市场调查报告书
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2030 年促红血球生成素药物市场预测:按类型、产品、分销管道、应用、最终用户和地区进行的全球分析Erythropoietin Drugs Market Forecasts to 2030 - Global Analysis By Type (Biosimilars and Biologics), Product (Epoetin-alfa, Epoetin-beta, Darbepoetin-alfa and Other Products), Distribution Channel, Application, End User and By Geography |
根据Stratistics MRC预测,2023年全球促红血球生成素药物市场规模将达107亿美元,预计2030年将达到256亿美元,预测期内复合年增长率为13.2%。
促红血球生成素製剂是一类包含促红血球生成素(肾臟天然产生的荷尔蒙)重组製剂的药物。这些药物旨在刺激和增加红血球合成,可有效控制与贫血相关的症状。促红血球生成素製剂可透过增加红血球数量来治疗虚弱、呼吸困难和头晕等贫血症状,从而改善患者的日常功能。
根据世界卫生组织 (WHO) 的数据,全球 42% 的 5 岁以下儿童和 40% 的孕妇患有贫血。
贫血增加
贫血是一种以红血球数量减少或血红素数量减少为特征的疾病,导致血液携氧能力下降。 EPO 製剂透过促进红血球的产生,在贫血治疗中发挥重要作用。此外,癌症患者通常会使用 EPO 製剂来控制化疗引起的贫血并提高生活品质。这些疾病的日益普及导致贫血的整体负担增加,从而推动了对 EPO 製剂的需求。
可能的副作用
促红血球生成素药物市场面临一个潜在的限制因素:与药物使用相关的副作用的发生。主要关注点之一是与服用促红血球生成素製剂相关的心血管事件风险,例如血栓症和高血压。此外,另一个潜在的副作用是发生纯红血球再生不良性贫血(PRCA),这是一种罕见但严重的疾病,其特征是红血球产生突然停止。
提高医疗保健意识
医疗保健意识的提高是促红血球生成素製剂市场的关键驱动因素。随着患者和医疗保健专业人员对包括贫血在内的健康状况的认识不断提高,人们越来越认识到促红血球生成素製剂在治疗贫血相关併发症中的重要性。此外,越来越多的患者正在寻求及时有效的治疗,其中促红血球生成素製剂发挥重要作用,例如慢性肾臟病。这些因素正在推动市场需求。
新的替代药物
随着科学和医学研究的进展,新的治疗选择,包括非药物干预和替代药物疗法越来越受到关注,挑战促红血球生成素製剂的优越性。此外,市场上生物相似药的供应和采用不断增加可能会导致定价压力和市场占有率竞争,从而影响品牌促红血球生成素製剂的收益。
COVID-19 的影响
由于COVID-19大流行,促红血球生成素製剂市场受到了重大影响。非紧急医疗程序和治疗,包括治疗贫血的促红血球生成素产品,被推迟或推迟,影响了整体市场需求。此外,药品供应链的中断、旅行限制和劳动力短缺阻碍了促红血球生成素产品的生产和分销。
肿瘤学领域预计在预测期内规模最大
预计癌症领域将占据最大份额。癌症患者经常会出现贫血,这可能是疾病本身的结果,也可能是化疗的副作用。促红血球生成素製剂,例如阿法红血球生成素,透过刺激红血球的产生来治疗癌症患者的贫血。此外,促红血球生成素治疗可改善患者健康,并可透过维持足够的携氧红血球来实现更有效的癌症治疗。
生物製药产业预计在预测期内复合年增长率最高。
预计生技药品领域将在预测期内出现良好的成长。生技药品旨在模仿促红血球生成素刺激骨髓中红血球生成的天然能力。促红血球生成素生物製药通常用于治疗与慢性肾臟病、癌症化疗和某些其他医疗状况相关的贫血。此外,生物製药,包括基于促红血球生成素的药物,透过为贫血提供有针对性的有效治疗,为患者的治疗做出了重大贡献。
由于强大的医疗基础设施、技术创新和高普及率,北美在估计期间占据了最大的市场占有率。贫血症的流行,特别是在接受透析的 CKD 患者和接受癌症治疗的患者中,正在推动北美对促红血球生成素产品的需求。此外,该地区也处于生物技术和药物研究的前沿,支持促红血球生成素配方开发的持续创新。
亚太地区预计将在预测期内实现有益成长,因为它对全球製药业做出了重大贡献。中国和印度等国家已成为促红血球生成素製剂生产和消费的主要参与者。该地区的製药业正在经历高度的研发活动,推动创新并推出新的 EPO 配方。此外,亚太地区不断发展的医疗基础设施和不断增加的医疗费用也促进了促红血球生成素製剂市场的成长。
According to Stratistics MRC, the Global Erythropoietin Drugs Market is accounted for $10.7 billion in 2023 and is expected to reach $25.6 billion by 2030 growing at a CAGR of 13.2% during the forecast period. Erythropoietin drugs are a class of medications that include recombinant forms of erythropoietin, a hormone produced naturally in the kidneys. These drugs are designed to stimulate and increase the synthesis of red blood cells, making them effective in managing conditions associated with anaemia. Erythropoietin medications treat anaemia symptoms such as weakness, dyspnea, and vertigo by raising red blood cell counts, leading to improved daily functioning for patients.
According to the World Health Organization (WHO), 42% of children under the age of five and 40% of pregnant women worldwide are anemic.
