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RNA干扰技术市场:按类型、治疗方法、应用分类 - 2024-2030 年全球预测RNA Interference Technology Market by Type (dsRNA, miRNA, siRNA), Therapeutics (Autoimmune Hepatitis, Hepatitis B and C, Neurological Disorders), Application - Global Forecast 2024-2030 |
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预计2023年RNA干扰技术市场规模为329.2亿美元,预计2024年将达392.5亿美元,2030年将达1,354亿美元,复合年增长率为22.38%。
RNA干扰(RNAi) 技术市场包括使用小 RNA 控制基因表现的系统。该技术可应用于功能基因组学、治疗开发和农业害虫防治。该市场包括各种相关产品,如试剂、siRNA、shRNA、 微型RNA以及基于 RNAi 的研发服务。影响RNAi技术市场成长的主要因素包括基因治疗的进步和遗传疾病盛行率的增加。此外,增加对药物发现和开发过程的投资也支持 RNAi。儘管RNAi技术市场具有巨大的成长潜力,但也存在显着的限制和挑战,例如难以有效地将RNAi分子递送至目标细胞并确保其在体内的稳定性。存在意外基因静默的风险,导致脱靶效应和潜在毒性。然而,基因治疗的进步和遗传疾病盛行率的增加。增加对使用 RNAi 的药物发现和开发过程的投资。
主要市场统计 | |
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基准年[2023] | 329.2亿美元 |
预测年份 [2024] | 392.5亿美元 |
预测年份 [2030] | 1,354亿美元 |
复合年增长率(%) | 22.38% |
类型:利用siRNA进行标靶基因治疗治疗多种疾病
dsRNA 作为 RNAi途径的前驱分子,被细胞机器辨识并加工成较小的 RNAi 有效分子。 miRNA 是一种在植物、动物和一些病毒中发现的小非编码 RNA 分子,其功能是 RNA定序和基因表现的转录后调控。 siRNA是一种双链RNA分子,长度通常为20至25个碱基对,可抑制具有互补碱基序列的特定基因的表达。 siRNA 在 mRNA 层面上针对遗传异常并抑制其表达,使其成为药物开发的优先领域,尤其是在基因治疗领域。 dsRNA 的稳定性和广泛的活性有利于农业用途和病毒防御研究的早期阶段,而 miRNA 在基因调控中的作用则为复杂疾病的治疗和诊断带来了希望。
RNA干扰技术在应用药物发现与开发上的快速普及
药物发现和开发中的 RNAi 主要用于识别基因功能和检验药物标靶。 RNAi 使研究人员能够以可逆且高度特异性的方式有效沉默基因,从而更容易识别特定基因如何参与疾病。 RNAi技术可直接应用于治疗医学领域,以沉默致病基因。这导致了新药的开发,特别是针对单基因突变引起的疾病,以及传统小分子药物和生技药品无效的疾病。 RNAi 的治疗应用适用于已知遗传基础的疾病,例如某些癌症、病毒感染和遗传性疾病。
区域洞察
在美洲, RNA干扰(RNAi)技术取得了重大进展,特别是在生物技术和製药领域。美国是这一领域的领导者,拥有大量促进创新的公司和研究机构。美国国立卫生美国(NIH) 的努力以及致力于 RNAi 的生物技术中心内的合作正在推动进一步的研究和开发。此外,创业投资越来越多地投资于利用 RNAi 进行基因静默的新兴企业,这些公司适用于从癌症治疗到遗传疾病等各种医疗应用。 EMEA(欧洲、中东和非洲)地区呈现出 RNAi 技术的多元化格局,其中欧洲在临床开发和研究方面主导。德国 Silence Therapeutics 和 CureVac 等欧洲生物技术公司为基于 RNAi 的疗法的开发做出了贡献。此外,欧洲药品管理局 (EMA) 为 RNAi 药物的核准提供了强有力的框架,进一步促进了该领域的发展。由欧盟 (EU) 各种框架计划资助的生物医学研究界继续为 RNAi 的理解和应用做出贡献。中东和非洲市场的活动日益活跃,学术机构渴望探索 RNAi 的潜力,以缩小技术差距并解决地方性疾病。亚太地区的 RNAi 技术呈现快速成长,重点是创新和市场扩张。日本和中国处于这一成长的最前沿,在生物技术研究和快速发展的製药业进行投资。政府的倡议以及与国际生物技术公司的合作对该行业的发展做出了重大贡献,学术研究机构正在提供有关 RNAi 机制的基本见解。此外,该地区越来越多地参与全球临床临床实验,这表明该地区致力于将 RNAi 疗法整合到医疗保健系统中。这种整合是由亚太地区动态的监管环境所推动的,并努力应对不断变化的科学环境。
FPNV定位矩阵
FPNV定位矩阵对于评估RNA干扰技术市场至关重要。我们检视与业务策略和产品满意度相关的关键指标,以对供应商进行全面评估。这种深入的分析使用户能够根据自己的要求做出明智的决策。根据评估,供应商被分为四个成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市场占有率分析
市场占有率分析是一种综合工具,可对RNA干扰技术市场中供应商的现状进行深入而详细的研究。全面比较和分析供应商在整体收益、基本客群和其他关键指标方面的贡献,以便更好地了解公司的绩效及其在争夺市场占有率时面临的挑战。此外,该分析还提供了对该行业竞争特征的宝贵见解,包括在研究基准年观察到的累积、分散主导地位和合併特征等因素。这种详细程度的提高使供应商能够做出更明智的决策并制定有效的策略,从而在市场上获得竞争优势。
1. 市场渗透率:提供有关主要企业所服务的市场的全面资讯。
2. 市场开拓:我们深入研究利润丰厚的新兴市场,并分析其在成熟细分市场的渗透率。
3. 市场多元化:提供有关新产品发布、开拓地区、最新发展和投资的详细资讯。
4.竞争评估与资讯:对主要企业的市场占有率、策略、产品、认证、监管状况、专利状况、製造能力等进行全面评估。
5. 产品开发与创新:提供对未来技术、研发活动和突破性产品开发的见解。
1. RNA干扰技术市场规模及预测是多少?
2. RNA干扰技术市场预测期间需要考虑投资的产品、细分市场、应用和领域有哪些?
3. RNA干扰技术市场的技术趋势与法规结构是什么?
4. RNA干扰技术市场主要厂商的市场占有率为何?
5. 进入RNA干扰技术市场的适当型态和策略手段是什么?
