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促血红细胞生长素製剂市场-2024年至2029年预测Erythropoietin Drugs Market - Forecasts from 2024 to 2029 |
促血红细胞生长素製剂用于治疗贫血,其特征是红血球数量减少。促血红细胞生长素生成素刺激剂 (ESA) 是促促血红细胞生长素的重组形式,透过细胞培养中的重组 DNA 技术以药理方式产生。 ESA 包括红血球生成素α、Darbepoetin和甲氧基聚乙二醇-红血球生成素生成素β。 pO2 越低,EPO 的形成越明显。当红血球生成减弱时,最常使用 ESA。由于 EPO 可以增加肌肉的氧气供应,因此有些运动员不当地使用 EPO 药物来提高表现。然而,使用 EPO 製剂也会带来严重的健康风险。
促血红细胞生长素製剂市场是一个不断成长的市场,涉及促血红细胞生长素兴奋剂(ESA)的生产和分销。 ESA是促促血红细胞生长素的重组製剂,透过细胞培养中的重组DNA技术在药理上产生。该市场是由贫血发病率上升(特别是在人口老化中)以及对生物相似药的需求不断增长所推动的。市场可以按药物类别、产品、应用和地区进行细分。亚太地区主导全球促血红细胞生长素药物市场。促血红细胞生长素药物市场的主要企业包括 Mayo Clinic、Weefsel Pharma、Trumac Healthcare 和 Incepta Pharmaceuticals Ltd。
由于末期肾功能衰竭治疗、化疗和抗逆转录病毒治疗引起的贫血增加,预计促促血红细胞生长素製剂市场在未来几年将稳定成长。肾臟病细分市场(末期肾臟病和透析)在 2020 年占据了很大份额,预计在预测期内将保持强劲的成长轨迹。癌症、慢性肾臟病(CKD) 和爱滋病毒等慢性疾病的盛行率不断上升,刺激了对促血红细胞生长素产品的需求。但随着2018年促红血球促血红细胞生长素(EPO)生物相似药登陆美国市场、Aranesp在美国的专利到期、价格下跌以及HIF脯氨酰羟化酶抑製剂的上市等,替代产品的开拓正在减缓促促血红细胞生长素製剂市场的成长。由于促血红细胞生长素产品(生物製药)的专利仍然有效,预计促血红细胞生长素产品领域在预测期内将保持其主导地位。
由于人口快速增长和癌症和慢性肾臟病(CKD)等慢性疾病的高盛行率,预计亚太地区将占据促红血球生成促血红细胞生长素製剂市场的主要份额。该地区是促促血红细胞生长素发展前景广阔的市场,大部分促血红细胞生长素原创企业都集中在亚太市场。印度和中国是主要的促血红细胞生长素生物相似药市场,该地区在生物相似药产业中占据最大份额,这些地区的主要製造商开拓新兴国家生产生物相似药。亚太地区的大多数生物相似药製造商有能力以比创新产品低 25-40% 的价格推出促促血红细胞生长素生物相似药。由于促血红细胞生长素素的开发较少,亚太和拉美地区为促血红细胞生长素製造商提供了充满希望的成长机会。
Erythropoietin drugs are used to treat anemia, which is a condition characterized by a low number of red blood cells. The erythropoietin stimulating agents (ESAs) are recombinant versions of erythropoietin produced pharmacologically via recombinant DNA technology in cell cultures. ESAs include epoetin alfa, darbepoetin, and methoxy polyethylene glycol-epoetin beta. The lower the pO2, the more prominent the creation of EPO. ESAs are for the most part shown in conditions where there is debilitated red platelet creation. Some athletes improperly use EPO drugs to boost their performance because EPO increases the availability of oxygen to their muscles. However, the use of EPO drugs can have serious health consequences as well.
The erythropoietin drugs market is a growing market that deals with the production and distribution of erythropoietin-stimulating agents (ESAs). ESAs are recombinant versions of erythropoietin produced pharmacologically via recombinant DNA technology in cell cultures. The market is driven by the increasing incidence of anaemia, particularly in the ageing population, and the growing demand for biosimilars. The market can be segmented based on drug class, product, application, and geography. Asia Pacific dominates the global erythropoietin drugs market. Key players operating in the erythropoietin drugs market include Mayo Clinic, Weefsel Pharma, Trumac Healthcare, and Incepta Pharmaceuticals Ltd.
The erythropoietin drug market is expected to grow steadily in the coming years, driven by the increasing prevalence of anemia caused by end-stage renal disease treatment, chemotherapy, and antiretroviral therapy. The kidney disorders segment (ESRD and dialysis) accounted for a significant share in 2020 and is expected to maintain a strong growth trajectory during the forecast period. The rising incidence of chronic diseases such as cancer, chronic kidney disease (CKD), and HIV is fueling the demand for erythropoietin drugs. However, the introduction of biosimilar erythropoietin (EPO) in the US market in 2018, the impending patent expiry of Aranesp in 2024 in the US, declining prices, and the development of alternative products such as HIF prolyl-hydroxylase inhibitors are moderating the growth of the erythropoietin drugs market. The biologics erythropoietin segment is expected to remain dominant during the forecast period, as patents for these drugs are still in effect.
The Asia Pacific region is expected to hold a significant share of the erythropoietin drugs market, driven by the rapidly increasing population and the high prevalence of chronic diseases such as cancer and chronic kidney disease (CKD). The region is a promising market for the growth of erythropoietin, and the majority of originator companies for erythropoietin are focusing on the Asia-Pacific market. India and China are major erythropoietin biosimilar markets, and the region demonstrates the largest share of the biosimilar industry, owing to the development of biosimilars by major manufacturers in these regions. The majority of biosimilar manufacturers in Asia-Pacific can afford to launch biosimilar versions of erythropoietin at 25-40% less price than innovator products. The Asia-Pacific and LAMEA regions offer promising growth opportunities for erythropoietin manufacturers as these regions are less explored for erythropoietin.
Segmentation