thailand Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.7. Latin America
- 6.7.1. Latin America Anticoagulant Reversal Drugs Market Estimates and Forecasts, by Country, 2018 - 2030 (USD Million)
- 6.7.2. Brazil
- 6.7.2.1. Key Country Dynamics
- 6.7.2.2. Regulatory Framework
- 6.7.2.3. Competitive Insights
- 6.7.2.4. Brazil Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.7.3. Argentina
- 6.7.3.1. Key Country Dynamics
- 6.7.3.2. Regulatory Framework
- 6.7.3.3. Competitive Insights
- 6.7.3.4. Argentina Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.8. MEA
- 6.8.1. MEA Anticoagulant Reversal Drugs Market Estimates and Forecasts, by Country, 2018 - 2030 (USD Million)
- 6.8.2. South Africa
- 6.8.2.1. Key Country Dynamics
- 6.8.2.2. Regulatory Framework
- 6.8.2.3. Competitive Insights
- 6.8.2.4. South Africa Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.8.3. Saudi Arabia
- 6.8.3.1. Key Country Dynamics
- 6.8.3.2. Regulatory Framework
- 6.8.3.3. Competitive Insights
- 6.8.3.4. Saudi Arabia Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.8.4. UAE
- 6.8.4.1. Key Country Dynamics
- 6.8.4.2. Regulatory Framework
- 6.8.4.3. Competitive Insights
- 6.8.4.4. UAE Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 6.8.5. Kuwait
- 6.8.5.1. Key Country Dynamics
- 6.8.5.2. Regulatory Framework
- 6.8.5.3. Competitive Insights
- 6.8.5.4. Kuwait Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
Chapter 7. Anticoagulant Reversal Drugs Market: Regional Estimates & Trend Analysis by Distribution Channel
- 7.1. Regional Market Share Analysis, 2024 & 2030
- 7.2. Regional Market Dashboard
- 7.3. Market Size, & Forecasts Trend Analysis, 2018 to 2030:
- 7.4. North America
- 7.4.1. North America Anticoagulant Reversal Drugs Market Estimates and Forecasts, by Country, 2018 - 2030 (USD Million)
- 7.4.2. U.S.
- 7.4.2.1. Key Country Dynamics
- 7.4.2.2. Regulatory Framework
- 7.4.2.3. Competitive Insights
- 7.4.2.4. U.S. Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.4.3. Canada
- 7.4.3.1. Key Country Dynamics
- 7.4.3.2. Regulatory Framework
- 7.4.3.3. Competitive Insights
- 7.4.3.4. Canada Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.4.4. Mexico
- 7.4.4.1. Key Country Dynamics
- 7.4.4.2. Regulatory Framework
- 7.4.4.3. Competitive Insights
- 7.4.4.4. Mexico Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5. Europe
- 7.5.1. Europe Anticoagulant Reversal Drugs Market Estimates and Forecasts, by Country, 2018 - 2030 (USD Million)
- 7.5.2. UK
- 7.5.2.1. Key Country Dynamics
- 7.5.2.2. Regulatory Framework
- 7.5.2.3. Competitive Insights
- 7.5.2.4. UK Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.3. Germany
- 7.5.3.1. Key Country Dynamics
- 7.5.3.2. Regulatory Framework
- 7.5.3.3. Competitive Insights
- 7.5.3.4. Germany Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.4. France
- 7.5.4.1. Key Country Dynamics
- 7.5.4.2. Regulatory Framework
- 7.5.4.3. Competitive Insights
- 7.5.4.4. France Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.5. Italy
- 7.5.5.1. Key Country Dynamics
- 7.5.5.2. Regulatory Framework
- 7.5.5.3. Competitive Insights
- 7.5.5.4. Italy Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.6. Spain
- 7.5.6.1. Key Country Dynamics
- 7.5.6.2. Regulatory Framework
- 7.5.6.3. Competitive Insights
- 7.5.6.4. Spain Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.7. Norway
- 7.5.7.1. Key Country Dynamics
- 7.5.7.2. Regulatory Framework
- 7.5.7.3. Competitive Insights
- 7.5.7.4. Norway Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.8. Denmark
- 7.5.8.1. Key Country Dynamics
- 7.5.8.2. Regulatory Framework
- 7.5.8.3. Competitive Insights
- 7.5.8.4. Denmark Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.5.9. Sweden
- 7.5.9.1. Key Country Dynamics
- 7.5.9.2. Regulatory Framework
- 7.5.9.3. Competitive Insights
- 7.5.9.4. Sweden Anticoagulant Reversal Drugs Market Estimates and Forecasts, by Country, 2018 - 2030 (USD Million)
- 7.6. Asia Pacific
- 7.6.1. Asia Pacific Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.6.2. Japan
- 7.6.2.1. Key Country Dynamics
