市场调查报告书
商品编码
1470946
mRNA 平台市场:按 mRNA 类型、适应症、应用和最终用户划分 - 2024-2030 年全球预测mRNA Platform Market by mRNA Type (Nucleoside-Modified mRNA, Self-Amplifying mRNA, Unmodified mRNA), Indication (Autoimmune Diseases, Cancer, Infectious Diseases), Application, End-User - Global Forecast 2024-2030 |
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预计2023年mRNA平台市场规模为135.2亿美元,2024年达163.3亿美元,预计2030年将达到527.1亿美元,复合年增长率为21.44%。
mRNA(传讯RNA)平台是医学和生物技术领域的一种新方法,主要用于疫苗和治疗方法的开发。 mRNA 充当细胞中 DNA 和各种身体功能所必需的蛋白质之间的分子中介。 mRNA 平台利用合成 mRNA 引导细胞产生特定蛋白质,例如触发免疫反应或刺激细胞修復,而不会改变细胞的 DNA。 mRNA 平台具有加速疫苗开发和生产的能力,由于全球对有效、快速生产疫苗的需求不断增长,对 mRNA 平台的需求也不断增加。只需改变疫苗中 mRNA 的序列,即可客製化 mRNA 疗法来对抗从感染疾病到癌症等多种疾病。这种多功能性为针对各种病症的个人化医疗和治疗方法开闢了新途径。然而,mRNA疫苗和治疗药物需要超低温储存才能保持稳定性,这给配送带来了挑战,特别是在基础设施有限的地区。将 mRNA 有效地递送至细胞而不发生降解是一个相当大的障碍。研究人员不断发现和改进脂质奈米颗粒和其他递送方法来保护 mRNA,直到其到达目标细胞。除了预防性疫苗外,mRNA 技术也正在研究用于癌症治疗、遗传性疾病和自体免疫疾病等治疗应用。
主要市场统计 | |
---|---|
基准年[2023] | 135.2亿美元 |
预测年份 [2024] | 163.3亿美元 |
预测年份 [2030] | 527.1亿美元 |
复合年增长率(%) | 21.44% |
mRNA 类型:核苷修饰的 mRNA 可以透过减少副作用和提高稳定性来平衡免疫反应的有效性。
核苷修饰的 mRNA 会改变 RNA 的组成部分(核苷),以逃避人体的自然防御,这种防御会快速降解 mRNA 或引发不必要的免疫反应。透过修饰这些核苷,科学家可以提高 mRNA 的稳定性和翻译能力,从而使治疗和疫苗讯息更有效地传递到人类细胞。这种类型的 mRNA 已广泛用于 COVID-19 疫苗的开发,因为它能有效引发强烈且持久的免疫反应,且副作用最小。自我扩增的mRNA通常源自于正链RNA病毒的基因组,并且具有在宿主细胞内自我复製的独特能力。这种放大过程意味着可以施用更小的剂量,这可能会降低製造成本并提高可用性。这种 mRNA 不仅编码感兴趣的抗原(例如,需要产生免疫反应的病毒部分),还编码病毒复製机制,允许长期产生抗原,使其更能诱导强烈的免疫反应。未修饰的 mRNA 是用于医学应用的最简单的 mRNA 形式。它不像核苷修饰的 mRNA 那样经历核苷修饰。虽然这使得产生 mRNA 变得更容易,但未修饰的 mRNA 更容易降解,并可能诱导更强的先天免疫反应,为免疫系统提供强大的刺激,但也可能产生副作用。
最终用户:製药公司广泛参与 mRNA 平台的营销和许可。
医院和诊所主要使用基于 mRNA 的治疗和疫苗作为患者照护服务的一部分。他们处于使用 mRNA 平台开发的疫苗的第一线,并在公共卫生工作中发挥关键作用,特别是在大流行期间。此外,医院可以在专门护理下提供针对某些疾病的基于 mRNA 的治疗方法。製药公司正在为基于 mRNA 的药物和疫苗的开发、测试和商业化做出重大贡献。他们正在大力投资研发 (R&D),以探索 mRNA 技术在治疗多种疾病方面的潜力,包括感染疾病以及癌症和遗传性疾病。这些公司处理成功的 mRNA治疗方法的临床试验、监管核准和大规模生产的复杂过程。因此,製药公司是推进 mRNA 平台并将新治疗方法从实验室推向市场的关键机构。研发机构和学术机构进行基础研究,以了解细胞中 mRNA 的机制,探索改善 mRNA 递送和稳定性的创新方法,并开发该技术的新应用。这些研究机构经常与製药公司合作,提供进一步开发基于 mRNA 的治疗方法所需的基础知识。儘管这些机构不参与商业化过程,但它们在扩大对 mRNA 及其潜在应用的科学理解方面所发挥的作用是有价值的。
区域洞察
美洲,特别是美国和加拿大,由于医疗保健支出高、医疗保健基础设施完善以及对研究和创新的高度重视,为 mRNA 平台呈现出成熟的格局。美洲地区是多家生物技术和製药公司的所在地,这些公司经常投资研发项目,以提高 mRNA 平台的安全性、效率和性能。欧盟国家在支持 mRNA 研究和产品核可的法律规范方面处于领先地位。英国、德国和法国等国家在政府、学术界和私营部门之间的合作推动下拥有强大的生物技术部门。欧洲药品管理局 (EMA) 在促进基于 mRNA 的治疗方法的快速核准方面发挥着至关重要的作用。亚太地区是 mRNA 平台技术快速发展的地区,以中国、日本和印度为首。该地区人口众多,对疫苗和治疗方法(包括 mRNA 平台)有巨大需求。政府对改善医疗基础设施的支持非常重要,而对先进治疗方法的认识的提高为 mRNA 平台的扩展提供了重大机会。亚太地区作为疫苗和药物治疗药物製造地的战略地位也为加速 mRNA 平台的采用提供了有利的框架。
FPNV定位矩阵
