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市场调查报告书
商品编码
1519769
2024-2032 年囊性纤维化治疗市场报告(依药物类别、药物分子类型、给药途径、最终使用者和地区)Cystic Fibrosis Therapeutics Market Report by Drug Class, Drug Molecule Type, Route of Administration, End-User, and Region 2024-2032 |
IMARC Group年,全球囊性纤维化治疗市场规模达到 72 亿美元。囊性纤维化盛行率不断上升,个人对基于遗传因素的个人化治疗方法的偏好不断增加,以及基因疗法最新进展的广泛利用是推动市场成长的一些主要因素。
囊性纤维化治疗可以控制影响呼吸和消化系统的遗传性疾病的症状。它涵盖一系列药物,包括 CFTR 调节剂和基因疗法,提供量身定制的治疗方案。它透过增强 CFTR 蛋白的功能来帮助纠正导致 CF 的潜在遗传缺陷。它透过控制症状和减缓疾病进展来提高生活品质。它可以增强肺功能,帮助 CF 患者更轻鬆地呼吸并减轻呼吸道症状。
个人对基于遗传因素的个人化治疗方法的日益偏好正在加强市场的成长。除此之外,各国政府纷纷推出针对CF研究和治疗开发的政策和资金,这为CF的研究和治疗开发提供了良好的市场前景。此外,对孤儿药开发的监管激励措施不断加强,正在鼓励製药公司投资 CF 疗法。此外,製药公司、研究机构和医疗保健提供者之间不断加强的合作正在加速新疗法的开发。此外,穿戴式装置和远距医疗等技术的广泛使用正在增强患者监测和治疗服务。
CFTR 调变器的进步
CFTR调节药物的开发和持续改进是促进市场成长的主要因素之一。这些药物直接针对有缺陷的 CFTR 蛋白,这是 CF 患者产生浓稠黏液和随后出现健康併发症的原因。除此之外,製药公司不断投资于研发 (R&D) 活动,以推出新一代 CFTR 调节剂,以提供更高的有效性和更广泛的适用性。这些进步提供了更全面的解决方案并改善了个人的整体福祉。它们还支持改善特定 CF 患者群体的黏液清除、减少呼吸道症状和增强肺功能。
基因疗法的发展
基因疗法的发展是促进市场成长的另一个主要因素。这些创新疗法透过将有缺陷的 CFTR 基因的功能性拷贝引入受影响的细胞中,帮助解决 CF 的根本原因,并促进 CF 的治癒或长期管理。此外,基因疗法最新进展的使用不断增加,例如 Kaftrio 和 Trikafta 等基于基因的治疗方法已被批准用于治疗 CF 症状,这提供了良好的市场前景。除此之外,基因疗法的发展正在加强市场的成长。这些疗法有助于提供更有效和更有针对性的治疗,扩大治疗选择,并促进对潜在治疗方法的研究。
增加盛行率和早期诊断
由于多种因素,CF 盛行率不断上升,特别是在千禧世代人群中,正在推动对治疗药物的需求。同时,诊断能力的提高正在创造积极的市场前景。此外,医疗保健系统越来越擅长透过新生儿筛检计划和基因检测来识别 CF 病例。除此之外,早期诊断可以在更年轻的时候开始治疗,这可以显着影响疾病进展并改善长期结果。此外,基因检测和新生儿筛检计画的持续进步使得婴幼儿 CF 的诊断变得更快、更可靠。
The global cystic fibrosis therapeutics market size reached US$ 7.2 Billion in 2023. Looking forward, IMARC Group expects the market to reach US$ 14.7 Billion by 2032, exhibiting a growth rate (CAGR) of 7.9% during 2024-2032. The rising prevalence of cystic fibrosis, increasing preferences of individuals for personalized treatment approaches based on genetic factors, and the widespread utilization of recent advancements in gene therapy are some of the major factors propelling the market growth.
Cystic fibrosis therapeutics enables management of the symptoms of a genetic disease affecting the respiratory and digestive systems. It encompasses a range of drugs, including CFTR modulators and gene therapy, offering tailored treatment options. It helps correct the underlying genetic defect responsible for CF by enhancing the function of the CFTR protein. It contributes to a better quality of life by managing symptoms and slowing disease progression. It can enhance lung function, helping individuals with CF breathe more easily and reducing respiratory symptoms.
