市场调查报告书
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1609693
2025-2033 年日本寡核苷酸合成市场报告(按产品、应用(PCR 引子、PCR 测定和麵板、定序、DNA 微阵列、萤光原位杂交、反义寡核苷酸等)、最终用途和区域)Japan Oligonucleotide Synthesis Market Report by Product, Application (PCR Primers, PCR Assays and Panels, Sequencing, DNA Microarrays, Fluorescence In-Situ Hybridization, Antisense Oligonucleotides, and Others), End Use, and Region 2025-2033 |
2024年日本寡核苷酸合成市场规模达2.049IMARC Group美元。新型治疗策略的广泛采用,加上生物资讯学和资料科学的显着成长,主要推动了市场的成长。
寡核苷酸合成是建构具有特定序列的短 DNA 或 RNA 分子(称为寡核苷酸)的过程。这些序列的长度可以从几个碱基到大约 200 个核苷酸不等。该过程通常在受控实验室环境中透过化学合成进行,通常利用固相亚磷酰胺化学。在这种方法中,核苷酸被顺序添加到不断增长的链中,每次添加都涉及一系列化学反应。这项技术使科学家能够为一系列应用创建客製化的寡核苷酸,包括基因合成、聚合酶炼式反应 (PCR)、CRISPR-Cas9 等基因编辑工具和分子诊断测试。寡核苷酸合成的进步极大地加速了基因组学和分子生物学的研究,在医学和生物学研究的众多突破中发挥了关键作用。
日本寡核苷酸市场的主要动力是人口中遗传疾病发生率的增加。这就需要探索新的治疗方法,其中基于寡核苷酸的疗法发挥重要作用。例如,利用小干扰 RNA (siRNA) 和反义寡核苷酸的疗法正在研究并应用于治疗杜氏肌肉营养不良症和脊髓性肌肉萎缩症等遗传性疾病。因此,遗传疾病的日益普及不仅在日本而且在更广泛的范围内推动了需求。此外,生物资讯学和资料科学的扩展直接影响寡核苷酸合成领域。分析广泛基因组数据集的能力不断增强,对创新寡核苷酸的合成产生了更大的需求,从而对市场产生了积极影响。此外,寡核苷酸,特别是反义寡核苷酸,已被证明在表观遗传学研究和治疗中有效,促进基因表现调节并有助于良好的市场前景。此外,製药公司、生技公司和研究机构之间的合作和伙伴关係已成为推动遗传疾病寡核苷酸疗法的开发和商业化的关键驱动力。这些合作预计将在预测期内推动区域市场的发展。
市场研究报告也对竞争格局进行了全面分析。报告涵盖了市场结构、关键参与者定位、最佳制胜策略、竞争仪表板和公司评估象限等竞争分析。此外,也提供了所有主要公司的详细资料。
Japan oligonucleotide synthesis market size reached USD 204.9 Million in 2024. Looking forward, IMARC Group expects the market to reach USD 603.0 Million by 2033, exhibiting a growth rate (CAGR) of 11.42% during 2025-2033. The widespread adoption of novel therapeutic strategies, coupled with significant growth of bioinformatics and data science, is primarily driving the market growth.
Oligonucleotide synthesis is the procedure for constructing short DNA or RNA molecules, known as oligonucleotides, with a specific sequence. These sequences can vary in length from just a few bases to approximately 200 nucleotides. This process is typically carried out through chemical synthesis in a controlled laboratory setting, often utilizing solid-phase phosphoramidite chemistry. In this approach, nucleotides are sequentially added to a growing chain, with each addition involving a series of chemical reactions. This technology allows scientists to create tailor-made oligonucleotides for a range of applications, including gene synthesis, polymerase chain reaction (PCR), gene editing tools like CRISPR-Cas9, and molecular diagnostic tests. Advances in oligonucleotide synthesis have greatly accelerated research in genomics and molecular biology, playing a pivotal role in numerous breakthroughs in medical and biological research.
The Japanese market for oligonucleotides is primarily propelled by the increasing incidence of genetic diseases within the population. This necessitates the exploration of novel therapeutic approaches, with a significant role being played by oligonucleotide-based therapies. For example, therapies utilizing small interfering RNAs (siRNAs) and antisense oligonucleotides are being researched and applied in the treatment of genetic disorders like Duchenne muscular dystrophy and spinal muscular atrophy. Consequently, the growing prevalence of genetic diseases is driving demand not only in Japan but also on a wide scale. Furthermore, the expansion of bioinformatics and data science is directly impacting the oligonucleotide synthesis sector. The increasing capacity to analyze extensive genomic datasets is positively influencing the market by generating greater demand for the synthesis of innovative oligonucleotides. Additionally, oligonucleotides, particularly antisense oligonucleotides, have proven effective in epigenetic research and therapy, facilitating gene expression modulation and contributing to a favorable market outlook. Moreover, collaborations and partnerships between pharmaceutical companies, biotechnology firms, and research institutions have become crucial drivers in advancing the development and commercialization of oligonucleotide therapies for genetic diseases. These collaborative efforts are expected to fuel the regional market over the forecasted period.
The market research report has also provided a comprehensive analysis of the competitive landscape. Competitive analysis such as market structure, key player positioning, top winning strategies, competitive dashboard, and company evaluation quadrant has been covered in the report. Also, detailed profiles of all major companies have been provided.