FPNV定位矩阵对于评估mRNA平台市场至关重要。我们检视与业务策略和产品满意度相关的关键指标,以对供应商进行全面评估。这种深入的分析使用户能够根据自己的要求做出明智的决策。根据评估,供应商被分为四个成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市场占有率分析
市场占有率分析是一种综合工具,可对 mRNA 平台市场供应商的现状进行深入而详细的研究。全面比较和分析供应商在整体收益、基本客群和其他关键指标方面的贡献,以便更好地了解公司的绩效及其在争夺市场占有率时面临的挑战。此外,该分析还提供了对该行业竞争特征的宝贵见解,包括在研究基准年观察到的累积、分散主导地位和合併特征等因素。详细程度的提高使供应商能够做出更明智的决策并制定有效的策略,以获得市场竞争优势。
1. 市场渗透率:提供有关主要企业所服务的市场的全面资讯。
2. 市场开拓:我们深入研究利润丰厚的新兴市场,并分析其在成熟细分市场的渗透率。
3. 市场多元化:提供有关新产品发布、开拓地区、最新发展和投资的详细资讯。
4.竞争评估与资讯:对主要企业的市场占有率、策略、产品、认证、监管状况、专利状况、製造能力等进行全面评估。
5. 产品开发与创新:提供对未来技术、研发活动和突破性产品开发的见解。
1.mRNA平台市场的市场规模与预测是多少?
2. mRNA 平台市场预测期间需要考虑投资的产品、细分市场、应用程式和领域有哪些?
3.mRNA平台市场的技术趋势和法规结构是什么?
4.mRNA平台市场主要厂商的市场占有率为何?
5.进入mRNA平台市场合适的形式和策略手段是什么?
[194 Pages Report] The mRNA Platform Market size was estimated at USD 13.52 billion in 2023 and expected to reach USD 16.33 billion in 2024, at a CAGR 21.44% to reach USD 52.71 billion by 2030.
The mRNA (messenger RNA) platform is a novel approach in the field of medicine and biotechnology, primarily utilized for the development of vaccines and therapeutics. mRNA serves as a molecular intermediary between the DNA in cells and the proteins that are essential for various bodily functions. The mRNA platform leverages synthetic mRNA to instruct cells to produce specific proteins that can trigger an immune response or stimulate cell repair without altering the cell's DNA. The ability of mRNA platforms to accelerate the development and production of vaccines and the rising global need to effectively and quickly produce vaccines has driven the need for mRNA platforms. mRNA therapies can be tailored to fight a wide array of diseases, from infectious diseases to cancer, by simply modifying the mRNA sequence the vaccines carry. This versatility opens up new avenues in personalized medicine and treatments for various conditions. However, mRNA vaccines and therapeutics require ultra-cold storage to remain stable, presenting logistical challenges in distribution, particularly in regions with limited infrastructure. Efficiently delivering mRNA into cells without degradation is a considerable hurdle. Researchers are continuously working on finding and improving lipid nanoparticles and other delivery methods to protect the mRNA until it reaches the target cells. Beyond preventive vaccines, mRNA technology is being explored for therapeutic applications, including cancer treatment, genetic disorders, and autoimmune diseases.
