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2022-2028 年按应用、最终用户、地区分列的微生物发酵技术展望和预测的全球市场规模、份额、行业趋势分析报告Global Microbial Fermentation Technology Market Size, Share & Industry Trends Analysis Report By Application, By End User, By Regional Outlook and Forecast, 2022 - 2028 |
微生物发酵技术市场规模预计到 2028 年将达到 424 亿美元,预测期内復合年增长率为 5.4%。
许多技术,例如产品或底物评估、显微镜检查、毒性测试或生物量监测,提供了菌株性状和要求的全面信息,从而可以控制特定的发酵过程。帮助您 酵母是单细胞微生物,产生乙醇和二氧化碳参与纸浆发酵,同时产生维生素、氨基酸和其他代谢物帮助细菌生长。
它还具有必需的芳香成分以及蛋白水解和脂解活性。 酵母发酵过程包括啤酒、葡萄酒、苹果酒发酵等酒精发酵和咖啡、麵包、巧克力发酵等非酒精酵母发酵。 酵母是自然界中普遍存在的单细胞真核微生物。 一种称为真菌的生物体,其中还包括蘑菇和霉菌。
COVID-19 影响分析
全球市场已转向微生物菌株生产技术,以增加微生物药物的产量。 此外,政府支持大中小型生物科技公司研究改善肠道环境和增强免疫力的疫苗、药物和产品。 因此,大流行有助于加快与该技术相关的研发过程。 然而,行业停工和供应链中断阻碍了技术在其他领域的使用。 因此,大流行对微生物发酵技术市场产生了一定影响。
市场增长因素
对酒精饮料的需求不断增长
酒店、餐厅、酒馆和酒吧对酒精饮料的需求正在增加。 每年,全球消耗约 4460 亿升葡萄酒、烈酒和啤酒。 啤酒、贮藏啤酒和苹果酒约占酒精消费总量的 4000 亿升,葡萄酒和烈酒分别位居第二和第三位。 随着许多发展中国家对手工烈酒的需求增加,预计酒精饮料行业也会增长。 因此,对酒精饮料的需求增加预计将推动对微生物发酵技术的需求,从而确保市场增长。
食品强化技术的应用取得进展
用平菇进行固态发酵可提高机械控制双低菜粕的蛋白质含□□量,并将芥子油甘和植酸盐含量分别降低高达 98.8% 和 75.8%。 此外,在豆粕 (SBM) 中,固态发酵增加了氨基酸和蛋白质含量,对枯草芽孢桿菌的影响大于对米曲霉的影响。 这些已建立的实验结果扩展了微生物发酵技术的使用案例。 因此,由于这些因素,微生物发酵技术市场有望在未来几年扩大。
市场製约因素
发酵过程问题
由于持续的自然变化,发酵食品会随着时间的推移而受到污染。 但是,即使没有波动,也很容易被污染源污染。 另外,杂质较多,需要多加工。 结果,有害细菌繁殖,有益微生物灭绝,无意间令人不快。 固态发酵等常见发酵工艺也有缺点,例如使用只能耐受低水分含量的微生物以及无法准确监测 SSF。 因此,与微生物发酵过程相关的这些困难可能会阻碍未来几年的市场增长。
应用展望
根据应用,微生物发酵技术市场分为抗生素、益生菌补充剂、单克隆抗体、重组蛋白、生物仿製药、疫苗、□、小分子等。 2021年微生物发酵技术市场中,单克隆抗体领域正迎来大幅增长。 单克隆抗体是用于各种应用的最有用的生物製品之一。 这些化合物的高结合亲和力、选择性和特异性通常是有利的。
最终用户视角
按最终用户划分,微生物发酵技术市场分为生物製药公司、合同研究组织 (CRO)、CMO 和 CDMO 以及学术和研究机构。 2021 年,合同製造组织 (CRO) 和合同开发与製造组织 (CDMO) 细分市场在微生物发酵技术市场的收入份额最大。 CMO 和 CDMO 是生物治疗药物生产商的首选,因为生物加工行业的大部分发明是由中小型企业生产的,这些企业不具备开发这些产品所需的能力、熟练的人力和资源。正在迅速发展进入
区域展望
按地区划分,对北美、欧洲、亚太地区和拉美地区的微生物发酵技术市场进行了分析。 亚太地区将在 2021 年获得微生物发酵技术市场最大的收入份额 这是因为亚洲国家被公认为生物製药行业的外包中心。 据估计,全球 50% 的新生物加工设施由亚洲公司建造,其中包括国内竞争对手和国际巨头。 例如,中国计划建设多个生物加工设施以满足国内需求。
The Global Microbial Fermentation Technology Market size is expected to reach $42.4 billion by 2028, rising at a market growth of 5.4% CAGR during the forecast period.