Rising preferences of individuals for personalized treatment approaches based on genetic factors is strengthening the growth of the market. Apart from this, governing authorities of various countries are introducing policies and funding for CF research and treatment development, which is offering a favorable market outlook. Additionally, a continuous rise in regulatory incentives for orphan drug development is encouraging pharmaceutical companies to invest in CF therapeutics. Moreover, the rising collaborative efforts between pharmaceutical companies, research institutions, and healthcare providers are accelerating the development of new therapies. Furthermore, the widespread use of technology, such as wearable devices and telemedicine, is enhancing patient monitoring and treatment delivery.
Advancements in CFTR modulators
The development and continued improvement of CFTR modulator drugs represent one of the primary factors contributing to the market growth. These medications directly target the defective CFTR protein, which is responsible for the thick mucus production and subsequent health complications in individuals with CF. Apart from this, pharmaceutical companies are continuously investing in research and development (R&D) activities to introduce new generations of CFTR modulators that offer greater effectiveness and broader applicability. These advancements provide more comprehensive solutions and improve the overall well-being of individuals. They also support improved mucus clearance, reduced respiratory symptoms, and enhanced lung function in specific CF patient populations.
Development of gene-based therapies
The development of gene-based therapies is another major factor facilitating the market growth. These innovative treatments help address the root cause of CF by introducing functional copies of the defective CFTR gene into affected cells and facilitating a cure or long-term management of CF. Additionally, the rising utilization of recent advancements in gene therapy, such as the approval of gene-based treatments like Kaftrio and Trikafta for treating CF symptoms is offering a favorable market outlook. Apart from this, the evolution of gene-based therapies is strengthening the growth of the market. These therapies aid in providing more effective and targeted treatments, expanding treatment options, and fostering research into potential curative approaches.
Increasing prevalence and early diagnosis
The rising prevalence of CF, especially among the millennial population due to several factors, is driving the demand for therapeutics. Along with this, improved diagnostic capabilities are creating a positive market outlook. Additionally, healthcare systems are becoming more adept at identifying CF cases through newborn screening programs and genetic testing. Apart from this, early diagnosis allows for the initiation of treatment at a younger age, which can significantly impact disease progression and improve long-term outcomes. Furthermore, ongoing advancements in genetic testing and newborn screening programs are allowing for quicker and more reliable diagnosis of CF in infants and young children.
IMARC Group provides an analysis of the key trends in each segment of the market report, along with forecasts at the global, regional, and country levels from 2024-2032. Our report has categorized the market based on drug class, drug molecule type, route of administration, and end-user.
Pancreatic Enzyme Supplements
Mucolytics
Bronchodilators
CFTR Modulators
Antibiotics
Others
CFTR modulators hold the largest market share
A detailed breakup and analysis of the market based on the drug class has also been provided in the report. This includes pancreatic enzyme supplements, mucolytics, bronchodilators, CFTR modulators, antibiotics, and others. According to the report, CFTR modulators accounted for the largest market share as they offer a highly targeted treatment approach. They address the root cause of CF at the molecular level, focusing on the defective CFTR protein. They work by improving the function of the defective CFTR protein and regulate the flow of salt and fluids in and out of cells. Additionally, the expanded approval for use in various CF patient populations, including those with specific genetic mutations drives its demand across the globe. Apart from this, pharmaceutical companies continue to invest heavily in research activities to create new generations of CFTR modulators. These efforts aim to improve the effectiveness of existing drugs and develop new ones, ensuring a competitive edge in the market.
Small Molecule Drugs
Biologics
Small molecule drugs account for the majority of the market share
The report has provided a detailed breakup and analysis of the market based on the drug molecule type. This includes small molecule drugs and biologics. According to the report, small molecule drugs represented the largest segment as they have excellent bioavailability and get efficiently absorbed into the bloodstream after oral administration. This ensures that a significant portion of the drug reaches its target site, enhancing therapeutic efficacy. Apart from this, they are generally cost-effective to manufacture, making them attractive to pharmaceutical companies. The production processes for these drugs are well-established, allowing for economies of scale and efficient mass production. Moreover, regulatory agencies, such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), have established clear guidelines for the development and approval of small molecule drugs. This regulatory support ensures their safety, quality, and efficacy, bolstering confidence among healthcare professionals and patients.