KEY MARKET STATISTICS | |
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Base Year [2023] | USD 13.52 billion |
Estimated Year [2024] | USD 16.33 billion |
Forecast Year [2030] | USD 52.71 billion |
CAGR (%) | 21.44% |
mRNA Type: Ability of nucleoside-modified mRNA to balance immune response efficacy with reduced side effects and offer enhanced stability
Nucleoside-modified mRNA involves the alteration of RNA building blocks (nucleosides) to evade the body's natural defenses, which might otherwise rapidly degrade the mRNA or trigger an unwanted immune response. By modifying these nucleosides, scientists can enhance the stability and translational capacity of the mRNA, making it more effective in delivering the therapeutic or vaccine message to the body's cells. This type of mRNA has been widely used in developing COVID-19 vaccines due to its efficiency in producing a strong and lasting immune response with minimal side effects. Self-amplifying mRNA, often derived from the genome of positive-strand RNA viruses, has the unique ability to replicate itself within the host cells. This amplification process means that smaller doses can be administered, potentially reducing production costs and improving accessibility. In addition to encoding the antigen of interest (such as parts of a virus against which an immune response is desired), this mRNA also encodes the viral replication machinery, enabling the prolonged production of the antigen and thereby inducing a stronger and longer-lasting immune response. Unmodified mRNA is the most straightforward form of mRNA used in medical applications. It does not undergo the nucleoside modifications seen in nucleoside-modified mRNA. While this simplifies its production, unmodified mRNA is more susceptible to degradation and may induce stronger innate immune responses, providing a potent stimulant for the immune system but also potentially leading to adverse effects.
End-User: Extensive involvement of pharmaceutical companies in the marketing and authorization of mRNA platforms
Hospitals and clinics primarily use mRNA-based treatments and vaccines as part of their patient care services. They are at the forefront of administering vaccines developed using the mRNA platform, playing a crucial role in public health initiatives, especially during pandemics. Additionally, mRNA-based therapies for certain diseases might be provided in hospital settings under specialized care. Pharmaceutical companies are instrumental in the development, testing, and commercialization of mRNA-based drugs and vaccines. They invest heavily in research and development (R&D) to explore the potential of mRNA technology in treating a wide array of diseases, beyond just infectious diseases to include cancer and genetic disorders. These companies handle the complex processes of clinical trials, regulatory approvals, and mass production of successful mRNA treatments. Thus, pharmaceutical companies are key institutions in advancing the mRNA platform and bringing new therapies from the lab to the market. Research and academic institutions conduct fundamental research to understand the mechanism of mRNA within the cell, explore innovative approaches to improve mRNA delivery and stability, and develop new applications for this technology. These institutions often collaborate with pharmaceutical companies and provide the foundational knowledge necessary for further development of mRNA-based treatments. While they are not involved in the commercialization process, their role in expanding the scientific understanding of mRNA and its potential applications is valuable.
Regional Insights
The Americas, particularly the United States and Canada, present a mature landscape for the mRNA platform, driven by the high healthcare expenditure, sophisticated healthcare infrastructure, and a strong focus on research and innovation. The Americas region is characterized by the presence of several biotechnology and pharmaceutical companies that frequently invest in R&D programs to improve the safety, efficiency, and performance of mRNA platforms. EU countries lead in regulatory frameworks supporting mRNA research and product approvals. Nations such as the U.K., Germany, and France have strong biotech sectors that are propelled by collaborative efforts between governments, academia, and private sectors. The European Medicine Agency (EMA) plays a pivotal role in facilitating the swift approval of mRNA-based treatments. APAC region is a rapidly evolving landscape for mRNA platform technologies driven by China, Japan, and India. The region's significant population base presents a vast need for vaccines and therapeutic treatments, including mRNA platforms. Government support for improving the healthcare infrastructure notably and a growing awareness of advanced treatment modalities present significant opportunities for the expansion of mRNA platforms. APAC's strategic position as a manufacturing hub for vaccines and drug therapeutics also serves to create a conducive framework for driving the adoption of mRNA platforms.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the mRNA Platform Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the mRNA Platform Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the mRNA Platform Market, highlighting leading vendors and their innovative profiles. These include Accanis Biotech F&E GmbH & Co KG, Aldevron, LLC by Danaher Corporation, Arcturus Therapeutics, Inc., Argos Therapeutics, Inc., AstraZeneca plc, Avectas Limited, BioNTech SE, Catalent, Inc., CRISPR Therapeutics AG, CureVac N.V., Daiichi Sankyo, Dicerna Pharmaceuticals, Inc by Novo Nordisk A/S, eTheRNA, ethris GmbH, Gritstone bio, In-Cell-Art, Merck & Co., Inc., Moderna, Inc., Pfizer Inc., Precision BioSciences, Inc., Regulus Therapeutics Inc., Sangamo Therapeutics, Inc., Sanofi S.A., Tiba Biotech LLC, and Verve Therapeutics.
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the mRNA Platform Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the mRNA Platform Market?
3. What are the technology trends and regulatory frameworks in the mRNA Platform Market?
4. What is the market share of the leading vendors in the mRNA Platform Market?
5. Which modes and strategic moves are suitable for entering the mRNA Platform Market?