Microbial fermentation technology is novel, promising, and increasing quickly. This field uses microbes to produce substances with enormous applications in manufacturing biofuels, pharmaceuticals, environmentally friendly materials, fine chemicals, energy, and the food sector. For decades, this technology has been employed in producing highly prized goods. Still, to accomplish the shift to a bio-based society, it is urgently necessary to dramatically speed this technology's development.
Also, there is constant interest in and demand for developing novel microbial fermentation methods for several crucial reasons, including the potential to produce novel compounds and the sustainability element. One of the most crucial elements of contemporary biotechnology is fermentation engineering, which has been widely used in many fields.
Many techniques, like product and substrate evaluation, microscopy, toxicity tests, or biomass monitoring, help to provide a comprehensive image of the traits and requirements of the strains and allow control over specific fermentation processes. Yeasts are single-cell microorganisms that participate in pulque fermentation by producing ethanol and carbon dioxide while also assisting bacterial growth by creating vitamins, amino acids, and other metabolites.
They also provide the necessary aromatic constituents and proteolytic and lipolytic activities. The processes used to ferment yeast include alcoholic fermentations like beer, wine, and cider fermentation, as well as non-alcoholic yeast fermentations like coffee, bread, and chocolate fermentation. Yeasts are unicellular, eukaryotic microfungi found all over the natural world. They are part of the class of organisms known as fungi, which also include mushrooms and molds.
COVID-19 Impact Analysis
Markets worldwide started focusing on microbial strain production technology as it increased the output of microbial-based medications. Additionally, the government supports both small and large biotechnology companies in researching vaccinations, medicines, and products that improve gut health and boost immunity. Therefore, the pandemic aided in speeding up the R&D processes associated with the technology. But the closure of industries and disruptions of supply chains prevented the use of technology in any other sector. As a result, the pandemic had a moderate impact on the microbial fermentation technology market.
Market Growth Factors
Increasing demand for alcoholic beverages
Demand for alcoholic beverages has increased in establishments like hotels, restaurants, taverns, and pubs. Every year, wine, spirits, and beer are consumed worldwide in amounts of about 446 billion liters. Beer, lagers, and cider account for about 400 billion liters of all alcohol consumed, with wine and spirits coming in second and third, respectively. Additionally, the industry for alcoholic beverages is predicted to rise due to the growing demand for artisanal spirits in many developing nations. Therefore, as the demand for alcoholic beverages rises, it will propel the demand for microbial fermentation technology, which will ensure the market's growth.
Rising utilization of technology in food enrichment
The amount of protein in mechanically controlled canola meal increased after solid-state fermentation using Pleurotus ostreatus, and the amounts of glucosinolates and phytate decreased by up to 98.8% and 75.8%, respectively. In soybean meal (SBM), solid-state fermentation boosted the amino acid and protein content, with B. subtilis having a bigger influence than A. oryzae. These established experimental results have expanded the use cases for microbial fermentation technology. Hence, the microbial fermentation technology market will expand in the coming years owing to all these factors.
Market Restraining Factors
Issues associated with the fermentation process
Fermented products can be contaminated over time as they undergo continual natural variations. However, contamination through contamination sources is easy even if no variation occurs. Additionally, the product needs more processing because it is impure. The result was unintended and unpleasant; bad germs grew and multiplied while beneficial microbes perished. Some common fermentation processes, like solid state fermentation, have some drawbacks, including using microorganisms that can only withstand low moisture levels and the inability to precisely monitor SSF. Therefore, such difficulties associated with the microbial fermentation processes may hamper the market's growth in the coming years.