- 7.6.2.2. Regulatory Framework
- 7.6.2.3. Competitive Insights
- 7.6.2.4. Japan Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.6.3. China
- 7.6.3.1. Key Country Dynamics
- 7.6.3.2. Regulatory Framework
- 7.6.3.3. Competitive Insights
- 7.6.3.4. China Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.6.4. India
- 7.6.4.1. Key Country Dynamics
- 7.6.4.2. Regulatory Framework
- 7.6.4.3. Competitive Insights
- 7.6.4.4. India Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.6.5. South Korea
- 7.6.5.1. Key Country Dynamics
- 7.6.5.2. Regulatory Framework
- 7.6.5.3. Competitive Insights
- 7.6.5.4. South Korea Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.6.6. Australia
- 7.6.6.1. Key Country Dynamics
- 7.6.6.2. Regulatory Framework
- 7.6.6.3. Competitive Insights
- 7.6.6.4. Australia Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.6.7. Thailand
- 7.6.7.1. Key Country Dynamics
- 7.6.7.2. Regulatory Framework
- 7.6.7.3. Competitive Insights
- 7.6.7.4. Thailand Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.7. Latin America
- 7.7.1. Latin America Anticoagulant Reversal Drugs Market Estimates and Forecasts, by Country, 2018 - 2030 (USD Million)
- 7.7.2. Brazil
- 7.7.2.1. Key Country Dynamics
- 7.7.2.2. Regulatory Framework
- 7.7.2.3. Competitive Insights
- 7.7.2.4. Brazil Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.7.3. Argentina
- 7.7.3.1. Key Country Dynamics
- 7.7.3.2. Regulatory Framework
- 7.7.3.3. Competitive Insights
- 7.7.3.4. Argentina Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.8. MEA
- 7.8.1. MEA Anticoagulant Reversal Drugs Market Estimates and Forecasts, by Country, 2018 - 2030 (USD Million)
- 7.8.2. South Africa
- 7.8.2.1. Key Country Dynamics
- 7.8.2.2. Regulatory Framework
- 7.8.2.3. Competitive Insights
- 7.8.2.4. South Africa Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.8.3. Saudi Arabia
- 7.8.3.1. Key Country Dynamics
- 7.8.3.2. Regulatory Framework
- 7.8.3.3. Competitive Insights
- 7.8.3.4. Saudi Arabia Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.8.4. UAE
- 7.8.4.1. Key Country Dynamics
- 7.8.4.2. Regulatory Framework
- 7.8.4.3. Competitive Insights
- 7.8.4.4. UAE Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
- 7.8.5. Kuwait
- 7.8.5.1. Key Country Dynamics
- 7.8.5.2. Regulatory Framework
- 7.8.5.3. Competitive Insights
- 7.8.5.4. Kuwait Anticoagulant Reversal Drugs Market Estimates and Forecasts, 2018 - 2030 (USD Million)
Chapter 8. Competitive Landscape
- 8.1. Participant Overview
- 8.2. Company Market Position Analysis
- 8.3. Company Categorization
- 8.4. Strategy Mapping
- 8.5. Company Profiles/Listing
- 8.5.1. Pfizer Inc
- 8.5.1.1. Overview
- 8.5.1.2. Financial Performance
- 8.5.1.3. Product Benchmarking
- 8.5.1.4. Strategic Initiatives
- 8.5.2. AstraZeneca
- 8.5.2.1. Overview
- 8.5.2.2. Financial Performance
- 8.5.2.3. Product Benchmarking
- 8.5.2.4. Strategic Initiatives
- 8.5.3. Dr. Reddy's Laboratories Ltd
- 8.5.3.1. Overview
- 8.5.3.2. Financial Performance
- 8.5.3.3. Product Benchmarking
- 8.5.3.4. Strategic Initiatives
- 8.5.4. Endo International plc
- 8.5.4.1. Overview
- 8.5.4.2. Financial Performance
- 8.5.4.3. Product Benchmarking
- 8.5.4.4. Strategic Initiatives
- 8.5.5. Teva Pharmaceutical Industries Ltd
- 8.5.5.1. Overview
- 8.5.5.2. Financial Performance
- 8.5.5.3. Product Benchmarking
- 8.5.5.4. Strategic Initiatives
- 8.5.6. Sun Pharmaceutical Industries Ltd
- 8.5.6.1. Overview
- 8.5.6.2. Financial Performance
- 8.5.6.3. Product Benchmarking
- 8.5.6.4. Strategic Initiatives
- 8.5.7. Mylan N.V.
- 8.5.7.1. Overview
- 8.5.7.2. Financial Performance
- 8.5.7.3. Product Benchmarking
- 8.5.7.4. Strategic Initiatives
- 8.5.8. Novartis AG.
- 8.5.8.1. Overview
- 8.5.8.2. Financial Performance
- 8.5.8.3. Product Benchmarking
- 8.5.8.4. Strategic Initiatives
- 8.5.9. Lupin
- 8.5.9.1. Overview
- 8.5.9.2. Financial Performance
- 8.5.9.3. Product Benchmarking
- 8.5.9.4. Strategic Initiatives
- 8.5.10. Cipla Inc
- 8.5.10.1. Overview
- 8.5.10.2. Financial Performance
- 8.5.10.3. Product Benchmarking
- 8.5.10.4. Strategic Initiatives