[195 Pages Report] The RNA Interference Technology Market size was estimated at USD 32.92 billion in 2023 and expected to reach USD 39.25 billion in 2024, at a CAGR 22.38% to reach USD 135.40 billion by 2030.
The RNA interference (RNAi) technology market encompasses systems that use small RNA molecules to regulate gene expression. This technology is applicable in functional genomics, therapeutic developments, and agriculture for pest control. It encompasses various related products such as reagents, siRNA, shRNA, and microRNA and services for RNAi-based research and development. The key factors influencing the growth of the RNAi technology market include advancements in gene therapy and the increasing prevalence of genetic disorders. Additionally, rising investments in drug discovery and development processes are driven by RNAi. While the RNAi technology market presents significant growth potential, there are notable limitations and challenges, including difficulty in delivering RNAi molecules effectively to targeted cells and ensuring their stability within the body. Risk of unintended gene silencing, leading to off-target effects and potential toxicity. However, advancements in gene therapy and the increasing prevalence of genetic disorders. Rising investments in drug discovery and development processes driven by RNAi.
KEY MARKET STATISTICS | |
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Base Year [2023] | USD 32.92 billion |
Estimated Year [2024] | USD 39.25 billion |
Forecast Year [2030] | USD 135.40 billion |
CAGR (%) | 22.38% |
Type: siRNA's use for targeted gene therapy for treating a multitude of diseases
dsRNA acts as the precursor molecule in the RNAi pathway and is recognized by the cell's machinery to be processed into smaller RNAi-effective molecules. It triggers a natural defense mechanism against RNA viruses and is used in various applications, including agricultural biotechnology and therapeutic developments. miRNA is a small non-coding RNA molecule found in plants, animals, and some viruses, which functions in RNA silencing and post-transcriptional regulation of gene expression. Research into miRNA has surged due to its role in regulating cellular functions and implications in various diseases, including cancer. siRNA is a class of double-stranded RNA molecules, typically 20-25 base pairs in length that interfere with the expression of specific genes with complementary nucleotide sequences. siRNA has been a focus area for drug development, notably in gene therapy, to target and silence genetic abnormalities at the mRNA level. dsRNA's stable nature and broad-spectrum activity make it favorable for agricultural use and the initial stages of viral defense research, while miRNA's role in gene regulation offers promise for complex disease therapy and diagnostics. siRNA's high specificity and reduced off-target effects position it as a frontrunner in targeted gene therapy for many diseases.