Application Outlook
Based on application, the microbial fermentation technology market is categorized into antibiotics, probiotics supplements, monoclonal antibodies, recombinant proteins, biosimilars, vaccines, enzymes, small molecules, and others. The monoclonal antibodies segment procured a considerable growth rate in the microbial fermentation technology market in 2021. One of the most useful biologics for various applications is monoclonal antibodies. These compounds' high binding affinity, selectivity, and specificity often make them advantageous.
End User Outlook
On the basis of end-user, the microbial fermentation technology market is divided into bio-pharmaceutical companies, contract research organizations (CROs), CMOs & CDMOs, and academic & research institutes. The contract manufacturing organizations (CROs) and contract development & manufacturing organization (CDMOs) segment witnessed the largest revenue share in the microbial fermentation technology market in 2021. CMOs and CDMOs are quickly evolving into the preferred choice for biotherapeutics producers because the majority of the invention in the bioprocess industry is produced by smaller businesses that lack the capacity, skilled personnel, and resources necessary for the development of these products.
Regional Outlook
Region wise, the microbial fermentation technology market is analyzed across North America, Europe, Asia Pacific, and LAMEA. The Asia Pacific segment procured the maximum revenue share in the microbial fermentation technology market in 2021. This results from acknowledging Asian nations as a center for outsourcing in the biopharmaceutical industry. An estimated 50% of new bioprocessing facilities worldwide are being built by Asian businesses, including domestic competitors and international powerhouses. For example, China plans to build several bioprocessing facilities to accommodate domestic demand.
The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Biocon Limited, BioVectra Inc. (H.I.G. Capital, LLC), Danone S.A., F. Hoffmann-La Roche Ltd., Koninklijke DSM N.V., Lonza Group AG, Novozymes A/S (Novo Holdings A/S), Corbion N.V., and Bangalore Biotech Labs Pvt. Ltd. (BiOZEEN).
Strategies Deployed in Microbial Fermentation Technology Market
Feb-2023: Danone opened a new Research and Innovation Center in Paris. The new research center would enable the company to develop and innovate fresh dairy and plant-based products and 'natural mineral water' categories.
Nov-2022: Biocon took over Viatris, Inc., an American pharmaceutical and healthcare corporation. The acquisition enable the company to emerge as a leading biosimilar player with eight commercialized products. Additionally, it would improve the research and development, global-scale manufacturing, and commercialization abilities of the company.
Nov-2022: BioVectra Inc. unveiled single-use fermentation microbial technology. The new technology contains 100 L and 1,000 L single-use fermenters. The single-use fermentation microbial technology would allow the company to provide greater flexibility, faster turnaround times, and increased capacity utilization to its customers.
Jul-2022: Novozymes introduced Innova Apex and Innova Turbo. The two new advanced yeasts are intended to break down fermentation bottlenecks and at the same time decrease the demand for urea, and also improve ethanol yield. The yeasts maximize the fermentation process, thereby enabling ethanol producers to achieve their production targets. The Innova Apex pushes the plant to 36 & dry solids and decreases glycerol by 38%.
Sep-2021: BioVectra signed an agreement with ABEC, a customized process solutions and services provider. The integration of ABEC CSR single-use fermentation solutions would enhance BIOVECTRA's high-growth microbial fermentation processes and would enable the company to offer a turnaround product to product and between batches.
Apr-2019: BioVectra Inc. expanded its geographical footprints in Windsor, Canada. The new manufacturing facility enables the company to manufacture substances to be used in developing treatments for cancer, autoimmune diseases, and diabetes.
Mar-2019: DSM and Cargill, agricultural, financial, and industrial products provider, together launches Avansya, a producer of produce zero-calorie, great-tasting sweeteners through fermentation. Avansya would produce sweet-tasting molecules, such as steviol glycosides Reb M and Reb D through a fermentation process.
Market Segments covered in the Report:
By Application
By End User
By Geography
Companies Profiled
Unique Offerings from KBV Research
List of Figures