Oral Drugs
Inhaled Drugs
Oral drugs dominate the market
A detailed breakup and analysis of the market based on the route of administration has also been provided in the report. This includes oral drugs and inhaled drugs. According to the report, oral drugs accounted for the largest market share as they are often more cost-effective than other forms of medication delivery. They require less infrastructure for administration and reduce the need for healthcare professionals' involvement, leading to lower overall healthcare costs. Additionally, they do not involve needles or invasive procedures, making them more tolerable for a broader patient population. Apart from this, they are usually administered in the form of tablets or capsules, offering a level of accessibility and convenience. Apart from this, patients can take these medications easily without the need for specialized medical personnel or equipment. This convenience supports long-term treatments, chronic conditions, and self-administered therapies for several chronic diseases.
Hospitals
Clinics
Others
Hospitals dominate the market
The report has provided a detailed breakup and analysis of the market based on the end-user. This includes hospitals, clinics, and others. According to the report, hospitals represented the largest segment as they provide comprehensive healthcare services under one roof. They offer a wide range of medical specialties, including emergency care, surgery, radiology, pathology, and specialized clinics. Apart from this, they are primarily associated with acute care, which involves the treatment of severe and life-threatening conditions. Moreover, they are equipped with state-of-the-art medical equipment and technology. This includes advanced diagnostic tools, imaging systems, surgical robots, and intensive care units. These resources enable hospitals to deliver cutting-edge medical treatments and procedures. Furthermore, many hospitals are affiliated with medical schools and research institutions, fostering an environment of continuous learning and innovation. This research-driven approach leads to the development of new medical treatments, therapies, and best practices.
North America
United States
Canada
Asia Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
Europe leads the market, accounting for the largest cystic fibrosis therapeutics market share
The market research report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, Europe accounted for the largest market share since the region has a well-developed healthcare infrastructure with widespread access to medical facilities and specialized CF centers. Additionally, Europe has a relatively high prevalence of CF. This increased prevalence drives research and development (R&D) efforts as well as market demand for CF therapeutics. Apart from this, Europe is home to some of the largest pharmaceutical companies in the world. These companies invest heavily in CF therapeutics, leading to the development of innovative treatments. Furthermore, the European Medicines Agency (EMA) provides a clear regulatory pathway for the approval of CF drugs. Moreover, many European governments allocate substantial funding to support CF research and treatment. This funding accelerates the development of new therapies and promotes market growth.
Companies are investing heavily in research and development (R&D) activities to discover new treatments and medications that target the underlying causes of cystic fibrosis. Additionally, they are working on therapies tailored to specific genetic mutations associated with cystic fibrosis. This ensures a more effective and targeted approach to treatment. Apart from this, many companies are forming partnerships with academic institutions, research organizations, and other pharma companies to accelerate drug development and bring new therapies to market more quickly. Furthermore, they are continuously conducting and investing in phase I, II, and III clinical trials to test the efficacy and safety of new cystic fibrosis therapies.
AbbVie Inc.
Alaxia
Alcresta Therapeutics Inc.
Allergan
AstraZeneca
F. Hoffmann-La Roche Ltd.
Gilead Sciences Inc.
Merck & Co. Inc.
Novartis AG
Teva Pharmaceutical Industries Ltd.
Vertex Pharmaceuticals Inc.
(Please note that this is only a partial list of the key players, and the complete list is provided in the report.)
In December 2022, Vertex Pharmaceuticals Inc. announced that the U.S. Food and Drug Administration cleared its Investigational New Drug (IND) application for VX-522, a messenger ribonucleic acid (mRNA) therapy targeted at treating the underlying cause of cystic fibrosis (CF) lung disease.
In October 2020, AbbVie Inc. announced the partnership with Roche and the acquisition of the TMEM16A potentiators portfolio. The relationship influenced the expansion of the company's product line.