Application: Exponential adoption of RNA interference technology for dru discovery & development
The RNAi in drug discovery and development is primarily used to identify the function of genes and validate drug targets. RNAi allows researchers to efficiently silence genes in a reversible and highly specific manner, which facilitates identifying how particular genes contribute to disease. RNAi technology is applied directly to silence disease-causing genes in the therapeutics segment. This has led to the development of new medicines, particularly for diseases caused by single-gene mutations or where traditional small-molecule drugs or biologics have been ineffective. Therapeutic application of RNAi is preferred for diseases with known genetic bases, such as certain types of cancer, viral infections, and inherited genetic disorders.
Regional Insights
In the Americas, RNA interference (RNAi) technology has seen significant advancement, particularly within the biotechnology and pharmaceutical sectors. The United States leads in this space, with a strong presence of companies and research institutions driving innovation. Initiatives by the National Institutes of Health (NIH) and collaborations within RNAi-focused biotech hubs promote further research and development. Additionally, venture capital is increasingly funding startups that leverage RNAi for gene silencing in various medical applications, ranging from cancer therapy to genetic disorders. The EMEA region shows a diverse landscape for RNAi technology, with Europe taking the lead in clinical development and research. European biotech companies, such as Silence Therapeutics and CureVac in Germany, have been instrumental in advancing RNAi-based therapeutics. Moreover, the European Medicines Agency (EMA) provides a robust framework for RNAi drug approval, further facilitating growth in this domain. The biomedical research community, supported by funding from the European Union through various Framework Programmes, continues to contribute to the understanding and application of RNAi. Activity within the Middle East and African markets is emerging, with research primarily driven by academic institutions eager to bridge the technology gap and explore RNAi's potential in tackling region-specific diseases. The Asia-Pacific region demonstrates rapid growth in RNAi technology with a strong emphasis on innovation and market expansion. Japan and China are at the forefront of this growth due to their investments in biotechnology research and quickly evolving pharmaceutical sectors. Government initiatives and collaborations with international biotech firms have significantly contributed to the industry's growth, with academic research institutions providing foundational insights into RNAi mechanisms. Additionally, the region's increasing participation in global clinical trials exhibits a commitment to integrating RNAi therapeutics into their healthcare systems. This integration is facilitated by APAC's dynamic regulatory environment, striving to keep pace with the evolving scientific landscape.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the RNA Interference Technology Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the RNA Interference Technology Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the RNA Interference Technology Market, highlighting leading vendors and their innovative profiles. These include Alnylam Pharmaceuticals, Inc., AMSBIO, Arbutus Biopharma Corporation, Arcturus Therapeutics Holdings Inc., Arrowhead Pharmaceuticals, Inc., AstraZeneca PLC, Atalanta Therapeutics, Bioneer Corporation, CureVac N.V., Dicerna Pharmaceuticals, Inc., Gotham Therapeutics Corp., Gradalis, Inc., Ionis Pharmaceuticals, Inc., Merck KGaA, NeuBase Therapeutics, Inc., Novartis AG, Nutcracker Therapeutics, Inc., Phio Pharmaceuticals Corp., ProQR Therapeutics N.V., Sanofi S.A., Silence Therapeutics PLC, Sirnaomics, Inc., and Thermo Fisher Scientific Inc..
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the RNA Interference Technology Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the RNA Interference Technology Market?
3. What are the technology trends and regulatory frameworks in the RNA Interference Technology Market?
4. What is the market share of the leading vendors in the RNA Interference Technology Market?
5. Which modes and strategic moves are suitable for entering the RNA Interference Technology Market?