Rising prevalence of anaemia
Anaemia is a condition characterized by a decrease in the number of red blood cells or a decrease in the amount of haemoglobin, leading to reduced oxygen-carrying capacity in the blood. EPO drugs play a crucial role in managing anaemia by stimulating the production of red blood cells. Moreover, EPO drugs are often prescribed to cancer patients to manage chemotherapy-induced anaemia and improve their quality of life. The increasing prevalence of these conditions contributes to the overall burden of anaemia in the population, thereby driving the demand for EPO drugs.
Potential adverse effects
The erythropoietin drug market faces potential restraints linked to the occurrence of adverse effects associated with the therapeutic use of these drugs. One significant concern is the risk of cardiovascular events, including thrombosis and hypertension, associated with the administration of erythropoietin drugs. Furthermore, another potential adverse effect is the development of pure red cell aplasia (PRCA), a rare but serious condition characterized by a sudden halt in the production of red blood cells.
Increased healthcare awareness
Increased healthcare awareness serves as a pivotal driver in the erythropoietin drugs market. As awareness about health conditions, including anemia, continues to rise among patients and healthcare professionals, there is a heightened recognition of the significance of erythropoietin drugs in managing anemia-associated complications. Moreover, patients are increasingly seeking timely and effective treatments for conditions like chronic kidney disease and other disorders where erythropoietin drugs play a vital role. These factors drive market demand.
Emerging alternatives
As scientific and medical research progresses, new therapeutic options, including non-pharmacological interventions and alternative drug therapies, are gaining attention and posing a challenge to the dominance of erythropoietin drugs. Moreover, the increasing availability and adoption of biosimilars in the market can lead to pricing pressures and market share competition, impacting the revenue of branded erythropoietin drugs.
Covid-19 Impact
The erythropoietin drug market experienced notable impacts from the COVID-19 pandemic. Non-urgent medical procedures and treatments, including those involving erythropoietin drugs for anaemia, were deferred or delayed, affecting the overall market demand. Additionally, disruptions in the pharmaceutical supply chain, restrictions on movement, and workforce shortages posed obstacles to the production and distribution of erythropoietin drugs.
The cancer segment is expected to be the largest during the forecast period
The cancer segment is estimated to hold the largest share. Cancer patients frequently experience anaemia due to the effects of the disease itself or as a side effect of chemotherapy. Erythropoietin drugs, such as epoetin-alfa, are employed to address anaemia in cancer patients by stimulating the production of red blood cells. Moreover, erythropoietin therapies improve the patient's well-being, potentially allowing for more effective cancer treatment by maintaining adequate levels of oxygen-carrying red blood cells.
The biologics segment is expected to have the highest CAGR during the forecast period
The biologics segment is anticipated to have lucrative growth during the forecast period. Biologics are designed to mimic the natural function of erythropoietin in stimulating the production of red blood cells in the bone marrow. Erythropoietin biologics are commonly used to address anaemia associated with chronic kidney disease, cancer chemotherapy, and certain other medical conditions. Additionally, biologics, including erythropoietin-based agents, contribute significantly to patient care by offering targeted and effective treatments for anaemia.
North America commanded the largest market share during the extrapolated period owing to robust healthcare infrastructure, technological innovation, and a high prevalence of conditions. The prevalence of anaemia, particularly in CKD patients undergoing dialysis and individuals undergoing cancer treatments, has fuelled the demand for erythropoietin drugs in North America. Moreover, the region is also at the forefront of biotechnological and pharmaceutical research, driving continuous innovation in erythropoietin drug development.
Asia Pacific is expected to witness profitable growth over the projection period, owing to its significant contribution to the global pharmaceutical industry. Countries like China and India have emerged as key players in the production and consumption of erythropoietin drugs. The region's pharmaceutical sector benefits from robust research and development activities, fostering innovation and the introduction of new EPO formulations. Additionally, the Asia-Pacific's evolving healthcare infrastructure and increasing healthcare expenditure contribute to the growth of the erythropoietin drug market.
Key players in the market
Some of the key players in the Erythropoietin Drugs Market include Johnson & Johnson Services, Inc., AstraZeneca, Amgen, Inc., Novartis AG, Teva Pharmaceutical Industries Ltd., Pfizer Inc, LG Chem, F. Hoffmann-La Roche Ltd., Sun Pharmaceutical Industries Ltd., Intas Pharmaceuticals Ltd., Dr. Reddy's Laboratories Ltd, Ranbaxy Laboratories and Roche Diagnostics.
In November 2023, AstraZeneca announced a collaboration and investment agreement with Cellectis, a clinical-stage biotechnology company, to accelerate the development of next generation therapeutics in areas of high unmet need, including oncology, immunology and rare diseases.
In September 2023, Sun Pharmaceutical Industries Limited announced that it had entered into a licence agreement with American biopharmaceutical company Pharmazz Inc to commercialise an innovative drug, Tyvalzi (Sovateltide) in India.
In January 2022, Amgen and Generate Biomedicines announced a research collaboration agreement to discover and create protein therapeutics for five clinical targets across several therapeutic areas and multiple modalities.
In October 2020, Novartis and Molecular Partners AG announced collaboration in the form of an option and license agreement to develop, manufacture and commercialize Molecular Partners' anti-COVID-19 DARPin® program, consisting of two therapeutic candidates, MP0420 and MP0423.